Jonathan Moreno, MD, Cardiology, Saint Louis, MO, Barnes-Jewish Hospital

JonathanDanielMorenoMDPhD

Cardiology Saint Louis, MO

Heart Failure & Transplantation

Division of Cardiology | Department of Medicine; Washington University in St. Louis; E: jmoreno@wustl.edu | W: jonathanmoreno.com

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Office Address

Summary

  • I am a phyisican scientist at Washington University in St. Louis. I have completed my clinical fellowship in cardiovascular disease, and will specialize in heart failure and cardiac transplant. I am currently pursuing my post-doctoral research in the laboratory of Jon Silva, PhD (Biomedical Engineering, Wash U.).

    My research interests include computational modeling of drug / ion channel interactions, inherited cardiomyopathies, and prediction of pharmacotherapy.

Skills & Expertise

  • Echocardiography, Cardiac critical care, Inherited cardiomyopathies, Cardiology, Cardiac arrhythmias, Mathematical modeling, Drug development, Computational biology, Internal medicine, Channelopathies

Education & Training

  • Washington UniversityWashington UniversityPostDoctoralFellowship
  • Washington University - Barnes-Jewish HospitalWashington University - Barnes-Jewish HospitalFellowship
  • Washington University - Barnes-Jewish HospitalWashington University - Barnes-Jewish HospitalFellowship
  • Washington University - Barnes-Jewish HospitalWashington University - Barnes-Jewish HospitalResidency
  • Weill Cornell Medical College of Cornell UniversityWeill Cornell Medical College of Cornell UniversityMedicalSchool
  • Weill Cornell Medical College of Cornell UniversityOtherTraining
  • University of Massachusetts, AmherstOtherTraining
  • University of Massachusetts, AmherstOtherTraining

Certifications & Licensure

  • MO State Medical LicenseMO State Medical License 2014 - 2021
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Cardiovascular Disease
  • Diplomate of the National Board of EchocardiographyAdult Comprehensive Echocardiography

Awards, Honors, & Recognition

  • Burton E. Sobel Award for Excellence in Cardiovascular Research Washington University in St. Louis, 2019
  • Knowlton Incentive for Excellence Award Barnes Jewish Hospital Foundation, 2017
  • Gregory J. Gurtner, MD Internal Medicine Residency Research Award Washington University, St. Louis, 2014
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Publications & Presentations

  • Journal Articles
  • Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia  Yang, PC; Moreno, JD; Jeng, MT, Noskov, S; and Clancy, CE. Response to Wiliams et al, J Physiol, 1/1/2016
  • Ranolazine for congenital and acquired late INa linked arrhythmias: in silico pharmacologic screening  Moreno, JD; Yang, PC; Bankston, JR; Grandi, E; Bers, DM; Kass, RS; Clancy, CE, Circ Res, 1/1/2013
  • Pathophysiology of the cardiac late Na current and its potential as a drug target  Moreno, JD; Clancy, CE, Journal of Molecular and Cellular Cardiology, 1/1/2012
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  • Title
  • Cardiac Intensive Care Chapter: Right Ventricular Infarction 
    Moreno, JD, and Brown, DL
    Editors: Brown, DL..Elsevier
    Edition 3,
  • Encyclopedia of Computational Neuroscience. Chapter: Cardiac Excitable Tissue Pathology (Ion Channels). 
    Moreno, JD; Roberts BN; Clancy CE
    Editors: SpringerReference.com.
    2013
  • Abstracts/Posters
  • A multiscale model to predict antiarrhythmic drug effects on cardiac rhythms. Moreno, JD; Zhu, ZI; Yang, PC; Bankston, JR; Jeng, MT; Kang, C; Wang, L; Christini, DJ; Ripplinger, CM; Kass, RS; Clancy, CE, Gordon Research Conference, “Cardiac Arrhythmia Mechanisms”, Galveston, TX, 1/1/2011
  • Using a Human-Centered Design Approach to Develop and Implement User-Centric Performance Support Tools for Hypertension control in Sub-Saharan Africa. Vedanthan, R; Marwah, V; Moreno, JD; Sachs, S; Pronyk, P; Fuster, VF, 4th NIH Conference on Dissemination and Implementation Research, Washington, DC, 1/1/2011
  • A multiscale model to predict antiarrhythmic drug effects on cardiac rhythms. Moreno, JD; Zhu, ZI; Yang, PC; Bankston, JR; Jeng, MT; Kang, C; Wang, L; Christini, DJ; Ripplinger, CM; Kass, RS; Clancy, CE, Medical Student Research Day, Weill Cornell Medical College, 1/1/2011
  • Lectures
  • Pulmonary Artery Pulsatility Index predicts RV failure, duration of inotropes and death after LVAD implantation in a large, high acuity cohort. San Diego, CA - 1/1/2017
  • Antiarrhythmic implications of ranolazine. Ventura, CA - 1/1/2013
  • Prediction of the emergent effects of drugs on cardiac electrical activity: an in silico approach. Washington University, St. Louis, MO - 1/1/2013
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  • Other
  • Insured Need Not Apply. Moreno, JD; Patel, SH, Cornell Daily Sun’s “What’s Up Doc?” opinion section
    1/18/2010
  • Volunteer Brigades in the Fight Against CVD. Moreno, JD; Patel, SH, Cornell Daily Sun’s “What’s Up Doc?” opinion section
    1/10/2010
  • Synergistic effects of combined elicitation on the accumulation of taxanes in Taxus cell suspension cultures. An Honors Research Thesis Moreno JD
    Commonwealth College, University of Massachusetts, Amherst - 1/1/2006

Press Mentions

  • President Gutmann Kicks off 15th World Congress of BioethicsJune 21, 2020
  • Nuremberg Code Addresses Experimentation, Not VaccinesJune 08, 2020
  • Inside America’s Mask Crunch: A Slow Government Reaction and an Industry Wary of LiabilityApril 03, 2020
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Grant Support

  • Effects of Mechanical Forces on Cardiac Excitability in Heart Disease2018 CIMED Pilot and Feasibility Award2018–Present
  • Development of a cloud-based, in-silico drug testing system for the treatment of cardiac arrhythmiaAmazon Web Services (AWS): Cloud credits for research2018–2019

Research History

  • Cardiovascular Disease Initiative, UN Millennium Villages ProjectCardiovascular disease (CVD) is the second leading cause of death in Africa, and the leading cause of death in those aged 45 or older. This initiative developed a framework for CVD prevention, which acts on a population level as well as an individual level, in a resource-poor setting.2008 - 2011
  • PhD Research, Colleen Clancy, PhD (mentor)My thesis research focused on using experimental function and clinical data to build a theoretical framework to simulate measured properties of drug channel interactions to make predictions about emergent effects of antiarrhythmic drugs on cardiac cells and tissues.2008 - 2011
  • Commonwealth Honors College Research Fellowship and Undergraduate Thesis WorkPaclitaxel is a novel anticancer agent used to treat breast, lung, ovarian, and Kaposi’s sarcoma. My senior thesis studied the effects of adding chemical elicitors to plant cell culture as a way of upregulating the accumulation of both paclitaxel and precursor taxanes in cell culture.2003 - 2006

Professional Memberships

Hospital Affiliations