YongJaeLeeMD

Emergency Medicine • Naples, FL

Physician

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Office
350 7th St N
Naples, FL 34102
Phone+1 239-436-5151

Fax+1 239-436-5914
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Education & Training

Johns Hopkins UniversityResidency, Emergency Medicine, 2004 - 2007
Beth Israel Deaconess Medical Center/Harvard Medical SchoolResidency, Anesthesiology, 2003 - 2004
UMass Chan Medical SchoolInternship, Internal Medicine, 2002 - 2003
University of Kansas School of MedicineClass of 2002

Certifications & Licensure

FL State Medical License 2007 - 2025
American Board of Emergency Medicine Emergency Medicine

Publications & Presentations

PubMed

5 citations
Improved chemosensitivity following mucolytic therapy in patient-derived models of mucinous appendix cancer.
Ashok K. Dilly, Robin Frederick, Anuleka Elapavaluru, Sachin Velankar, Hima Makala, T. Kevin Hitchens, Lesley M. Foley, Jianxia Guo, Jan H. Beumer, Lora H. Rigatti, Yo...> ;Translational Research. 2021 Mar 1
8 citations
Glucose deprivation-induced endoplasmic reticulum stress response plays a pivotal role in enhancement of TRAIL cytotoxicity
Kalishwaralal Kalimuthu, Jin Hong Kim, Yong Seok Park, Xu Luo, Lin Zhang, Ja Lok Ku, Yong J. Lee, M. Haroon A. Choudry> ;Journal of Cellular Physiology. 2021 Feb 15
9 citations
The interplay between apoptosis and ferroptosis mediated by ER stress.
Yong J. Lee> ;Apoptosis. 2020 Nov 2
5 citations
Synergistic apoptosis following endoplasmic reticulum stress aggravation in mucinous colon cancer.
Ashok K. Dilly, Yong J. Lee, David L. Bartlett, Haroon A. Choudry> ;Orphanet Journal of Rare Diseases. 2020 Aug 18
51 citations
BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis
Young Sun Lee, Kalishwaralal Kalimuthu, Yong Seok Park, Xu Luo, David L. Bartlett, Yong J. Lee, M. Haroon A. Choudry> ;Apoptosis. 2020 Oct 1
22 citations
Ferroptotic agent-induced endoplasmic reticulum stress response plays a pivotal role in the autophagic process outcome.
Young Sun Lee, Kalishwaralal Kalimuthu, Yong Seok Park, Hima Makala, Simon C. Watkins, David L. Bartlett, Yong Tae Kwon, Yong J. Lee, M. Haroon A. Choudry> ;Journal of Cellular Physiology. 2020 Jan 27
6 citations
Rational application of targeted therapeutics in mucinous colon/appendix cancers with positive predictive factors
Ashokkumar Dilly, Yong J. Lee, David L. Bartlett, Haroon A. Choudry> ;Cancer Medicine. 2020 Jan 20
44 citations
Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5
Young Sun Lee, Dae Hee Lee, So Yeon Jeong, Seong Hye Park, Sang Cheul Oh, Yong Seok Park, Jian Yu, Haroon A. Choudry, David L. Bartlett, Yong J. Lee> ;Journal of Cellular Biochemistry. 2019 Jan 1
196 citations
Ferroptosis-Induced Endoplasmic Reticulum Stress: Cross-talk between Ferroptosis and Apoptosis.
Young Sun Lee, Dae Hee Lee, Haroon A. Choudry, David L. Bartlett, Yong J. Lee> ;Molecular Cancer Research. 2018 Jul 1
29 citations
Crosstalk between Apoptosis and Autophagy is Regulated by the Arginylated BiP/Beclin-1/p62 Complex
Xinxin Song, Dae Hee Lee, Ashok K. Dilly, Young Sun Lee, Haroon A. Choudry, Yong Tae Kwon, David L. Bartlett, Yong J. Lee> ;Molecular Cancer Research. 2018 Jul 1
16 citations
PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5
Dae Hee Lee, Daeho Kim, Sung Tae Kim, Soyeon Jeong, Jung Lim Kim, Sang Mi Shim, Ah Jung Heo, Xinxin Song, Zong Sheng Guo, David L. Bartlett, Sang Cheul Oh, Junho Lee, ...> ;Autophagy. 2018 Jul 23
Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression.
Hong, S. H.,Lee, D. H.,Lee, Y. S.,Jo, M. J.,Jeong, Y. A.,Kwon, W. T.,Choudry, H. A.,Bartlett, D. L.,Lee, Y. J.> ;Oncotarget. 2018 Feb 01
13 citations
Targeting G-protein coupled receptor-related signaling pathway in a murine xenograft model of appendiceal pseudomyxoma peritonei.
Ashok K. Dilly, Yong J. Lee, Z S Guo, Herbert J. Zeh, David L. Bartlett, Haroon A. Choudry> ;Oncotarget. 2017 Nov 15
4 citations
Corrigendum to: Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition (EMBO reports, (2017), 18, 1, (150-168), 10.15252/embr.201642360)
Young Dong Yoo, Dae Hee Lee, Hyunjoo Cha-Molstad, Hyungsin Kim, Su Ran Mun, Changhoon Ji, Seong H. Park, Ki Sa Sung, Seung Ah Choi, Joonsung Hwang, Deric M. Park, Seun...> ;EMBO Reports. 2017 Sep 1
28 citations
Cancer Stem Cells Protect Non‐Stem Cells From Anoikis: Bystander Effects
Seog Young Kim, Se Hoon Hong, Per H. Basse, Chuanyue Wu, David L. Bartlett, Yong Tae Kwon, Yong J. Lee> ;Journal of Cellular Biochemistry. 2016 Oct 1
11 citations
TRAIL‐Induced Caspase Activation is a Prerequisite for Activation of the Endoplasmic Reticulum Stress‐Induced Signal Transduction Pathways
Dae Hee Lee, Ki Sa Sung, Zong Sheng Guo, William T. Kwon, David L. Bartlett, Sang Cheul Oh, Yong Tae Kwon, Yong J. Lee> ;Journal of Cellular Biochemistry. 2016 May 1
27 citations
Targeting hypoxia-mediated mucin 2 production as a therapeutic strategy for mucinous tumors.
Ashok K. Dilly, Yong J. Lee, Herbert J. Zeh, Zong Sheng Guo, David L. Bartlett, Haroon A. Choudry> ;Translational Research. 2016 Mar 1
10 citations
Secretory TRAIL-armed Natural Killer Cell-based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft
Xinxin Song, Se Hoon Hong, William T. Kwon, Lisa Bailey, Per H. Basse, David L. Bartlett, Yong Tae Kwon, Yong J. Lee> ;Molecular Cancer Therapeutics. 2016 Jan 1
6 citations
Hypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53.
Xinxin Song, Ashok K. Dilly, Haroon A. Choudry, David L. Bartlett, Yong Tae Kwon, Yong J. Lee> ;Molecular Cancer Research. 2015 Dec 1
23 citations
Mitogen-activated protein kinase inhibition reduces mucin 2 production and mucinous tumor growth.
Ashok K. Dilly, Xinxin Song, Herbert J. Zeh, Z S Guo, Yong J. Lee, David L. Bartlett, Haroon A. Choudry> ;Translational Research. 2015 Oct 1
Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopa...
Kano, S. I.,Yuan, M.,Cardarelli, R. A.,Maegawa, G.,Horiuchi, Y.,Higurashi, N.,Gaval-Cruz, M.,Wilson, A. M.,Tristan, C.,Kondo, M. A.,Chen, Y.,Koga, M.,Obie, C.,Ishizuka...> ;Curr. Mol. Med.. 2015 Mar 04
39 citations
HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells
Dae Hee Lee, Ki Sa Sung, David L. Bartlett, Yong Tae Kwon, Yong J. Lee> ;Cellular Signalling. 2015 Feb 1
41 citations
Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer
Xinxin Song, S. Y. Kim, Lin Zhang, Daolin Tang, David L. Bartlett, Yong Tae Kwon, Yong J. Lee> ;Cell Death & Disease. 2014 Oct 30
59 citations
RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer.
Rui Kang, Wen Hou, Qiuhong Zhang, Ruochan Chen, Yong J. Lee, David L. Bartlett, Michael T. Lotze, Daolin Tang, H.J. Zeh> ;Cell Death & Disease. 2014 Oct 23
46 citations
Gingerol sensitizes TRAIL-induced apoptotic cell death of glioblastoma cells
Dae Hee Lee, Dong-Wook Kim, Chang Hwa Jung, Yong J. Lee, Daeho Park> ;Toxicology and Applied Pharmacology. 2014 Sep 15
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Hospital Affiliations

NCH Baker HospitalNaples, Florida