LorrianaELeardMD

Critical Care Medicine, Lung Transplantation Medicine, Pleural Disease, Thoracic Oncology

Professor of Clinical Medicine, Vice Chief, Clinical Operations, UCSF Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine

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Office
505 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-353-4145
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Education & Training

University of California (San Francisco) School of MedicineFellowship, Lung Transplantation, 2005 - 2006
University of California (San Francisco)Fellowship, Pulmonary Disease and Critical Care Medicine, 2002 - 2005
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1998 - 2001
University of California San Diego School of MedicineClass of 1998

Certifications & Licensure

CA State Medical License 2002 - 2026
TX State Medical License 1999 - 2002
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Publications & Presentations

PubMed

1 citations
Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression.
Daniel R Calabrese, Christina A Ekstrand, Shivaram Yellamilli, Jonathan P Singer, Steven R Hays, Lorriana E Leard, Rupal J Shah, Aida Venado, Nicholas A Kolaitis, Alys...> ;The Journal of Heart and Lung Transplantation. 2024 Feb 15
CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury.
Jesse Santos, Ping Wang, Avishai Shemesh, Fengchun Liu, Tasha Tsao, Oscar A Aguilar, Simon J Cleary, Jonathan P Singer, Ying Gao, Steven R Hays, Jeffrey A Golden, Lorr...> ;JCI Insight. 2023 Nov 8
1 citations
Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis.
Jesse Santos, Steven R Hays, Jeffrey A Golden, Daniel R Calabrese, Nicholas Kolaitis, Mary Ellen Kleinhenz, Rupal Shah, Aida Venado Estrada, Lorriana E Leard, Jasleen ...> ;Transplantation Direct. 2023 Sep 1
4 citations
Development of the Lung Transplant Frailty Scale (LT-FS).
Jonathan P Singer, Jason D Christie, Joshua M Diamond, Michaela A Anderson, Luke A Benvenuto, Ying Gao, Selim M Arcasoy, David J Lederer, Daniel Calabrese, Ping Wang, ...> ;The Journal of Heart and Lung Transplantation. 2023 Jul 1
1 citations
Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.
Anobel Y Odisho, Andrew W Liu, Ali R Maiorano, M Olivia A Bigazzi, Eli Medina, Lorriana E Leard, Rupal Shah, Aida Venado, Alyssa Perez, Jeffrey Golden, Mary Ellen Klei...> ;The Journal of Heart and Lung Transplantation. 2023 Jun 1
6 citations
CD16natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction.
Daniel R Calabrese, Tiffany Chong, Jonathan P Singer, Raja Rajalingam, Steven R Hays, Jasleen Kukreja, Lorriana Leard, Jeffrey A Golden, Lewis L Lanier, John R Greenland> ;American Journal of Transplantation. 2023 Jan 1
2 citations
NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.
Daniel R Calabrese, Tasha Tsao, Mélia Magnen, Colin Valet, Ying Gao, Beñat Mallavia, Jennifer J Tian, Emily A Aminian, Kristin M Wang, Avishai Shemesh, Elman B Punzala...> ;JCI Insight. 2022 Dec 22
3 citations
The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision.
Nicholas A Kolaitis, Hubert Chen, Daniel R Calabrese, Kerry Kumar, Jill Obata, Carrie Bach, Jeffrey A Golden, Marc A Simon, Jasleen Kukreja, Steven R Hays, Lorriana E ...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Feb 1
2 citations
Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.
Nicholas A Kolaitis, Ying Gao, Allison Soong, John R Greenland, Steven R Hays, Jeffrey A Golden, Aida Venado, Lorriana E Leard, Rupal J Shah, Mary Ellen Kleinhenz, Pat...> ;Thorax. 2022 Sep 1
2 citations
Inflammation on bronchoalveolar lavage cytology is associated with decreased chronic lung allograft dysfunction-free survival.
Nancy Y Greenland, Fred Deiter, Daniel R Calabrese, Steven R Hays, Jasleen Kukreja, Lorriana E Leard, Nicholas A Kolaitis, Jeffrey A Golden, Jonathan P Singer, John R ...> ;Clinical Transplantation. 2022 Jun 1
1 citations
Response to selection of lung transplant candidates: A pediatric perspective on the ISHLT consensus document.
