Yu-MinPaulShenMDFACP(He/Him)

Clotting Disorder, Hemophilia & Bleeding Disorder

Professor, Internal Medicine, University of Texas Southwestern Medical Center, Southwestern Medical School Medical Director, North Texas Comprehensive Hemophilia Treatment Center Adult Program

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Office
5323 Harry Hines Boulevard
Dallas, TX 75390
Phone+1 214-645-2800

Fax+1 214-645-2836
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Education & Training

University of Texas Southwestern Medical CenterFellowship, Hematology and Medical Oncology, 2001 - 2004
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1995 - 1998
University of California San Diego School of MedicineClass of 1995

Certifications & Licensure

TX State Medical License 1997 - 2026
American Board of Internal Medicine Hematology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012

Clinical Trials

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis Start of enrollment: 2009 Nov 01
Completed
Phase 3

Publications & Presentations

PubMed

3 citations
Bortezomib in relapsed/refractory immune thrombotic thrombocytopenic purpura: A single-centre retrospective cohort and systematic literature review.
Nicholas C J Lee, Sean Yates, Siayareh Rambally, Ravi Sarode, Ibrahim F Ibrahim, Yu-Min Shen, Sandra L Hofmann, Natalie R Bavli> ;British Journal of Haematology. 2024 Feb 1
2 citations
Phase II trials of zilucoplan in paroxysmal nocturnal hemoglobinuria.
Austin G Kulasekararaj, Anna-Elina Lehtinen, Cecily Forsyth, Shreyans Gandhi, Morag Griffin, Sixten Körper, Gabor Mikala, Petra Muus, Ulrik Overgaard, Christopher J Pa...> ;Haematologica. 2024 Mar 1
1 citations
Successful use of lenalidomide to treat refractory acquired von Willebrand disease associated with monoclonal gammopathy.
Allen Green, Yu-Min P Shen, Andrew T Nelson, Ravi Sarode, Ibrahim F Ibrahim, Jing Cao, Sajjad Afraz, Sean G Yates> ;Annals of Hematology. 2022 Dec 1
2 citations
Utilization of emicizumab in acquired hemophilia A: A case report.
Sean G Yates, Christopher B Webb, Ravi Sarode, Ibrahim F Ibrahim, Yu-Min P Shen> ;Transfusion and Apheresis Science. 2022 Dec 1
Scurvy: a rare cause of haemarthrosis.
Patrick Marquardt, Ganesh Raman, Yu-Min Shen, David H Wang> ;BMJ Case Reports. 2022 Mar 7
8 citations
Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome
Haiyan Chu, Anastasia Sacharidou, An Nguyen, Chun Li, Ken L. Chambliss, Jane E. Salmon, Yu-min P Shen, Julie Lo, Gustavo Leone, Joachim Herz, David Y. Hui, Denise K. M...> ;Circulation Research. 2021 Sep 17
3 citations
Lymphomatoid granulomatosis of the central nervous system (CNS-LYG) posing a management challenge
Mohsin Soleja, Jesse Jaso, Weina Chen, Jack M Raisanen, Christian A. Wysocki, Yu Min Shen, Bruce E. Mickey, Kiran A Kumar, Praveen Ramakrishnan Geethakumari> ;Clinical Case Reports. 2021 Sep 1
6 citations
Comparison of Low Fixed Dose Versus Standard-Dose Rituximab to Treat Thrombotic Thrombocytopenic Purpura in the Acute Phase and Preemptively During Remission
Manasa Reddy, Sandra L. Hofmann, Yu-min P Shen, Srikanth Nagalla, Siayareh Rambally, Amena Usmani, Ravi Sarode> ;Transfusion and Apheresis Science. 2020 Jul 22
ORE Identifies Extreme Expression Effects Enriched for Rare Variants.
Richter, F.,Hoffman, G. E.,Manheimer, K. B.,Patel, N.,Sharp, A. J.,McKean, D.,Morton, S. U.,DePalma, S.,Gorham, J.,Kitaygorodksy, A.,Porter, G. A.,Giardini, A.,Shen, Y...> ;Bioinformatics. 2019 Mar 25
6 citations
Hypercoagulable Workup in Thrombotic Cardiovascular Diseases
Yu-min P Shen, Srikanth Nagalla> ;Circulation. 2018 Jul 17
