I received a BA in medieval literature from Brown University in 1981, and an MD from Cornell University Medical College in 1984. This was followed by surgical training at the New York Hospital/Cornell Medical Center and a surgical oncology fellowship at the Memorial Sloan-Kettering Cancer Center. For over twenty years, I was an attending surgeon at the Memorial Sloan-Kettering Cancer Center (MSKCC), where I held the Murray F. Brennan Chair in Surgery, and was a Professor of Surgery at Weill Cornell Medical College. Currently I am the Chairman of the Department of Surgery at the City of Hope Medical Center.
I am well known clinically for my extensive work in the field of liver and pancreatic surgery––especially for hepatocellular carcinoma, hepatic metastases from colorectal cancer, gallbladder cancer, and cholangiocarcinoma. I pioneered many surgical, laparoscopic, robotic and ablative therapies for these cancers.
I lead an active laboratory studying the use of genetically modified viruses for the killing of cancer. I was one of the first investigators to administer engineered viruses into the blood stream of humans for treatment of cancer. I have co-authored over 600 peer reviewed articles and 11 text books and have served on the editorial boards of 14 journals. Currently, I am Editor-in-Chief of Molecular Therapy Oncolytics (Nature Publishing).
Additionally I am a member of numerous scientific and medical societies including the American Surgical Association, Southern Surgical Association, and American Society for Clinical Investigation. I've received many honors and awards including the James IV Surgical Traveler, and the Shipley Award from the SSA. I've served on the board of the Society for Surgery of the Alimentary Tract and the board of the James IV Society of Surgeons. Additionally, I've been Chair of the Gastrointestinal Organ Site Committee of the ACSOG, and Chair of the recombinant DNA advisory committee of the National Institutes of Health.
Education & Training
Memorial Sloan-Kettering Cancer CenterFellowship, Surgical Oncology, 1991 - 1993
New York Presbyterian Hospital - Cornell CampusResidency, General Surgery, 1984 - 1991
New York Presbyterian Hospital - Cornell CampusFellowship, Nutrition Support Service, 1986 - 1989
Weill Cornell Medical College of Cornell UniversityClass of 1984
New York Presbyterian Hospital - Cornell CampusFellowship, Research Fellow, Department of Surgery
Certifications & Licensure
CA State Medical License2014 - 2021
NY State Medical License1985 - 2022
American Board of SurgerySurgery
Awards, Honors, & Recognition
America's Top DoctorsCastle Connolly, 2004-2014
Top Doctors: New York Metro AreaCastle Connolly, 2004-2014
America's Top Doctors for CancerCastle Connolly, 2005-2013
New York Magazine: Top DoctorsCastle Connolly, 2003-2013
Elected MemberThe American Society for Clinical Investigation, 2003
Melstrom, L. G., Eng, O. S., Raoof, M., Singh, G., Fong, Y., Latorre, K., Choi, G. H., Salem, R., Bentrem, D. J., Lewandowski, R., Makris, E., Poultsides, G., Dhar, V....> ;HPB : the official journal of the International Hepato Pancreato Biliary Association. 2019 Apr 22