ZoharSachsMD

PubMed

• R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
  Liu, Z., Sinha, S., Bannister, M., Song, A., Arriaga-Gomez, E., McKeeken, A., Bonner, E., Hanson, B., Sarchi, M., Takashima, K., Zong, D., Corral, V., Nguyen, E., Yoo,...> ;Cancer Research. 2024 Feb 15
• Prospective evaluation of genome sequencing to compare conventional cytogenetics in acute myeloid leukemia.
  Beth A Pitel, Cinthya Zepeda-Mendoza, Zohar Sachs, Hongwei Tang, Suganti Shivaram, Neeraj Sharma, James B Smadbeck, Stephanie A Smoley, Kathryn E Pearce, Ivy M Luoma, ...> ;Blood Cancer Journal. 2023 Sep 6
• 1 citations
  Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma.
  Linda B Baughn, Erik Jessen, Neeraj Sharma, Hongwei Tang, James B Smadbeck, Mark D Long, Kathryn Pearce, Matthew Smith, Surendra Dasari, Zohar Sachs, Michael A Linden,...> ;Blood Cancer Journal. 2023 May 22
• 1 citations
  CD69 marks a subpopulation of acute myeloid leukemia with enhanced colony forming capacity and a unique signaling activation state.
  Marie Lue Antony, Daniel Chang, Klara E Noble-Orcutt, Anna Kay, Jeffrey L Jensen, Hesham Mohei, Chad L Myers, Karen Sachs, Zohar Sachs> ;Leukemia & Lymphoma. 2023 May 10
• Identification ofDownstream Genes with CRISPR Activation Screening.
  Akiya Tatsumi, Haruka Hirakochi, Satomi Inoue, Yosuke Tanaka, Hidehiro Furuno, Masumi Ikeda, Sachiko Ishibashi, Towako Taguchi, Kouhei Yamamoto, Iichiroh Onishi, Zohar...> ;Biology. 2022 Oct 23
• 3 citations
  Proliferation and Self-Renewal Are Differentially Sensitive to NRASG12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line.
  Morito Kurata, Marie Lue Antony, Klara E Noble-Orcutt, Susan K Rathe, Yoonkyu Lee, Hidehiro Furuno, Sachiko Ishibashi, Masumi Ikeda, Kouhei Yamamoto, Masanobu Kitagawa...> ;Molecular Cancer Research. 2022 Nov 3
• Lymphomatous infiltration of the kidney in a patient with Waldenstrom's macroglobulinemia.
  Prasanth Ravipati, Lihong Bu, Zohar Sachs, Patrick H Nachman> ;Clinical Nephrology. Case Studies. 2022 Jan 1
• 4 citations
  High risk of relapse with intermediate dose cytarabine for consolidation in young favourable-risk acute myeloid leukaemia patients following induction with 7+3: a retr...
  Bhaskar Kolla, Nurul Aidah Abdul Halim, Qing Cao, Zohar Sachs, Erica D. Warlick, Daniel J. Weisdorf, Aloysius Ho, Wong G. Chuan, Zhentang Lao, Fiona He> ;British Journal of Haematology. 2021 Apr 11
• 6 citations
  Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis
  Beth A. Pitel, Neeraj Sharma, Cinthya J. Zepeda-Mendoza, James B. Smadbeck, Kathryn E. Pearce, Joselle Cook, George Vasmatzis, Zohar Sachs, Rashmi Kanagal-Shamanna, Da...> ;Blood Cancer Journal. 2021 Feb 8
• 6 citations
  Primary Cardiac Lymphoma: Three Case Reports and a Review of the Literature
  Clifford M. Csizmar, Zohar Sachs, Zuzan Cayci, Lihong Bu, Michael A. Linden> ;Open Journal of Blood Diseases. 2021 Jan 1
• 2 citations
  Prognostic factors for clinical outcomes of patients with central nervous system leukemia
  Jinai Bharucha, Qing Cao, Zohar Sachs, Angela R. Smith, Sarah Williams, Khalid Amin, Veronika Bachanova, Erica D. Warlick, Claudio G. Brunstein, Daniel J. Weisdorf, Ne...> ;Hematology/oncology and Stem Cell Therapy. 2021 Sep 1
• 1 citations
  Evolution of clonal dynamics and differential response to targeted therapy in a case of systemic mastocytosis with associated myelodysplastic syndrome.
  Hyun Don Yun, Marie Lue Antony, Michael A. Linden, Klara E. Noble-Orcutt, Craig E. Eckfeldt, Celalettin Ustun, Andrew C. Nelson, Zohar Sachs> ;Leukemia Research. 2020 Jun 11
• 30 citations
  Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.