Melinda Solomon, Brigitte W M Willemse, Kathleen J Ramos, Lorriana E Leard> ;The Journal of Heart and Lung Transplantation. 2022 Jul 1
1 citations
A survey of use of mTOR inhibitors in patients with lymphangioleiomyomatosis listed for lung transplant.
Krishnan Warrior, Lorriana E Leard, Arun R Nair, Cynthia J Gries, Andrew J Fisher, Simon R Johnson, Francis X McCormack, Daniel F Dilling> ;Respiratory Medicine. 2022 Mar 4
What's in a name: the importance of lung transplant at Cystic Fibrosis Foundation Accredited Care Centers for patients with Cystic Fibrosis
A. Perez, Lorriana E. Leard> ;The Journal of Heart and Lung Transplantation. 2021 Dec 1
1 citations
Perceptions Around Lung Transplant-Associated Hypogammaglobulinemia.
Joey Lew, Megan Casey, Lorriana E. Leard, Steven R. Hays, Iris M. Otani> ;Journal of Clinical Immunology. 2021 Aug 5
224 citations
Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.
Lorriana E. Leard, Are Martin Holm, Maryam Valapour, Allan R. Glanville, Sandeep Attawar, Meghan Aversa, Silvia Vidal Campos, Lillian M. Christon, Marcelo Cypel, Göran...> ;The Journal of Heart and Lung Transplantation. 2021 Jul 24
4 citations
The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation
C.L. DeBolt, Ying Gao, N. Sutter, Allison Soong, Lorriana E. Leard, J.A. Golden, Mary Ellen Kleinhenz, Daniel R Calabrese, John R. Greenland, Aida Venado, Steven R. Ha...> ;Clinical Transplantation. 2021 Mar 7
11 citations
Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates
J. Maheshwari, Nicholas A. Kolaitis, Michaela R. Anderson, Luke Benvenuto, Ying Gao, Patricia P. Katz, John R. Greenland, Paul J. Wolters, Kenneth E. Covinsky, Steven ...> ;Annals of the American Thoracic Society. 2021 Sep 1
2 citations
Lung transplantation from swimming pool drowning victims: A case series.
Sarah Tsou, Joy Chen, Marek Brzezinski, Steven R. Hays, Lorriana E. Leard, Jonathan P. Singer, B. Trinh, Jasleen Kukreja> ;American Journal of Transplantation. 2021 Jan 28
10 citations
Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction.
Daniel T. Dugger, Daniel R Calabrese, Ying Gao, Fred Deiter, Tasha Tsao, J. Maheshwari, Steven R. Hays, Lorriana E. Leard, Mary Ellen Kleinhenz, Rupal J. Shah, Jeffrey...> ;Frontiers in Immunology. 2021 Oct 7
23 citations
Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature
Daniel T. Dugger, Monica Fung, Steven R. Hays, Jonathan P. Singer, M. Kleinhenz, Lorriana E. Leard, Jeffrey A. Golden, Rupal J. Shah, Joyce S. Lee, Fred Deiter, Nancy ...> ;American Journal of Transplantation. 2021 Jan 1
19 citations
Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction.
Carlo J. Iasella, Aki Hoji, Iulia Popescu, Jianxin Wei, Mark E. Snyder, Yingze Zhang, Wei Xu, Vera Iouchmanov, R. Koshy, M. Brown, Monica Fung, Charles Langelier, Eliz...> ;American Journal of Transplantation. 2021 Jun 1
4 citations
Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.
Nicholas A. Kolaitis, Ying Gao, Allison Soong, John R. Greenland, Steven R. Hays, Jeffrey A. Golden, Lorriana E. Leard, Rupal J. Shah, Mary Ellen Kleinhenz, Patricia P...> ;American Journal of Transplantation. 2021 Feb 1
11 citations
Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection
Daniel T. Dugger, Monica Fung, Lorna Zlock, Saharai Caldera, Louis Z. Sharp, Steven R. Hays, Jonathan P. Singer, Lorriana E. Leard, Jefferey A. Golden, Rupal J. Shah, ...> ;Cell Reports. Medicine. 2020 Jul 21
20 citations
Frailty after lung transplantation is associated with impaired health-related quality of life and mortality
Aida Venado, Nicholas A. Kolaitis, Chiung Yu Huang, Ying Gao, David V. Glidden, Allison Soong, N. Sutter, Patricia P. Katz, John R. Greenland, Daniel R Calabrese, Stev...> ;Thorax. 2020 Aug 1
9 citations
Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis
A. Perez, Steven R. Hays, Allison Soong, Ying Gao, John R. Greenland, Lorriana E. Leard, Rupal J. Shah, Jeffrey A. Golden, Jasleen Kukreja, Aida Venado, Mary Ellen Kle...> ;Pediatric Pulmonology. 2020 Apr 1
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