AdamSamuel Abdur-RahimSperlingMDPhD

PubMed

• Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma.
  Ghobrial, I., Gormley, N., Kumar, S., Mateos, M., Bergsagel, P., Chesi, M., Dhodapkar, M., Dispenzieri, A., Fonseca, R., Getz, G., Kastritis, E., Kristinsson, S., Mart...> ;Blood Cancer Discovery. 2024 Mar 4
• Cellular Mass Response to Therapy Correlates With Clinical Response for a Range of Malignancies.
  Stevens, M., Kimmerling, R., Olcum, S., Vacha, M., LaBella, R., Minnah, A., Katsis, K., Fujii, J., Shaheen, Z., Sundaresan, S., Criscitiello, J., Niesvizky, R., Raje, ...> ;JCO Precision Oncology. 2024 Jan 1
• Clinical Outcomes and Evolution of Clonal Hematopoiesis in Patients with Newly Diagnosed Multiple Myeloma.
  Tarek H Mouhieddine, Chidimma Nzerem, Robert Redd, Andrew Dunford, Matthew Leventhal, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Habib El-Khoury, David P Steensma, ...> ;Cancer Research Communications. 2023 Dec 18
• A safety review of recently approved and emerging drugs for patients with relapsed or refractory multiple myeloma.
  Shonali Midha, Monique A Hartley-Brown, Clifton C Mo, Shahrier Hossain, Omar Nadeem, Elizabeth K O'Donnell, Giada Bianchi, Adam S Sperling, Jacob P Laubach, Paul G Ric...> ;Expert Opinion on Drug Safety. 2023 Nov 28
• 2 citations
  SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
  Chun-Wei Chen, Linda Zhang, Ravi Dutta, Abhishek Niroula, Peter G Miller, Christopher J Gibson, Alexander G Bick, Jaime M Reyes, Yi-Tang Lee, Ayala Tovy, Tianpeng Gu, ...> ;Cell Stem Cell. 2023 Nov 2
• Chimeric Antigen Receptor T Cells in Multiple Myeloma.
  Parth Shah, Adam S Sperling> ;Hematology/oncology Clinics of North America. 2023 Dec 1
• 3 citations
  Selinexor: Targeting a novel pathway in multiple myeloma.
  Clifton C Mo, Andrew J Yee, Shonali Midha, Monique A Hartley-Brown, Omar Nadeem, Elizabeth K O'Donnell, Giada Bianchi, Adam S Sperling, Jacob P Laubach, Paul G Richardson> ;Ejhaem. 2023 Aug 1
• 10 citations
  UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
  Jonathan M Tsai, Jacob D Aguirre, Yen-Der Li, Jared Brown, Vivian Focht, Lukas Kater, Georg Kempf, Brittany Sandoval, Stefan Schmitt, Justine C Rutter, Pius Galli, Col...> ;Molecular Cell. 2023 Aug 3
• Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs.
  Xili Liu, Maria Moscvin, Seungeun Oh, Tianzeng Chen, Wonshik Choi, Benjamin Evans, Sean M Rowell, Omar Nadeem, Clifton C Mo, Adam S Sperling, Kenneth C Anderson, Zahid...> ;Clinical and Experimental Medicine. 2023 Nov 1
• 2 citations
  Clonal Hematopoiesis in Young Women Treated for Breast Cancer.
  Christopher J Gibson, Geoffrey Fell, Tal Sella, Adam S Sperling, Craig Snow, Shoshana M Rosenberg, Greg Kirkner, Ashka Patel, Deborah Dillon, Alexander G Bick, Donna N...> ;Clinical Cancer Research. 2023 Jul 5
• 1 citations
  The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein.
  Charles Zou, Hojong Yoon, Paul M C Park, J J Patten, Jesse Pellman, Jeannie Carreiro, Jonathan M Tsai, Yen-Der Li, Shourya S Roy Burman, Katherine A Donovan, Jessica G...> ;Iscience. 2023 May 19
• 10 citations
  High-dose melphalan treatment significantly increases mutational burden at relapse in multiple myeloma.
  Mehmet Kemal Samur, Marco Roncador, Anil Aktas Samur, Mariateresa Fulciniti, Abdul Hamid Bazarbachi, Raphael Szalat, Masood A Shammas, Adam S Sperling, Paul G Richards...> ;Blood. 2023 Apr 6
• Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk.
