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Ziyad Ayyoub, MD, Physical Medicine/Rehab, Paramount, CA, Kindred Hospital Paramount

ZiyadAyyoubMD

Physical Medicine/Rehab • Paramount, CA

Neurorehabilitation, Pain Medicine, Spinal Cord Injury Medicine

Clinical Professor of Medicine, David Geffen school of Medicine at UCLA, Clinical Professor, Physical Medicine & Rehabilitation, Western University of Health Sciences School of Medicine,

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Summary

  • Dr. Ziyad Ayyoub is a physiatrist in Paramount, CA and is affiliated with multiple hospitals in the area, including Lakewood Regional Medical Center, Promise Hospital of East Los Angeles, Suburban Medical Center Campus, and Kindred Hospital-La Mirada. He received his medical degree from Minsk Medical Institute and has been in practice 31 years. He also speaks multiple languages, including Arabic, Russian, and Spanish. He specializes in neurorehabilitation, pain medicine, and spinal cord injury medicine.

Education & Training

  • UCLA David Geffen School of Medicine/UCLA Medical Center/VA Greater Los Angeles Healthcare System
    UCLA David Geffen School of Medicine/UCLA Medical Center/VA Greater Los Angeles Healthcare SystemResidency, Physical Medicine and Rehabilitation, 1995 - 1998
  • Los Angeles County-Harbor-UCLA Medical Center
    Los Angeles County-Harbor-UCLA Medical CenterResidency, Surgery, 1993 - 1994
  • Minsk Medical Institute
    Minsk Medical InstituteClass of 1986
  • Belarus University
    Belarus UniversityDiploma, Russian Language and Sciences, 1979 - 1980

Certifications & Licensure

  • CA State Medical License
    CA State Medical License 1994 - 2025
  • American Board of Physical Medicine and Rehabilitation Physical Medicine & Rehabilitation
  • American Board of Physical Medicine and Rehabilitation Brain Injury Medicine

Awards, Honors, & Recognition

  • Ranked in the top 1% of physiatrists in USA by US News & world report newspaper multiple times
  • John E. Affeldt, MD Distinguished Physician Award 2011-2012 Rancho Los Amigos National Rehabilitation Center, 2011-2012
  • Top Doctors:LA Area Castle Connolly, 2013
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Dose-dependent effects of abobotulinumtoxinA (Dysport�) on MUSCLE TONE, spasticity and active movements in adults with upper limb spasticity: Secondary analysis of a P...  
    Michael W. O�Dell, Allison Brashear, Robert Jech, Thierry Lejeune, Philippe Marque, Djamel Bensmail, Ziyad Ayyoub, David Simpson, Anne Sophie Grandoulier, Claire Vilai..., Journal of PM&R, 1/1/2018
  • OnabotulinumtoxinA for Lower-Limb Spasticity: Guidance from a Delphi Panel Approach  
    Ayyoub Z, PM&R, 1/1/2017
  • OnabotulinumtoxinA injection for post-stroke upper-limb spasticity: Guidance for early injectors from a Delphi panel process  
    David M. Simpson, Atul T. Patel, Abraham Alfaro, Ziyad Ayyoub, David Charles, Khashayar Dashtipour, Alberto Esquenazi, IB Odderson, Journal of PM&R, 1/1/2017
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Books/Book Chapters

  • Spinal Cord Medicine Principles and Practice 
    Chapter: Dual Diagnosis: Spinal Cord Injury and Brain Injury 
    Ziyad Ayyoub, Fatima Badawi, Ann Vasile, Deborah Azaga, Amy Cassedy, and Vance ShawEditors: Vernon W. Lin.2005

Abstracts/Posters

  • Development of Heterotopic Ossification in the Setting of Burn Rehabilitation
    Punit Patel, Thomas Pham, Desi Barroga, Michael D. Scott, Ziyad Ayyoub, Association of Academic Physiatrists Annual Meeting, Las Vegas, NV, 1/7/2017
  • Right Lower Extremity weakness in a patient with iliopsoas Hematoma and Diabetic Amyotrophy Resulting in severe Lumbosacral Plexopathy: A Case Report
    David H. Nguyen, Ryan H Lee, Aliss Markosian, Michael Scott, Ziyad Ayyoub, CSPMR annual meeting, Long Beach, CA, 1/30/2016
  • Improvement of spasticity, active movements and active function after repeated injections of abobotulinumtoxinA (Dysport) in adults with spastic paresis in the upper l...
    Ayyoub Z, American Academy of Physical Medicine and Rehabilitation Annual Assembly and Technical Exhibition, New Orleans, LA, 1/20/2016
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Lectures

  • Brain Injury Epidemiology, Facts and Figures 
    Long Beach, CA - 1/27/2018
  • Gait Abnormalities in TBI 
    Long Beach, CA - 1/27/2018
  • Dosing of abobotulinumtoxinA (Dysport�) injections for adults with lower limb spasticity 
    Orlando, FL - 1/25/2018
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Research History

