Dr. Sadovsky is on Doximity
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Office
300 Halket Street
Pittsburgh, PA 15213Phone+1 314-747-3000Fax+1 314-747-1256- Is this information wrong?
Summary
- Yoel Sadovsky received his MD degree from the Hebrew University in 1986, followed by OBGYN residency at Washington University and maternal-fetal medicine and postdoctoral research fellowships at UCSF. He then returned to Washington University and served as Director, Division of Maternal-Fetal Medicine and Ultrasound between 1999-2007. In 2007, he assumed Directorship of Magee-Womens Research Institute (MWRI) at the University of Pittsburgh, and Vice Chair (Research), Department of Obstetrics, Gynecology and Reproductive Sciences.
Building on his clinical expertise in maternal-fetal medicine, Dr. Sadovsky seeks to decipher molecular processes underlying placental development and function, and their impact on early human development. His research integrates molecular and informatics tools to decipher trophoblast adaption to cellular injury. A primary focus is the function of trophoblast-specific microRNAs and other ncRNAs, which are packaged in extracellular vesicles and communicate genomic material among the fetal, placental, and maternal compartments. Dr. Sadovsky also interrogates trophoblast utilization of lipidic fuels, and the role of phospholipids in placental injury. His investigation has resulted in the publication of more than 190 peer-reviewed articles as well as chapters and reviews. He is the Associate Dean for Women’s Health Research and Reproductive Sciences at the Univ. of Pittsburgh, and in 2015 was honored by the University as a Distinguished Professor in OBGYN and Reproductive Sciences.
Dr. Sadovsky has served on several NIH study sections, the NICHD Division of Intramural Research 2013 Review Panel, chaired the NICHD Maternal-Fetal Biology Research Study Section, and the NICHD Genomic and Proteomic Network for Preterm Birth Research steering committee. He has served as a member of the Advisory Council for NICHD and March of Dimes, and the NICHD Board of Scientific Directors, and this year appointed to the NIH’s Advisory Committee on Research on
Education & Training
- University of California (San Francisco)Fellowship, Maternal-Fetal Medicine, 1993
- Washington University/B-JH/SLCH ConsortiumResidency, Obstetrics and Gynecology, 1986 - 1990
- The Hebrew University of Jerusalem Hadassah Medical SchoolClass of 1986
Certifications & Licensure
- CA State Medical License 1990 - 2025
- PA State Medical License 2007 - 2024
- MO State Medical License 1993 - 2021
- IL State Medical License 1987 - 2020
- American Board of Obstetrics and Gynecology Obstetrics & Gynecology
- American Board of Obstetrics and Gynecology Maternal-Fetal Medicine
Publications & Presentations
PubMed
- 1 citationsLipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes.Namit Chaudhary, Alexandra N Newby, Mariah L Arral, Saigopalakrishna S Yerneni, Samuel T LoPresti, Rose Doerfler, Daria M Strelkova Petersen, Catalina Montoya, Julie S...> ;Proceedings of the National Academy of Sciences of the United States of America. 2024 Mar 12
- 1 citationsStrikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Ce...Karumanchi, A., Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A ...> ;Angewandte Chemie. 2024 Feb 26
- High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT.Joseph Rufo, Peiran Zhang, Zeyu Wang, Yuyang Gu, Kaichun Yang, Joseph Rich, Chuyi Chen, Ruoyu Zhong, Ke Jin, Ye He, Jianping Xia, Ke Li, Jiarong Wu, Yingshi Ouyang, Yo...> ;Microsystems & Nanoengineering. 2024 Jan 1
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Authored Content
- Advancing Human Health in the Decade Ahead: Pregnancy as a Key Window for Discovery A Burroughs Wellcome Fund Pregnancy Think-TankJune 2020
- Advancing Human Health in the Decade Ahead: Pregnancy as a Key Window for Discovery A Burroughs Wellcome Fund Pregnancy Think-TankOctober 2018
Press Mentions
- Magee-Womens Summit to Explore Research into Women’s HealthJuly 1st, 2021
- UPMC: Magee-Womens Summit Convenes with $1M Magee PrizeJune 27th, 2021
- New Genomic Study of Placenta Finds Deep Links to CancerApril 8th, 2021
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Grant Support
- Placental Injury And MicrornaEunice Kennedy Shriver National Institute Of Child Health &Human Development2010–2011
- Regulation Of Trophoblast Differentiation And FunctionNational Institute Of Environmental Health Sciences2007–2011
- Placental Injury And AdaptationEunice Kennedy Shriver National Institute Of Child Health &Human Development2008
- The Role Of Microrna In Placental DifferentiationEunice Kennedy Shriver National Institute Of Child Health &Human Development2007
- The Role Of Microrna In Placental DifferentiationEunice Kennedy Shriver National Institute Of Child Health &Human Development2006–2007
- Placental Injury And AdaptationEunice Kennedy Shriver National Institute Of Child Health &Human Development2004–2007
- Regulation Of Trophoblast Differentiation And FunctionNational Institute Of Environmental Health Sciences2001–2007
- EGR-1 And SF-1 And LH Beta ProductionEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2003
- Activation Function Of Steroidogenic Factor 1Eunice Kennedy Shriver National Institute Of Child Health &Human Development1997–2001
Professional Memberships
- Fellow
Hospital Affiliations
- UPMC Presbyterian ShadysidePittsburgh, Pennsylvania
- UPMC Magee-Womens HospitalPittsburgh, Pennsylvania
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