DavidSymmesWilliamsMD

PubMed

• 7 citations
  The ApoA-I mimetic peptide 4F attenuates in vitro replication of SARS-CoV-2, associated apoptosis, oxidative stress and inflammation in epithelial cells.
  Theodoros Kelesidis, Sharma Madhav, Anton Petcherski, Hugo Cristelle, Ellen I O’Connor, Nan W. Hultgren, Eleni Ritou, David S. Williams, Orian S. Shirihai, Srinivasa T...> ;Virulence. 2021 Dec 1
• 12 citations
  Cucurbit-Like Polymersomes with Aggregation-Induced Emission Properties Show Enzyme-Mediated Motility.
  Shoupeng Cao, Hanglong Wu, Imke A. B. Pijpers, Jingxin Shao, Loai K. E. A. Abdelmohsen, David S. Williams, Jan C. M. van Hest> ;ACS Nano. 2021 Oct 20
• 2 citations
  Non-toxic polymer nanovectors for improved delivery of dexamethasone.
  Benjamin C Ede, Paraskevi Diamanti, David S. Williams, Allison Blair> ;Scientific Reports. 2021 Aug 26
• 20 citations
  Biodegradable Polymersomes with Structure Inherent Fluorescence and Targeting Capacity for Enhanced Photo-Dynamic Therapy
  Shoupeng Cao, Yifeng Xia, Jingxin Shao, Beibei Guo, Yangyang Dong, Imke A. B. Pijpers, Zhiyuan Zhong, Fenghua Meng, Loai K. E. A. Abdelmohsen, David S. Williams, Jan C...> ;Angewandte Chemie. 2021 Aug 2
• 3 citations
  Comparison of Ciliary Targeting of Two Rhodopsin-Like GPCRs: Role of C-Terminal Localization Sequences in Relation to Cilium Type.
  Abhishek Chadha, Antonio E. Paniagua, David S. Williams> ;The Journal of Neuroscience. 2021 Jul 22
• 8 citations
  EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc-initiated colonic tumorigenesis.
  Camilla M. Reehorst, Rebecca Nightingale, Ian Y. Luk, Laura J. Jenkins, Frank Koentgen, David S. Williams, Charbel Darido, Fiona H Tan, Holly Anderton, Michael Chopin,...> ;Development. 2021 Jun 15
• Correction: BCL-XL is an actionable target for treatment of malignant pleural mesothelioma.
  Surein Arulananda, Megan O'Brien, Marco Evangelista, Tiffany J Harris, Nikita S. Steinohrt, Laura J. Jenkins, Marzena Walkiewicz, Robert J.J. O'Donoghue, Ashleigh R Po...> ;Cell Death Discovery. 2021 Jun 15
• 21 citations
  Host IL11 Signaling Suppresses CD4+ T cell–Mediated Antitumor Responses to Colon Cancer in Mice
  Jennifer Huynh, David Baloyan, David Chisanga, Wei Shi, Megan O'Brien, Shoukat Afshar-Sterle, Mariah G. Alorro, Lokman Pang, David S. Williams, Adam C. Parslow, Pathum...> ;Cancer Immunology Research. 2021 Apr 27
• 48 citations
  Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy
  Shoupeng Cao, Jingxin Shao, Hanglong Wu, Shidong Song, Maria Teresa De Martino, Imke A. B. Pijpers, Heiner Friedrich, Loai K. E. A. Abdelmohsen, David S. Williams, Jan...> ;Nature Communications. 2021 Apr 6
• 1 citations
  The IHC4+C score: an affordable and reproducible non-molecular decision-aid in hormone receptor-positive breast cancer. Does it still hold value for patients in 2020?
  Nadav Harel, Steven Cheema, David S. Williams, Kerryn Ireland-Jenkin, Tineke Fancourt, Andrew Dodson, Belinda Yeo> ;Asia-Pacific Journal of Clinical Oncology. 2021 Feb 10
• 10 citations
  Rapid resistance of FGFR-driven gastric cancers to regorafenib and targeted FGFR inhibitors can be overcome by parallel inhibition of MEK
  David K. Lau, Ian Y. Luk, Laura J. Jenkins, Andrew J. Martin, David S. Williams, Kael Schoffer, Fiona Chionh, Michael Buchert, Katrin Marie Sjoquist, Alex Boussioutas,...> ;Molecular Cancer Therapeutics. 2021 Apr 1
• 16 citations
  A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor-RPE interface.
  Cynthia Tang, Jimin Han, Sonal Dalvi, Kannan Vrindavan Manian, Lauren Winschel, Stefanie Volland, Celia Soto, Chad A. Galloway, Whitney Spencer, Michael Roll, Caroline...> ;Communications Biology. 2021 Feb 5
