ZacharyDaleGoodmanMD

PubMed

• 4 citations
  PRIMIS: design of a pivotal, randomized, phase 3 study evaluating the safety and efficacy of the nonsteroidal farnesoid X receptor agonist cilofexor in noncirrhotic pa...
  Michael Trauner, Chuhan Chung, Kate Sterling, Xiangyu Liu, Xiaomin Lu, Jun Xu, Clare Tempany-Afdhal, Zachary D Goodman, Martti Färkkilä, Atsushi Tanaka, Palak Trivedi,...> ;BMC Gastroenterology. 2023 Mar 15
• 56 citations
  Complexity of ballooned hepatocyte feature recognition: Defining a training atlas for artificial intelligence-based imaging in NAFLD.
  Elizabeth M Brunt, Andrew D Clouston, Zachary Goodman, Cynthia Guy, David E Kleiner, Carolin Lackner, Dina G Tiniakos, Aileen Wee, Matthew Yeh, Wei Qiang Leow, Elaine ...> ;Journal of Hepatology. 2022 May 1
• 39 citations
  Cirrhosis Regression is Associated with Improved Clinical Outcomes in Patients with Nonalcoholic Steatohepatitis.
  Arun J. Sanyal, Quentin M. Anstee, Michael Trauner, Eric Lawitz, Manal F. Abdelmalek, D. Ding, Ling Han, Catherine Jia, Ryan S Huss, Chuhan Chung, Vincent Wai-Sun Wong...> ;Hepatology. 2021 Oct 18
• 29 citations
  BMS-986263 in Patients with Advanced Hepatic Fibrosis: 36-Week Results from a Randomized, Placebo-Controlled Phase 2 Trial
  Eric Lawitz, Diane E. Shevell, Giridhar S. Tirucherai, Shuyan Du, Warner Chen, Uma Kavita, Angie Coste, Fred Poordad, Morten A. Karsdal, Mette Juul Nielsen, Zachary Go...> ;Hepatology. 2021 Oct 4
• 25 citations
  Comparison of ADAPT, FIB-4 and APRI as non-invasive predictors of liver fibrosis and NASH within the CENTAUR screening population.
  Mette Juul Nielsen, Diana Julie Leeming, Zachary Goodman, Scott L. Friedman, Peder Frederiksen, Daniel Guldager Kring Rasmussen, Pamela Vig, Star Seyedkazemi, Laurent ...> ;Journal of Hepatology. 2021 Aug 26
• 18 citations
  A Machine Learning Approach to Liver Histological Evaluation Predicts Clinically Significant Portal Hypertension in NASH Cirrhosis
  Jaime Bosch, Chuhan Chung, Oscar Carrasco-Zevallos, Stephen A. Harrison, Manal F. Abdelmalek, Mitchell L. Shiffman, Don C. Rockey, Zahil Shanis, Dinkar Juyal, Harsha P...> ;Hepatology. 2021 Aug 1
• 23 citations
  Inter- and Intra-individual Variation, and Limited Prognostic Utility, of Serum Alkaline Phosphatase in a Trial of Patients With Primary Sclerosing Cholangitis
  Palak J. Trivedi, Andrew J. Muir, Cynthia Levy, Christopher L. Bowlus, Michael P. Manns, Xiaomin Lu, Gerald Crans, Chuhan Chung, G. Mani Subramanian, Robert P. Myers, ...> ;Clinical Gastroenterology and Hepatology. 2021 Jun 1
• 13 citations
  Improvements of Fibrosis and Disease Activity Are Associated With Improvement of Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steat...
  Zobair M. Younossi, Maria Stepanova, Mazen Noureddin, Kris V. Kowdley, Simone I. Strasser, Anita Kohli, Peter Ruane, Mitchell L. Shiffman, Aasim Sheikh, Nadege Gunn, S...> ;Hepatology Communications. 2021 May 12
• 9 citations
  A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis.
  Yevgeniy Gindin, Chuhan Chung, Zhaoshi Jiang, Jing Zhu Zhou, Jun Xu, Andrew N. Billin, Robert P. Myers, Zachary Goodman, Abdolabdolamir Landi, Michael Houghton, Richar...> ;Hepatology. 2021 Mar 1
• 224 citations
  From NAFLD to MAFLD: Implications of a Premature Change in Terminology.
  Zobair M. Younossi, Mary E. Rinella, Arun J. Sanyal, Stephen A. Harrison, Elizabeth M. Brunt, Zachary Goodman, David E. Cohen, Rohit Loomba> ;Hepatology. 2021 Mar 1
• 32 citations
  The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients wi...
  Manal F. Abdelmalek, Edgar D. Charles, Arun J. Sanyal, Stephen A. Harrison, Brent A. Neuschwander-Tetri, Zachary Goodman, Richard A. Ehman, Morten A. Karsdal, Atsushi ...> ;Contemporary Clinical Trials. 2021 Feb 28
• 12 citations
  Performance of Noninvasive Liver Fibrosis Tests in Morbidly Obese Patients with Nonalcoholic Fatty Liver Disease.
  Saleh A. Alqahtani, Pegah Golabi, James Paik, Brian Lam, Amir H. Moazez, Hazem Elariny, Zachary Goodman, Zobair M. Younossi> ;Obesity Surgery. 2021 Feb 22
• 70 citations
  A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH.
