Yoon-JaeChoMD

Child Neurology • Portland, OR

Ericksen Family Endowed Professor for Research, Chief of Pediatric Neurology, Department of Pediatrics, OHSU

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Office
707 SW Gaines St
CDRC-P
Portland, OR 97239
Phone+1 503-494-9113
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Education & Training

Children's Hospital/Beth Israel Deaconess Medical Center/Harvard Medical SchoolFellowship, Child Neurology, 2004 - 2007
Children's Hospital-OaklandResidency, Pediatrics, 2003 - 2004
UPMC Medical EducationInternship, Transitional Year, 2002 - 2003
Oregon Health and Science University School of MedicineClass of 2002

Certifications & Licensure

CA State Medical License 2011 - Present
OR State Medical License 2016 - 2025
MA State Medical License 2007 - 2012
PA State Medical License 2002 - 2003
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology

Publications & Presentations

PubMed

1 citations
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.
Rich, J., Owen S Chapman, Jens Luebeck, Sunita Sridhar, Ivy Tsz-Lo Wong, Deobrat Dixit, Shanqing Wang, Gino Prasad, Utkrisht Rajkumar, Meghana S Pagadala, Jon D Larson...> ;Nature Genetics. 2023 Dec 1
23 citations
MRI Radiogenomics of Pediatric Medulloblastoma: A Multicenter Study.
Michael Zhang, Samuel W Wong, Jason N Wright, Matthias W Wagner, Sebastian Toescu, Michelle Han, Lydia T Tam, Quan Zhou, Saman S Ahmadian, Katie Shpanskaya, Seth Lummu...> ;Radiology. 2022 Aug 1
7 citations
AAV-vector based gene therapy for mitochondrial disease: progress and future perspectives.
Allison R Hanaford, Yoon-Jae Cho, Hiroyuki Nakai> ;Orphanet Journal of Rare Diseases. 2022 Jun 6
8 citations
Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers Exhibiting Hypermutation: An IRRDC Study.
Jacob J Henderson, Anirban Das, Daniel A Morgenstern, Sumedha Sudhaman, Vanessa Bianchi, Jill Chung, Logine Negm, Melissa Edwards, David E Kram, Michael Osborn, Cynthi...> ;JCO Precision Oncology. 2022 Mar 1
Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.
Alexandra Garancher, Hiromichi Suzuki, Svasti Haricharan, Lianne Q Chau, Meher Beigi Masihi, Jessica M Rusert, Paula S Norris, Florent Carrette, Megan M Romero, Sorana...> ;Nature Neuroscience. 2022 Jan 1
8 citations
Mechanisms of targeted therapy resistance in a pediatric glioma driven by ETV6-NTRK3 fusion.
Clare Keddy, Tanaya Neff, Jianya Huan, Joshua P. Nickerson, Catherine Z. Beach, Yassmine Akkari, Jianling Ji, Stephen Moore, Kellie J. Nazemi, Christopher L. Corless, ...> ;Cold Spring Harbor Molecular Case Studies. 2021 Oct 1
27 citations
Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma
Rahul Kumar, Kyle S. Smith, Maximilian Deng, Colt Terhune, Giles W. Robinson, Brent A. Orr, Anthony P. Y. Liu, Tong Lin, Catherine A. Billups, Murali Chintagumpala, Da...> ;Journal of Clinical Oncology. 2021 Jan 27
28 citations
Functional precision medicine identifies new therapeutic candidates for medulloblastoma
Jessica M. Rusert, Edwin F. Juarez, Sebastian Brabetz, James Jensen, Alexandra Garancher, Lianne Q. Chau, Silvia K. Tacheva-Grigorova, Sameerah Wahab, Yoko T. Udaka, D...> ;Cancer Research. 2020 Dec 1
33 citations
Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma
Alexandra Garancher, Hiromichi Suzuki, Svasti Haricharan, Lianne Q. Chau, Meher Beigi Masihi, Jessica M. Rusert, Paula S. Norris, Florent Carrette, Megan M. Romero, So...> ;Nature Neuroscience. 2020 May 18
2 citations
Correction: Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide.
Ryan T. Nitta, Sara Bolin, Emily Luo, David E. Solow-Cordero, Peyman Samghabadi, Teresa Purzner, Parvir S. Aujla, Ginikachi Nwagbo, Yoon Jae Cho, Gordon Li> ;Oncogene. 2020 Feb 1
3 citations
Measure Twice: Promise of Liquid Biopsy in Pediatric High-Grade Gliomas.
Matthew S. Dietz, Catherine Z. Beach, Ramon F. Barajas, Michael S. Parappilly, Sidharth K. Sengupta, Lissa C. Baird, Jeremy N. Ciporen, Seunggu J. Han, Rebecca Loret D...> ;Advances in Radiation Oncology. 2020 Jan 28
