YongZhangMD

Internal Medicine • Martinez, CA

MD, SNF physician Kaiser DSA

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Office
200 Muir Road
Martinez, CA 94553
Phone+1 925-229-7756

Fax+1 925-229-7757
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Internal Medicine, 1996 - 1999
Catholic University of LeuvenClass of 1987

Certifications & Licensure

CA State Medical License 1998 - 2024
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011

Clinical Trials

Endostar Combined With Concurrent Chemoradiotherapy For Locally Advanced Cervical Carcinoma Start of enrollment: 2017 Mar 01
Unknown status
Phase 3
A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy Start of enrollment: 2017 Dec 27
Active, not recruiting
Phase 2, Phase 3

Publications & Presentations

PubMed

10 citations
Expanding the toolbox of exosome-based modulators of cell functions.
Qinqin Cheng, Zhefu Dai, Xiaojing Shi, Xinping Duan, Yiling Wang, Tianling Hou, Yong Zhang> ;Biomaterials. 2021 Oct 1
3 citations
Site-specific antibody-drug conjugates with variable drug-to-antibody-ratios for AML therapy
Zhefu Dai, Xiao-Nan Zhang, Qinqin Cheng, Fan Fei, Tianling Hou, Jiawei Li, Alireza Abdolvahabi, Junji Watanabe, Hua Pei, Goar Smbatyan, Jianming Xie, Heinz-Josef Lenz,...> ;Journal of Controlled Release. 2021 Aug 10
5 citations
A two-trick pony: lysosomal protease cathepsin B possesses surprising ligase activity
Tyler R. Lambeth, Zhefu Dai, Yong Zhang, Ryan R. Julian> ;RSC Chemical Biology. 2021 Apr 15
11 citations
A Bifunctional NAD+ for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins.
Albert T. Lam, Xiao-Nan Zhang, Valentine V. Courouble, Timothy S. Strutzenberg, Hua Pei, Bangyan L. Stiles, Stan G. Louie, Patrick R. Griffin, Yong Zhang> ;ACS Chemical Biology. 2021 Feb 1
5 citations
A poly-ADP-ribose polymer-based antibody-drug conjugate
Xiaojing Shi, Xiao-Nan Zhang, Jingwen Chen, Qinqin Cheng, Hua Pei, Stan G. Louie, Yong Zhang> ;Chemical Science. 2020 Sep 2
3 citations
A humanized antibody inhibitor for cathepsin L
Xiaojing Shi, Yong Zhang> ;Protein Science. 2020 Sep 1
13 citations
Anti-FLT3 nanoparticles for acute myeloid leukemia: Preclinical pharmacology and pharmacokinetics.
Mincheol Park, Vijaya Pooja Vaikari, Albert T. Lam, Yong Zhang, John Andrew MacKay, Houda Alachkar> ;Journal of Controlled Release. 2020 Aug 10
22 citations
Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases
Zhefu Dai, Xiao-Nan Zhang, Fariborz Nasertorabi, Qinqin Cheng, Jiawei Li, Benjamin B. Katz, Goar Smbatyan, Hua Pei, Stan G. Louie, Heinz-Josef Lenz, Raymond C. Stevens...> ;Science Advances. 2020 Jun 1
9 citations
Reprogramming extracellular vesicles with engineered proteins.
Xiaojing Shi, Qinqin Cheng, Yong Zhang> ;Methods. 2020 May 1
9 citations
Rational Design of a Humanized Antibody Inhibitor of Cathepsin B.
Zhefu Dai, Qinqin Cheng, Yong Zhang> ;Biochemistry. 2020 Mar 26
121 citations
Genetically Engineered Cell-Derived Nanoparticles for Targeted Breast Cancer Immunotherapy.
Xiaojing Shi, Qinqin Cheng, Tianling Hou, Menglu Han, Goar Smbatyan, Julie E. Lang, Alan L. Epstein, Heinz-Josef Lenz, Yong Zhang> ;Molecular Therapy. 2020 Feb 5
12 citations
Reprogramming Exosomes for Immunotherapy.
Qinqin Cheng, Xiaojing Shi, Yong Zhang> ;Methods in Molecular Biology. 2020 Jan 1
19 citations
A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation.
Xiao-Nan Zhang, Qinqin Cheng, Jingwen Chen, Albert T. Lam, Yanran Lu, Zhefu Dai, Hua Pei, Nikolai M. Evdokimov, Stan G. Louie, Yong Zhang> ;Nature Communications. 2019 Sep 13
26 citations
Identification of salivary metabolites for oral squamous cell carcinoma and oral epithelial dysplasia screening from persistent suspicious oral mucosal lesions
