Yvette I Sheline MD MS
Geriatric Psychiatry
McLure Endowed Professor, Department of Psychiatry and Radiology University of Pennsylvania and Director, Center for Neuromodulation in Depression and Stress (CNDS), University of Pennsylvania
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3700 Hamilton WalkRichards D307Philadelphia, PA 19104
Phone+1 215-573-0082
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Education & Training
Beth Israel Deaconess Medical CenterResidency, Psychiatry, 1980 - 1983
Boston University School of MedicineClass of 1979
Certifications & Licensure
CA State Medical License 1983 - Present
PA State Medical License 2013 - 2026
MO State Medical License 1991 - 2014
American Board of Psychiatry and Neurology Psychiatry
Clinical Trials
Publications & Presentations
PubMed
- Prospective Development of a Whole-Brain Connectivity and Electric Field-Guided Transcranial Magnetic Stimulation Atlas for Posttraumatic Stress Disorder Symptoms.Sneha Chandrashekar, Grant Brighter, Ivy Sun, Hannah Gura, Milan Patel
Biological Psychiatry Global Open Science. 2026-09-01 - Impact of Vagus Nerve Stimulation on Suicidal Ideation in Markedly Treatment-Resistant Major Depression: A RECOVER Study Report.Vasilis C Hristidis, Victoria De Leon, Andrew D Van Der Vaart, Harold A Sackeim, A John Rush
The Journal of Clinical Psychiatry. 2026-07-08 - HARMONY: A large-scale harmonized neuroimaging dataset for research on anxious misery disorders.Setthanan Jarukasemkit, Michael P Harms, Petra Lenzini, Andrew Chen, Matthew F Glasser
Biorxiv. 2026-07-01
Journal Articles
- Network Changes Associated with Transdiagnostic Depressive Symptom Improvement Following Cognitive Behavioral Therapy in MDD and PTSDYvette Sheline, MD, Nature
Press Mentions
Multiple Brain Profiles May Underlie the Same Depressive SymptomsJune 19th, 2025- Multiple Brain Profiles Underlie the Same Symptoms in DepressionJune 19th, 2025
- A Hard Reset on Electroconvulsive TherapyMay 22nd, 2025
Grant Support
- HCP-2.0: Ascertaining Network Mechanisms and Analytics of Emotional Dysfunction (HARMONY)UNIVERSITY OF PENNSYLVANIA2023–2028
- HCP-2.0: Ascertaining Network Mechanisms and Analytics of Emotional Dysfunction (HARMONY)UNIVERSITY OF PENNSYLVANIA2023–2028
- Reducing neural perseveration through closed loop real time fMRI neurofeedback to alleviate depressive symptomsUNIVERSITY OF PENNSYLVANIA2021–2028
- 3/4-Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)UNIVERSITY OF PENNSYLVANIA2022–2027
- Reducing neural perseveration through closed loop real time fMRI neurofeedback to alleviate depressive symptomsUNIVERSITY OF PENNSYLVANIA2021–2025
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