YuanbinChenMD

PubMed

• 2 citations
  Durvalumab ± Tremelimumab + Platinum-Etoposide in Extensive-Stage Small Cell Lung Cancer (CASPIAN): Outcomes by PD-L1 Expression and Tissue Tumor Mutational Burden.
  Paz-Ares, L., Garassino, M., Chen, Y., Reinmuth, N., Hotta, K., Poltoratskiy, A., Trukhin, D., Hochmair, M., Özgüroğlu, M., Ji, J., Statsenko, G., Conev, N., Bondarenk...> ;Clinical Cancer Research. 2024 Feb 16
• 117 citations
  Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma.
  Sapna P Patel, Megan Othus, Yuanbin Chen, G Paul Wright Jr, Kathleen J Yost, John R Hyngstrom, Siwen Hu-Lieskovan, Christopher D Lao, Leslie A Fecher, Thach-Giao Truon...> ;The New England Journal of Medicine. 2023 Mar 2
• Current and Emerging Treatment Options for Patients With Relapsed Small-cell Lung Carcinoma: A Systematic Literature Review.
  Reyes Bernabé-Caro, Yuanbin Chen, Afshin Dowlati, Paula Eason> ;Clinical Lung Cancer. 2023 May 1
• 66 citations
  Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASmutation: a randomised, open-label, phase 3 trial.
  Adrianus Johannes de Langen, Melissa L Johnson, Julien Mazieres, Anne-Marie C Dingemans, Giannis Mountzios, Miklos Pless, Jürgen Wolf, Martin Schuler, Hervé Lena, Ferd...> ;Lancet. 2023 Mar 4
• 11 citations
  Impact of Brain Metastases on Treatment Patterns and Outcomes With First-Line Durvalumab Plus Platinum-Etoposide in Extensive-Stage SCLC (CASPIAN): A Brief Report.
  Yuanbin Chen, Luis Paz-Ares, Niels Reinmuth, Marina Chiara Garassino, Galina Statsenko, Maximilian J Hochmair, Mustafa Özgüroğlu, Francesco Verderame, Libor Havel, Gyö...> ;JTO Clinical and Research Reports. 2022 Jun 1
• 5 citations
  RESILIENT part 1: a phase 2 dose-exploration and dose-expansion study of second-line liposomal irinotecan in adults with small cell lung cancer.
  Luis Paz-Ares, David R Spigel, Yuanbin Chen, Maria Jove, Oscar Juan-Vidal, Patricia Rich, Theresa Hayes, Vanesa Gutiérrez Calderón, Reyes Bernabe Caro, Alejandro Navar...> ;Cancer. 2022 May 1
• 25 citations
  Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models.
  Delphine Lissa, Nobuyuki Takahashi, Parth Desai, Irena Manukyan, Christopher W Schultz, Vinodh Rajapakse, Moises J Velez, Deborah Mulford, Nitin Roper, Samantha Nichol...> ;Nature Communications. 2022 Apr 19
• 275 citations
  Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CA...
  Jonathan W. Goldman, Mikhail Dvorkin, Y. Chen, Niels Reinmuth, Katsuyuki Hotta, D. Trukhin, Galina Statsenko, Maximilian J Hochmair, Mustafa Ozguroglu, J.H. Ji, Marina...> ;The Lancet. Oncology. 2021 Jan 1
• 19 citations
  Patient-reported outcomes with first-line durvalumab plus platinum-etoposide versus platinum-etoposide in extensive-stage small-cell lung cancer (CASPIAN): a randomize...
  Jonathan W. Goldman, Marina Chiara Garassino, Y. Chen, Mustafa Ozguroglu, Mikhail Dvorkin, D. Trukhin, Galina Statsenko, Katsuyuki Hotta, J.H. Ji, Maximilian Hochmair,...> ;Lung Cancer. 2020 Sep 10
• 33 citations
  Design and Rationale for a Phase III, Randomized, Placebo-controlled Trial of Durvalumab With or Without Tremelimumab After Concurrent Chemoradiotherapy for Patients W...
  Suresh Senan, Isamu Okamoto, Gyeong Won Lee, Yuanbin Chen, Seiji Niho, Gabriel Mak, Wenliang Yao, Norah J. Shire, H. Jiang, Byoung Chul Cho> ;Clinical Lung Cancer. 2020 Mar 1
• 986 citations
  Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, ope...
