JonathanDanielMorenoMDPhD

PubMed

• Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation.
  Zhu W, Mazzanti A, Voelker TL, Hou P, Moreno JD, Angsutararux P, Naegle KM, Priori SG, Silva JR> ;Circulation research.
• The Combination of Tricuspid Annular Plane Systolic Excursion and HeartMate Risk Score Predicts Right Ventricular Failure After Left Ventricular Assist Device Implanta...
  Raymer DS, Moreno JD, Sintek MA, Nassif ME, Sparrow CT, Adamo L, Novak EL, LaRue SJ, Vader JM> ;ASAIO journal (American Society for Artificial Internal Organs : 1992). 2018-04-26
• Mechanisms and models of cardiac sodium channel inactivation.
  Mangold KE, Brumback BD, Angsutararux P, Voelker TL, Zhu W, Kang PW, Moreno JD, Silva JR> ;Channels (Austin). 2017 Nov 2
• {"__content__"=>"Regulation of Na channel inactivation by the DIII and DIV voltage-sensing domains.", "sup"=>{"__content__"=>"+"}}
  Hsu EJ, Zhu W, Schubert AR, Voelker T, Varga Z, Silva JR> ;The Journal of general physiology. 2017-02-23
• Reply from Pei-Chi Yang, Jonathan D. Moreno, Mao-Tsuen Jeng, Xander H. T. Wehrens, Sergei Noskov and Colleen E. Clancy.
  Yang PC, Moreno JD, Jeng MT, Wehrens XH, Noskov S, Clancy CE> ;J Physiol. 2016 Nov 01
• Parameterization for In-Silico Modeling of Ion Channel Interactions with Drugs.
  Moreno JD, Lewis TJ, Clancy CE> ;PLoS One. 2016
• In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia.
  Yang PC, Moreno JD, Miyake CY, Vaughn-Behrens SB, Jeng MT, Grandi E, Wehrens XH, Noskov SY, Clancy CE> ;J Physiol. 2016 Feb 01
• Ranolazine for congenital and acquired late INa-linked arrhythmias: in silico pharmacological screening.
  Moreno JD, Yang PC, Bankston JR, Grandi E, Bers DM, Kass RS, Clancy CE> ;Circ Res. 2013 Sep 13
• Computational approaches to understand cardiac electrophysiology and arrhythmias.
  Roberts BN, Yang PC, Behrens SB, Moreno JD, Clancy CE> ;Am J Physiol Heart Circ Physiol. 2012 Oct 01
• Pathophysiology of the cardiac late Na current and its potential as a drug target.
  Moreno JD, Clancy CE> ;J Mol Cell Cardiol. 2012 Mar
• A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms.
  Moreno JD, Zhu ZI, Yang PC, Bankston JR, Jeng MT, Kang C, Wang L, Bayer JD, Christini DJ, Trayanova NA, Ripplinger CM, Kass RS, Clancy CE> ;Sci Transl Med. 2011 Aug 31
• Using computational modeling to predict arrhythmogenesis and antiarrhythmic therapy.
  Moreno JD, Clancy CE> ;Drug Discov Today Dis Models. 2009 Fall
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Journal Articles

• Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia  
  Yang, PC; Moreno, JD; Jeng, MT, Noskov, S; and Clancy, CE. Response to Wiliams et al, J Physiol, 1/1/2016
• Ranolazine for congenital and acquired late INa linked arrhythmias: in silico pharmacologic screening  
  Moreno, JD; Yang, PC; Bankston, JR; Grandi, E; Bers, DM; Kass, RS; Clancy, CE, Circ Res, 1/1/2013
• Pathophysiology of the cardiac late Na current and its potential as a drug target  
  Moreno, JD; Clancy, CE, Journal of Molecular and Cellular Cardiology, 1/1/2012
• A multiscale model to predict the effects of class I antiarrhythmic drugs on ventricular rhythms  
  Moreno, JD; Zhu, ZI; Yang, PC; Bankston, JR; Jeng, MT; Kang, C; Wang, L; Ripplinger, CM; Christini, DC; Kass, RS; Clancy, CE, Science Translational Medicine, 1/1/2011
• Cardiac Dynamics In-Silico: Pharmacological Targeting of Long QT3 Syndrome  
  Moreno, JD; Bankston, JR; Kass, RS; Clancy, CE, Biophys J, 1/1/2010
• Using computational modeling to predict arrhythmogenesis and antiarrhythmic therapy  
  Moreno, JD; Clancy, CE, Drug Discovery Today: Disease Models, 1/1/2010
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Books/Book Chapters

