Sajid A Khan MD FACS

Hepatobiliary Surgery, Melanoma, Pancreas, Surgical Oncology (Other than Breast)

Associate Professor of Surgery, Yale University School of Medicine; Chief, Section of Hepato-Pancreato-Biliary & Mixed Tumors; Co-Director of Team Science, Yale Center for Clinical Investigation; Co-Director Hepatic Arterial Infusion Pump Program; Co-Leader Advanced Hepatobiliary Disease

Join to View Full Profile

Yale Surgery - Gastrointestinal/OncologyPO BOX 208062New Haven, CT 06520
Phone+1 203-337-8507
Fax+1 203-330-7461

Summary

Dr. Sajid Khan is a general surgeon specializing in hepatobiliary surgery, melanoma, pancreas, and surgical oncology, based in New Haven, CT. He completed his medical education from SUNY Upstate Medical University and underwent extensive surgical training, including fellowships at University of Chicago and Memorial Sloan Kettering Cancer Center. He serves as Section Chief of Hepato-Pancreato-Biliary and Mixed Tumors, Co-Director of the Hepatic Arterial Pump Program, Co-Leader of Advanced Hepatobiliary Disease, and Co-Director of Team Science at Yale School of Medicine and holds various roles at Yale New Haven Health System, Yale Cancer Center, and Yale School of Medicine. Dr. Khan has published research on surgical oncology, and was recognized as a Regional Top Doctor by Castle Connolly from 2015 to 2025. His clinical expertise encompasses cholangiocarcinoma, liver metastasis, pancreatic cancer, neuroendocrine tumors, gastric cancers, soft tissue sarcomas, and surgical oncology.

Clinical Expertise

Cholangiocarcinoma, Soft tissue sarcomas, Gastrectomy, Surgical oncology (non-breast), Colorectal surgery, Pancreatectomy, Hepatectomy, Genomics, Health outcomes research, Neoplasm staging, Metabolomics, Metastasis, Minimally Invasive Surgical Procedures, RNA

Education & Training

Yale School of ManagementExecutive Program, Emerging Leaders Program, 2019 - 2021
American College of Surgeons, Division of EducationLeadership, Surgeons as Leaders: From Operating Room to Boardroom, 2016 - 2016
University of ChicagoFellowship, Complex General Surgical Oncology, 2010 - 2013
Oregon Health & Science University (OHSU Health)Residency, Surgery, 2007 - 2010
Memorial Sloan Kettering Cancer CenterFellowship, Complex General Surgical Oncology, 2005 - 2007

Certifications & Licensure

OR State Medical License 2009 - Present
CT State Medical License 2013 - 2026
IL State Medical License 2010 - 2014
American Board of Surgery Surgery
American Board of Surgery Complex General Surgical Oncology

Awards, Honors, & Recognition

Regional Top Doctors Castle Connolly, 2014-2025

Publications & Presentations

PubMed

2 citations
GDF15 in the tumor microenvironment: A central mediator of cancer immunometabolism and therapeutic resistance.
Lingeng Lu, Caroline H Johnson, Sajid A Khan, Melinda L Irwin
Cytokine & Growth Factor Reviews. 2026-01-13
Distinct metabolic and genetic alterations in tumors from early-onset versus late-onset colorectal cancer.
Allison Janak, Abhishek Jain, Rolando Garcia-Milian, Oladimeji Aladelokun, Xiaomei Ma
Free Radical Biology & Medicine. 2025-12-01
HOXA13 overexpression is associated with poor prognosis in colorectal liver metastases.
David G Su, Vadim Kurbatov, Xujun Wang, Zhaoshi Zeng, Philip B Paty
Surgical Oncology Insight. 2025-12-01

Press Mentions

Empowering the Physicians That Bridge Patient Care and Biomedical ResearchSeptember 18th, 2025
United by Cancer Research: One Mission. One VoiceMay 28th, 2025
Yale Surgeons to Present at International Surgical Oncology ConferenceMarch 24th, 2025

Grant Support

Role of immune regulation in colorectal cancer chemotherapeutic responseNational Institutes of Health2021–2026
Understanding sex differences in colon cancer metabolismNational Institutes of Health2018–2020