17 citations
Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide
Ryan T. Nitta, Sara Bolin, Emily Luo, David E. Solow-Codero, Peyman Samghabadi, Teresa Purzner, Parvir S. Aujla, Ginikachi Nwagbo, Yoon Jae Cho, Gordon Li> ;Oncogene. 2019 Aug 12
48 citations
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.
Miller Huang, Jignesh Tailor, Qiqi Zhen, Aaron Gillmor, Matthew L. Miller, Holger Weishaupt, Justin Chen, Tina Zheng, Emily K. Nash, Lauren K. McHenry, Z. H. An, Fubai...> ;Cell Stem Cell. 2019 Sep 5
15 citations
Col2-GFP reporter mouse--a new tool to study skeletal development.
Jae Y. Cho, T. Dawn Grant, G P Lunstrum, William A. Horton> ;American Journal of Medical Genetics. 2001 Dec 1
9 citations
Notes from the Field: Tetanus in an Unvaccinated Child - Oregon, 2017.
Judith A. Guzman-Cottrill, Christina Lancioni, Carl Eriksson, Yoon Jae Cho, Juventila Liko> ;MMWR. Morbidity and Mortality Weekly Report. 2019 Mar 8
22 citations
BMI1 is a therapeutic target in recurrent medulloblastoma
David Bakhshinyan, Chitra Venugopal, Ashley A. Adile, Neha Garg, Branavan Manoranjan, Robin M. Hallett, Xin Wang, Sujeivan Mahendram, Parvez Vora, Thusyanth Vijayakuma...> ;Oncogene. 2019 Mar 1
68 citations
MR Imaging-Based Radiomic Signatures of Distinct Molecular Subgroups of Medulloblastoma.
Mu Zhou, Katie Shpanskaya, Sébastien Perreault, Zichen Wang, Eric Tranvinh, Bryan Lanzman, Sridhar Vajapeyam, Nicholas A Vitanza, Paul G. Fisher, Yoon Jae Cho, Suzanne...> ;AJNR. American Journal of Neuroradiology. 2019 Jan 1
2 citations
Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma.
Suzana Assad Kahn, Xin Wang, Ryan T. Nitta, Sharareh Gholamin, Johanna Theruvath, Gregor Hutter, Tej D. Azad, Lina Wadi, Sara Bolin, Vijay Ramaswamy, Rogelio Esparza, ...> ;Nature Communications. 2018 Nov 2
31 citations
Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma
Suzana Assad Kahn, Xin Wang, Ryan T. Nitta, Sharareh Gholamin, Johanna Theruvath, Gregor Hutter, Tej D. Azad, Lina Wadi, Sara Bolin, Vijay Ramaswamy, Rogelio Esparza, ...> ;Nature Communications. 2018 Oct 8
48 citations
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma
Teresa Purzner, James Purzner, Taylor Buckstaff, Giorgio Cozza, Sharareh Gholamin, Jessica M. Rusert, Tom A. Hartl, John L. Sanders, Nicholas R. Conley, Xuecai Ge, Mar...> ;Science Signaling. 2018 Sep 11
27 citations
Erratum: A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases (S0092867418301156 (2018) 172(5) (1050–1062.e14) (S0092867418301156) (10.1016/j.cell.2018.0...
Livia Garzia, Noriyuki Kijima, A. Sorana Morrissy, Pasqualino De Antonellis, Ana Guerreiro-Stucklin, Borja L. Holgado, Xiaochong Wu, Xin Wang, Michael J. Parsons, Kory...> ;Cell. 2018 May 31
62 citations
Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma
Sara Bolin, Anna Borgenvik, Camilla U. Persson, Anders Sundström, Jun Qi, James E. Bradner, William A. Weiss, Yoon Jae Cho, Holger Weishaupt, Fredrik J. Swartling> ;Oncogene. 2018 Mar 7
26 citations
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.
Livia Garzia, Noriyuki Kijima, A Sorana Morrissy, Pasqualino De Antonellis, Ana Guerreiro-Stucklin, Borja L Holgado, Xiaochong Wu, Xin Wang, Michael Parsons, Kory Zayn...> ;Cell. 2018 Feb 22
51 citations
A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer
Zachary A. Yochum, Jessica Cades, Lucia Mazzacurati, Neil M. Neumann, Susheel K. Khetarpal, Suman Chatterjee, Hailun Wang, Myriam A. Attar, Eric H.-B. Huang, Sarah N. ...> ;Molecular Cancer Research. 2017 Dec 1
656 citations
The whole-genome landscape of medulloblastoma subtypes
Paul A. Northcott, Ivo Buchhalter, A. Sorana Morrissy, Volker Hovestadt, Joachim Weischenfeldt, Tobias Ehrenberger, Susanne Gröbner, Maia Segura-Wang, Thomas Zichner, ...> ;Nature. 2017 Jul 19
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Press Mentions

Genetic Mutations That Cause Common Childhood Brain Tumors IdentifiedJuly 22nd, 2012
Tumor Microvesicles Reveal Detailed Genetic InformationFebruary 10th, 2011