JamesEdwardMoonMDFACP, FIDSA

Infectious Disease • Silver Spring, MD

Associate Director, Center for Enabling Capabilities, Walter Reed Army Institute of Research

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Office
503 Robert Grant Avenue
Silver Spring, MD 20910
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Education & Training

San Antonio Uniformed Services Health Education ConsortiumFellowship, Infectious Disease, 2003 - 2006
Tripler Army Medical CenterResidency, Internal Medicine, 2000 - 2003
Pennsylvania State University College of MedicineClass of 2000

Certifications & Licensure

HI State Medical License 2002 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Clinical Trials

Merozoite Surface Protein 1 Antibody Response in Asymptomatic Human Malaria Infection Start of enrollment: 2008 Sep 01
Completed
Not Applicable
Evaluation of Three Potential Central Nervous System (CNS) Pretreatments for Soman Exposure on Human Performance Start of enrollment: 2012 Feb 01
Completed
Study to Evaluate the Safety, Tolerability, and Immunogenicity of Hantaan and Puumala Virus DNA Vaccines Start of enrollment: 2012 Jan 01
Completed
Phase 1
Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic Fever Start of enrollment: 2014 Jul 09
Completed
Phase 2
Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults Start of enrollment: 2014 Aug 01
Completed
Phase 1
A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses Start of enrollment: 2014 Jun 01
Completed
Phase 1
TDENV PIV and LAV Dengue Prime-boost Strategy Start of enrollment: 2014 Dec 01
Completed
Phase 1
Vaccine Treatment for Ebola Virus in Healthy Adults (V920-001) Start of enrollment: 2014 Oct 13
Completed
Phase 1
Genetic Variability in CYP2D6 in U.S Active Duty Population Start of enrollment: 2016 Jan 08
Completed
Phase 1
Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54 Start of enrollment: 2019 Mar 04
Completed
Phase 1
A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults Start of enrollment: 2020 Mar 20
Recruiting
Phase 1
A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults Start of enrollment: 2020 Mar 20
Recruiting
Phase 1
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Publications & Presentations

