YongZhaoMD

Blood Banking & Transfusion Medicine, Molecular Genetics, Transplantation Immunology, Clinical Pathology

Associate Professor, Transfusion Medicine and Pathology, University of Massachusetts Chan School of Medicine, Worcester, MA

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Office
55 Lake Ave N
Worcester, MA 01655
Phone+1 508-421-1950

Fax+1 302-737-5407
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Education & Training

Virginia Commonwealth University Health SystemFellowship, Molecular Genetic Pathology, 2003 - 2004
University of Iowa Hospitals and ClinicsFellowship, Blood Banking/Transfusion Medicine, 2002 - 2003
Vanderbilt University Medical CenterResidency, Pathology-Anatomic and Clinical, 1998 - 2002
OtherClass of 1982

Certifications & Licensure

MA State Medical License 2014 - 2026
PA State Medical License 2014 - 2016
DE State Medical License 2004 - 2015
MD State Medical License 2003 - 2015
IA State Medical License 2002 - 2004
TN State Medical License 2002 - 2004
American Board of Pathology Clinical Pathology
American Board of Pathology Blood Banking/Transfusion Medicine

Clinical Trials

Reversal of Type 1 Diabetes in Children by Stem Cell Educator Therapy Start of enrollment: 2013 Nov 01
Recruiting
Phase 1, Phase 2
Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes Start of enrollment: 2022 Sep 20
Recruiting
Phase 2, Phase 3

