AbhishekChakrabortyMD

Pediatrics • Columbia, MO

Pediatric Critical Care Medicine, Pediatric Cardiac Critical Care

Senior resident

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Office
1616 Kitty Hawk Dr
3
Columbia, MO 65202
Phone+1 573-639-8583
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Education & Training

NRS Medical College CalcuttaClass of 2010

Certifications & Licensure

TN State Medical License 2022 - 2025
PA State Medical License 2019 - 2022
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Cardiology

Publications & Presentations

PubMed

Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression.
Sharifi, N., Liang Qin, Michael Berk, Yoon-Mi Chung, Di Cui, Ziqi Zhu, Abhishek A Chakraborty, Nima Sharifi> ;Cell Reports. 2024 Jan 23
57 citations
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
Matthew G. Oser, Amin H. Sabet, Wenhua Gao, Abhishek A. Chakraborty, Anna C. Schinzel, Rebecca B. Jennings, Raquel Fonseca, Dennis M. Bonal, Matthew A. Booker, Abdalla...> ;Genes & Development. 2019 Dec 1
19 citations
Mutant p53 induces a hypoxia transcriptional program in gastric and esophageal adenocarcinoma
Nilay Sethi, Osamu Kikuchi, James M. McFarland, Yanxi Zhang, Max Chung, Nicholas Kafker, Mirazul Islam, Benjamin L. Lampson, Abhishek A. Chakraborty, William G. Kaelin...> ;JCI Insight. 2019 Aug 16
230 citations
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.
Abhishek A. Chakraborty, Tuomas Laukka, Matti Myllykoski, Alison E. Ringel, Matthew A. Booker, Michael Y. Tolstorukov, Yuzhong Jeff Meng, Sam Meier, Rebecca B. Jenning...> ;Science. 2019 Mar 15
106 citations
Cells Lacking the RB1 Tumor Suppressor Gene are Hyperdependent on Aurora B Kinase for Survival
Matthew G. Oser, Raquel Fonseca, Abhishek A. Chakraborty, Rachel Brough, Alexander Spektor, Rebecca B. Jennings, Abdallah Flaifel, Jesse Novak, Aditi Gulati, Elizabeth...> ;Cancer Discovery. 2019 Feb 1
188 citations
Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma
Samuel K. McBrayer, Jared R. Mayers, Gabriel J. DiNatale, Diana D. Shi, Januka Khanal, Abhishek A. Chakraborty, Kristopher A. Sarosiek, Kimberly J. Briggs, Alissa Robb...> ;Cell. 2018 Sep 20
32 citations
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase
Abhishek A. Chakraborty, Eijiro Nakamura, Jun Qi, Amanda Creech, Jacob D. Jaffe, Joshiawa Paulk, Jesse Novak, Kshithija Nagulapalli, Samuel K. McBrayer, Glenn S. Cowle...> ;Science Translational Medicine. 2017 Jul 12
296 citations
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
Hyejin Cho, Xinlin Du, James P. Rizzi, Ella Liberzon, Abhishek A. Chakraborty, Wenhua Gao, Ingrid Carvo, Sabina Signoretti, Richard K. Bruick, John A. Josey, Wallace E...> ;Nature. 2016 Nov 3
145 citations
pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.
Jianping Guo, Abhishek A. Chakraborty, Pengda Liu, Wenjian Gan, Xingnan Zheng, Hiroyuki Inuzuka, Bin Wang, Jinfang Zhang, Linli Zhang, Min Yuan, Jesse Novak, Jin Q. Ch...> ;Science. 2016 Aug 26
55 citations
Erratum: EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection (Cell (2016) 164 (884-895))
Benjamin A. Olenchock, Javid Moslehi, Alan H. Baik, Shawn M. Davidson, Jeremy Williams, William J. Gibson, Abhishek A. Chakraborty, Kerry A. Pierce, Christine M. Mille...> ;Cell. 2016 Apr 7
54 citations
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.
Benjamin A Olenchock, Javid Moslehi, Alan H Baik, Shawn M Davidson, Jeremy Williams, William J Gibson, Abhishek A Chakraborty, Kerry A Pierce, Christine M Miller, Eric...> ;Cell. 2016 Feb 25
23 citations
A common functional consequence of tumor-derived mutations within c-MYC.
Abhishek A. Chakraborty, Claudio Scuoppo, Soumyadeep Dey, Lance R. Thomas, Shelly L. Lorey, Scott W. Lowe, William P. Tansey> ;Oncogene. 2015 Apr 30
Do changes in the c-MYC coding sequence contribute to tumorigenesis?
Abhishek A. Chakraborty, William P. Tansey> ;Molecular & Cellular Oncology. 2015 Apr 1
99 citations
Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase
Xingnan Zheng, Bo Zhai, Peppi Koivunen, Sandra J. Shin, Gang Lu, Jiayun Liu, Christoph Geisen, Abhishek A. Chakraborty, Javid Moslehi, David M. Smalley, Xin Wei, Xian ...> ;Genes & Development. 2014 Jul 1
10 citations
Inference of cell cycle-dependent proteolysis by laser scanning cytometry
Abhishek A. Chakraborty, William P. Tansey> ;Experimental Cell Research. 2009 Jun 10
26 citations
Adenoviral E1A Function through Myc
Abhishek A. Chakraborty, William P. Tansey> ;Cancer Research. 2009 Jan 1
28 citations
Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc
Kathryn A Tworkowski, Abhishek A. Chakraborty, Andrew V. Samuelson, Yvette R. Seger, Masako Narita, Gregory J. Hannon, Scott W. Lowe, William P. Tansey> ;Proceedings of the National Academy of Sciences of the United States of America. 2008 Apr 22
7 citations
Applications of microarray and bioinformatics tools to dissect molecular responses of the central nervous system to antioxidant micronutrients
Kishorchandra Gohil, Abhishek A. Chakraborty> ;Nutrition. 2004 Jan 1
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Hospital Affiliations

Le Bonheur Children's HospitalMemphis, Tennessee