PubMed

13 citations
Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Michele D Spring, Jason C Sousa, Qigui Li, Christian A Darko, Meshell N Morrison, Sean R Marcsisin, Kristin T Mills, Brittney M Potter, Kristopher M Paolino, Patrick S...> ;The Journal of Infectious Diseases. 2019 Oct 22
Oa Safety and Immunogenicity of a Tetravalent Dengue DNA Vaccine Administered with a Cationic Lipid-Based Adjuvant in a Phase 1 Clinical Trial
Thomas Luke, James Moon, Janine R Danko> ;The American Journal of Tropical Medicine and Hygiene.
17 citations
Limited Efficacy of Caffeine and Recovery Costs During and Following 5 Days of Chronic Sleep Restriction
T J Doty, Christine J So, Elizabeth M Bergman, Sara K Trach, Ruthie H Ratcliffe, Angela M. Yarnell, Vincent F. Capaldi, James E. Moon, Thomas J. Balkin, Phillip J. Qua...> ;Sleep. 2017 Dec 1
268 citations
A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report
Jason A. Regules, John H. Beigel, Kristopher M. Paolino, Jocelyn Voell, Amy R. Castellano, Zonghui Hu, Paula Muñoz, James E. Moon, Richard C. Ruck, Jason W. Bennett, P...> ;The New England Journal of Medicine. 2017 Jan 26
165 citations
Protection against Plasmodium falciparum malaria by PfSPZ Vaccine
Judith E. Epstein, Kristopher M. Paolino, Thomas L. Richie, Martha Sedegah, Alexandra Singer, Adam Ruben, Sumana Chakravarty, April Stafford, Richard C. Ruck, Abraham ...> ;JCI Insight. 2017 Jan 12
23 citations
A Unified Model of Performance for Predicting the Effects of Sleep and Caffeine.
Sridhar Ramakrishnan, Nancy J. Wesensten, Gary H. Kamimori, James E. Moon, Thomas J. Balkin, Jaques Reifman> ;Sleep. 2016 Oct 1
149 citations
Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study
Jason A. Regules, Susan Cicatelli, Jason W. Bennett, Kristopher M. Paolino, Patrick S. Twomey, James E. Moon, April K. Kathcart, Kevin Hauns, Jack Komisar, Aziz N. Qab...> ;The Journal of Infectious Diseases. 2016 Sep 1
66 citations
Ad35.CS.01 - RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults
Christian F. Ockenhouse, Jason A. Regules, Donna Tosh, Jessica Cowden, April K. Kathcart, James F. Cummings, Kristopher M. Paolino, James E. Moon, Jack Komisar, Edwin ...> ;Plos One. 2015 Jul 6
11 citations
Physiological and neurobehavioral effects of cholinesterase inhibition in healthy adults.
Katherine C. Morasch, Christopher L. Aaron, James E. Moon, Richard K. Gordon> ;Physiology & Behavior. 2015 Jan 1
41 citations
A Phase 1 clinical trial of Hantaan virus and Puumala virus M-segment DNA vaccines for haemorrhagic fever with renal syndrome delivered by intramuscular electroporation
Jay W. Hooper, James E. Moon, Kristopher M. Paolino, R. Newcomer, D.E. McLain, Matthew D. Josleyn, Drew Hannaman, Connie S. Schmaljohn> ;Clinical Microbiology and Infection. 2014 May 1
53 citations
Safety and immunogenicity of a plant-produced recombinant monomer hemagglutinin-based influenza vaccine derived from influenza A (H1N1)pdm09 virus: A Phase 1 dose-esca...
James F. Cummings, Melanie L. Guerrero, James E. Moon, Paige E. Waterman, Robin K. Nielsen, Stacie Jefferson, F. Liaini Gross, Kathy Hancock, Jacqueline M. Katz, Vidad...> ;Vaccine. 2014 Apr 17
49 citations
A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recru...
Robert A. Kuschner, Kevin L. Russell, Mary Abuja, Kristen M Bauer, Dennis J. Faix, Howard Hait, Jennifer Henrick, Michael Jacobs, Alan Liss, Julia Lynch, Qi Liu, Arthu...> ;Vaccine. 2013 Jun 19
3 citations
Plasmodium falciparum Infection during Suppressive Prophylaxis with Mefloquine Does Not Induce an Antibody Response to Merozoite Surface Protein-1(42)
James E. Moon, Gregory Deye, Lori Miller, Susan Fracisco, R. Scott Miller, Donna Tosh, James F. Cummings, Colin Ohrt, Alan J. Magill> ;The American Journal of Tropical Medicine and Hygiene. 2011 May 5
116 citations
A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protei...
Paul B. Keiser, S. Biggs-Cicatelli, E. E. Moran, Deborah H. Schmiel, Valerian B. Pinto, Robert Burden, Lori Miller, James E. Moon, Robert A. Bowden, James F. Cummings,...> ;Vaccine. 2011 Feb 4
Effects of a reduced dose schedule and intramuscular administration of anthrax vaccine adsorbed on immunogenicity and safety at 7 months: a randomized trial.
Marano N Plikaytis BD Martin SW Rose C Semenova VA Martin SK Freeman AE Li H Mulligan MJ Parker SD Babcock J Keitel W El Sahly H Poland GA Jacobson RM K...> ;JAMA. 2008 Oct 1
13 citations
Efficacy of caspofungin and posaconazole in a murine model of disseminated Exophiala infection
Robert G. Rivard, Suzanne McCall, Matthew E. Griffith, Joshua S. Hawley, Roseanne A. Ressner, Himabindu Borra, James E. Moon, Miriam L. Beckius, Clinton K. Murray, Dua...> ;Medical Mycology. 2007 Dec 1
20 citations
Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.
Matthew E. Griffith, James E. Moon, Erica N. Johnson, Kyra P. Clark, Joshua S. Hawley, Duane R. Hospenthal, Clinton K. Murray> ;Antimicrobial Agents and Chemotherapy. 2007 Jul 1
6 citations
Effect of timing and duration of azithromycin therapy of leptospirosis in a hamster model
James E. Moon, Robert G. Rivard, Matthew E. Griffith, Roseanne A. Ressner, Suzanne McCall, Raven E Reitstetter, Duane R. Hospenthal, Clinton K. Murray> ;The Journal of Antimicrobial Chemotherapy. 2006 Oct 28
20 citations
Efficacy of Macrolides and Telithromycin against Leptospirosis in a Hamster Model
James E. Moon, Michael C. Ellis, Matthew E. Griffith, Joshua S. Hawley, Robert G. Rivard, Suzanne McCall, Duane R. Hospenthal, Clinton K. Murray> ;Antimicrobial Agents and Chemotherapy. 2006 Jun 1
12 citations
Viability of Leptospira in BacT/ALERT MB media.
Matthew E. Griffith, Lynn L. Horvath, Walter V. Mika, Joshua S. Hawley, James E. Moon, Duane R. Hospenthal, Clinton K. Murray> ;Diagnostic Microbiology and Infectious Disease. 2006 Apr 1
10 citations
Prevalence of leptospira antibodies in U.S. Army blood bank donors in Hawaii.
Christopher Lettieri, James Moon, Patrick Hickey, Michael R. Gray, Benjamin W Berg, Duane R. Hospenthal> ;Military Medicine. 2004 Sep 1
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