ZeidKKayaliMD

Gastroenterology • Rialto, CA

Hepatology & Liver Transplantation

Associate Professor, Medicine, Loma Linda University School of Medicine

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Office
2006 N Riverside Ave Ste A
Rialto, CA 92377
Phone+1 909-883-2999

Fax+1 909-883-2997
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Summary

Dr. Zeid Kayali, MD is a gastroenterologist in Rialto, California. He is currently licensed to practice medicine in California, Nevada, and Iowa. He is affiliated with Arrowhead Regional Medical Center, Keck Hospital of USC, and St. Mary Medical Center Long Beach.

Education & Training

University of Southern California/LAC+USC Medical CenterFellowship, Gastroenterology, 2002 - 2004
University of Iowa Hospitals and ClinicsFellowship, Gastroenterology, 2001 - 2002
Catholic Health Partners ServicesResidency, Internal Medicine, 1997 - 2000
University of Aleppo Faculty of MedicineClass of 1995

Certifications & Licensure

CA State Medical License 2000 - 2026
NV State Medical License 2006 - 2025
IA State Medical License 2001 - 2003
IL State Medical License 1997 - 2002
American Board of Internal Medicine Gastroenterology

Clinical Trials

Treating Hispanic Patients Diagnosed With Hepatitis C Using Boceprevir Start of enrollment: 2011 Nov 01
Terminated
Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy Start of enrollment: 2013 Apr 03
Terminated
Phase 4
Collection of Plasma and Serum Samples From Individuals Initiating Sofosbuvir for Chronic Hepatitis C for Testing Start of enrollment: 2014 Feb 01
Completed
Short Duration Combination Therapy With Daclatasvir, Asunaprevir, BMS-791325 and Sofosbuvir in Subjects Infected With Chronic Hepatitis-C (FOURward Study) Start of enrollment: 2014 Jul 28
Completed
Phase 2
Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment Start of enrollment: 2015 Sep 22
Terminated
Phase 3
An Administration Method Study of Human Regular U-500 Insulin (LY041001) in Participants With Type 2 Diabetes Mellitus Start of enrollment: 2015 Oct 20
Completed
Phase 3
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis Start of enrollment: 2017 Dec 27
Completed
Phase 2
Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment Start of enrollment: 2018 Jun 22
Terminated
Phase 4
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Publications & Presentations

