Yen-ReiAndreaYuMD

Pulmonology • Durham, NC

Critical Care Medicine, Pleural Disease

Medical Instructor in the Department of Medicine, Duke University School of Medicine

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Office
40 Duke Medicine Cir
Durham, NC 27710
Phone+1 919-684-8111
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Education & Training

Duke University HospitalFellowship, Pulmonary Disease and Critical Care Medicine, 2008 - 2011
Massachusetts General HospitalResidency, Internal Medicine, 2005 - 2008
Duke University School of MedicineClass of 2004

Certifications & Licensure

CO State Medical License 2021 - 2025
NC State Medical License 2008 - 2021
MA State Medical License 2007 - 2009
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Publications & Presentations

PubMed

Determining the Architecture of Inflammation in Pulmonary Arterial Hypertension.
Sudarshan Rajagopal, Yen-Rei Yu> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 15
1 citations
Characterization of pulmonary arterial stiffness using cardiac MRI.
Michael T Cain, Michal Schäfer, Sarah Park, Alex J Barker, Daniel Vargas, Kurt R Stenmark, Yen-Rei A Yu, Todd M Bull, D Dunbar Ivy, Jordan R H Hoffman> ;The International Journal of Cardiovascular Imaging. 2024 Feb 1
1 citations
Lethal eosinophilic crystalline pneumonia in mice expressing a stabilized Csf2 mRNA.
Yukitomo Arao, Deborah J Stumpo, Mark J Hoenerhoff, Robert M Tighe, Yen-Rei Yu, Deloris Sutton, Amogh Kashyap, Isabel Beerman, Perry J Blackshear> ;FASEB Journal. 2023 Aug 1
1 citations
Single-Cell Analysis Reveals Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension.
Gayathri Viswanathan, Hélène Fradin Kirshner, Nour Nazo, Saba Ali, Asvin Ganapathi, Ian Cumming, Yonghua Zhuang, Issac Choi, Anmol Warman, Chanpreet Jassal, Susana Alm...> ;American Journal of Respiratory and Critical Care Medicine. 2023 May 15
4 citations
Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models.
Scott Parker, Charlotte McDowall, Luis Sanchez-Perez, Cristina Osorio, Patrick C Duncker, Aaron Briley, Adam M Swartz, James E Herndon 2nd, Yen-Rei A Yu, Roger E McLen...> ;Science Translational Medicine. 2023 Feb 8
2 citations
Tensions in Taxonomies: Current Understanding and Future Directions in the Pathobiologic Basis and Treatment of Group 1 and Group 3 Pulmonary Hypertension.
Sue Gu, Khushboo Goel, Lindsay M Forbes, Vitaly O Kheyfets, Yen-Rei A Yu, Rubin M Tuder, Kurt R Stenmark> ;Comprehensive Physiology. 2023 Jan 30
8 citations
The Pathobiology of Pulmonary Arterial Hypertension.
Sudarshan Rajagopal, Yen-Rei A Yu> ;Cardiology Clinics. 2022 Feb 1
5 citations
Chronic Thromboembolic Pulmonary Hypertension: the Bedside.
Yuri Matusov, Inderjit Singh, Yen-Rei A. Yu, Hyung J. Chun, Bradley A. Maron, Victor F. Tapson, Michael I. Lewis, Sudarshan Rajagopal> ;Current Cardiology Reports. 2021 Aug 19
4 citations
Chronic Thromboembolic Pulmonary Hypertension: the Bench.
George A. Alba, Deepak Atri, Sriranjani Darbha, Inderjit Singh, Victor F. Tapson, Michael I. Lewis, Hyung J. Chun, Yen-Rei A. Yu, Bradley A. Maron, Sudarshan Rajagopal> ;Current Cardiology Reports. 2021 Aug 19
8 citations
NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation.
George A. Alba, Andriy O Samokhin, Rui-Sheng Wang, Ying-Yi Zhang, Bradley M. Wertheim, Elena Arons, Edward A. Greenfield, Martina H Lundberg Slingsby, Julia R. Ceglows...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Jun 25
1 citations
Know Where You Are: Pulmonary Macrophage Locations in the Human Lung.
Robert M. Tighe, Yen-Rei A. Yu> ;American Journal of Respiratory and Critical Care Medicine. 2020 May 15
35 citations
Nonclassical Monocytes Sense Hypoxia, Regulate Pulmonary Vascular Remodeling, and Promote Pulmonary Hypertension.