  • Prinicipla InvestigatorPrincipal Investigator on multiple grant-funded international research projects2000 - 2018
  • PI7/2007 Multicenter, Retrospective Chart Review of Adult patients Treated with Myobloc for Spasticity, protocol Number SN-SPAS-602
  • PIOctober, 2007 Multiple-Dose Efficacy and Safety Study of XP19986 in Subjects with Spasticity Due to Spinal Cord Injury, Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California A Multi-Center, Double-Blind, Placebo-Controlled Parallel, Rancho Los Amigo National Rehabilitation Cent
  • PIFeasibility Study of the Bioness Battery-Powered Microstimulator (BBPM) to Treat Chronic Shoulder Pain In Chronic Post-Stroke Subjects, 12/08, PI Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California
  • PIAugust 2010, Functional ambulation: Standard treatment vs. Electrical stimulation therapy(FASTEST) Trial in Chronic Post-Stroke Subjects with foot Drop, clinical protocol, CP-L300-0801,Rev. B , PI, Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California
  • PIA phase III, prospective, multicentre, open label, extension study, to assess the long term safety and efficacy of repeated treatment of disport intramuscular injection in the treatment of lower limb spasticity in adult subjects with spastic Hemiparesis due to stroke or traumatic brain injury STUDY
  • PIA phase III, multicentrre, double blind, prospective, randomized, placebo controlled study, assessing the efficacy and safety of dysport used for the treatment of lower limb spasticity in adult subjects with hemiparesis due to stroke or traumatic brain injury. STUDY PROTOCOL Study number Y-55-52120-
  • PIA PHASE III, MULTICENTRE, PROSPECTIVE, OPEN LABEL EXTENSION STUDY TO ASSESS THE LONG TERM SAFETY AND EFFICACY OF REPEATED TREATMENT OF DYSPORT INTRAMUSCULAR INJECTIONS USED FOR THE TREATMENT OF UPPER LIMB SPASTICITY IN ADULT SUBJECTS WITH SPASTIC HEMIPARESIS DUE TO STROKE OR TRAUMATIC BRAIN INJURY
  • PIProspective, double-blind, placebo-controlled, randomized, multi-center study with an open-label extension period to investigate the efficacy and safety of NT 201 in the treatment of post-stroke spasticity of the lower limb
  • PIProspective, double-blind, placebo-controlled, randomized, multi-center study with an open-label extension period to investigate the efficacy and safety of NT 201 in the treatment of post-stroke spasticity of the lower limb
  • PIProspective, double-blind, placebo-controlled, randomized, multi-centre study with an open-label extension period to investigate the efficacy and safety of NT 201 in the treatment of post-stroke spasticity of the upper limb”, Protocol No. “MRZ 60201/SP/300
  • PIOpen-label Study, Study Number: 191622-105 PI, Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California STUDY NUMBER: 191622-101 PI for these studies, Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California
  • PIAllergan 191622-116 BOTOX, Adult Post-Stroke Lower Limb Spasticity.
  • PI191622-127: BOTOX® Treatment in Adult Patients with Upper Limb Spasticity Multicenter, double-blind, randomized, placebo-controlled, parallel-group single treatment cycle, Principle Investigator, Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California
  • InvestigatorA Phase 2, Randomized, Double-Blind, 6-Sequence, Placebo-Controlled, 2-Period Multicenter Crossover Study to Evaluate the Safety and Efficacy of CTP-354 in Subjects with Spasticity due to Spinal Cord Injury co- Investigator, Rancho Los Amigo National Rehabilitation Center (RLANRC) Downey, California
  • PIA Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, Multi-Center Trial to Evaluate the Efficacy and Safety of DaxibotulinumtoxinA Injection for the Treatment of Upper Limb Spasticity (ULS) in Adults After Stroke or Traumatic Brain Injury
  • PIA Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Treatment Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity Followed by an Open-Label Extension, Multiple-Treatment Safety Study of MYOBLOC
  • PIINTERNATIONAL, MULTICENTRE, OBSERVATIONAL, PROSPECTIVE, LONGITUDINAL STUDY TO ASSESS THE EFFECTIVENESS OF ABOBONT-A INJECTIONS FOR ADULT LOWER LIMB SPASTICITY IN A REAL LIFE COHORT (ABOLISH)
  • PIA Multicentre, Interventional, Post-marketing, Randomised, Double-blind, Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA (Dysport®) in Comparison with OnabotulinumtoxinA (Botox®) when Treating Adults with Upper Limb Spasticity”
  • P!“A Multicentre, Interventional, Post-marketing, Randomised, Double-blind, Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA (Dysport®) in Comparison with OnabotulinumtoxinA (Botox®) when Treating Adults with Upper Limb Spasticity” in submission INTERNATIONAL, MULT
  • Priniciple InvestigatorINTERNATIONAL, MULTICENTRE, OBSERVATIONAL, PROSPECTIVE, LONGITUDINAL STUDY TO ASSESS THE EFFECTIVENESS OF ABOBONT-A INJECTIONS FOR ADULT LOWER LIMB SPASTICITY IN A REAL LIFE COHORT (ABOLISH) STUDY PROTOCOL, STUDY NUMBER: F-FR-52120-255, DYSPORT: 52120 in submission A Phase 2, Randomized, Double-Bli
  • Principle InvestigatorA Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, Multi-Center Trial to Evaluate the Efficacy and Safety of DaxibotulinumtoxinA Injection for the Treatment of Upper Limb Spasticity (ULS) in Adults after Stroke or Traumatic Brain Injury
  • Principle InvestigatorA Phase 2, Randomized, Double-Blind, 6-Sequence, Placebo-Controlled, 2-Period Multicenter Crossover Study to Evaluate the Safety and Efficacy of CTP-354 in Subjects with Spasticity due to Spinal Cord Injury

Professional Memberships

Other Languages

  • Arabic, Russian, Spanish

Hospital Affiliations

Dr. Ziyad Ayyoub, Dr. Ziyad Ayyoub, MD, Dr. Z Ayyoub