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950 Campbell AveMc 111West Haven, CT 06516
Phone+1 203-937-3848
Dr. Samuel is on Doximity
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Education & Training
University of ChicagoFellowship, Endocrinology, Diabetes, and Metabolism, 1998 - 2000- University of ChicagoResidency, Internal Medicine, 1995 - 1998
New York University School of MedicineClass of 1995
Certifications & Licensure
CT State Medical License 2000 - 2026
IL State Medical License 1995 - 2002
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Publications & Presentations
PubMed
- CIDEB and CGI-58 differentially regulate liver lipid-droplet cholesterol to modulate metabolic dysfunction-associated steatohepatitis severity.Ikki Sakuma, Rafael C Gaspar, Henrique N Morgan, Jie Zheng, Ali R Nasiri
Cell Reports. 2026-06-23 - G Protein-Coupled Receptor 17 (Gpr17) Enhances Leptin and Insulin Sensitivity in Lean and Obese Mouse Models.Xun Sun, Connor Mahler, Natalie D Stull, Ali Nasiri, Baohua Zhou
Obesity. 2026-06-01 - 17 citationsLiver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis.Ikki Sakuma, Rafael C Gaspar, Ali R Nasiri, Sylvie Dufour, Mario Kahn
Proceedings of the National Academy of Sciences of the United States of America. 2025-05-06
Journal Articles
- PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed RatsArijeet K Gattu, Varman T Samuel, Violeta Popov, Daniel F Vatner, Gary Cline, Endocrinology
- PKCε Contributes to Lipid-Induced Insulin Resistance Through Cross Talk with p70S6K and Through Previously Unknown Regulators of Insulin SignalingMax C Petersen, Varman T Samuel, Proceedings of the National Academy of Sciences
Press Mentions
Dr. Brian J. Fertig: Exploring Your MetabolismApril 6th, 2022
Grant Support
- Exploring the mechanisms by which dietary fructose primarily impairs white adipose, not hepatic, function: insights from a novel ketohexokinase antisense oligonucleotideVA CONNECTICUT HEALTHCARE SYSTEM2023–2027
- Exploring mitochondrialflux and lipid compartmentation in vivo to develop new therapies for alcoholic liver diseaseYALE UNIVERSITY2022–2025
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