PrescottG.WoodruffMD

Pulmonology • San Francisco, CA

Critical Care Medicine, Pleural Disease

Professor, Medicine, UCSF School of Medicine

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Office
505 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-476-9456

Fax+1 415-502-7814
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Education & Training

University of California (San Francisco)/FresnoFellowship, Pulmonary Disease and Critical Care Medicine, 2002
Massachusetts General HospitalResidency, Internal Medicine, 1993 - 1996
Columbia University Vagelos College of Physicians and SurgeonsClass of 1993

Certifications & Licensure

CA State Medical License 1998 - 2025
MA State Medical License 1996 - 1999
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 2012

Clinical Trials

Zileuton to Treat Adults With Chronic Obstructive Pulmonary Disease (The LEUKO Study) Start of enrollment: 2007 Mar 01
Terminated
Phase 3
Chitinases and Transforming Growth Factor Beta (TGFB) in Human Asthma Start of enrollment: 2010 Feb 01
Completed
Role of microRNAs in T Cell-Driven Inflammation in Asthma Start of enrollment: 2012 Jan 01
Completed
Not Applicable
Study of COPD Subgroups and Biomarkers Start of enrollment: 2010 Nov 01
Active, not recruiting
Study of the Inflammation and Airway Changes That Occur After Exposure to Allergen in Asthmatics Start of enrollment: 2015 Mar 01
Completed
Phase 2
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI Start of enrollment: 2020 Jun 28
Completed
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Publications & Presentations

