JenniferSGuimbellotMD

PubMed

• 2 citations
  Mobile health platform for self-management of pediatric cystic fibrosis: Impact on patient-centered care outcomes.
  Gabriela R Oates, Cathy Mims, Robin Geurs, Rikard Bergquist, Andreas Hager, Jennifer S Guimbellot, Anastasia M Hartzes, Hector H Gutierrez> ;Journal of Cystic Fibrosis. 2023 Sep 1
• Pharmacogenetic actionability and medication prescribing in people with cystic fibrosis.
  Justin D Anderson, Brittney H Davis, Gracie Giang, April Jones, Cameron R Lee, Kennedy Parker, Heather Searcy, Kim Benner, Nita A Limdi, Jennifer S Guimbellot> ;Clinical and Translational Science. 2023 Apr 1
• 1 citations
  Electronic screening for unmet social needs in a pediatric pulmonary clinic: Acceptability and associations with health outcomes.
  Gabriela R Oates, Lindsay Lock, Valerie Tarn, Robin Geurs, Jennifer S Guimbellot, Elizabeth Baker, Teresa Magruder> ;Pediatric Pulmonology. 2023 May 1
• 5 citations
  Outcomes of children with cystic fibrosis screen positive, inconclusive diagnosis/CFTR related metabolic syndrome.
  Mohini A Gunnett, Elizabeth Baker, Cathy Mims, Staci T Self, Hector H Gutierrez, Jennifer S Guimbellot> ;Frontiers in Pediatrics. 2023 Jan 1
• 2 citations
  Novel Applications of Biomarkers and Personalized Medicine in Cystic Fibrosis.
  Jennifer S Guimbellot, David P Nichols, John J Brewington> ;Clinics in Chest Medicine. 2022 Dec 1
• 3 citations
  Quantitation of cystic fibrosis triple combination therapy, elexacaftor/tezacaftor/ivacaftor, in human plasma and cellular lysate.
  Kevin J Ryan, Jennifer S Guimbellot, Alexander E Dowell, Kedria D Reed-Walker, Corenna D Kerstner-Wood, Justin D Anderson, Zhongyu Liu, Edward P Acosta> ;Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 2022 Dec 15
• 2 citations
  Plasma and cellular ivacaftor concentrations in patients with cystic fibrosis.
  Jennifer S Guimbellot, Kevin J Ryan, Justin D Anderson, Kennedy L Parker, Lauren Victoria Odom, Steven M Rowe, Edward P Acosta> ;Pediatric Pulmonology. 2022 Nov 1
• 23 citations
  Use of elexacaftor/tezacaftor/ivacaftor among cystic fibrosis lung transplant recipients.
  Kathleen J Ramos, Jennifer S Guimbellot, Maryam Valapour, Lauren E Bartlett, Travis Hee Wai, Christopher H Goss, Joseph M Pilewski, Albert Faro, Joshua M Diamond> ;Journal of Cystic Fibrosis. 2022 Sep 1
• 2 citations
  Culture and Imaging of Human Nasal Epithelial Organoids.
  Zhongyu Liu, Justin D Anderson, Jennifer Natt, Jennifer S Guimbellot> ;Journal of Visualized Experiments. 2021 Dec 17
• 9 citations
  Ivacaftor-elexacaftor-tezacaftor and tacrolimus combination in cystic fibrosis.
  Megan Smith, Kevin J. Ryan, Hector H. Gutierrez, Luz Helena Gutierrez Sanchez, Janaina Nogueira Anderson, Edward P. Acosta, Kim W. Benner, Jennifer S. Guimbellot> ;Journal of Cystic Fibrosis. 2021 Jun 12
• 15 citations
  CFTR function and clinical response to modulators parallel nasal epithelial organoid swelling.
  Justin D. Anderson, Zhongyu Liu, L Victoria Odom, Latona Kersh, Jennifer S. Guimbellot> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 May 19
• 4 citations
  Combination CFTR modulator therapy in children and adults with cystic fibrosis.
  Jennifer S. Guimbellot, Jennifer L. Taylor-Cousar> ;The Lancet. Respiratory Medicine. 2021 May 6
• 31 citations
  Long term clinical effectiveness of ivacaftor in people with the G551D CFTR mutation.
