ZacharyAdamKohutekMD

PubMed

• 3 citations
  Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial.
  Erin F Gillespie, Joanna C Yang, Noah J Mathis, Catherine B Marine, Charlie White, Zhigang Zhang, Christopher A Barker, Rupesh Kotecha, Alyson McIntosh, Max Vaynrub, M...> ;Journal of Clinical Oncology. 2024 Jan 1
• 4 citations
  Should Postoperative Radiation for Long Bone Metastases Cover Part or All of the Orthopedic Hardware? Results of a Large Retrospective Analysis.
  Daniel B. Rosen, Justin M. Haseltine, Meredith K. Bartelstein, Jessica Flynn, Zhigang Zhang, Zachary A. Kohutek, Yoshiya Yamada, Adam Schmitt, Daniel S. Higginson, Mak...> ;Advances in Radiation Oncology. 2021 Jul 28
• 6 citations
  The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas.
  Alvin Makohon-Moore, Evan J. Lipson, Jody E. Hooper, Amanda Zucker, Jungeui Hong, Craig M. Bielski, Akimasa Hayashi, Collin Tokheim, Priscilla Baez, Rajya Kappagantula...> ;Clinical Cancer Research. 2021 Mar 1
• 11 citations
  18F-Fluorocholine PET uptake correlates with pathologic evidence of recurrent tumor after stereotactic radiosurgery for brain metastases.
  Milan Grkovski, Zachary A. Kohutek, Heiko Schöder, Cameron Brennan, Viviane Tabar, Philip H. Gutin, Zhigang Zhang, Robert J. Young, Bradley J. Beattie, Pat Zanzonico, ...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2020 Jun 1
• 99 citations
  A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma
  Akimasa Hayashi, Jun Fan, Ruoyao Chen, Yu-Jui Ho, Alvin Makohon-Moore, Nicolas Lecomte, Yi Zhong, Jungeui Hong, Jinlong Huang, Hitomi Sakamoto, Marc A. Attiyeh, Zachar...> ;Nature Cancer. 2020 Jan 13
• 179 citations
  Minimal functional driver gene heterogeneity among untreated metastases
  Johannes G. Reiter, Alvin Makohon-Moore, Jeffrey M. Gerold, Alexander Heyde, Marc A. Attiyeh, Zachary A. Kohutek, Collin Tokheim, Alexia Brown, Rayne M. DeBlasio, Juli...> ;Science. 2018 Sep 7
• 6 citations
  An unusual genomic variant of pancreatic ductal adenocarcinoma with an indolent clinical course.
  Zachary A. Kohutek, Lauren M. Rosati, Junguei Hong, Justin Poling, Marc A Attiyeh, Alvin Makohon-Moore, Joseph M. Herman, Christine A. Iacobuzio-Donahue> ;Cold Spring Harbor Molecular Case Studies. 2017 Jul 5
• 60 citations
  Transcriptional mechanisms of resistance to anti-PD-1 therapy
  Maria Libera Ascierto, Alvin Makohon-Moore, Evan J. Lipson, Janis M. Taube, Tracee L. McMiller, Alan E. Berger, Jinshui Fan, Genevieve J. Kaunitz, Tricia R. Cottrell, ...> ;Clinical Cancer Research. 2017 Jun 15
• 260 citations
  Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
  Alvin Makohon-Moore, Ming Zhang, Johannes G. Reiter, Ivana Bozic, Benjamin L. Allen, Deepanjan Kundu, Krishnendu Chatterjee, Fay Wong, Yuchen Jiao, Zachary A. Kohutek,...> ;Nature Genetics. 2017 Mar 1
• 25 citations
  Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer
  Yi Zhong, Anne Macgregor-Das, Tyler Saunders, Martin C. Whittle, Alvin Makohon-Moore, Zachary A. Kohutek, Justin Poling, Brian Herbst, Breanna Javier, Leslie Cope, Ste...> ;Clinical Cancer Research. 2017 Mar 15
• 17 citations
  Long-term Impact of Androgen-deprivation Therapy on Cardiovascular Morbidity After Radiotherapy for Clinically Localized Prostate Cancer
  Zachary A. Kohutek, Emily Weg, Xin Pei, Weiji Shi, Zhigang Zhang, Marisa A. Kollmeier, Michael J. Zelefsky> ;Urology. 2016 Jan 1
• 190 citations
  Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases.
  Zachary A. Kohutek, Yoshiya Yamada, Timothy A. Chan, Cameron Brennan, Viviane Tabar, Philip H. Gutin, T. Jonathan Yang, Marc K. Rosenblum, Åse Ballangrud, Robert J. Yo...> ;Journal of Neuro-Oncology. 2015 Aug 26
• 100 citations
  Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma
  Nemanja Rodić, Jared P. Steranka, Alvin Makohon-Moore, Allison Moyer, Peilin Shen, Reema Sharma, Zachary A. Kohutek, Cheng Ran Huang, Daniel Ahn, Paolo Mita, Martin S....> ;Nature Medicine. 2015 Sep 1
• 47 citations
  FDG-PET maximum standardized uptake value is prognostic for recurrence and survival after stereotactic body radiotherapy for non-small cell lung cancer
  Zachary A. Kohutek, Abraham J. Wu, Zhigang Zhang, A. Foster, S.U. Din, Ellen Yorke, Robert J. Downey, Kenneth E. Rosenzweig, Wolfgang A. Weber, Andreas Rimner> ;Lung Cancer. 2015 Aug 1
• 103 citations
  ADAM-10-Mediated N-Cadherin Cleavage Is Protein Kinase C-α Dependent and Promotes Glioblastoma Cell Migration
  Zachary A. Kohutek, Charles G. diPierro, Gerard T. Redpath, Isa M. Hussaini> ;The Journal of Neuroscience. 2009 Apr 8
• 34 citations
  Protein Kinase C-α–Mediated Regulation of Low-Density Lipoprotein Receptor–Related Protein and Urokinase Increases Astrocytoma Invasion
  Samson Amos, Melike Mut, Charles G. diPierro, Joan E. Carpenter, Aizhen Xiao, Zachary A. Kohutek, Gerard T. Redpath, Yunge Zhao, Jiahu Wang, Mark E. Shaffrey, Isa M. H...> ;Cancer Research. 2007 Nov 1
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Journal Articles

• Minimal Functional Driver Gene Heterogeneity Among Untreated Metastases  
  Marc A Attiyeh, Bert Vogelstein, Zachary A Kohutek, Science Magazine