ZhiqiangBradWangMD

Pathology • Jacksonville, FL

Molecular Genetics, Anatomic Pathology, Clinical Pathology

Assistant Professor, Pathology, Immunology, & Laboratory Medicine, University of Florida College of Medicine

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Office
655 W 8th St
UF College of Medicine-Jacksonville Pathology
Jacksonville, FL 32209
Phone+1 904-244-4523
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Education & Training

UPMC Medical EducationFellowship, Molecular Genetic Pathology, 2009 - 2010
Methodist Hospital (Houston)Residency, Pathology-Anatomic and Clinical, 2005 - 2009
Shandong Medical UniversityClass of 1986

Certifications & Licensure

MI State Medical License 2017 - 2027
FL State Medical License 2010 - 2018
American Board of Pathology Pathology - Anatomic/Pathology - Clinical
American Board of Pathology Pathology - Molecular Genetic

Publications & Presentations

PubMed

2 citations
A center experience with lung transplantation for COVID-19 ARDS.
Domingo J Franco-Palacios, Lisa Allenspach, Lisa Stagner, Julio Pinto, Eve Sherbin, William Dillon, Daniel Sternberg, Kelly Bryce, Jane Simanovski, Dimitrios Apostolou...> ;Respiratory Medicine Case Reports. 2022 Jan 1
7 citations
The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling.
Annamil Alvarez-Trotta, Zhiqiang Wang, Elena Shersher, Bin Li, Jun Long, Ines Lohse, Claes Wahlestedt, Wael El-Rifai, David J. Robbins, Anthony J. Capobianco> ;Oncotarget. 2020 Aug 18
26 citations
Spatial distribution and sources of heavy metals in natural pasture soil around copper-molybdenum mine in Northeast China
Zhiqiang Wang, Chen Hong, Yi Xing, Kang Wang, Li Yifei, Feng Lihui, Silu Ma> ;Ecotoxicology and Environmental Safety. 2018 Jun 15
DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor.
Jing, Y.,Nguyen, M. M.,Wang, D.,Pascal, L. E.,Guo, W.,Xu, Y.,Ai, J.,Deng, F. M.,Masoodi, K. Z.,Yu, X.,Zhang, J.,Nelson, J. B.,Xia, S.,Wang, Z.> ;Oncogene. 2017 Oct 11
16 citations
Acetylation of Mastermind-like 1 by p300 Drives the Recruitment of NACK to Initiate Notch-Dependent Transcription
Ke Jin, Wen Zhou, Xiaoqing Han, Zhiqiang Wang, Bin Li, Shawn Jeffries, Wensi Tao, David J. Robbins, Anthony J. Capobianco> ;Cancer Research. 2017 Aug 15
4 citations
A Case Report of Mikulicz Syndrome.
Dinesh S. Rao, Patrick Natter, Rui Fernandes, Zhiqiang Brad Wang, Sukhwinder Johnny S Sandhu> ;Journal of Radiology Case Reports. 2017 Jul 26
30 citations
Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors
Bin Li, Darren Orton, Leif R. Neitzel, Luisana Astudillo, Chen Shen, Jun Long, Xi Chen, Kellye C. Kirkbride, Thomas Doundoulakis, Marcy L. Guerra, Julia Zaias, Dennis ...> ;Science Signaling. 2017 Jun 27
3 citations
DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications.
Shahla Masood, Ehab El-Gabry, Chuhua Zhang, Zhiqiang Wang> ;Laboratory Medicine. 2016 Nov 1
56 citations
The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.
Luisana Astudillo, Thiago G. da Silva, Zhiqiang Wang, Xiaoqing Han, Ke Jin, Jeffrey D. VanWye, Xiaoxia Zhu, Kelly L. Weaver, Taiji Oashi, Pedro E. M. Lopes, Darren Ort...> ;Cancer Research. 2016 Jun 15
8 citations
Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.
Bin Li, Camilla Giambelli, Bo Tang, Emily F. Winterbottom, Jun Long, Ke Jin, Zhiqiang Wang, Dennis Liang Fei, Dao M. Nguyen, Mohammad Athar, Baolin Wang, Pochi R. Subb...> ;Molecular Pharmacology. 2016 Feb 1
18 citations
The Notch signaling pathway in esophageal adenocarcinoma.
Zhiqiang Wang, J. Chen, Anthony J. Capobianco> ;Cellular and Molecular Biology. 2015 Oct 30
