JoelGelernterMD

PubMed

• Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits.
  Marco Galimberti, Daniel F Levey, Joseph D Deak, Hang Zhou, Murray B Stein, Joel Gelernter> ;Molecular Psychiatry. 2024 Apr 5
• A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals.
  Mariela V Jennings, José Jaime Martínez-Magaña, Natasia S Courchesne-Krak, Renata B Cupertino, Laura Vilar-Ribó, Sevim B Bianchi, Alexander S Hatoum, Elizabeth G Atkin...> ;Ebiomedicine. 2024 Apr 2
• A multi-ancestry genetic study of pain intensity in 598,339 veterans.
  Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joel Gelernter,...> ;Nature Medicine. 2024 Mar 1
• Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression.
  Ruoyu Tian, Tian Ge, Hyeokmoon Kweon, Daniel B Rocha, Max Lam, Jimmy Z Liu, Kritika Singh, , Daniel F Levey, Joel Gelernter, Murray B Stein, Ellen A Tsai, Hailiang Hua...> ;Nature Communications. 2024 Feb 26
• Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders.
  Koller, D., Friligkou, E., Stiltner, B., Pathak, G., Løkhammer, S., Levey, D., Zhou, H., Hatoum, A., Deak, J., Kember, R., Treur, J., Johnson, E., Polimanti, R., Kranz...> ;Molecular Psychiatry. 2024 Feb 15
• Genetic and non-genetic predictors of risk for opioid dependence.
  Peter J Na, Joseph D Deak, Henry R Kranzler, Robert H Pietrzak, Joel Gelernter> ;Psychological Medicine. 2024 Feb 6
• Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders.
  Koller, D., Mitjans, M., Kouakou, M., Friligkou, E., Cabrera-Mendoza, B., Deak, J., Llonga, N., Pathak, G., Stiltner, B., Løkhammer, S., Levey, D., Zhou, H., Hatoum, A...> ;Psychiatry Research. 2024 Mar 1
• Polygenic risk for suicide attempt is associated with lifetime suicide attempt in US soldiers independent of parental risk.
  Stein, M., Jain, S., Papini, S., Campbell-Sills, L., Choi, K., Martis, B., Sun, X., He, F., Ware, E., Naifeh, J., Aliaga, P., Ge, T., , , , , Smoller, J., Gelernter, J...> ;Journal of Affective Disorders. 2024 Apr 15
• Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking.
  Johnson, E., Austin-Zimmerman, I., Thorpe, H., Levey, D., Baranger, D., Colbert, S., Demontis, D., Khokhar, J., Davis, L., Edenberg, H., Sanchez-Roige, S., Agrawal, A....> ;Medrxiv. 2024 Jan 18
• A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology.
  Gupta, P., Galimberti, M., Liu, Y., Beck, S., Adhikari, K., , Levey, D., Wingo, A., Wingo, T., Stein, M., Gelernter, J.> ;Medrxiv. 2024 Jan 17
• Correction: Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge.
  Tamman, A., Koller, D., Nagamatsu, S., Cabrera-Mendoza, B., Montalvo-Ortiz, J., Polimanti, R., Pietrzak, R., Abdallah, C., Krystal, J., Gelernter, J.> ;Neuropsychopharmacology. 2024 Mar 1
• 1 citations
  Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.
  Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, Daniel F Levey, Dora Koller, Gita A Pathak, Nastassja Koen, Kuang Lin, Mark J Adams, Miguel E Rentería, Yanzhe Fen...> ;Nature Genetics. 2024 Feb 1
• Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals.
  Gelernter, J., Icick, R., Shadrin, A., Holen, B., Karadag, N., Parker, N., O'Connell, K., Frei, O., Bahrami, S., Høegh, M., Lagerberg, T., Cheng, W., Seibert, T., Djur...> ;Research Square. 2023 Dec 22
• 5 citations
  Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
  Zhou, H., Kember, R., Deak, J., Xu, H., Toikumo, S., Yuan, K., Lind, P., Farajzadeh, L., Wang, L., Hatoum, A., Johnson, J., Lee, H., Mallard, T., Xu, J., Johnston, K.,...> ;Nature Medicine. 2023 Dec 1
• 7 citations
  Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.
  Daniel F Levey, Marco Galimberti, Joseph D Deak, Frank R Wendt, Arjun Bhattacharya, Dora Koller, Kelly M Harrington, Rachel Quaden, Emma C Johnson, Priya Gupta, Mahant...> ;Nature Genetics. 2023 Dec 1
• Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene x Environment Effects and Moderated Mediation.
  Henry Kranzler, Christal Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Ariadni Oikonomou, Damaris Silva-Lopez, Isabel Burton, Morgan Dixon, Jackson Milone, Sarah Ra...> ;Research Square. 2023 Oct 27
• Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene X Environment Effects and Moderated Mediation.
  Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Ariadni Oikonomou, Damaris Silva-Lopez, Isabel Burton, Morgan Dixon, Jackson Milone, Sara...> ;Medrxiv. 2023 Oct 25
• Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge.
  Amanda J F Tamman, Dora Koller, Brenda Cabrera-Mendoza, Chadi Abdallah, John H Krystal, Joel Gelernter, Janitza L Montalvo-Ortiz, Renato Polimanti, Robert H Pietrzak, ...> ;Neuropsychopharmacology. 2024 Mar 1
• 12 citations
  GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
  Anna R Docherty, Niamh Mullins, Allison E Ashley-Koch, Xuejun Qin, Jonathan R I Coleman, Andrey Shabalin, JooEun Kang, Balasz Murnyak, Frank Wendt, Mark Adams, Adrian ...> ;The American Journal of Psychiatry. 2023 Oct 1
• 1 citations
  Genetic Decomposition of the Heritable Component of Reported Childhood Maltreatment.
  Abigail R Ter Kuile, Christopher Hübel, Rosa Cheesman, Jonathan R I Coleman, Alicia J Peel, Daniel F Levey, Murray B Stein, Joel Gelernter, Christopher Rayner, Thalia ...> ;Biological Psychiatry Global Open Science. 2023 Oct 1
• 2 citations
  Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration.
  Isabelle Austin-Zimmerman, Daniel F Levey, Olga Giannakopoulou, Joseph D Deak, Marco Galimberti, Keyrun Adhikari, Hang Zhou, Spiros Denaxas, Haritz Irizar, Karoline Ku...> ;Nature Communications. 2023 Sep 28
• Loneliness and depression: bidirectional mendelian randomization analyses using data from three large genome-wide association studies.
  David A Sbarra, Ferris A Ramadan, Karmel W Choi, Jorien L Treur, Daniel F Levey, Robyn E Wootton, Murray B Stein, Joel Gelernter, Yann C Klimentidis> ;Molecular Psychiatry. 2023 Nov 1
• Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders.
  Wenqianglong Li, Hang Zhou, Johan H Thygesen, Mathis Heydtmann, Iain Smith, Franziska Degenhardt, Markus Nöthen, Marsha Y Morgan, Henry R Kranzler, Joel Gelernter, Nic...> ;Psychiatric Genetics. 2023 Dec 1
• 2 citations
  Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
  Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum,...> ;Medrxiv. 2023 Sep 18
• Positive personality traits moderate persistent high alcohol consumption, determined by polygenic risk in U.S. military veterans: results from a 10-year, population-ba...
  Peter Na, Hang Zhou, Janitza L Montalvo-Ortiz, Brenda Cabrera-Mendoza, Ismene L Petrakis, John H Krystal, Renato Polimanti, Joel Gelernter, Robert H Pietrzak> ;Psychological Medicine. 2023 Dec 1
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Journal Articles

• Methylation in OTX2 and Related Genes, Maltreatment, and Depression in Children  
  James Hudziak, Joan Kaufman, Eric J Nestler, Joel Gelernter, Robert Althoff, Stewart Mostofsky, Nature
• Genome‐Wide Association Meta‐Analysis of Age at First Cannabis Use  
  Henry R Kranzler, Joel Gelernter, Tamara L Wall, Addiction
• AUDIT‐C and ICD Codes as Phenotypes for Harmful Alcohol Use: Association with ADH1B Polymorphisms in Two U.S. Populations  
  David A Fiellin, William C Becker, Joel Gelernter, Henry R Kranzler, Ning Sun, John Concato, Addiction
• Translational Studies Support a Role for Serotonin 2B Receptor (HTR2B) Gene in Aggression-Related Cannabis Response  
  Kerry J Ressler, Joel Gelernter, Henry R Kranzler, Lindsay A Farrer, Nature
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