IrvinMModlinMD

General Surgery • New Haven, CT

Physician

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Office
789 Howard Ave
Fitkin Building - 2nd Floor
New Haven, CT 06519
Phone+1 203-785-3207
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Education & Training

University of Cape Town Faculty of MedicineClass of 1968

Certifications & Licensure

CT State Medical License 1984 - 2025

Publications & Presentations

PubMed

Development of a multigenomic liquid biopsy (PROSTest) for prostate cancer in whole blood.
Mark Kidd, Ignat A Drozdov, Martin Boegemann, Jolanta Kunikowska, Anna Malczewska, Christof Bernemann, Srinivas V Koduru, Kambiz Rahbar, Irvin M Modlin, Lisa Bodei> ;The Prostate. 2024 Apr 3
9 citations
A Sensitive, Portable Microfluidic Device for SARS-CoV-2 Detection from Self-Collected Saliva.
Jianing Yang, Mark Kidd, Alan R Nordquist, Stanley D Smith, Cedric Hurth, Irvin M Modlin, Frederic Zenhausern> ;Infectious Disease Reports. 2021 Dec 14
18 citations
A multigenomic liquid biopsy biomarker for neuroendocrine tumor disease outperforms CgA and has surgical and clinical utility.
I. M. Modlin, M. Kidd, Massimo Falconi, P.L. Filosso, A. Frilling, Anna Malczewska, Christos Toumpanakis, Gerlof D. Valk, Karel Pacak, Lisa Bodei, Kjell Öberg> ;Annals of Oncology. 2021 Nov 1
6 citations
A novel liquid biopsy (NETest) identifies paragangliomas and pheochromocytomas with high accuracy.
Karel Pacak, Mark Kidd, Leah Meuter, Irvin M. Modlin> ;Endocrine-Related Cancer. 2021 Sep 1
18 citations
Molecular Genomic Assessment Using a Blood-based mRNA Signature (NETest) is Cost-effective and Predicts Neuroendocrine Tumor Recurrence With 94% Accuracy.
Irvin M. Modlin, Mark Kidd, Andrea Frilling, Massimo Falconi, Pier Luigi Filosso, Anna Malczewska, Alexandra Kitz> ;Annals of Surgery. 2021 Jun 24
18 citations
Early Identification of Residual Disease After Neuroendocrine Tumor Resection Using a Liquid Biopsy Multigenomic mRNA Signature (NETest)
Irvin M. Modlin, Mark Kidd, Kjell Öberg, Massimo Falconi, Pier Luigi Filosso, Andrea Frilling, Anna Malczewska, Ronald R. Salem, Christos Toumpanakis, Faidon-Marios La...> ;Annals of Surgical Oncology. 2021 May 18
ASO Author Reflections: A Genomic Blood Test (NETest) that Informs you if the Patient has a Recurrence at the First Postoperative Visit.
Irvin M. Modlin> ;Annals of Surgical Oncology. 2021 Apr 19
5 citations
A combination of surgery, theranostics, and liquid biopsy - a personalised oncologic approach to treatment of patients with advanced metastatic neuroendocrine neoplasms.
Andrea Frilling, Ashley K Clift, Adam E Frampton, Jamshed Bomanji, Daniel Kaemmerer, Adil Al-Nahhas, Ali Alsafi, Mark Kidd, Irvin M. Modlin, Dieter Hoersch, Richard P....> ;International Journal of Medical Sciences. 2021 Mar 19
19 citations
Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine?
Anja Rinke, Christoph J. Auernhammer, Lisa Bodei, Mark Kidd, Sebastian Krug, Rita T. Lawlor, Ilaria Marinoni, Aurel Perren, Aldo Scarpa, Halfdan Sorbye, Marianne Pavel...> ;Gut. 2021 Mar 10
36 citations
Molecular profiling of neuroendocrine tumours to predict response and toxicity to peptide receptor radionuclide therapy.
Lisa Bodei, Heiko Schöder, Richard P. Baum, Ken Herrmann, Jonathan R. Strosberg, Martyn Caplin, Kjell Öberg, Irvin M. Modlin> ;The Lancet. Oncology. 2020 Sep 1
2 citations
A metastatic tumor is no different to a viral pandemic: lessons learnt from COVID-19 may teach us to change the PRRT paradigm.
Giovanni Paganelli, Lisa Bodei, Irvin M. Modlin> ;European Journal of Nuclear Medicine and Molecular Imaging. 2020 Jun 20
13 citations
Neuroendocrine Tumor Omic Gene Cluster Analysis Amplifies the Prognostic Accuracy of the NETest.
Mark Kidd, Alexandra Kitz, Ignat Drozdov, Irvin M Modlin> ;Neuroendocrinology. 2021 Jan 1
58 citations
PRRT neuroendocrine tumor response monitored using circulating transcript analysis: the NETest.
Lisa Bodei, Mark Kidd, Aviral Singh, Wouter A. van der Zwan, Stefano Severi, Ignat Drozdov, Anna Malczewska, Richard P. Baum, Dik J. Kwekkeboom, Giovanni Paganelli, Er...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2020 Apr 1
56 citations
Neuroendocrine Neoplasms of the Small Bowel and Pancreas.
Ashley K Clift, Mark Kidd, Lisa Bodei, Christos Toumpanakis, Richard P. Baum, Kjell Öberg, Irvin M Modlin, Andrea Frilling> ;Neuroendocrinology. 2020 Jan 1
13 citations
Blood Chromogranin A Is Not Effective as a Biomarker for Diagnosis or Management of Bronchopulmonary Neuroendocrine Tumors/Neoplasms.
Somer Matar, Anna Malczewska, Kjell Öberg, Lisa Bodei, Harry R. Aslanian, Anna Lewczuk-Myślicka, Pier Luigi Filosso, Alejandro L Suarez, Agnieszka Kolasińska-Ćwikła, M...> ;Neuroendocrinology. 2020 Jan 1
22 citations
An Assessment of Circulating Chromogranin A as a Biomarker of Bronchopulmonary Neuroendocrine Neoplasia: A Systematic Review and Meta-Analysis.
Anna Malczewska, Mark Kidd, Somer Matar, Beata Kos-Kudła, Lisa Bodei, Kjell Öberg, Irvin M Modlin> ;Neuroendocrinology. 2020 Jan 1
33 citations
The clinical applications of a multigene liquid biopsy (NETest) in neuroendocrine tumors.
Anna Malczewska, Beata Kos-Kudła, Mark Kidd, Ignat Drozdov, Lisa Bodei, Somer Matar, Kjell Öberg, Irvin M. Modlin> ;Advances in Medical Sciences. 2020 Mar 1
4 citations
The path to the future: Education of nuclear medicine therapeutic specialists as responsible physicians
Lisa Bodei, Arturo Chiti, Irvin M. Modlin, Andrew M. Scott, Heiko Schöder> ;Journal of Nuclear Medicine. 2019 Dec 1
2 citations
The Use of Deep Learning and Neural Networks in Imaging: Welcome to the New Mathematical Milieu of Medicine.
Irvin M Modlin, Mark Kidd, Ignat Drozdov, Lisa Bodei> ;Neuroendocrinology. 2020 Jan 1
Why wait for posterity (or the future) to provide proof to savor the elixir of precision oncology? Read interviews with intellects and dine with the doyens of discovery.
Vikas Prasad, Irvin M. Modlin, Arturo Chiti> ;European Journal of Nuclear Medicine and Molecular Imaging. 2019 Aug 21
14 citations
Utility of a ready-to-use PCR system for neuroendocrine tumor diagnosis.
Mark Kidd, Ignat Drozdov, Somer Matar, Nicole Gurunlian, Nicholas J. Ferranti, Anna Malczewska, Philip Bennett, Lisa Bodei, Irvin M Modlin> ;Plos One. 2019 Jun 27
7 citations
Caveat Emptor: Let Our Acclaim of the Apotheosis of PRRT Not Blind Us to the Error of Prometheus.
Lisa Bodei, Ken Herrmann, Richard P Baum, Mark Kidd, Anna Malczewska, Irvin M Modlin> ;Journal of Nuclear Medicine. 2019 Jan 1
27 citations
Blood mRNA Measurement (NETest) for Neuroendocrine Tumor Diagnosis of Image-Negative Liver Metastatic Disease.
Anna Malczewska, Lisa Bodei, Mark Kidd, Irvin M. Modlin> ;The Journal of Clinical Endocrinology and Metabolism. 2019 Mar 1
74 citations
The NETest: The Clinical Utility of Multigene Blood Analysis in the Diagnosis and Management of Neuroendocrine Tumors.
Irvin M. Modlin, Mark Kidd, Anna Malczewska, Ignat Drozdov, Lisa Bodei, Somer Matar, Kyung-Min Chung> ;Endocrinology and Metabolism Clinics of North America. 2018 Sep 1
24 citations
Measurement of circulating transcript levels (NETest) to detect disease recurrence and improve follow‐up after curative surgical resection of well‐differentiated pancr...
Cansu Guney Genc, Anneke P. J. Jilesen, Els J. M. Nieveen van Dijkum, Heinz-Josef Klümpen, Casper H.J. van Eijck, Ignat Drozdov, Anna Malczewska, Mark Kidd, Irvin M. M...> ;Journal of Surgical Oncology. 2018 Jul 1
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Journal Articles