  Jennifer S. Guimbellot, Arthur Baines, Alex C Paynter, Sonya L. Heltshe, Jill M. VanDalfsen, Manu Jain, Steven M. Rowe, Scott D. Sagel, GOAL-e Investigators> ;Journal of Cystic Fibrosis. 2021 Mar 1
• 3 citations
  Highlights from the 2019 North American Cystic Fibrosis Conference.
  Jordana E. Hoppe, Jennifer S. Guimbellot, Stacey L. Martiniano, Demet Toprak, Chelsea S Davis, Cori L. Daines, Marianne S. Muhlebach, Charles R. Esther, Elisabeth P. D...> ;Pediatric Pulmonology. 2020 Sep 1
• 32 citations
  Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis.
  Zhongyu Liu, Justin D. Anderson, Lily Deng, Stephen Mackay, Johnathan Bailey, Latona Kersh, Steven M. Rowe, Jennifer S. Guimbellot> ;Genes. 2020 May 29
• 16 citations
  Variable cellular ivacaftor concentrations in people with cystic fibrosis on modulator therapy.
  Jennifer S. Guimbellot, Kevin J. Ryan, Justin D. Anderson, Zhongyu Liu, Latona Kersh, Charles R. Esther, Steven M. Rowe, Edward P. Acosta> ;Journal of Cystic Fibrosis. 2020 Feb 7
• 25 citations
  Females with Cystic Fibrosis Demonstrate a Differential Response Profile to Ivacaftor Compared with Males.
  Katharine Secunda, Jennifer S. Guimbellot, Borko Jovanovic, Sonya L. Heltshe, Scott D. Sagel, Steven M. Rowe, Manu Jain> ;American Journal of Respiratory and Critical Care Medicine. 2020 Apr 15
• 17 citations
  Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging
  Zhongyu Liu, Stephen Mackay, Dylan M. Gordon, Justin D. Anderson, Dustin Haithcock, Charles J. Garson, Guillermo J. Tearney, George M. Solomon, Kapil Pant, Balabhaskar...> ;Biomedical Optics Express. 2019 Oct 1
• 27 citations
  Effectiveness of ivacaftor in cystic fibrosis patients with non-G551D gating mutations
  Jennifer S. Guimbellot, George M. Solomon, Arthur Baines, Sonya L. Heltshe, Jill M. VanDalfsen, Elizabeth Joseloff, Scott D. Sagel, Steven M. Rowe> ;Journal of Cystic Fibrosis. 2019 Jan 1
• 23 citations
  Tracheostomy in children: Epidemiology and clinical outcomes.
  Catherine D. Sanders, Jennifer S. Guimbellot, Marianne S. Muhlebach, Feng-Chang Lin, Peter H. Gilligan, Charles R. Esther> ;Pediatric Pulmonology. 2018 Sep 1
• 5 citations
  Potential pathogenicity of Inquilinus limosus in a pediatric patient with cystic fibrosis.
  Poore Ts, Isabel Virella-Lowell, Jennifer S. Guimbellot> ;Pediatric Pulmonology. 2018 May 23
• 14 citations
  Sensitivity of ivacaftor to drug-drug interactions with rifampin, a cytochrome P450 3A4 inducer.
  Jennifer S. Guimbellot, Edward P. Acosta, Steven M. Rowe> ;Pediatric Pulmonology. 2018 Feb 28
• 32 citations
  Nasospheroids permit measurements of CFTR-dependent fluid transport
  Jennifer S. Guimbellot, Justin M. Leach, Imron G. Chaudhry, Nancy L. Quinney, Susan E. Boyles, Michael Chua, Inmaculada Aban, Ilona Jaspers, Martina Gentzsch> ;JCI Insight. 2017 Nov 16
• 28 citations
  Toward inclusive therapy with CFTR modulators: Progress and challenges.
