ElliotStieglitzMD

PubMed

• Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
  Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik Kang, Nikhil Chilakapati, Naomi Akagi, Haley Johnson, Tasfia Rashid, Juwita Werner, Abhilash Barpanda, Huim...> ;Biorxiv. 2024 Feb 28
• 1 citations
  Desensitization using pegaspargase in the era of commercially available Erwinia: A single-institution report on efficacy, cost, and resource utilization.
  Feldman, K., Aaronson, K., Gu, T., Ige, K., Southworth, E., Sanchez, L., Stieglitz, E.> ;Pediatric Blood & Cancer. 2024 Apr 1
• Nivolumab Plus 5-Azacitidine in Pediatric Relapsed/Refractory Acute Myeloid Leukemia (AML): Phase I/II Trial Results from the Therapeutic Advances in Childhood Leukemi...
  Verma, A., Chi, Y., Malvar, J., Lamble, A., Chaudhury, S., Agarwal, A., Li, H., Liang, G., Leong, R., Brown, P., Kaplan, J., Schafer, E., Slone, T., Pauly, M., Chang, ...> ;Cancers. 2024 Jan 24
• LNK/as a novel driver in juvenile myelomonocytic leukemia.
  Astrid Wintering, Anna Hecht, Julia Meyer, Eric B Wong, Juwita Hübner, Sydney Abelson, Kira Feldman, Vanessa E Kennedy, Cheryl A C Peretz, Deborah L French, Jean Ann M...> ;Haematologica. 2023 Dec 28
• Too many white cells-TAM, JMML, or something else?
  Satty, A., Stieglitz, E., Kucine, N.> ;Hematology. American Society of Hematology. Education Program. 2023 Dec 8
• 1 citations
  Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies.
  William C Temple, Matthew A Nix, Akul Naik, Adila Izgutdina, Benjamin J Huang, Gianina Wicaksono, Paul Phojanakong, Juan Antonio Camara Serrano, Elizabeth P Young, Emi...> ;Journal for Immunotherapy of Cancer. 2023 Nov 24
• 1 citations
  Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.
  Bogdan Popescu, Carlos Stahlhut, Theodore C Tarver, Sydney Wishner, Bianca J Lee, Cheryl A C Peretz, Cuyler Luck, Paul Phojanakong, Juan Antonio Camara Serrano, Henry ...> ;Cell Reports. Medicine. 2023 Nov 21
• The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy.
  Elizabeth I Pierpont, Anton M Bennett, Lisa Schoyer, Beth Stronach, April Anschutz, Sarah C Borrie, Benjamin Briggs, Emma Burkitt-Wright, Pau Castel, Ion C Cirstea, Fi...> ;American Journal of Medical Genetics. Part A. 2024 Apr 1
• Pre-and post-HSCT use of TKI therapy for fusion-driven B-ALL: A case series of five pediatric, adolescent and young adult patients.
  Savannah S Shumock, William C Temple, Amanda Marinoff, Kathryn Aaronson, Erica Southworth, Simayijiang Xirenayi, Alex G Lee, Stanley G Leung, E Alejandro Sweet-Cordero...> ;Cancer Reports. 2023 Dec 1
• 1 citations
  Structural surfaceomics reveals an AML-specific conformation of integrin βas a CAR T cellular therapy target.
  Kamal Mandal, Gianina Wicaksono, Clinton Yu, Jarrett J Adams, Michael R Hoopmann, William C Temple, Adila Izgutdina, Bonell Patiño Escobar, Maryna Gorelik, Christian H...> ;Nature Cancer. 2023 Nov 1
• Tretinoin Enhances the Effects of Chemotherapy in Juvenile Myelomonocytic Leukemia Using an Ex Vivo Drug Sensitivity Assay.
  Elliot Stieglitz, Christine J Gu, Michelle Richardson, Ryosuke Kita, Marianne T Santaguida, Kamran A Ali, Debbie C Strachan, Anukriti Dhar, George Yam, Wade Anderson, ...> ;JCO Precision Oncology. 2023 Sep 1
• 4 citations
  Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies.
  Amanda E Marinoff, Kathryn Aaronson, Anurag K Agrawal, Benjamin S Braun, Carla Golden, Benjamin J Huang, Jennifer Michlitsch, Erica Southworth, Allyson Thrall, Kieuhoa...> ;Pediatric Blood & Cancer. 2023 Jun 1
• 2 citations
  Potential clinical use of azacitidine and MEK inhibitor combination therapy in PTPN11-mutated juvenile myelomonocytic leukemia.
  Santhosh Kumar Pasupuleti, Karen Chao, Baskar Ramdas, Rahul Kanumuri, Lakshmi Reddy Palam, Sheng Liu, Jun Wan, Colleen Annesley, Mignon L Loh, Elliot Stieglitz, Michae...> ;Molecular Therapy. 2023 Apr 5
• 4 citations
  Classification of rare pediatric myeloid neoplasia-Quo vadis?