Publications & Presentations

PubMed

2 citations
Optimization of infusional calcium gluconate for prevention of hypocalcemic reactions during therapeutic plasma exchange
Yong Zhao, Danielle Garrity, Molly Graves, Jeanne Linden, Patricia St. Pierre, Paula Ducharme, Mindy Greene, Michelle Vauthrin, Robert Weinstein> ;Journal of Clinical Apheresis. 2019 Dec 1
3 citations
Performance characteristics of the PowerFlow apheresis port: Early experience.
Danielle Garrity, Molly Graves, Jeanne Linden, Patricia St. Pierre, Paula Ducharme, Yong Zhao, Mindy Greene, Michelle Vauthrin, Robert Weinstein> ;Journal of Clinical Apheresis. 2019 Aug 19
The apheresis management of patients undergoing transplantation: a concise review
Sierra C. Simmons, Jill Adamski, Mary Berg, Elizabeth Biller, Deanna C. Fang, Tina S. Ipe, Sara M. Shunkwiler, Yong Zhao, Beverly W. Baron, Huy P. Pham> ;Transfusion. 2019 May 1
7 citations
Prophylactic infusion of calcium gluconate to prevent a symptomatic fall in plasma ionized calcium during therapeutic plasma exchange: A comparison of two methods.
Yong Zhao, Jeanne Linden, Linda Welch, Patricia St. Pierre, Molly Graves, Danielle Garrity, Paula Ducharme, Jeffrey A. Bailey, Mindy Greene, Michelle Vauthrin, Robert ...> ;Journal of Clinical Apheresis. 2018 Oct 1
29 citations
Red blood cell exchange in patients with sickle cell disease-indications and management: a review and consensus report by the therapeutic apheresis subsection of the A...
Elizabeth Biller, Yong Zhao, Mary Berg, Lisa N. Boggio, Kelley E. Capocelli, Deanna C. Fang, Scott A. Koepsell, Lejla Music-Aplenc, Huy P. Pham, Angela Treml, John Wei...> ;Transfusion. 2018 Aug 1
2 citations
Dietary citrate and plasma ionized calcium: Implications for platelet donors.
Stefanie Haynes, Elda Hickson, Jeanne Linden, Patricia St. Pierre, Paula Ducharme, Paula Sulmasy, Linda Welch, Yong Zhao, Mindy Greene, Michelle Vauthrin, Robert Weins...> ;Journal of Clinical Apheresis. 2018 Jun 1
2 citations
Automated red blood cell exchange in preparation for filgrastim mobilization of autologous peripheral blood hematopoietic progenitor cells in a patient with sickle cel...
Yong Zhao, Jeffrey A. Bailey, Jeanne Linden, Patricia St. Pierre, Jan Cerny, Michelle Vauthrin, Mindy Greene, Robert Weinstein> ;Journal of Clinical Apheresis. 2018 Jun 1
7 citations
A liquid calcium+vitamin D3 supplement is effective prophylaxis against hypocalcemic toxicity during apheresis platelet donation.
Robert Weinstein, Stefanie Haynes, Yong Zhao, Elda Hickson, Jeanne Linden, Patricia St. Pierre, Paula Ducharme, Paula Sulmasy, Molly Graves, Jeffrey A. Bailey, Linda W...> ;Journal of Clinical Apheresis. 2018 Feb 1
40 citations
The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3
Chunmei Wang, Qinlan Wang, Xiaoqing Xu, Bin Xie, Yong Zhao, Nan Li, Xuetao Cao> ;The Journal of Experimental Medicine. 2017 Dec 4
3 citations
Therapeutic apheresis using a mononuclear cell program to lower the microfilaria burden of a 23‐year‐old African woman with loiasis
Yong Zhao, Brian Alexander, Jeffrey A. Bailey, Linda Welch, Mindy Greene, Michelle Vauthrin, Michael E. Mitchell, Robert Weinstein> ;Journal of Clinical Apheresis. 2017 Jun 1
4 citations
Therapeutic plasma exchange performed in tandem with hemodialysis without supplemental calcium in the apheresis circuit
Yong Zhao, Hiba Ibrahim, Jeffrey A. Bailey, Jeanne Linden, Elda Hickson, Stefanie Haynes, Mindy Greene, Michelle Vauthrin, Robert Weinstein> ;Journal of Clinical Apheresis. 2017 Jun 1
94 citations
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration
Xuxu Sun, Jen Chieh Chuang, Mohammed Kanchwala, Linwei Wu, Cemre Celen, Lin Li, Hanquan Liang, Shuyuan Zhang, Thomas Maples, Liem H. Nguyen, Sam C. Wang, Robert A.J. S...> ;Cell Stem Cell. 2016 Apr 7
Structural evolution and mechanical behaviour of Pt nanoparticle superlattices at high pressure.
Zhu, J.,Quan, Z.,Wang, C.,Wen, X.,Jiang, Y.,Fang, J.,Wang, Z.,Zhao, Y.,Xu, H.> ;Nanoscale. 2016 Feb 18
5 citations
Increased monocytes and bands following a red blood cell transfusion.
A M Ellefson, Robert Locke, Yong Zhao, Amy Mackley, David A. Paul> ;Journal of Perinatology. 2016 Jan 1
37 citations
GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions.
Judith Agudo, Albert Ruzo, Eun Sook Park, Robert Sweeney, Veronika Kana, Meng Wu, Yong Zhao, Dieter Egli, Miriam Merad, Brian D. Brown> ;Nature Biotechnology. 2015 Dec 1
33 citations
Modulation of Autoimmune T-Cell Memory by Stem Cell Educator Therapy: Phase 1/2 Clinical Trial
Elías Delgado, Marcos Perez-Basterrechea, Beatriz Suarez-Alvarez, Huimin Zhou, Eva Martinez Revuelta, Jose Maria Garcia-Gala, Silvia Pérez, María Álvarez-Viejo, Edelmi...> ;Ebiomedicine. 2015 Dec 1
31 citations
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient
Xiaowen Liu, Tao Yang, Koya Suzuki, Sachiko Tsukita, Masaru Ishii, Shuping Zhou, Gang Wang, Luyang Cao, Feng Qian, Shalina Taylor, Myung-Jin Oh, Irena Levitan, Richard...> ;The Journal of Experimental Medicine. 2015 Feb 9
27 citations
Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5 -directed contractile cardiomyocyte program in the sinoatrial node
Meng Wu, Siwu Peng, Jialiang Yang, Zhidong Tu, Xiaoqiang Cai, Chen-Leng Cai, Zhong Wang, Yong Zhao> ;Cell Research. 2014 Aug 22
37 citations
Identification and Purification of Human Induced Pluripotent Stem Cell-Derived Atrial-Like Cardiomyocytes Based on Sarcolipin Expression
Rebecca Josowitz, Jia Lu, Christine Falce, Sunita L. D’Souza, Meng Wu, Ninette Cohen, Nicole Dubois, Yong Zhao, Eric A. Sobie, Glenn I. Fishman, Bruce D. Gelb> ;Plos One. 2014 Jul 10
12 citations
Inducible gene deletion in the entire cardiac conduction system using Hcn4-CreERT2 BAC transgenic mice.
Meng Wu, Siwu Peng, Yong Zhao> ;Genesis. 2014 Feb 1
52 citations
Multifaceted roles of miR-1s in repressing the fetal gene program in the heart.
Yu-Sheng Wei, Siwu Peng, Meng Wu, Ravi Sachidanandam, Zhidong Tu, Shihong Zhang, Christine Falce, Eric A. Sobie, Djamel Lebeche, Yong Zhao> ;Cell Research. 2014 Jan 31
Mechanical comparison between lengthened and short sacroiliac screws in sacral fracture fixation: a finite element analysis.
Zhao, Y.,Zhang, S.,Sun, T.,Wang, D.,Lian, W.,Tan, J.,Zou, D.,Zhao, Y.> ;Orthop Traumatol Surg Res. 2013 Jul 16
66 citations
Receptor for Advanced Glycation End Products (RAGE) on iNKT Cells Mediates Lung Ischemia–Reperfusion Injury
Ashish Sharma, Damien J. LaPar, Matthew L. Stone, Yunge Zhao, Irving L. Kron, Victor E. Laubach> ;American Journal of Transplantation. 2013 Sep 1
60 citations
Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II c...
Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Huimin Zhou, Zhaohui Yin, Yana Chen, Ye Zhang, Shanfeng Wang, Jie Shen, Hatim Thaker, Summit Jain, ...> ;BMC Medicine. 2013 Jul 9
23 citations
Stem Cell Educator Therapy and Induction of Immune Balance
Yong Zhao> ;Current Diabetes Reports. 2012 Jul 26
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Journal Articles

Red Blood Cell Exchange in Patients with Sickle Cell Disease—Indications and Management: A Review and Consensus Report by the Therapeutic Apheresis Subsection of the AABB
Mary Berg, Scott Koepsell, Angela Treml, Kelley E Capocelli, John Weiss, Geoffrey Wool, Beverly W Baron, Yong Zhao, Lisa Boggio, Elizabeth Biller, Huy P Pham, Transfusion

Press Mentions

Lessons of an Adult StudentJune 29th, 2021
Build Back Better: Avoid the Learning Loss TrapMarch 4th, 2021
A Next-Generation Tumor-Targeting IL-2 Preferentially Promotes Tumor-Infiltrating CD8+ T-cell Response and Effective Tumor ControlAugust 28th, 2020
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Hospital Affiliations

UMass Memorial Medical CenterWorcester, Massachusetts