  Jennifer S. Guimbellot, Jyoti Sharma, Steven M. Rowe> ;Pediatric Pulmonology. 2017 Sep 7
• 60 citations
  Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
  Jennifer S. Guimbellot, Stephen W. Erickson, Tapan Mehta, Hui Wen, Grier P. Page, Eric J. Sorscher, Jeong S. Hong> ;BMC Medical Genomics. 2009 Mar 25
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Journal Articles

• Sensitivity of ivacaftor to drug-drug interactions with rifampin, a cytochrome P450 3A4 inducer  
  Guimbellot JS, Acosta E, Rowe SM, Pediatr Pulmonol., 1/1/2018
• Toward Inclusive Therapy with CFTR Modulators: Progress and Challenges  
  Guimbellot JS, Sharma J, Rowe SM, Pediatr Pulmonol., 1/1/2017
• Novel measures of CFTR-dependent fluid transport in a three-dimensional nasal epithelial model  
  Guimbellot JS, Aban I, Leach JM, Chaudry IG, Quinney N, Chua M, Jaspers I, Gentzsch M, JCI Insight., 1/1/2017
• EWS/FLI function varies in different cellular backgrounds  
  Zwerner JP, Guimbellot J, May WA., Exp Cell Res, 1/1./2003
• Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines  
  Varga K, Jurkuvenaite A, Wakefield J, Hong JS, Guimbellot JS, Venglarik CJ, Niraj A, Mazur M, Sorscher EJ, Collawn JF, Bebok Z., J Biol Chem, 1/21/2004
• Role of Oxygen in Cystic Fibrosis Transmembrane Conductance Regulator Expression and Function  
  Guimbellot JS, Fortenberry JA, Siegal GP, Moore B, Wen H, Venglarik C, Chen YF, Oparil S, Sorscher EJ, Hong JS, Am J Respir Cell Mol Biol., 1/12/2008
• Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis  
  Guimbellot JS, Erickson SW, Mehta T, Wen H, Page GP, Sorscher EJ, Hong JS., BMC Med Genomics., 1/25/2009
• Effectiveness of ivacaftor in non-G551D gating mutations  
  Guimbellot JS*, Solomon GM*, Baines A, Heltshe SL, VanDalfsen J, Joseloff E, Sagel S, Rowe SM., J Cyst Fibros, 1/20/2018
• Potential pathogenicity of Inquilinus limosus in a pediatric patient with cystic fibrosis  
  Poore TS, Virella-Lowell I, Guimbellot JS., Pediatr Pulmonol., 1/23/2018
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Abstracts/Posters

• Lung on a Chip: The Functional Characterization of Mucociliary Clearance Using Micro Optical Coherence Tomography (�OCT).
  Mackay S, Gordon D, Liu Z, Fortinberry HK, Rosano J, PrabhakarPandian B, Rowe SM, Guimbellot JS, Pulmonary and Critical Care Update, Birmingham, AL, 1/1/2017
• Sodium butyrate mediated enhancement of F508 CFTR expression involves altered protein degradation.
  Guimbellot JS, Varga K, Collawn JF, Sorscher EJ and Bebok Z, Eastern-Atlantic Student Research Forum, Miami, FL, 1/1/2004
• Evidence for acquired defects in CFTR transcription and function caused by hypoxia.
  Guimbellot JS., Moore, B., Wen, H., Venglarik, C., Sorscher, E.J., and Hong, J.S., European Respiratory Society Fourth Lung Science Conference, Taormina, Sicily, Italy, 1/23/2006
• DNA methylation and histone acetylation contribute to transcriptional regulation of CFTR in response to hypoxia.
  Guimbellot JS, Fortenberry JA, Siegal G, Chen Y-F, Oparil S, Sorscher EJ, and Hong JS., North American Cystic Fibrosis Conference, Pediatr Pulmonol Suppl., Baltimore, MD, 1/20/2005
• Effect of ozone on CFTR and HIF expression and function.
  Guimbellot JS,Fortenberry JA, Rowe S, Ballinger C, Postlethwait E, Sorscher EJ., North American Cystic Fibrosis Conference, Pediatr Pulmonol Suppl., Denver, CO, 1/2./2006
• Correlation of microRNA levels and predicted target mRNAs in hypoxia.