PubMed

Unravelling a Mysterious Skin Lesion in a Patient with Ulcerative Colitis.
Khaled Al-Smadi, Ammar Qureshi, Hasan Sqour, Ruijun Jeanna Su, Zeid Kayali> ;The American Journal of Medicine. 2024 Jan 1
1 citations
A randomised, double-blind, placebo-controlled study of the LAG-3-depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis.
Geert D'Haens, Laurent Peyrin-Biroulet, Daniel J B Marks, Edoardo Lisi, Lia Liefaard, Andrew Beaton, Naren Srinivasan, Gerben Bouma, Naveen Prasad, Raymond Cameron, Ze...> ;Alimentary Pharmacology & Therapeutics. 2023 Aug 1
66 citations
Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: A randomised, open-label phase I...
Naim Alkhouri, Robert Herring, Heidi Kabler, Zeid Kayali, Tarek Hassanein, Anita Kohli, Ryan S Huss, Yanni Zhu, Andrew N Billin, Lars Holm Damgaard, Kristine Buchholtz...> ;Journal of Hepatology. 2022 Sep 1
45 citations
EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study.
Vlad Ratziu, Mary E. Rinella, Brent A. Neuschwander-Tetri, Eric Lawitz, Douglas Denham, Zeid Kayali, Aasim Sheikh, Kris V. Kowdley, Taddese Desta, Magdy Elkhashab, Jef...> ;Journal of Hepatology. 2021 Nov 2
31 citations
Emricasan to prevent new decompensation in patients with NASH-related decompensated cirrhosis
Catherine Frenette, Zeid Kayali, Edward Mena, Parvez S. Mantry, Kathryn J. Lucas, Guy W. Neff, Miguel Á. Rodríguez, Paul J. Thuluvath, Ethan M. Weinberg, Bal R. Bhanda...> ;Journal of Hepatology. 2021 Feb 1
46 citations
Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study
Philip N. Newsome, Melissa Palmer, Bradley Freilich, Muhammad Y. Sheikh, Aasim Sheikh, Harry Sarles, Robert Herring, Parvez S. Mantry, Zeid Kayali, Tarek Hassanein, Ha...> ;Journal of Hepatology. 2020 Aug 1
190 citations
Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial
Keyur Patel, Stephen A. Harrison, Magdy Elkhashab, James F. Trotter, Robert Herring, Sergio Rojter, Zeid Kayali, Vincent Wai-Sun Wong, Susan Greenbloom, Saumya Jayakum...> ;Hepatology. 2020 Jul 1
24 citations
Variability and Lability of Ammonia Levels in Healthy Volunteers and Patients With Cirrhosis: Implications for Trial Design and Clinical Practice.
Jasmohan S. Bajaj, Patricia P. Bloom, Raymond T. Chung, Tarek Hassanein, Marielys Padilla-Martinez, Zeid Kayali, Don C. Rockey, Roula Sasso, Alagar Muthukumar, William...> ;The American Journal of Gastroenterology. 2020 May 1
139 citations
A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis.
Stephen A. Harrison, Zachary Goodman, Abdul Jabbar, Ravi Vemulapalli, Ziad Younes, Bradley Freilich, Muhammad Y. Sheikh, Jörn M. Schattenberg, Zeid Kayali, Adam Zivony...> ;Journal of Hepatology. 2020 May 1
92 citations
Lusutrombopag for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Invasive Procedures (L-PLUS 2)
Markus Peck-Radosavljevic, Krzysztof Simon, A. Iacobellis, Tarek Hassanein, Zeid Kayali, Albert Tran, Mihaly Makara, Ziv Ben Ari, Marius Braun, Paul Mitrut, Sheng-Shun...> ;Hepatology. 2019 Oct 1
208 citations
GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease
Rohit Loomba, Zeid Kayali, Mazen Noureddin, Peter Ruane, Eric Lawitz, Michael J. Bennett, L. Wang, Eliza Harting, Jacqueline M. Tarrant, B. Mccolgan, Chuhan Chung, Adr...> ;Gastroenterology. 2018 Nov 1
133 citations
Avatrombopag Before Procedures Reduces Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia.
Norah A. Terrault, Yi-Cheng Chen, Namiki Izumi, Zeid Kayali, Paul Mitrut, Won Young Tak, Lee F. Allen, Tarek Hassanein> ;Gastroenterology. 2018 Sep 1
Cumene hydroperoxide induced changes in oxidation-reduction potential in fresh and frozen seminal ejaculates.
Agarwal, A.,Sharma, R.,Henkel, R.,Roychoudhury, S.,Sikka, S. C.,du Plessis, S.,Sarda, Y. B.,Speyer, C.,Nouh, M.,Douglas, C.,Kayali, Z.,Elshaer, A.,Sabanegh, E.> ;Andrologia. 2017 Mar 16
27 citations
Short-duration treatment for chronic hepatitis C virus with daclatasvir, asunaprevir, beclabuvir and sofosbuvir (FOURward study)
Mark S. Sulkowski, Steve Flamm, Zeid Kayali, Eric Lawitz, Paul Y. Kwo, Fiona McPhee, Anne Torbeyns, Eric Hughes, Eugene S. Swenson, Philip D. Yin, Misti Linaberry> ;Liver International. 2017 Jun 1
176 citations
Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients With Cirrhosis and Hepatorenal Syndrome Type 1
Thomas D. Boyer, Arun J. Sanyal, Florence Wong, R. Todd Frederick, John R. Lake, Jacqueline G. O'Leary, Daniel Ganger, Khurram Jamil, Stephen Chris Pappas, Samuel H. S...> ;Gastroenterology. 2016 Jun 1
24 citations
Finally sofosbuvir: an oral anti-HCV drug with wide performance capability
Zeid Kayali, Warren N. Schmidt> ;Pharmacogenomics and Personalized Medicine. 2014 Dec 8
21 citations
Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation
Emilia Prakoso, Janina E.E. Tirnitz-Parker, Andrew D. Clouston, Z. Kayali, A. Lee, Eng K. Gan, Grant A. Ramm, James G. Kench, David G. Bowen, John K. Olynyk, Geoffrey ...> ;Liver Transplantation. 2014 Dec 1
707 citations
Sofosbuvir for previously untreated chronic hepatitis C infection.
Eric Lawitz, Alessandra Mangia, David Wyles, Maribel Rodriguez-Torres, Tarek Hassanein, Stuart C Gordon, Michael Schultz, Mitchell N Davis, Zeid Kayali, K Rajender Red...> ;The New England Journal of Medicine. 2013 May 16
133 citations
The safety and efficacy of high‐dose proton beam radiotherapy for hepatocellular carcinoma: a phase 2 prospective trial
David A. Bush, Zeid Kayali, Roger Grove, Jerry D. Slater> ;Cancer. 2011 Jul 1
17 citations
Increased plasma nitric oxide, L-arginine, and arginase-1 in cirrhotic patients with progressive renal dysfunction
Z. Kayali, Jason L. Herring, Pedro Baron, Edson Franco, Okechukwu Ojogho, Jason C. Smith, Gregory E. Watkins, Douglas C. Smith, Victor Lamin, Thanh Hoang, Rajiv Sharma...> ;Journal of Gastroenterology and Hepatology. 2009 Jun 1
17 citations
Risk factors for hepatitis C fibrosis: a prospective study of United States veterans compared with nonveterans.
Z. Kayali, S. Tan, Laura A. Shinkunas, M. Voigt, Douglas R. LaBrecque, Jack T. Stapleton, Kyle E. Brown, Warren N. Schmidt> ;Journal of Viral Hepatitis. 2007 Jan 1
7 citations
Treatment of hepatitis C cryoglobulinemia: mission and challenges.
Zeid Kayali, Douglas R. LaBrecque, Warren N. Schmidt> ;Current Treatment Options in Gastroenterology. 2006 Jan 1
20 citations
Hemosiderosis is associated with accelerated decompensation and decreased survival in patients with cirrhosis
Zeid Kayali, Rostislav Ranguelov, Frank A. Mitros, Chrisandra Shufelt, Farshad Elmi, Stephen C. Rayhill, Warren N. Schmidt, Kyle E. Brown> ;Liver International. 2005 Feb 1
118 citations
Hepatitis C, cryoglobulinemia, and cirrhosis: A meta‐analysis
Zeid Kayali, Victor E. Buckwold, Bridget Zimmerman, Warren N. Schmidt> ;Hepatology. 2002 Oct 1
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Press Mentions

Kintor Hits Back at Press Criticism of COVID Drug with US Trial UpdateMay 19th, 2021
NeuroBo Pharmaceuticals Receives First Site IRB Approval for Its Phase 2a Clinical Trial Evaluating DA-1241 for the Treatment of NASHAugust 4th, 2023

Hospital Affiliations

Keck Hospital of USCLos Angeles, California
St. Mary Medical Center Long BeachLong Beach, California
Arrowhead Regional Medical CenterColton, California