Hybrid molecule from Farnesylthiosalicylic acid-diamine and phenylpropenoic acid as Ras-related signaling inhibitor with potent antitumor activities
Yong Ling, Zhiqiang Wang, Xuemin Wang, Xianghua Li, Xinyang Wang, Wei Zhang, Hong Dai, Li Chen, Yihua Zhang> ;Chemical Biology & Drug Design. 2015 Feb 1
63 citations
Notch Signaling Drives Stemness and Tumorigenicity of Esophageal Adenocarcinoma
Zhiqiang Wang, Thiago G. da Silva, Ke Jin, Xiaoqin Han, Prathibha Ranganathan, Xiaoxia Zhu, Avencia Sanchez-Mejias, Feng Bai, Bin Li, Dennis Liang Fei, Kelly L. Weaver...> ;Cancer Research. 2014 Nov 1
59 citations
Pyrvinium attenuates Hedgehog signaling downstream of Smoothened
Bin Li, Dennis Liang Fei, Colin A. Flaveny, Nadia Dahmane, Valerie Baubet, Zhiqiang Wang, Feng Bai, Xin Hai Pei, Jezabel Rodriguez-Blanco, Brian I. Hang, Darren Orton,...> ;Cancer Research. 2014 Sep 1
NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis.
Weaver, K. L.,Alves-Guerra, M. C.,Jin, K.,Wang, Z.,Han, X.,Ranganathan, P.,Zhu, X.,DaSilva, T.,Liu, W.,Ratti, F.,Demarest, R. M.,Tzimas, C.,Rice, M.,Carpio, R. V.,Dahm...> ;Cancer Res.. 2014 Jul 20
Synthesis and biological evaluation of hybrids from farnesylthiosalicylic acid and hydroxylcinnamic acid with dual inhibitory activities of Ras-related signaling and p...
Yong Ling, Zhiqiang Wang, Xuemin Wang, Ying Zhao, Wei Zhang, Xinyang Wang, Li Chen, Zhangjian Huang, Yihua Zhang> ;Organic & Biomolecular Chemistry. 2014 Jul 7
7 citations
Synthesis and biological evaluation of farnesylthiosalicylamides as potential anti-tumor agents
Yong Ling, Zhiqiang Wang, Hongyan Zhu, Xuemin Wang, Wei Zhang, Xinyang Wang, Li Chen, Zhangjian Huang, Yihua Zhang> ;Bioorganic & Medicinal Chemistry. 2014 Jan 1
34 citations
The Hedgehog processing pathway is required for NSCLC growth and survival
Jezabel Rodriguez-Blanco, Neal S. Schilling, Robert Tokhunts, Camilla Giambelli, Jun Long, D. Liang Fei, Samer Singh, Kendall E. Black, Zhiqiang Wang, Fabrizio Galimbe...> ;Oncogene. 2013 May 2
38 citations
Hedgehog Signaling Regulates Bladder Cancer Growth And Tumorigenicity
Dennis Liang Fei, Avencia Sanchez-Mejias, Zhiqiang Wang, Colin A. Flaveny, Jun Long, Samer Singh, Jezabel Rodriguez-Blanco, Robert Tokhunts, Camilla Giambelli, Karolin...> ;Cancer Research. 2012 Sep 1
39 citations
Hedgehog-producing cancer cells respond to and require autocrine hedgehog activity
Samer Singh, Zhiqiang Wang, Dennis Liang Fei, Kendall E. Black, John A. Goetz, Robert Tokhunts, Camilla Giambelli, Jezabel Rodriguez-Blanco, Jun Long, Ethan Lee, Karol...> ;Cancer Research. 2011 Jul 1
42 citations
Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma
Zhiqiang Wang, Betsy Spaulding, Anna Sienko, Yiaoming Liang, Hongbao Li, Gitte Nielsen, Gyung Yub Gong, Jae Y. Ro, Qihui Jim Zhai> ;International Journal of Clinical and Experimental Pathology. 2009 Jun 19
11 citations
The laboratory opossum (Monodelphis domestica) as a natural mammalian model for human cancer research
Zhiqiang Wang, Gene B. Hubbard, Fred J. Clubb, John L. VandeBerg> ;International Journal of Clinical and Experimental Pathology. 2009 Jan 1
8 citations
[Gastrointestinal mesenchymal tumors: a clinical pathologic and immunohistochemical study of 210 cases].
Zhiqiang Wang, Shan Wang, Ying-Jiang Ye, Yi-Long Kang, Kun-Kun Sun, Hong-Fang Zheng> ;Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery. 2007 Jan 1
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Hospital Affiliations

Henry Ford HospitalDetroit, Michigan