Shigeo Ishikawa, David T.W. Wong, Masahiro Sugimoto, Frederico O. Gleber-Netto, Feng Li, Michael Tu, Yong Zhang, David Akin, Mitsuyoshi Iino> ;Clinical Oral Investigations. 2019 Sep 1
1 citations
Chemoenzymatic Preparation of 4'-Thioribose NAD.
Xiao-Nan Zhang, Zhefu Dai, Qinqin Cheng, Yong Zhang> ;Current Protocols in Nucleic Acid Chemistry. 2019 Jun 1
6 citations
Genome-wide analysis of Fusarium verticillioides reveals inter-kingdom contribution of horizontal gene transfer to the expansion of metabolism.
Shan Gao, Scott E. Gold, Jennifer H. Wisecaver, Yong Zhang, Li Guo, Li-Jun Ma, Antonis Rokas, Anthony E. Glenn> ;Fungal Genetics and Biology. 2019 Apr 3
74 citations
Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition.
Peng Wu, Tongtong Zhang, Baoyu Liu, Panyu Fei, Lei Cui, Rui Qin, Huaying Zhu, Danmei Yao, Ryan J. Martinez, Wei Hu, An Chenyi, Yong Zhang, Junwei Liu, Jiawei Shi, Juan...> ;Molecular Cell. 2019 Mar 7
3 citations
Clinical value of neutrophil-to-lymphocyte ratio as a predictor of prognosis of RetroNectin®-activated cytokine-induced killer cell therapy in advanced non-small-cell ...
Lingdi Zhao, Tiepeng Li, Yonghao Yang, Yong Zhang, Wei Li, Lu Han, Yiman Shang, Hongwei Lin, Xiubao Ren, Quanli Gao> ;Immunotherapy. 2019 Mar 1
37 citations
The PROTEIN PHOSPHATASE4 Complex Promotes Transcription and Processing of Primary microRNAs in Arabidopsis.
Suikang Wang, Li Quan, Shaofang Li, Chenjiang You, Yong Zhang, Lei Gao, Liping Zeng, Lin Liu, Yanhua Qi, Beixin Mo, Xuemei Chen> ;The Plant Cell. 2019 Feb 1
167 citations
Reprogramming Exosomes as Nanoscale Controllers of Cellular Immunity
Qinqin Cheng, Xiaojing Shi, Menglu Han, Goar Smbatyan, Heinz-Josef Lenz, Yong Zhang> ;Journal of the American Chemical Society. 2018 Nov 19
13 citations
Facile chemoenzymatic synthesis of a novel stable mimic of NAD.
Zhefu Dai, Xiao-Nan Zhang, Fariborz Nasertorabi, Qinqin Cheng, Hua Pei, Stan G. Louie, Raymond C. Stevens, Yong Zhang> ;Chemical Science. 2018 Nov 14
Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents.
Zhang, Y.,Zhao, Y.,Tebben, A. J.,Sheriff, S.,Ruzanov, M.,Fereshteh, M. P.,Fan, Y.,Lippy, J.,Swanson, J.,Ho, C. P.,Wautlet, B. S.,Rose, A.,Parrish, K.,Yang, Z.,Donnell,...> ;ACS Med Chem Lett. 2018 Nov 16
6 citations
Combination of PD-1 blockade and RetroNectin®-activated cytokine-induced killer in preheavily treated non-small-cell lung cancer: a retrospective study.
Lingdi Zhao, Lu Han, Yong Zhang, Tiepeng Li, Yonghao Yang, Wei Li, Yiman Shang, Hongwei Lin, Quanli Gao> ;Immunotherapy. 2018 Oct 23
15 citations
Apoptosis-inducing effects and growth inhibitory of a novel chalcone, in human hepatic cancer cells and lung cancer cells
Dong Naiwei, Xin Liu, Tong Zhao, Lei Wang, Huimin Li, Shuqian Zhang, Xia Li, Xue Bai, Yong Zhang, Baofeng Yang> ;Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2018 Sep 1
16 citations
Comparison of immunogenicity, efficacy and transcriptome changes of inactivated rabies virus vaccine with different adjuvants.
Wei Shi, Yiming Kou, Jinghui Xiao, Lijuan Zhang, Feng Gao, Wei Kong, Weiheng Su, Chunlai Jiang, Yong Zhang> ;Vaccine. 2018 Aug 9
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Lectures

FoMyo5 Motor Domain Substitutions (Val151 to Ala and Ser418 to Thr) Cause Natural Resistance to Fungicide Phenamacril in Fusarium Oxysporum
Baton Rouge, LA - 6/14/2014

Press Mentions

Integrated Genomic and Transcriptomic Analysis Revealed Mutation Patterns of De-Differentiated Liposarcoma and LeiomyosarcomaOctober 28th, 2020
Islr Regulates Canonical Wnt Signaling-Mediated Skeletal Muscle Regeneration by Stabilizing Dishevelled-2 and Preventing AutophagyDecember 3rd, 2018
Damping of Selectively Bonded 3D Woven Lattice MaterialsOctober 2nd, 2018
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