• 53 citations
  Exploring the Impact of Morphology on the Properties of Biodegradable Nanoparticles and Their Diffusion in Complex Biological Medium.
  Roxane Ridolfo, Shirin Tavakoli, Vijayabhaskarreddy Junnuthula, David S. Williams, Arto Urtti, Jan C. M. van Hest> ;Biomacromolecules. 2021 Jan 11
• 5 citations
  Key Role for CRB2 in the Maintenance of Apicobasal Polarity in Retinal Pigment Epithelial Cells.
  Antonio E. Paniagua, Alicia Segurado, Jorge F. Dolón, Julian Esteve-Rudd, Almudena Velasco, David S. Williams, Concepción Lillo> ;Frontiers in Cell and Developmental Biology. 2021 Jan 1
• PAS positive pseudofungi: a diagnostic pitfall.
  Stephanie Lau, David S. Williams> ;Pathology. 2021 Jun 1
• 7 citations
  Biopolymeric Coacervate Microvectors for the Delivery of Functional Proteins to Cells.
  Wenjin Xiao, Monika Jakimowicz, Ioannis Zampetakis, Sarah Neely, Fabrizio Scarpa, Sean A. Davis, David S. Williams, Adam W. Perriman> ;Advanced Biosystems. 2020 Nov 1
• 13 citations
  BCL-XL is an actionable target for treatment of malignant pleural mesothelioma.
  Surein Arulananda, Megan O'Brien, Marco Evangelista, Tiffany J Harris, Nikita S. Steinohrt, Laura J. Jenkins, Marzena Walkiewicz, Robert J.J. O'Donoghue, Ashleigh R Po...> ;Cell Death Discovery. 2020 Oct 31
• 47 citations
  Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis.
  Nan W. Hultgren, Jennifer S. Fang, Mary Ziegler, Ricardo Ramirez, Duc T. T. Phan, Michaela M.S. Hatch, Katrina M. Welch-Reardon, Antonio E. Paniagua, Lin S. Kim, Natha...> ;Nature Communications. 2020 Oct 26
• 38 citations
  Photoactivated Polymersome Nanomotors: Traversing Biological Barriers
  Jingxin Shao, Shoupeng Cao, David S. Williams, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest> ;Angewandte Chemie. 2020 Sep 21
• 24 citations
  Quantification of cristae architecture reveals time-dependent characteristics of individual mitochondria
  Mayuko Segawa, Dane M. Wolf, Nan W. Hultgren, David S. Williams, Alexander M. van der Bliek, David B. Shackelford, Marc Liesa, Orian S. Shirihai> ;Life Science Alliance. 2020 Jul 1
• 37 citations
  Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis
  Imke A. B. Pijpers, Shoupeng Cao, Antoni Llopis-Lorente, Jianzhi Zhu, Shidong Song, Rick R. M. Joosten, Fenghua Meng, Heiner Friedrich, David S. Williams, Samuel Sanch...> ;Nano Letters. 2020 May 22
• 7 citations
  Wormlike Nanovector with Enhanced Drug Loading Using Blends of Biodegradable Block Copolymers.
  Roxane Ridolfo, Jeanrick J Arends, Jan C. M. van Hest, David S. Williams> ;Biomacromolecules. 2020 Jun 8
• 9 citations
  Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer.
  David S. Williams, Dmitri Mouradov, Clare Browne, Michelle Palmieri, Meg J. Elliott, Rebecca Nightingale, Catherine G Fang, Rita Li, John M. Mariadason, Ian Faragher, ...> ;Modern Pathology. 2020 Mar 1
• 5 citations
  A case of ANCA-associated vasculitis presenting de novo in pregnancy, successfully treated with rituximab
  A Pefanis, David S. Williams, H Skrzypek, A Fung, Kathy Paizis> ;Obstetric Medicine. 2020 Mar 1
• 15 citations
  Multistep peripherin-2/rds self-assembly drives membrane curvature for outer segment disk architecture and photoreceptor viability.
  Michelle Lynn Milstein, Breyanna Lynn Cavanaugh, Nicole M Roussey, Stefanie Volland, David S. Williams, Andrew F.X. Goldberg> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Feb 25
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Lectures

• Deletion of Murine Rhoh induces More Aggressive Diffuse Large B Cell Lymphoma (DLBCL) Via Interaction with Kaiso and Regulation of BCL-6 Expression 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018