Philip Dormitzer, MD

Philip Dormitzer, MD, PhD

Internal Medicine Cambridge, MA

Head of US Research, Global Head of Virology, Vice President, Novartis Vaccines; Hospitalist, Coastal Medical Assoc.


Office Address

  • 350 Massachusetts Ave.
    Novartis Vaccines and Diagnostics
    Cambridge, MA 02139
    Phone: (617) 871-5750

Philip Dormitzer, MD, PhD

Internal Medicine Cambridge, MA

Head of US Research, Global Head of Virology, Vice President, Novartis Vaccines; Hospitalist, Coastal Medical Assoc.

Summary

  • Philip R. Dormitzer, M.D., Ph.D., is Head of US Research, Global Head of Virology, and Vice President at Novartis Vaccines and Diagnostics in Cambridge, Massachusetts. He is a practicing physician, board certified in Internal Medicine. After studying anthropology at Harvard College and carrying out a field study of the Efe Pygmies in the Ituri Forest of Zaire, Dr. Dormitzer completed his M.D. and Ph.D. degrees at Stanford University. His graduate research focused on rotavirus antigenic structure. Dr. Dormitzer completed house-staff training in Internal Medicine at Massachusetts General Hospital and a fellowship in the Harvard Combined Infectious Diseases Training Program. He conducted his fellowship research in the Laboratory of Molecular Medicine, led by Dr. Stephen Harrison. As an Assistant Professor of Pediatrics at Harvard Medical School, Dr. Dormitzer led a structural virology laboratory. The Dormitzer group and its collaborators determined the structures of the rotavirus neutralization antigens by NMR spectroscopy, X-ray crystallography, and near atomic resolution electron cryomicroscopy. At NV&D, as Senior Project Leader for Viral Vaccine Research, he had responsibility for global vaccine research projects on influenza, RSV, parvovirus B19, and other agents. In 2009, these projects included the research component of the Novartis response to the H1N1v influenza pandemic, supporting the development and licensure of three pandemic influenza vaccines in the most rapid vaccine response in history. As Head of the Viral Advanced Programs Global Team, he coordinated scientific and industrial functions to advance novel viral vaccine projects toward licensure, with a primary focus on an engineered RSV F subunit vaccine candidate, intended for maternal immunization. As Head of Research, US, he leads approximately 80 scientists, most based at the NV&D Cambridge Research Center, in their viral vaccine discovery mission.

Clinical Specialties & Interests

  • Internal Medicine: General Internal Medicine
  • Clinical Interests: Vaccines; Infectious Disease Medicine; Hospitalists; Vaccines; Virology; Hospitalists; Structural Biology; Infectious Disease Medicine

Faculty Appointments & Work History

  • Hospitalist PhysicianCoastal Medical Associates
    Weymouth, MA
    Admits internal medicine patients and provides in-patient medical coverage at South Shore Hospital.
  • Head of US Vaccines Research, Global Head of Virology, Vice PresidentNovartis Vaccines and Diagnostics
    Cambridge, MA
    Leads a team of approximately 80 scientists, most based at the NV&D Cambridge Research Center, in their viral vaccine discovery mission.
  • Head, Viral Advanced Programs Global TeamNovartis Vaccines and Diagnostics
    Cambridge, MA
    Leads a multifunctional team that leads viral vaccine projects through development to licensure. The team's portfolio of vaccine candidates includes respiratory syncytial virus vaccines, cytomegalovirus vaccines, and parvovirus B19 vaccines.
  • Senior Project Leader, Viral Vaccine ResearchNovartis Vaccines and Diagnostics
    Cambridge, MA
    Leads viral vaccine research projects from conception to pre-clinical proof of concept. Portfolio of candidate vaccines includes influenza vaccines, respiratory syncytial virus vaccines, and virus-like particle-based vaccines.
  • Assistant Professor of PediatricsHarvard Medical School and Children's Hospital
    Boston, MA
    Led a structural virology laboratory. With its collaborators, the team determined the structures of the rotavirus neutralization antigens and developed a recoating genetics system to study rotavirus cell entry and neutralization.
  • Hospitalist PhysicianRehabilitation Medical Associates
    Weymouth, MA
    Admitted internal medicine patients and provided in-patient medical coverage at South Shore Hospital in Weymouth, MA, and at Healthcare South in Braintree, MA.
  • Instructor of PediatricsHarvard Medical School and Children's Hospital
    Boston, MA
    Led a structural virology laboratory studying rotavirus

Education & Medical Training

  • Harvard College
  • Harvard Combined Program in Infectious Diseases
  • Massachusetts General HospitalMassachusetts General Hospital
  • Stanford University School of MedicineStanford University School of Medicine
  • Stanford University

Certifications & Licensure

  • MA State Medical LicenseMA State Medical License1996 - 2015
  • American Board of Internal MedicineInternal Medicine, 1997, Current
  • American Board of Internal MedicineInfectious Disease, 1999

Awards, Honors, & Recognition

  • Maxwell Finland Award for scientific excellence during an infectious disease fellowshipMassachusetts Infectious Disease Society, 2000
  • Joseph Garrison Parker Prize for breadth of interest in a pre-medical studentHarvard College, 1986
  • Jacob Wendell Scholar for academic promise based on the record of the freshman yearHarvard College, 1981

Publications & Presentations

PubMed

Books/Book Chapters

  • Virus Taxonomoy. Ninth Report of the International Committee on the Taxonomy of Viruses Chapter: Family Reoviridae Page 541 - 637
    Attoui, H., P.P.C. Mertens, J. Becnel, S. Belaganahalli, M. Bergoin, C.P. Brussaard, J.D. Chappell, M. Ciarlet, M. del Vas, T.S. Dermody, P.R. Dormitzer, R. Duncan, Q....
    Editors: King, A.M.Q., M.J. Adams, E.B. Carstens, and E.J. Lefkowitz.Elsevier Academic Press, London
  • Influenza Vaccines for the Future Chapter: Cell culture-derived influenza vaccines Page 293 - 312
    Dormitzer, P.R.
    Editors: G. Del Giudice and R. Rappuoli.Birkhauser, Basel
    Edition 2nd,
  • The Oxford Textbook of Medicine Chapter: Virus infections causing dirrhoea and vomiting 
    Dormitzer, P., and U. Desselberger
    Editors: Warrell, D., T. Cox, and J. Firth.Oxford University Press, Oxford, U.K.
    Edition 5th,

Other

  • The Antigenicity and Imunogenicity of Rotavirus Outer Capsid Proteins Expressed by Novel Recombinant Herpesvirus Vectors Dormitzer, P.R., Ph.D. Thesis, Program in Cancer Biology, Stanford University
    University Microfilms, Inc., Ann Arbor, MI

Grant Support

  • Synthetic Influenza Vaccine Seeds for Rapid Pandemic ResponseBiomedical Advanced Research and Development Authority
    2010 - Present
  • Manipulating Immunodominance In Influenza HANational Institute Of Allergy And Infectious Diseases
    2011 - 2011
  • Rotavirus Vp4: Structure And FunctionNational Institute Of Allergy And Infectious Diseases
    2003 - 2006
  • Structural Basis For Rotavirus Entry Into CellsNational Institute Of Allergy And Infectious Diseases
    1998 - 2000

Committees

  • Editorial Board, Journal of Virology Member
  • Research Committee, Infectious Diseases Society of America Member 2012 - Present

Professional Memberships"

Hospital Affiliations

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