• Cardiac Intensive Care 
  Chapter: Right Ventricular Infarction 
  Moreno, JD, and Brown, DLEditors: Brown, DL..ElsevierEdition 3,
• Encyclopedia of Computational Neuroscience. 
  Chapter: Cardiac Excitable Tissue Pathology (Ion Channels). 
  Moreno, JD; Roberts BN; Clancy CEEditors: SpringerReference.com.2013

Abstracts/Posters

• A multiscale model to predict antiarrhythmic drug effects on cardiac rhythms.
  Moreno, JD; Zhu, ZI; Yang, PC; Bankston, JR; Jeng, MT; Kang, C; Wang, L; Christini, DJ; Ripplinger, CM; Kass, RS; Clancy, CE, Gordon Research Conference, “Cardiac Arrhythmia Mechanisms”, Galveston, TX, 1/1/2011
• Using a Human-Centered Design Approach to Develop and Implement User-Centric Performance Support Tools for Hypertension control in Sub-Saharan Africa.
  Vedanthan, R; Marwah, V; Moreno, JD; Sachs, S; Pronyk, P; Fuster, VF, 4th NIH Conference on Dissemination and Implementation Research, Washington, DC, 1/1/2011
• A multiscale model to predict antiarrhythmic drug effects on cardiac rhythms.
  Moreno, JD; Zhu, ZI; Yang, PC; Bankston, JR; Jeng, MT; Kang, C; Wang, L; Christini, DJ; Ripplinger, CM; Kass, RS; Clancy, CE, Medical Student Research Day, Weill Cornell Medical College, 1/1/2011

Lectures

• Pulmonary Artery Pulsatility Index predicts RV failure, duration of inotropes and death after LVAD implantation in a large, high acuity cohort. 
  San Diego, CA - 1/1/2017
• Antiarrhythmic implications of ranolazine. 
  Ventura, CA - 1/1/2013
• Prediction of the emergent effects of drugs on cardiac electrical activity: an in silico approach. 
  Washington University, St. Louis, MO - 1/1/2013
• The Heart-to-Heart Community Outreach Campaign: A community-based participatory research study to assess the prevalence of cardiovascular disease in underserved New Yo... 
  Weill Cornell Medical College - 1/1/2012
• Heart Disease: Knowing your risk and tips for prevention. 
  1/1/2012
• Cardiac Dyanmics in silico: Pharmacology through High Performance Computing. 
  Weill Cornell Medical College - 1/1/2011
• Cardiac Dynamics in-silico: Pharmacological Targeting of Long QT3 Syndrome. 
  San Francisco, CA - 1/1/2010
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Other

• Insured Need Not Apply. 
  Moreno, JD; Patel, SH, Cornell Daily Sun’s “What’s Up Doc?” opinion section
  1/18/2010
• Volunteer Brigades in the Fight Against CVD. 
  Moreno, JD; Patel, SH, Cornell Daily Sun’s “What’s Up Doc?” opinion section
  1/10/2010
• Synergistic effects of combined elicitation on the accumulation of taxanes in Taxus cell suspension cultures. An Honors Research Thesis 
  Moreno JD
  Commonwealth College, University of Massachusetts, Amherst - 1/1/2006