PubMed

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Carl A Melbourne, Chiara Batini, Katherine A Fawcett, Kijoung Song, Phuwanat Sako...> ;Nature Genetics. 2024 Apr 19
Air Pollution Exposure and Interstitial Lung Features in SPIROMICS Participants with COPD.
Nicolas A Baddour, Laura M Paulin, Amanda J Gassett, Han Woo, Eric A Hoffman, John D Newell Jr, Prescott G Woodruff, Cheryl S Pirozzi, Igor Barjaktarevic, R Graham Bar...> ;Annals of the American Thoracic Society. 2024 Apr 3
Vessel and Airway Characteristics in One-Year CT-defined Rapid Emphysema Progression: SPIROMICS.
Sarah E Gerard, Timothy M Dougherty, Prashant Nagpal, Dakai Jin, MeiLan K Han, John D Newell Jr, Punam K Saha, Alejandro P Comellas, Christopher B Cooper, David Couper...> ;Annals of the American Thoracic Society. 2024 Mar 26
The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort.
Rajat Suri, Daniela Markovic, Han Woo, Mehrdad Arjomandi, R Graham Barr, Russell P Bowler, Gerard Criner, Jeffrey L Curtis, Mark T Dransfield, M Bradley Drummond, Spyr...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Mar 20
Airway tree caliber heterogeneity and airflow obstruction among older adults.
Vameghestahbanati, M., Kingdom, L., Hoffman, E., Kirby, M., Allen, N., Angelini, E., Bertoni, A., Hamid, Q., Hogg, J., Jacobs, D., Laine, A., Maltais, F., Michos, E., ...> ;Journal of Applied Physiology. 2024 Feb 29
Demographic and Clinical Factors Associated With SARS-CoV-2 Spike 1 Antibody Response Among Vaccinated US Adults: the C4R Study.
Kim, J., Sun, Y., Balte, P., Cushman, M., Boyle, R., Tracy, R., Styer, L., Bell, T., Anderson, M., Allen, N., Schreiner, P., Bowler, R., Schwartz, D., Lee, J., Xanthak...> ;Nature Communications. 2024 Feb 19
1 citations
Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma.
Brendan K Huang, Brett M Elicker, Travis S Henry, Kimberly G Kallianos, Lewis D Hahn, Monica Tang, Franklin Heng, Charles E McCulloch, Nirav R Bhakta, Sharmila Majumda...> ;JCI Insight. 2024 Feb 8
Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in COPD.
Opron, K., Begley, L., Erb-Downward, J., Li, G., Alexis, N., Barjaktarevic, I., Barr, R., Bleecker, E., Boucher, R., Bowler, R., Christenson, S., Comellas, A., Criner,...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 23
A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma.
Leung, C., Tang, M., Huang, B., Fain, S., Hoffman, E., Choi, J., Dunican, E., Mauger, D., Denlinger, L., Jarjour, N., Israel, E., Levy, B., Wenzel, S., Sumino, K., Has...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 19
Lung Structure and Risk of Sleep Apnea in SPIROMICS.
Abigail L Koch, Tracie L Shing, Andrew Namen, David Couper, Benjamin Smith, R Graham Barr, Surya Bhatt, Nirupama Putcha, Aaron Baugh, Amit K Saha, Michelle Ziedler, Al...> ;Chronic Obstructive Pulmonary Diseases. 2024 Jan 25
1 citations
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
Jason A Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, Xia Gao, Eugene Kim, Nathan West, Aditi Qamra, Diana Chang, Arindam Chakrabarti, Davi...> ;Iscience. 2023 Oct 20
1 citations
An essential role for miR-15/16 in Treg suppression and restriction of proliferation.
Kristina Johansson, John D Gagnon, Simon K Zhou, Marlys S Fassett, Andrew W Schroeder, Robin Kageyama, Rodriel A Bautista, Hewlett Pham, Prescott G Woodruff, K Mark Ansel> ;Cell Reports. 2023 Oct 31
2 citations
Genetic analyses of chr11p15.5 region identify-associated with asthma-related phenotypes.
Kaminski, N., Xingnan Li, Huashi Li, Stephanie A Christenson, Mario Castro, Loren C Denlinger, Serpil C Erzurum, John V Fahy, Benjamin M Gaston, Elliot Israel, Nizar N...> ;The Journal of Asthma. 2023 Oct 1
1 citations
Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19.
Lucile P A Neyton, Ravi K Patel, Aartik Sarma, , Andrew Willmore, Sidney C Haller, Kirsten N Kangelaris, Walter L Eckalbar, David J Erle, Matthew F Krummel, Carolyn M ...> ;Research Square. 2023 Aug 3
1 citations
Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry.
William McKleroy, Tracie Shing, Wayne H Anderson, Mehrdad Arjomandi, Hira Anees Awan, Igor Barjaktarevic, R Graham Barr, Eugene R Bleecker, John Boscardin, Russell P B...> ;JAMA. 2023 Aug 1
1 citations
Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR.
Nadia N Hansel, Han Woo, Kirsten Koehler, Amanda Gassett, Laura M Paulin, Neil E Alexis, Nirupama Putcha, Wendy Lorizio, Ashraf Fawzy, Daniel Belz, Coralynn Sack, R Gr...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Nov 15
3 citations
Changes in Lung Volumes with Spirometric Disease Progression in COPD.
Bhatt, S. P., Mehrdad Arjomandi, Siyang Zeng, Jianhong Chen, Surya P Bhatt, Fereidoun Abtin, Igor Barjaktarevic, R Graham Barr, Eugene R Bleecker, Russell G Buhr, Gera...> ;Chronic Obstructive Pulmonary Diseases. 2023 Jul 26
Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease.
Amin Motahari, R Graham Barr, MeiLan K Han, Wayne H Anderson, Igor Barjaktarevic, Eugene R Bleecker, Alejandro P Comellas, Christopher B Cooper, David J Couper, Nadia ...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Sep 15
Systemic Markers of Lung Function and Forced Expiratory Volume in 1 Second Decline across Diverse Cohorts.
Debby Ngo, Katherine A Pratte, Claudia Flexeder, Hans Petersen, Hong Dang, Yanlin Ma, Michelle J Keyes, Yan Gao, Shuliang Deng, Bennet D Peterson, Laurie A Farrell, Vi...> ;Annals of the American Thoracic Society. 2023 Aug 1
5 citations
Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans.
Elsa D Angelini, Jie Yang, Pallavi P Balte, Eric A Hoffman, Ani W Manichaikul, Yifei Sun, Wei Shen, John H M Austin, Norrina B Allen, Eugene R Bleecker, Russell Bowler...> ;Thorax. 2023 Nov 1
A blood and bronchoalveolar lavage protein signature of rapid FEVdecline in smoking-associated COPD.
Katarina M DiLillo, Katy C Norman, Christine M Freeman, Stephanie A Christenson, Neil E Alexis, Wayne H Anderson, Igor Z Barjaktarevic, R Graham Barr, Alejandro P Come...> ;Scientific Reports. 2023 May 22
Impact of Marijuana Smoking on COPD Progression in a Cohort of Middle-Aged and Older Persons.
Igor Barjaktarevic, Christopher B Cooper, Tracie Shing, Russell G Buhr, Eric A Hoffman, Prescott G Woodruff, M Bradley Drummond, Richard E Kanner, MeiLan K Han, Nadia ...> ;Chronic Obstructive Pulmonary Diseases. 2023 Jul 26
Impact of Bronchiectasis on COPD Severity and Alpha-1 Antitrypsin Deficiency as a Risk Factor in Individuals with a Heavy Smoking History.
Manuel Izquierdo, Chad R Marion, Frank Genese, John D Newell, Wanda K O'Neal, Xingnan Li, Gregory A Hawkins, Igor Barjaktarevic, R Graham Barr, Stephanie Christenson, ...> ;Chronic Obstructive Pulmonary Diseases. 2023 Jul 26
Spirometry in Mixed-Race Civil War Veterans.
Aaron D Baugh, Prescott Woodruff, Stephen Shiboski, David V Glidden, Victor E Ortega, Neeta Thakur> ;Annals of the American Thoracic Society. 2023 Aug 1
African American race is associated with worse sleep quality in heavy smokers.
Aaron D Baugh, Megan Acho, Abraham Arhin, Igor Barjaktarevic, David Couper, Gerard Criner, Meilan Han, Nadia Hansel, Jerry Krishnan, Katherine Malcolm, Andrew Namen, S...> ;Journal of Clinical Sleep Medicine. 2023 Aug 1
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Press Mentions

PRE-PROOF Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation PRE-PROOFJanuary 4th, 2023
About 20-40% of Adults with COPD Symptoms, but Who Have Not Been Diagnosed with COPD, Use These Types of Long-Term InhalersSeptember 5th, 2022
Bronchodilators Do Not Improve Smoking-Related Respiratory Symptoms in People Without COPDSeptember 4th, 2022
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Grant Support

Spiriomics Clinical CenterNational Heart, Lung, And Blood Institute2011
Role Of TH2 And Non-Th2 Inflammation In Airway Smooth Muscle Remodeling In AsthmaNational Heart, Lung, And Blood Institute2009–2011
Molecular Phenotyping Of AsthmaNational Heart, Lung, And Blood Institute2008–2011
Spiromics Clinical CenterNational Heart, Lung, And Blood Institute2010
Spiriomics Clinical CenterNational Heart, Lung, And Blood Institute2010
Spiromics Clinical CenterDivision Of Lung Diseases2009
Mechanisms Of Smooth Muscle Hyperreactivity On AsthmaNational Center For Research Resources2002–2006

Hospital Affiliations

UCSF Medical CenterSan Francisco, California
Zuckerberg San Francisco General Hospital and Trauma CenterSan Francisco, California