  Amaro Taylor-Weiner, Harsha Pokkalla, Ling Han, Catherine Jia, Ryan S Huss, Chuhan Chung, Hunter L. Elliott, Benjamin Glass, Kishalve Pethia, Oscar Carrasco-Zevallos, ...> ;Hepatology. 2021 Feb 11
• 134 citations
  Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH
  Rohit Loomba, Mazen Noureddin, Kris V. Kowdley, Anita Kohli, Aasim Sheikh, Guy Neff, Bal R. Bhandari, Nadege Gunn, Stephen H. Caldwell, Zachary Goodman, Ilan Wapinski,...> ;Hepatology. 2021 Feb 1
• Fifty years of impact on liver pathology: a history of the Gnomes
  Michael Torbenson, Valeer Desmet, Helmut Denk, Francesco Callea, Alastair D. Burt, Stefan G. Hubscher, Luigi Terracciano, Hans Peter Dienes, Zachary Goodman, Pierre Be...> ;Virchows Archiv. 2021 Feb 1
• 5 citations
  Major Histocompatibility Complex Class I‐Related Chain A Alleles and Histology of Nonalcoholic Fatty Liver Disease
  Azza Karrar, Bijal Rajput, Siddharth Hariharan, Dinan Abdelatif, Mohamad Houry, Ali Moosvi, Irfan Ali, Daisong Tan, Sohailla Noor, Donna Esmaeili, Sean Felix, Lakshmi ...> ;Hepatology Communications. 2021 Jan 1
• 7 citations
  Multicenter, Double‐Blind, Randomized Trial of Emricasan in Hepatitis C–Treated Liver Transplant Recipients With Residual Fibrosis or Cirrhosis
  Ethan M. Weinberg, Michael P. Curry, Catherine Frenette, Fredric G. Regenstein, Eugene R. Schiff, Zachary Goodman, James M. Robinson, Jean L. Chan, Joanne C. Imperial,...> ;Liver Transplantation. 2020 Dec 29
• 191 citations
  Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study.
  Vlad Ratziu, Arun J. Sanyal, Stephen A. Harrison, Vincent Wai-Sun Wong, Sven Francque, Zachary Goodman, Guruprasad P. Aithal, Kris V. Kowdley, Star Seyedkazemi, Lauren...> ;Hepatology. 2020 Sep 1
• 28 citations
  Fatigue and Pruritus in Patients with Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: The Impact on Patient-Reported Outcomes
  Zobair M. Younossi, Vincent Wai-Sun Wong, Quentin M. Anstee, Manuel Romero-Gómez, M. Trauner, Stephen A. Harrison, Eric Lawitz, Takeshi Okanoue, Marianne Camargo, Kath...> ;Hepatology Communications. 2020 Aug 28
• 51 citations
  Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH.
  Davide Povero, Hirokazu Yamashita, Wenhua Ren, Mani Subramanian, Robert P. Myers, Akiko Eguchi, Douglas A. Simonetto, Zachary Goodman, Stephen A. Harrison, Arun J. San...> ;Hepatology Communications. 2020 Jul 3
• 238 citations
  Selonsertib for patients with bridging fibrosis or compensated cirrhosis due to NASH: Results from randomized phase III STELLAR trials
  Stephen A. Harrison, Vincent Wai-Sun Wong, Takeshi Okanoue, Natalie Bzowej, Raj Vuppalanchi, Ziad Younes, Anita Kohli, Shiv Kumar Sarin, Stephen H. Caldwell, Naim Alkh...> ;Journal of Hepatology. 2020 Jul 1
• 139 citations
  A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis.
  Stephen A. Harrison, Zachary Goodman, Abdul Jabbar, Ravi Vemulapalli, Ziad Younes, Bradley Freilich, Muhammad Y. Sheikh, Jörn M. Schattenberg, Zeid Kayali, Adam Zivony...> ;Journal of Hepatology. 2020 May 1
• 169 citations
  Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension
  Naga Chalasani, M. Abdelmalek, Guadalupe Garcia-Tsao, Raj Vuppalanchi, Naim Alkhouri, Mary E. Rinella, Mazen Noureddin, Maxmillan Pyko, Mitchell L. Shiffman, Arun J. S...> ;Gastroenterology. 2020 Apr 1
• Association of novel markers of liver disease with neonatal liver disease in premature baboons, Papio sp.
  Laura M. Keller, Stephanie Eighmy, Cun Li, Lauryn A. Winter, Jay Kerecman, Zachary Goodman, Naveen Mittal, Cynthia L. Blanco> ;Plos One. 2020 Mar 9
• 9 citations
  Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.
  Michael Trauner, Yevgeniy Gindin, Zhaoshi Jiang, Chuhan Chung, G. Mani Subramanian, Robert P. Myers, Aliya Gulamhusein, Kris V. Kowdley, Cynthia Levy, Zachary Goodman,...> ;JHEP Reports. 2020 Feb 1
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Journal Articles

• An Exploratory Study Examining How Nano-Liquid Chromatography–Mass Spectrometry and Phosphoproteomics Can Differentiate Patients with Advanced Fibrosis and Higher Perc...  
  Zobair M Younossi, Zachary D Goodman, BioMed Central