  Ram Ajore, Abhishek Niroula, Maroulio Pertesi, Caterina Cafaro, Malte Thodberg, Molly Went, Erik L Bao, Laura Duran-Lozano, Aitzkoa Lopez de Lapuente Portilla, Thorunn...> ;Nature Communications. 2022 Dec 13
• 8 citations
  Clonal hematopoiesis of indeterminate potential and risk of death from COVID-19.
  Peter G Miller, Geoffrey G Fell, Brody H Foy, Allison K Scherer, Christopher J Gibson, Adam S Sperling, Bala B Burugula, Tetsushi Nakao, Md M Uddin, Hailey Warren, Lyn...> ;Blood. 2022 Nov 3
• 52 citations
  Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms.
  Adam S Sperling, Veronica A Guerra, James A Kennedy, Yuanqing Yan, Joanne I Hsu, Feng Wang, Andrew T Nguyen, Peter G Miller, Marie E McConkey, Vanessa A Quevedo Barrio...> ;Blood. 2022 Oct 20
• Repurposing the repurposed: thalidomide analogs as immune stimulants to overcome T cell exhaustion.
  Mikołaj Słabicki, Adam S Sperling> ;Cell Chemical Biology. 2022 Aug 18
• 7 citations
  Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.
  Rob S Sellar, Adam S Sperling, Mikołaj Słabicki, Jessica A Gasser, Marie E McConkey, Katherine A Donovan, Nada Mageed, Dylan N Adams, Charles Zou, Peter G Miller, Ravi...> ;The Journal of Clinical Investigation. 2022 Aug 15
• 12 citations
  Quality of life, psychological distress, and prognostic perceptions in patients with multiple myeloma.
  Elizabeth K O'Donnell, Yael N Shapiro, Andrew J Yee, Omar Nadeem, Bonnie Y Hu, Jacob P Laubach, Andrew R Branagan, Kenneth C Anderson, Clifton C Mo, Nikhil C Munshi, I...> ;Cancer. 2022 May 15
• 5 citations
  The emerging importance and evolving understanding of clonal hematopoiesis in multiple myeloma.
  Christin B DeStefano, Steven J Gibson, Adam S Sperling, Paul G Richardson, Irene Ghobrial, Clifton C Mo> ;Seminars in Oncology. 2022 Feb 1
• 8 citations
  Functional dissection of inherited non-coding variation influencing multiple myeloma risk.
  Ram Ajore, Abhishek Niroula, Maroulio Pertesi, Caterina Cafaro, Malte Thodberg, Molly Went, Erik L Bao, Laura Duran-Lozano, Aitzkoa Lopez de Lapuente Portilla, Thorunn...> ;Nature Communications. 2022 Jan 10
• 9 citations
  Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia.
  Sabrin Tahri, Tarek H. Mouhieddine, Robert A. Redd, Luisa Maria Lampe, Katarina Nillson, Nang Kham Su, Habib El-Khoury, Amin Nassar, Elio Adib, Govind Bindra, Sarah Ab...> ;Blood Advances. 2021 Nov 30
• 2 citations
  Characteristics and Outcomes of Eosinophilic Fasciitis-Associated Monoclonal Gammopathy.
  Daniel R. Mazori, Bina Kassamali, Michelle S. Min, Morgan Schaefer, Avery H. LaChance, Adam S. Sperling, Ruth Ann Vleugels> ;JAMA Dermatology. 2021 Oct 27
• 66 citations
  Association of Clonal Hematopoiesis with Chronic Obstructive Pulmonary Disease.
  Peter Miller, Dandi Qiao, Joselyn Rojas-Quintero, Michael C. Honigberg, Adam S. Sperling, Christopher J. Gibson, Alexander G. Bick, Abhishek Niroula, Marie McConkey, B...> ;Blood. 2021 Sep 10
• 34 citations
  Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy.
  Peter Miller, Adam S. Sperling, Elliott J. Brea, Mark B. Leick, Geoffrey Fell, Max Jan, Satyen H. Gohil, Yu-Tzu Tai, Nikhil C. Munshi, Catherine J. Wu, Donna Neuberg, ...> ;Blood Advances. 2021 Aug 10
• 9 citations
  Facts and Hopes in Multiple Myeloma Immunotherapy.
  Adam S. Sperling, Kenneth C. Anderson> ;Clinical Cancer Research. 2021 Mar 26
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Abstracts/Posters

• Phase II Trial of the Combination of Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma
  Adam S Sperling, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019