  Luis Paz-Ares, M. Dvorkin, Y. Chen, Niels Reinmuth, Katsuyuki Hotta, D. Trukhin, Galina Statsenko, Maximilian Hochmair, Mustafa Ozguroglu, J.H. Ji, Oleksandr Voitko, A...> ;Lancet. 2019 Nov 23
• 129 citations
  Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study
  Anish Thomas, Rasa Vilimas, Christopher Trindade, Rebecca A. Erwin-Cohen, Nitin Roper, Liqiang Xi, Venkatesh Krishnasamy, Elliot Levy, Andy Mammen, Samantha Nichols, Y...> ;Journal of Thoracic Oncology. 2019 Aug 1
• 6 citations
  Long non-coding RNA expression profiles reveals AK098783 is a biomarker to predict poor prognosis in patients with colorectal cancer.
  Wang Xiaoli, Fen Liu, Liu Xiaoyuan, Fang Wang, Xiaoyu Liao, Yuan Bin Chen, Yong Mao, Dong Hua, Xiaosong Ge> ;Japanese Journal of Clinical Oncology. 2018 May 1
• 14 citations
  Expression of mesothelin in thymic carcinoma and its potential therapeutic significance
  Anish Thomas, Yuanbin Chen, Arlene Berman, David S. Schrump, Giuseppe Giaccone, Ira Pastan, David Venzon, David J. Liewehr, Seth M. Steinberg, Markku Miettinen, Raffit...> ;Lung Cancer. 2016 Nov 1
• 30 citations
  Distinctive clinical characteristics of malignant mesothelioma in young patients
  Anish Thomas, Yuanbin Chen, Tinghui Yu, Ammara Gill, Vinay Prasad> ;Oncotarget. 2015 Jun 11
• 71 citations
  Trends and characteristics of young non-small cell lung cancer patients in the United States
  Anish Thomas, Yuanbin Chen, Tinghui Yu, Marko Jakopović, Giuseppe Giaccone> ;Frontiers in Oncology. 2015 May 26
• 20 citations
  Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma
  Neetu Kalra, Jingli Zhang, Anish Thomas, Liqiang Xi, Mitchell Cheung, Jacqueline Talarchek, Sandra Burkett, Maria Tsokos, Yuanbin Chen, Mark Raffeld, Markku Miettinen,...> ;BMC Cancer. 2015 May 8
• 62 citations
  High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis
  Anish Thomas, Yuanbin Chen, Seth M. Steinberg, Ji Luo, Svetlana Pack, Mark Raffeld, Zied Abdullaev, Christine Alewine, Arun Rajan, Giuseppe Giaccone, Ira Pastan, Markk...> ;Oncotarget. 2015 Apr 13
• 66 citations
  A Phase I/II Trial of Belinostat in Combination with Cisplatin, Doxorubicin, and Cyclophosphamide in Thymic Epithelial Tumors: A Clinical and Translational Study
  Anish Thomas, Arun Rajan, Eva Szabo, Yusuke Tomita, Corey A. Carter, Barbara Scepura, Ariel Lopez-Chavez, Min-Jung Lee, Christophe E. Redon, Ari Frosch, Cody J. Peer, ...> ;Clinical Cancer Research. 2014 Nov 1
• 9 citations
  Novel biologic therapies for thymic epithelial tumors.
  Yuanbin Chen, Helen Gharwan, Anish Thomas> ;Frontiers in Oncology. 2014 May 7
• 128 citations
  Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.
  S Eliasz, Shuang Liang, Yu Chen, M A De Marco, O Machek, Sylvia Skucha, Lucio Miele, Maurizio Bocchetta> ;Oncogene. 2010 Apr 29
• 38 citations
  Tumorigenic properties of alternative osteopontin isoforms in mesothelioma.
  Sergey Ivanov, Alla V. Ivanova, Chandra Goparaju, Yuanbin Chen, Amanda Beck, Harvey I. Pass> ;Biochemical and Biophysical Research Communications. 2009 May 8
• 86 citations
  Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway
  Irene Graziani, Sandra Eliasz, Melissa A. De Marco, Yuanbin Chen, Harvey I. Pass, Richard D. May, Peter Strack, Lucio Miele, Maurizio Bocchetta> ;Cancer Research. 2008 Dec 1
• 120 citations
  Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung
  Yuanbin Chen, Melissa A. De Marco, Irene Graziani, Adi F. Gazdar, Peter Strack, Lucio Miele, Maurizio Bocchetta> ;Cancer Research. 2007 Sep 1
• 211 citations
  TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis
  Haining Yang, Maurizio Bocchetta, Barbara Kroczynska, Amira G. Elmishad, Yuanbin Chen, Zemin Liu, Concetta Bubici, Brooke T. Mossman, Harvey I. Pass, Joseph R. Testa, ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2006 Jul 5
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