  Karen Sachs, Aaron L. Sarver, Klara E. Noble-Orcutt, Rebecca S. LaRue, Marie Lue Antony, Daniel Chang, Yoonkyu Lee, Connor Navis, Alexandria Hillesheim, Ian R. Nykaza,...> ;Cancer Research. 2020 Feb 1
• 3 citations
  Sarcoid-like Histiocytic Proliferations in Patients With Lymphoma Can Be FDG-avid Concerning for Refractory or Recurrent Disease
  Zuzan Cayci, Kerem Ozturk, Celalettin Ustun, Aazim K. Omer, Erhan H. Dincer, Zohar Sachs, Bruce A. Peterson, Michael A. Linden> ;Clinical Lymphoma, Myeloma & Leukemia. 2019 Aug 30
• 14 citations
  Multiomic Profiling of Tyrosine Kinase Inhibitor-Resistant K562 Cells Suggests Metabolic Reprogramming To Promote Cell Survival.
  Brett M Noel, Steven B. Ouellette, Laura J. Marholz, Deborah M. Dickey, Connor Navis, Tzu Yi Yang, Vinh Nguyen, Sarah J. Parker, David A. Bernlohr, Zohar Sachs, Laurie...> ;Journal of Proteome Research. 2019 Feb 7
• 2 citations
  Buccal epithelial cells display somatic, bone marrow-derived CALR mutation.
  Scott R Gilles, Linda B. Baughn, Matthew Schomaker, Elizabeth L. Courville, Andrew C. Nelson, Zohar Sachs> ;Blood Advances. 2017 Nov 28
• 6 citations
  Novel single-cell technologies in acute myeloid leukemia research
  Soumyasri Das Gupta, Zohar Sachs> ;Translational Research. 2017 Nov 1
• 13 citations
  Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry.
  Linda B. Baughn, Zohar Sachs, Klara E. Noble-Orcutt, Amit Kumar Mitra, Brian G Van Ness, Michael A. Linden> ;Leukemia & Lymphoma. 2017 Aug 3
• 45 citations
  Human Melanoma-Derived Extracellular Vesicles Regulate Dendritic Cell Maturation
  Rachel L. Maus, James W. Jakub, Wendy K. Nevala, Trace A. Christensen, Klara E. Noble-Orcutt, Zohar Sachs, Tina J. Hieken, Svetomir N. Markovic> ;Frontiers in Immunology. 2017 Mar 29
• 40 citations
  The role of the proteasome in AML
  Clifford M. Csizmar, Do Hyung Kim, Zohar Sachs> ;Blood Cancer Journal. 2016 Dec 2
• 14 citations
  Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency
  Zohar Sachs, Raha A. Been, Krista J. DeCoursin, Hanh Nguyen, Nurul Azyan Mohd Hassan, Klara E. Noble-Orcutt, Craig E. Eckfeldt, Emily J. Pomeroy, Ernesto Diaz-Flores, ...> ;Haematologica. 2016 Oct 1
• 30 citations
  Double- and triple-hit lymphomas can present with features suggestive of immaturity, including TdT expression, and create diagnostic challenges.
  Laura Moench, Zohar Sachs, Garth Aasen, Michelle M Dolan, Vanessa Dayton, Elizabeth L. Courville> ;Leukemia & Lymphoma. 2016 Feb 18
• 52 citations
  mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress.
  Young Sung Yun, Kwan Hyun Kim, Barbara R. Tschida, Zohar Sachs, Klara E. Noble-Orcutt, Branden S. Moriarity, Teng Ai, Rui Ding, Jessica Williams, Liqiang Chen, David A...> ;Molecular Cell. 2016 Feb 18
• 5 citations
  Novel disease burden assessment predicts allogeneic transplantation outcomes in myelodysplastic syndrome
  Bryan Trottier, Zohar Sachs, Todd E. DeFor, Leyla Shune, Michelle M Dolan, Daniel J. Weisdorf, Celalettin Ustun, Erica D. Warlick> ;Bone Marrow Transplantation. 2016 Feb 1
• 16 citations
  Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues.
  Aaron M. Kempema, John C. Widen, Joseph K. Hexum, Timothy E. Andrews, Dan Wang, Susan K. Rathe, Frederick Meece, Klara E. Noble, Zohar Sachs, David A. Largaespada, Dan...> ;Bioorganic & Medicinal Chemistry. 2015 Aug 1
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Abstracts/Posters

• High Risk of Relapse with Intermediate Dose Cytarabine for Consolidation in Young Favorable Risk AML Patients Following Induction with 7+3
  Zohar Sachs, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Cell Type-Specific Effects of Crizotinib in Human Acute Myeloid Leukemia with TP53 Alterations
  Zohar Sachs, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019