  Charlotte M Niemeyer, Martina Rudelius, Akiko Shimamura, Christian Flotho, Henrik Hasle, Elliot Stieglitz, Brigitte Strahm, Lucy A Godley, Olga K Weinberg, Attilio Ora...> ;Leukemia. 2022 Dec 1
• 4 citations
  Paediatric Strategy Forum for medicinal product development in mitogen-activated protein kinase pathway inhibitors: ACCELERATE in collaboration with the European Medic...
  Andrew Dj Pearson, Carl Allen, Jason Fangusaro, Caroline Hutter, Olaf Witt, Susan Weiner, Gregory Reaman, Mark Russo, Pratiti Bandopadhayay, Sama Ahsan, Amy Barone, El...> ;European Journal of Cancer. 2022 Dec 1
• 24 citations
  MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus.
  Peter M K de Blank, Andrea M Gross, Srivandana Akshintala, Jaishri O Blakeley, Gideon Bollag, Ashley Cannon, Eva Dombi, Jason Fangusaro, Bruce D Gelb, Darren Hargrave,...> ;Neuro-Oncology. 2022 Nov 2
• Clinical parameter-based prediction of DNA methylation classification generates a prediction model of prognosis in patients with juvenile myelomonocytic leukemia.
  Takahiro Imaizumi, Julia Meyer, Manabu Wakamatsu, Hironobu Kitazawa, Norihiro Murakami, Yusuke Okuno, Taro Yoshida, Daichi Sajiki, Asahito Hama, Seiji Kojima, Yoshiyuk...> ;Scientific Reports. 2022 Aug 30
• 2 citations
  Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy.
  Stephen M Smith, Alex Lee, Schuyler Tong, Stanley Leung, Henry Hongo, Jose Rivera, Alejandro Sweet-Cordero, Jennifer Michlitsch, Elliot Stieglitz> ;Cold Spring Harbor Molecular Case Studies. 2022 Aug 4
• 1 citations
  Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
  Baskar Ramdas, Lisa Deng Yuen, Lakshmi Reddy Palam, Roshini Patel, Santhosh Kumar Pasupuleti, Victoria Jideonwo, Ji Zhang, Callista Maguire, Eric Wong, Rahul Kanumuri,...> ;Molecular Therapy. 2022 Jul 6
• 1 citations
  Cytomorphologic features of pediatric-type follicular lymphoma on fine needle aspiration biopsy: case series and a review of the literature.
  Kevin L Lu, Joshua R Menke, David Ng, Roberto Ruiz-Cordero, Amanda Marinoff, Elliot Stieglitz, Sumanth Gollapudi, Kunwar Singh, Robert S Ohgami, Poonam Vohra> ;Journal of the American Society of Cytopathology. 2022 Jun 22
• Therapy-related myeloid neoplasms resembling juvenile myelomonocytic leukemia: a case series and review of the literature.
  Astrid Wintering, Beng Fuh, Arun Rangaswami, Gary Dahl, May Chien, Tanja A Gruber, Jinjun Dang, Loretta S Li, Alicia Lenzen, Stephanie Savelli, Christopher C Dvorak, A...> ;Pediatric Blood & Cancer. 2022 May 1
• 2 citations
  A simple and robust methylation test for risk stratification of patients with juvenile myelomonocytic leukemia.
  Hironobu Kitazawa, Yusuke Okuno, Hideki Muramatsu, Kosuke Aoki, Norihiro Murakami, Manabu Wakamatsu, Kyogo Suzuki, Kotaro Narita, Shinsuke Kataoka, Daisuke Ichikawa, M...> ;Blood Advances. 2021 Sep 27
• 3 citations
  JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β.
  Yuhan Yan, Lei Dong, Chao Chen, Kevin D. Bunting, Qianjin Li, Elliot Stieglitz, Mignon L. Loh, Cheng-Kui Qu> ;Blood Advances. 2021 Sep 23
• 10 citations
  Juvenile myelomonocytic leukemia in the molecular era: a clinician's guide to diagnosis, risk stratification, and treatment.
  Astrid Wintering, Christopher C. Dvorak, Elliot Stieglitz, Mignon L. Loh> ;Blood Advances. 2021 Nov 23
• 2 citations
  Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia
  Carolina E. Morales, Elliot Stieglitz, Scott C. Kogan, Mignon L. Loh, Benjamin S. Braun> ;Blood Advances. 2021 Sep 28
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Journal Articles

• Downregulating Notch Counteracts KrasG12D-Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm  
  Erik A Ranheim, David Yang, Warren S Pear, Lan Zhou, Mignon Loh, Eric Padron, Elliot Stieglitz, Nature

Abstracts/Posters

• In Vitro-Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies
  Elliot Stieglitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation
  Elliot Stieglitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

• Phase I Study of the Selinexor in Relapsed/Refractory Childhood Acute Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018