Francis Xavier Mccormack MD

Interstitial Lung Diseases, Restrictive Lung Disease

Taylor Professor and Director, Division of Pulmonary, Critical Care and Sleep Medicine

200 Eden AveCincinnati, OH 45220
Phone+1 513-475-8523
Fax+1 513-475-1327

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Summary

Dr. Francis Mccormack is a pulmonologist in Cincinnati, OH and is affiliated with multiple hospitals in the area, including University of Cincinnati Medical Center, Cincinnati Veterans Affairs Medical Center, Daniel Drake Center for Post Acute Care, and Cincinnati Children's Hospital Medical Center. He received his medical degree from University of Texas Medical Branch and has been in practice 35 years. He specializes in interstitial lung diseases and pleural disease and is experienced in interstitial lung disease, lymphangioleiomyomatosis, critical care medicine, and rare lung diseases.

Education & Training

University of ColoradoFellowship, Pulmonary Disease and Critical Care Medicine, 1986 - 1989
University of MichiganChief Residency, Internal Medicine, 1985 - 1986
University of MichiganResidency, Internal Medicine, 1982 - 1985
University of Texas Medical Branch School of MedicineClass of 1982

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Certifications & Licensure

OH State Medical License 1994 - 2028
CO State Medical License 1986 - 1995
MI State Medical License 1985 - 1992
TX State Medical License 1983 - 1987
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Elected Member Association of American Physicians, 2016
Elected Member Alpha Omega Alpha, 2012
Top 10 US Clinicial Research Achievements of 2011 Clinical Research Forum, 2011

Clinical Trials

Efficacy and Safety of Sirolimus in LAM Start of enrollment: 2006 Dec 01
Completed
Phase 3
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) Start of enrollment: 2009 Apr 01
Completed
Phase 3
Letrozole for Lymphangioleiomyomatosis Start of enrollment: 2011 May 01
Completed
Phase 2

Publications & Presentations

PubMed

High-Throughput Proteomics in Lymphangioleiomyomatosis: Premelanosome Protein as a Diagnostic Biomarker, Construction of a Diagnosis Score, and Evidence of Neutrophil ...
Rémi Diesler, Tiegang Han, Wendy K Steagall, Samer Salem, Damir Khabibullin
Chest. 2026-06-01
Alveolar-Basal Intermediates Drive Pulmonary Fibrosis via Coordination of a Pro-Fibrotic Signaling Niche in Silicosis.
Barbara Zhao, Helen I Warheit-Niemi, Kathleen C S Cook, Lori Pitstick, Andrea Toth
Biorxiv. 2026-03-14
3 citations
Hyperactivation of mTORC1 signaling mediates folliculin deficiency-induced pulmonary cyst formation in Birt-Hogg-Dubé syndrome.
Ke Cao, Hui Chen, Ling Chu, Hong-Jun Wang, Jianhua Zhang
The Journal of Clinical Investigation. 2026-02-16

Journal Articles

The Vitamin D Binding Protein Axis Modifies Disease Severity in Lymphangioleiomyomatosis
Francis Mccormack, MD, The European Respiratory Journal
efficacy and safety of sirolimus

Press Mentions

Innovative Imaging, Surgery Treats Lymph Condition in AdultsJanuary 10th, 2017

Grant Support

Pulmonary Development and Disease Pathogenesis Training ProgramCINCINNATI CHILDRENS HOSP MED CTR1994–2030
Novel Mechanisms of Pulmonary FibrosisUNIVERSITY OF CINCINNATI2023–2027
Role of Pulmonary Osteoclast-Like Cells in Lung InjuryCINCINNATI VA MEDICAL CENTER RESEARCH2021–2025
Multicenter Interventional Lymphangioleiomyomatosis Early Disease Trial (MILED)-CCCUNIVERSITY OF CINCINNATI2016–2025
Pathogenesis-Driven Therapeutic Development for Pulmonary Alveolar MicrolithiasisNational Heart, Lung and Blood Institute2015–2019

Committees

Member, FDA Pulmonary and Allergy Drug Advisory Committee 2013 - 2015
Member, American Board of Internal Medicine Pulmonary Board 2013 - 2015
Member, Department of Defense Tuberous Sclerosis Program Vision Setting Committee 2012 - 2015