YiSunMD

PubMed

• Mutual inactivation of two RING-finger-type E3 ubiquitin ligases during cell cycle progression.
  Shizhen Zhang, Yi Sun> ;Molecular & Cellular Oncology. 2021 Jan 2
• 8 citations
  Inactivation of ribosomal protein S27-like impairs DNA interstrand cross-link repair by destabilization of FANCD2 and FANCI.
  Siyuan Sun, Hengqian He, Yuanyuan Ma, Jie Xu, Guoan Chen, Yi Sun, Xiufang Xiong> ;Cell Death & Disease. 2020 Oct 13
• 7 citations
  Neddylation modification of ribosomal protein RPS27L or RPS27 by MDM2 or NEDP1 regulates cancer cell survival.
  Xiufang Xiong, Danrui Cui, Yanli Bi, Yi Sun, Yongchao Zhao> ;FASEB Journal. 2020 Oct 1
• 10 citations
  The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance
  Shizhen Zhang, Yanwen Shen, Hua Li, Chao Bi, Yilun Sun, Xiufang Xiong, Wenyi Wei, Yi Sun> ;Cell Reports. 2020 Sep 8
• 4 citations
  Relationship between sleep architecture and severity of obstructive sleep apnea
  Biwen Wu, Jiaye Cai, Ying Yao, Yu Pan, Liuqing Pan, Lisan Zhang, Yi Sun> ;Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 2020 Aug 25
• 90 citations
  Functional characterization of SOX2 as an anticancer target
  Shizhen Zhang, Xiufang Xiong, Yi Sun> ;Signal Transduction and Targeted Therapy. 2020 Jul 29
• [Targeting Cullin-RING E3 ligases for anti-cancer therapy: efforts on drug discovery].
  Qing Yu, Xiufang Xiong, Yi Sun> ;Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 2020 Jun 8
• 44 citations
  Anticancer drug discovery by targeting cullin neddylation
  Qing Yu, Yihan Jiang, Yi Sun> ;Acta Pharmaceutica Sinica. B. 2020 May 1
• 74 citations
  Engineered algae: A novel oxygen-generating system for effective treatment of hypoxic cancer
  Yue Qiao, Fei Yang, Tingting Xie, Zhen Du, Danni Zhong, Yuchen Qi, Yangyang Li, Wanlin Li, Zhimin Lu, Jianghong Rao, Yi Sun, Min Zhou> ;Science Advances. 2020 May 1
• 6 citations
  Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras-PDAC model.
  Qiang Zhang, Dongping Wei, Mingjia Tan, Haomin Li, Meredith A. Morgan, Yi Sun> ;Neoplasia. 2020 Apr 24
• 32 citations
  Cullin-RING Ligase 5: Functional characterization and its role in human cancers
  Yongchao Zhao, Xiufang Xiong, Yi Sun> ;Seminars in Cancer Biology. 2020 Apr 22
• 19 citations
  Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
  Qing Yu, Zhiguo Hu, Yanwen Shen, Yihan Jiang, Peichen Pan, Tingjun Hou, Zhen-Qiang Pan, Jing Huang, Yi Sun> ;Neoplasia. 2020 Apr 1
• 14 citations
  Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells.
  Xiaochen Zhou, Sumin Han, Kari Wilder-Romans, G. Sun, Hong Zhu, Xiaoqiang Liu, Mingjia Tan, Gongxian Wang, Felix Y. Feng, Yi Sun> ;Neoplasia. 2020 Mar 4
• 17 citations
  Targeting oncogenic SOX2 in human cancer cells: therapeutic application.
  Shizhen Zhang, Yi Sun> ;Protein & Cell. 2020 Mar 4
• 11 citations
  SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II.
  Jianfeng Shu, Danrui Cui, Ying Ma, Xiufang Xiong, Yi Sun, Yongchao Zhao> ;Oncogenesis. 2020 Feb 3
• 20 citations
  DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals.
  Xiaoyu Chen, Xiufang Xiong, Danrui Cui, Fei Yang, Dongping Wei, Haomin Li, Jianfeng Shu, Yanli Bi, Xiaoqing Dai, Longyuan Gong, Yi Sun, Yongchao Zhao> ;Oncogene. 2020 Feb 1
• 49 citations
  FBXW7 Confers Radiation Survival by Targeting p53 for Degradation
  Danrui Cui, Xiufang Xiong, Jianfeng Shu, Xiaoqing Dai, Yi Sun, Yongchao Zhao> ;Cell Reports. 2020 Jan 14
• 19 citations
  Neddylation-Independent Activities of MLN4924.
  Hongmei Mao, Yi Sun> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 18 citations
  Cullin RING Ligase 5 (CRL-5): Neddylation Activation and Biological Functions.
  Shizhen Zhang, Yi Sun> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 15 citations
  Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth.
  Shuaishuai Ni, Xin Chen, Qing Yu, Yixiang Xu, Zhiguo Hu, Junqian Zhang, Wenjuan Zhang, Baoli Li, Xi Yang, Fei Mao, Jing Huang, Yi Sun, Jian Li, Lijun Jia> ;European Journal of Medicinal Chemistry. 2020 Jan 1
• 9 citations
  Targeting DCN1-UBC12 Protein-Protein Interaction for Regulation of Neddylation Pathway.
  Haibin Zhou, Jianfeng Lu, Chao-Yie Yang, Yi Sun, Shaomeng Wang> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 59 citations
  The FBXW2–MSX2–SOX2 axis regulates stem cell property and drug resistance of cancer cells
  Yuan Yin, Chuan-Ming Xie, Hua Li, Mingjia Tan, Guoan Chen, Rachel Schiff, Xiufang Xiong, Yi Sun> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct 8
• 16 citations
  SAR Studies on Aromatic Acylhydrazone-Based Inhibitors of Fungal Sphingolipid Synthesis as Next-Generation Antifungal Agents
  Krupanandan Haranahalli, Cristina Lazzarini, Yi Sun, Julia Zambito, Senuri Pathiranage, J. Brian McCarthy, John P. Mallamo, Maurizio Del Poeta, Iwao Ojima> ;Journal of Medicinal Chemistry. 2019 Aug 1
• 7 citations
  FBXW7 E3 ubiquitin ligase: degrading, not degrading, or being degraded
  Huiyin Lan, Yi Sun> ;Protein & Cell. 2019 Jul 24
• 48 citations
  LSD1 destabilizes FBXW7 and abrogates FBXW7 functions independent of its demethylase activity.
  Huiyin Lan, Mingjia Tan, Qiang Zhang, Fei Yang, Siyuan Wang, Hua Li, Xiufang Xiong, Yi Sun> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jun 18
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