2 citations
The Novel Protease-Activated Receptor 1 Antagonist Vorapaxar as a Treatment for Thrombosis in Afibrinogenemia.
Bernard Tawfik, Elizabeth Pollard, Yu-min P Shen> ;Seminars in Thrombosis and Hemostasis. 2018 May 15
41 citations
Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium.
Anastasia Sacharidou, Ken L. Chambliss, Victoria Ulrich, Jane E. Salmon, Yu-min P Shen, Joachim Herz, David Y. Hui, Lance S. Terada, Philip W. Shaul, Chieko Mineo> ;Blood. 2018 May 10
5 citations
Identifying Additional Risk Factors for Thrombosis and Pregnancy Morbidities Among Antiphospholipid Antibodies Carriers.
Yu Zuo, Jennifer Fan, Ravindra Sarode, Song Zhang, Una E. Makris, David R. Karp, Yu-min P Shen> ;Clinical and Applied Thrombosis/hemostasis. 2018 Feb 22
Evaluating Thrombocytopenia During Heparin Therapy
Yu-min P Shen, Heather R Wolfe, Stephen Barman> ;JAMA. 2018 Feb 6
Smad6 Methylation Represses NFκB Activation and Periodontal Inflammation.
Zhang, T.,Wu, J.,Ungvijanpunya, N.,Jackson-Weaver, O.,Gou, Y.,Feng, J.,Ho, T. V.,Shen, Y.,Liu, J.,Richard, S.,Jin, J.,Hajishengallis, G.,Chai, Y.,Xu, J.> ;J. Dent. Res.. 2018 Feb 09
2 citations
The role of cardiovascular disease risk assessed by ASCVD score in primary thrombosis prophylaxis strategy among antiphospholipid antibody carriers.
Yu Zuo, A. Udupa, J. Fan, Una E. Makris, David R. Karp, Yu-min P Shen> ;Lupus. 2018 Jan 1
6 citations
A case of autoimmune severe acquired von Willebrand syndrome (type 3-like).
Chakri Gavva, Prapti A. Patel, Yu-min P Shen, Eugene P. Frenkel, Ravindra Sarode> ;Transfusion and Apheresis Science. 2017 Jun 1
Coagulation Testing in a Bleeding Patient
Sung-hee Choi, Siayreh Rambally, Yu-min P Shen> ;JAMA. 2017 Apr 11
7 citations
Mixing Study for Evaluation of Abnormal Coagulation Testing.
Sung Hee Choi, Siayareh Rambally, Yu-min P Shen> ;JAMA. 2016 Nov 22
14 citations
Clinical evaluation of thrombotic microangiopathy: identification of patients with suspected atypical hemolytic uremic syndrome
Yu-min P Shen> ;Thrombosis Journal. 2016 Oct 4
15 citations
Can an anti-Xa assay for low-molecular-weight heparin be used to assess the presence of rivaroxaban?
Sean G. Yates, Sabra Smith, William Tharpe, Yu-min P Shen, Ravi Sarode> ;Transfusion and Apheresis Science. 2016 Oct 1
21 citations
Identification of a Monoclonal Antibody That Attenuates Antiphospholipid Syndrome-Related Pregnancy Complications and Thrombosis.
Chieko Mineo, Lane Lanier, Eunjeong Jung, Samarpita Sengupta, Victoria Ulrich, Anastasia Sacharidou, Cristina Tarango, Olutoye Osunbunmi, Yu-min P Shen, Jane E. Salmon...> ;Plos One. 2016 Jul 27
27 citations
Analysis of Thrombophilia Test Ordering Practices at an Academic Center: A Proposal for Appropriate Testing to Reduce Harm and Cost
Yu-min P Shen, Judy Peih Ying Tsai, Evelyn O. Taiwo, Chakri Gavva, Sean G. Yates, Vivek A. Patel, Eugene P. Frenkel, Ravi Sarode> ;Plos One. 2016 May 13
2 citations
Characteristics and Outcomes of Renal Transplant Recipients with Hemolytic Uremic Syndrome in the United States.
Bekir Tanriover, Ronak Lakhia, Yu-Min Shen, Burhaneddin Sandikci, Ramesh Saxena, Malcolm MacConmara, Abigail A. Soyombo, Nilum Rajora, Mark A. Hardy> ;Transplantation Direct. 2015 Nov 1
846 citations
Long-term safety and efficacy of factor IX gene therapy in hemophilia B
Amit C. Nathwani, Ulreke M Reiss, Edward G. D. Tuddenham, Cecilia Rosales, Pratima Chowdary, Jenny McIntosh, Marco Della Peruta, Elsa Lheriteau, Nishal Patel, Deepak R...> ;The New England Journal of Medicine. 2014 Nov 20
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