Yen-Rei A. Yu, Yuryi Malakhau, Chen-Hsin A Yu, Stefan-Laural J Phelan, R. Ian Cumming, Matthew J. Kan, Lan Mao, Sudarshan Rajagopal, Claude A. Piantadosi, Michael D. Gunn> ;Journal of Immunology. 2020 Jan 29
33 citations
Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report.
Robert M. Tighe, Elizabeth F. Redente, Yen-Rei A. Yu, Susanne Herold, Anne I. Sperling, Jeffrey L. Curtis, Ryan Duggan, Suchitra Swaminathan, Hideki Nakano, William J....> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Aug 1
31 citations
Sex Modifies Acute Ozone-Mediated Airway Physiologic Responses.
Anastasiya Birukova, Jaime M. Cyphert-Daly, Robert Ian Cumming, Yen-Rei A. Yu, Kymberly M. Gowdy, Loretta G. Que, Robert M. Tighe> ;Toxicological Sciences. 2019 Jun 1
31 citations
Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations
Vidyalakshmi Chandramohan, Xuhui Bao, Xin Yu, Scott Parker, Charlotte McDowall, Yen-Rei A. Yu, Patrick Healy, Annick Desjardins, Michael D. Gunn, Matthias Gromeier, Sm...> ;Journal for Immunotherapy of Cancer. 2019 May 29
23 citations
Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through β-Arrestin 1.
Zhiyuan Ma, Yen-Rei A. Yu, Cristian T. Badea, Jeffrey J. Kovacs, Xinyu Xiong, Suzy Comhair, Claude A. Piantadosi, Sudarshan Rajagopal> ;Circulation. 2019 Mar 26
332 citations
T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma
Karolina Woroniecka, Pakawat Chongsathidkiet, Kristen E. Rhodin, Hanna Kemeny, Cosette Dechant, S. Harrison Farber, Aladine A. Elsamadicy, Xiuyu Cui, Shohei Koyama, Ch...> ;Clinical Cancer Research. 2018 Sep 1
5 citations
Isolation and Characterization of Human Lung Myeloid Cells.
Yen-Rei A. Yu, Robert M. Tighe> ;Methods in Molecular Biology. 2018 Jan 1
22 citations
Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury
Jamie R. Privratsky, Jiandong Zhang, Xiaohan Lu, Nathan P. Rudemiller, Qingqing Wei, Yen-Rei A. Yu, Michael D. Gunn, Steven D. Crowley> ;American Journal of Physiology. Renal Physiology. 2018 Sep 1
Phenotyping Tumor-Associated Macrophages.
R. Ian Cumming, Yen-Rei A. Yu> ;Methods in Molecular Biology. 2018 Jan 1
237 citations
The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.
Amy E. Baek, Yen-Rei A. Yu, Sisi He, Suzanne E. Wardell, Ching-Yi Chang, Sanghoon Kwon, Ruchita V. Pillai, Hannah B. McDowell, J. Will Thompson, Laura G. Dubois, Patri...> ;Nature Communications. 2017 Oct 11
3 citations
A novel role for primary cilia in airway remodeling
Carol S. Trempus, Weifeng Song, Ahmed Lazrak, Zhihong Yu, Judy Creighton, Bethany M. Young, Rebecca L. Heise, Yen-Rei A. Yu, Jennifer L. Ingram, Robert M. Tighe, Sadis...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2017 May 4
247 citations
A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.
Yen-Rei A. Yu, Emily G. O’Koren, Danielle F. Hotten, Matthew J. Kan, David Kopin, Erik R. Nelson, Loretta G. Que, Michael D. Gunn> ;Plos One. 2016 Mar 3
21 citations
ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation.
Yang S, Lisheng Zhou, Patrick T. Reilly, Shen Sm, Ping He, Xiao-Na Zhu, Chuanlei Li, Luman Wang, Mak Tw, Guo-Qiang Chen, Yen-Rei A. Yu> ;Cell Death & Disease. 2016 Feb 4
162 citations
Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.
Yen-Rei A. Yu, Danielle F. Hotten, Yuryi Malakhau, Ellen Volker, Andrew J. Ghio, Paul W. Noble, Monica Kraft, John W. Hollingsworth, Michael D. Gunn, Robert M. Tighe> ;American Journal of Respiratory Cell and Molecular Biology. 2016 Jan 1
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Hospital Affiliations

Duke University HospitalDurham, North Carolina
Duke Regional HospitalDurham, North Carolina
Durham Veterans Affairs Medical CenterDurham, North Carolina
University of Colorado HospitalAurora, Colorado