Skip to main content
Steve Goldstein, MD, Pediatrics, Irvine, CA, UCI Health

SteveGoldsteinMDPhD

Pediatrics • Irvine, CA

Pediatric Cardiology

Vice Chancellor, Health Affairs and Distinguished Professor, Pediatrics, Physiology & Biophysics, and Pharmaceutical Sciences

Join to view full profile

Dr. Goldstein is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

  • Connect with other colleagues in the same hospital or clinic
  • Search all U.S. specialist profiles and refer a patient
  • Read the latest clinical news and earn CME/CEU credits

See Dr. Goldstein's full profile

Already have an account?

Summary

  • With over 30 years of experience as a physician-scientist, pediatric cardiologist, and academic administrator, my life’s work is focused on improving the human condition through the best in education, research and care. At the UCI, I am helping to bring this vision to fruition as the Vice Chancellor of Health Affairs, leading the development of the Susan and Henry Samueli College of Health Sciences (SCoHS) and UCI Health, our healthcare system. We are pursuing opportunities to improve the health and well-being of Californians while educating the diverse healthcare workforce of the future, endeavors made possible by our interprofessional college structure and the expansion of our clinical service sites.

    My own work has spanned different systems and responsibilities in academic medicine and higher education. As a leader, I enlist aspirational problem-solvers and team players whose satisfaction derives from helping others succeed; I have found this inspires a spirit of openness and productivity that advances organizational achievement. A career overseeing world-class physicians, open-minded scientists, dedicated educators and selfless administrators has also taught me the importance of balancing guidance with a respect for freedom to operate, optimizing the benefits of assembling exceptional personnel, and the power of transparency, diversity and respect.

    In addition to administrative endeavors, I have maintained a complementary career as a researcher and educator. My laboratory focuses on ion channels, essential proteins in each of our cells that produce heartbeats and other “excitable” membrane phenomena that are fundamental to health and treatment of disease. I am proud of the 60 research trainees who have worked with me and then gone on to exciting careers in academia, industry and service.

    • Dr. Steve Goldstein named UCI vice chancellor for health affairs

    Irvine, Calif., Dec. 18, 2018 - Dr. Steve Goldstein - a nationally renowned academic leader, physician and pediatric researcher - has been named vice chancellor

Education & Training

  • Children's Hospital/Boston Medical Center
    Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1987 - 1988
  • Children's Hospital/Boston Medical Center
    Children's Hospital/Boston Medical CenterInternship, Pediatrics, 1986 - 1987
  • Harvard Medical School
    Harvard Medical SchoolClass of 1986, MD
  • Harvard University
    Harvard UniversityPhD, Pathology (Immunology), 1986
  • Brandeis University
    Brandeis UniversityMA, Biochemistry, 1978
  • Brandeis University
    Brandeis UniversityBA, Biochemistry, Magna Cum Laude, 1978
  • Children's Hospital/Boston Medical Center
    Children's Hospital/Boston Medical CenterFellowship, Pediatric Cardiology

Certifications & Licensure

  • MA State Medical License
    MA State Medical License Current
  • CT State Medical License
    CT State Medical License Current
  • CA State Medical License
    CA State Medical License 2020 - 2024
  • IL State Medical License
    IL State Medical License Active through 2023
  • American Board of Pediatrics Pediatrics

Awards, Honors, & Recognition

  • Fellow American Association for the Advancement of Science (AAAS), 2020
  • Pritzker Scholar University of Chicago, 2004-2009
  • E. Mead Johnson Award Society for Pediatric Research, 2001
  • Join now to see all

Publications & Presentations

PubMed

Journal Articles

  • Hypoxia produces pro-arrhythmic late sodium current in cardiac myocytes by SUMOylation of NaV1.5 channels  
    Leigh D. Plant, L.D., Xiong, D., Romero, J., Dai, H. and Steve A. N. Goldstein, Cell Reports, 2/18/2020
  • Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor  
    Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, and Goldstein SAN, Proc. Natl. Acad. Sci. (USA), 11/26/2018
  • SUMOylation of NaV1.2 channels mediate the early response to acute hypoxia in central neurons  
    Plant, L.D., Marks, J.D. and S.A.N. Goldstein, eLife, 12/28/2016
  • Join now to see all

Abstracts/Posters

  • A common cardiac sodium channel variant associated with sudden infant death in African Americans
    Plant, L.D., P.N. Bowers, Q. Liu, T. Morgan, T. Zhang, M.W. State, W. Chen, R.A. Kittles and S.A.N. Goldstein, J. Clin. Invest, 2006
  • Sumoylation silences the plasma membrane leak K+ channel K2P1
    Rajan, S., L., Plant, M.L. Rabin, M.H. Butler, and S.A.N. Goldstein, Cell, 4/8/2005
  • Forward Transport: 14-3-3 binding overcomes dibasic retention in endoplasmic reticulum by dibasic signals
    O'Kelly, I., Butler, M.H., Zilberberg, N. and S.A.N. Goldstein, Cell, 11/15/2002
  • Join now to see all

Authored Content

  • Opinion: Academic health centers play unique role in battle against COVID-19 pandemicApril 2020
  • A doctor’s demanding life here and in IraqJune 2004

Press Mentions

  • Partnership to Unlock the Full Potential of Data to Advance the Science and Practice of Healthcare: Q&A with Syntropy and the University of California, Irvine
    Partnership to Unlock the Full Potential of Data to Advance the Science and Practice of Healthcare: Q&A with Syntropy and the University of California, IrvineOctober 11th, 2021
  • U.S. On Track to Almost Triple Vaccine Output in March, as New Variants Pressure Europe and Brazil
    U.S. On Track to Almost Triple Vaccine Output in March, as New Variants Pressure Europe and BrazilMarch 22nd, 2021
  • UCI to Build World-Class Hospital on Irvine Campus
    UCI to Build World-Class Hospital on Irvine CampusJanuary 22nd, 2021
  • Join now to see all

Committees

  • Member, Association of American Medical Colleges, Medical Center Leaders Caucus 2019 - Present
  • Member, Steering Committee, Association of American Medical Colleges, Group on Diversity and Inclusion 2018 - 2019
  • Member, Association of American Medical Colleges, Liaison Committee on Medical Education Dean’s Group 2018 - 2019
  • Member and Vice-Chair, National Science Foundation Biological Sciences Directorate Advisory Committee 2014 - 2017
  • Scientific Advisor, National Institutes of Health, Roadmap in Nanomedicine 2005 - 2011

Professional Memberships

  • Biophysical Society
    Member
  • Society of General Physiologists
    Member
  • Society Pediatric Research
    Member
  • American Pediatric Society
    Member
  • American College of Healthcare Executives
    Member

Hospital Affiliations

External Links

  • LinkedIn https://www.linkedin.com/in/steveangoldstein/

Dr. Steve Goldstein, Dr. Steve Goldstein, MD, Dr. S Goldstein