Blood mRNA Measurement (NETest) for Neuroendocrine Tumors Diagnosis of Image-Negative Liver Metastatic Disease
Irvin M Modlin, Lisa Bodei, The Journal of Clinical Endocrinology and Metabolism

Lectures

A 13-gene colorectal cancer liquid biopsy with greater than 90 percent accuracy in diagnosis and assessment of disease status.
ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/25/2020

Press Mentions

Branford Company’s at-Home Saliva Coronavirus Test Easy, Fast and ConvenientNovember 29th, 2020
Targeting the Engine Room of the Cancer CellJune 19th, 2018
Targeting the Engine Room of the Cancer CellJune 18th, 2018

Grant Support

Molecular Strategies To Define Carcinoids And Rationalize Surgical InterventionNational Cancer Institute2006–2009
Molecular Strategies For Gastric Carcinoid SurgeryNational Cancer Institute2003–2005
Efficacy Of Inhibition Of Gastric Acid Secretion By Intravenous PantoNational Center For Research Resources1999–2000
Secretagogue Regulation In Parietal CellsNational Institute Of Diabetes And Digestive And Kidney Diseases1989–1991

IrvinMModlinMD

Dr. Modlin is on Doximity

Education & Training

Certifications & Licensure

Publications & Presentations

Press Mentions

Grant Support

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