  Guimbellot JS, Erickson SW, Wen H, Page GP, Sorscher EJ, Hong JS, American Society of Clinical Investigation /American Physician Scientists Association Annual Meeting, North American Cystic Fibrosis Conference, Pediatr Pulmonol Suppl., Anaheim, CA, 2007; Chicago, IL, 2007, 1/3./2007
• A mouse model of cystic fibrosis has a different protein composition of the pulmonary epithelial lining fluid compared to wild type counterparts.
  Guimbellot JS, Asmellash SG, Bowersock GJ, Ballinger CA, Fortenberry J, Ramos H, Qi RJ, Shambaugh JD, Postlethwait EM, Sorscher EJ, Mobley J., North American Cystic Fibrosis Conference, Pediatr Pulmonol Suppl., Orlando, FL, 1/23/2008
• Role of PRKRA in the development of isolated microtia
  Guimbellot JS, Pyle LC, Spencer EG, Johnson KR, Callens T, Vasconez L, Vasconez H, Engels B, Fix J, Robin N, Messiaen L., American Society of Human Genetics, Philadelphia, PA, 1/11/2008
• Risk factors for pneumothorax in VLBW infants
  Guimbellot JS and Bateman DB, Children�s Hospital of New York Presbyterian Research Day, New York, NY, 1/16/2011
• Primary Ciliary Dyskinesia and Cri du Chat Syndrome: A Genetic Connection
  Guimbellot JS, Shapiro AJ, Weck KE, Chao K, Zariwala MA, Rosenfeld M, Maranda B, Knowles MR, Leigh MW, American Thoracic Society International Meeting, San Diego, CA, 1/16/2014
• Increase in Pseudomonas Infection in Children Undergoing Tracheotomy.
  Guimbellot JS, Reilly CA, Kerr A, Gilligan PH, Muhlebach MS, Esther CR, American Thoracic Society International Meeting, San Diego, CA, 1/16/2014
• Novel measures of CFTR-dependent fluid transport in nasospheroids, a three-dimensional primary ex vivo nasal epithelial model.
  Guimbellot JS, Aban I, Leach JM, Chaudry IG, Quinney NO, Boyles SE, Chua M, Jaspers I, Gentzsch M., Cystic Fibrosis Foundation Research Conference, North American Cystic Fibrosis Conference, Stevenson, WA, 2017; Indianapolis, IN, 2017, 1/1./2017
• Microfluidics airway model measures mucociliary transport apparatus.
  Mackay S, Liu Z, Fortinberry HK, Solomon GM, Gordon D, Garson C, Haithcock D, Ramsey D, Tearney G, Pant K, Pandian P, Rowe SM, Guimbellot JS., North American Cystic Fibrosis Conference, Indianapolis, IN, 1/1./2017
• Sweat gland cultures for the study of cystic fibrosis.
  Guimbellot JS, Mackay S, Liu Z, Joseph D, Bebok Z, Rowe SM, McNicholas-Bevensee CM., North American Cystic Fibrosis Conference, Indianapolis, IN, 1/1./2017
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Lectures

• Novel approaches to predict CFTR modulator efficacy in cystic fibrosis 
  1/1/2018
• Cystic Fibrosis Modulators 
  1/1/2017
• Novel models for predicting CFTR modulator efficacy in cystic fibrosis 
  1/1/2017
• Novel models for predicting CFTR modulator efficacy in cystic fibrosis. 
  Birmingham, AL - 1/1/2017
• Cystic Fibrosis 
  1/1/2016
• Mechanics of breathing 
  1/1/2015
• Disorders of the Chest Wall 
  1/1/2014
• Pulmonary considerations in Children with Neuromuscular diseases 
  1/1/2013
• Environmental and Food Allergies in Children 
  1/1/2012
• Sleep Disordered Breathing 
  1/1/2011
• Care of the NICU graduate 
  1/1/2011
• Role of oxygen sensing in CFTR expression and function 
  St. Louis, MO, 2004; University of Alabama at Birmingham, 2004; Galveston, Texas, 2005 - 1/1/2005
• Epidemiology of tracheostomy Infections. 
  University of North Carolina, Chapel Hill, NC. - 1/14/2013
• Influence of bacteria on F508del CFTR correction by VX-809. 
  Atlanta, GA - 1/10/2014
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