
Ravi K Amaravadi MD
Hematologic Oncology, Melanoma
Associate Professor, Medicine, Perelman School of Medicine
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3400 Civic Center BlvdFl 23Philadelphia, PA 19104
Phone+1 215-615-5858
Fax+1 215-615-3349
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Education & Training
University of Pennsylvania Health SystemFellowship, Hematology and Medical Oncology, 2003 - 2006
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 2000 - 2003
Johns Hopkins University School of MedicineClass of 2000
Columbia UniversityB.A., Biochemistry, Magna Cum Laude, 1996
Certifications & Licensure
PA State Medical License 2003 - 2026
MA State Medical License 2002 - 2004
American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2012, 2014-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012, 2014-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014-2017
Clinical Trials
- Hydroxychloroquine and Temozolomide in Treating Patients With Metastatic or Unresectable Solid Tumors Start of enrollment: 2008 Jun 01
- Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment Start of enrollment: 2008 Oct 01
- Dose Escalation Safety Study of TL32711 in Adults With Refractory Solid Tumors or Lymphoma Start of enrollment: 2009 Nov 01
Publications & Presentations
PubMed
- DR5 CAR-T cells target melanoma and suppress MDSCs with minimal toxicity.Huaishan Wang, Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang
Molecular Therapy. 2026-03-04 - Outcomes after SRS and Ipilimumab plus Nivolumab for Melanoma Brain Metastases Following Prior Immune Checkpoint Inhibitor or Targeted Therapy.Ian Messing, Lauren Linkowski, Matthew D Riina, Melanie Berger, Jonathan Baron
The Oncologist. 2026-02-15 - Compliance with guidelines and timeliness of sentinel lymph node biopsy for Merkel cell carcinoma treated with Mohs micrographic surgery versus conventional excision a...Mara D Trifoi, Karla Valdes Morales, Daniela Frankel, Stephanie K Lin, Annika M Deitermann
Journal of the American Academy of Dermatology. 2026-02-01
Journal Articles
- Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-Exposure SARS-CoV-2 Prophylaxis Among Health Care WorkersMatthew C Hyman, Ian Frank, Scott E Hensley, Saar Gill, Dan T Vogl, Ivan Maillard, Daria V Babushok, Alexander C Huang, Sunita D Nasta, Jennifer C Walsh, Michael C Mil..., JAMA Internal Medicine
- Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-cell PopulationsZeynep Eroglu, Iman Osman, Theodore S Nowicki, Antoni Ribas, Michael A Davies, Farbod Darvishian, Daniel Y Wang, Douglas B Johnson, Ravi K Amaravadi, Clinical Cancer Research
- Autophagy in malignant transformation and cancer progressionGalluzzi L, Pietrocola1 F, Bravo-San Pedro JM, Amaravadi RK, Cecconi F, Codogno P, Debnath J, Karantza V, Kumar S, Levine B, Maiuri MC, Martin S, Penninger J, Piacen..., EMBO J, 1/1/2015
Books/Book Chapters
Abstracts/Posters
- Mouse models address key concerns about autophagy inhibition for cancer therapy.Amaravadi RK, Debnath J, Cancer Discovery, 1/1/2014
- PUMA: a puzzle piece in chloroquine's antimelanoma activity.Amaravadi RK, Journal of Investigative Dermatology, 1/1/2013
- Efficacy, Safety and Pharmacokinetics of a new formulation of the BRAF inhibitor dabrafenib in combination with the MEK1/2 inhibitor trametinib from Part D of a Phase ...R. Amaravadi, R. Kudchadkar, R. Gonzalez, D. Lawrence, J. Sosman, J.R. Infante, A. Daud, R. F. Kefford, J. Cebon, W. Sharfman, L. Schuchter, P. Boasberg, K. Lewis, K...., J Clin Oncology; American Society of Clinical Oncology annual meeting, 1/1/2013
Authored Content
- SMR 2021: Elevating the Standards for Virtual MeetingsNovember 2021
Press Mentions
Keeping Cancer ConqueredMay 20th, 2025
Penn Medicine, Wistar Institute Get $11.7M NCI Grant to Develop Potential Melanoma TreatmentsSeptember 24th, 2021
Penn Medicine and Wistar Institute Receive $11.7 Million Grant to Treat MelanomaSeptember 24th, 2021
Grant Support
- Resistance mechanisms to autophagy-modulating therapiesUNIVERSITY OF PENNSYLVANIA2022–2027
- SPORE in Skin CancerWISTAR INSTITUTE2021–2026
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