AdrianGerardMurphyMD

PubMed

• 3 citations
  A study of using epigenetic modulators to enhance response to pembrolizumab (MK-3475) in microsatellite stable advanced colorectal cancer.
  Marina Baretti, Adrian G Murphy, Marianna Zahurak, Nicole Gianino, Rose Parkinson, Rosalind Walker, Tamara Y Lopez-Vidal, Lei Zheng, Gary Rosner, Nita Ahuja, Schalper ...> ;Clinical Epigenetics. 2023 Apr 29
• 19 citations
  Immune cell atlas of cholangiocarcinomas reveals distinct tumor microenvironments and associated prognoses.
  Tao Xia, Keyu Li, Nan Niu, Yingkuan Shao, Ding Ding, Dwayne L Thomas, Hao Jing, Kenji Fujiwara, Haijie Hu, Arsen Osipov, Chunhui Yuan, Christopher L Wolfgang, Elizabet...> ;Journal of Hematology & Oncology. 2022 Mar 28
• 149 citations
  Final Overall Survival Efficacy Results of Ivosidenib for Patients With Advanced Cholangiocarcinoma With IDH1 Mutation: The Phase 3 Randomized Clinical ClarIDHy Trial.
  Andrew X. Zhu, Teresa Macarulla, Milind Javle, R. Kate Kelley, Sam J. Lubner, Jorge Adeva, James M. Cleary, Daniel V.T. Catenacci, Mitesh J. Borad, John Bridgewater, W...> ;JAMA Oncology. 2021 Nov 1
• 8 citations
  Challenges of the current precision medicine approach for pancreatic cancer: A single institution experience between 2013 and 2017.
  Ding Ding, Ammar A. Javed, Dea Cunningham, Jonathan Teinor, Michael J. Wright, Zunaira N. Javed, Cara Wilt, Lindsay Parish, Mary Hodgin, Amy Ryan, Carol Judkins, Keith...> ;Cancer Letters. 2021 Jan 28
• 1 citations
  Anal Cancer as a First Presentation of a Germline Mutation in TERT.
  Zoe L. Cosner, Mary Armanios, Amy Hacker-Prietz, Adrian Murphy, Amol Narang> ;JCO Oncology Practice. 2020 Nov 4
• 20 citations
  A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer.
  Adrian Murphy, Marianna Zahurak, Mirat Shah, Colin D. Weekes, Aaron R. Hansen, Lillian L. Siu, Anna Spreafico, Noelle K. LoConte, Nicole M. Anders, Tearra Miles, Miche...> ;Clinical and Translational Science. 2020 Nov 1
• 14 citations
  Preclinical mouse models for immunotherapeutic and non-immunotherapeutic drug development for pancreatic ductal adenocarcinoma.
  Mengni He, MacKenzie G. Henderson, Stephen Muth, Adrian Murphy, Lei Zheng> ;Annals of Pancreatic Cancer. 2020 Jul 22
• 449 citations
  Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study
  Ghassan K. Abou-Alfa, Teresa Macarulla, Milind Javle, Robin Kate Kelley, Sam J. Lubner, Jorge Adeva, James M. Cleary, Daniel V.T. Catenacci, Mitesh J. Borad, John Brid...> ;The Lancet. Oncology. 2020 Jun 1
• 729 citations
  Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study
  Ghassan K. Abou-Alfa, Vaibhav Sahai, Antoine Hollebecque, Gina M. Vaccaro, Davide Melisi, Raed Al-Rajabi, Andrew Scott Paulson, Mitesh J. Borad, David Gallinson, Adria...> ;The Lancet. Oncology. 2020 May 1
• 40 citations
  A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer.
  Mark Yarchoan, Chiung Yu Huang, Qingfeng Zhu, Anna Ferguson, Jennifer N. Durham, Robert A. Anders, Elizabeth D. Thompson, Noah Rozich, Dwayne L. Thomas, Julie M. Nauro...> ;Cancer Medicine. 2020 Feb 1
• 135 citations
  Small molecule immunomodulation: the tumor microenvironment and overcoming immune escape.
  Arsen Osipov, May Tun Saung, Lei Zheng, Adrian Murphy> ;Journal for Immunotherapy of Cancer. 2019 Aug 22
• 15 citations
  Sequential short-course radiation therapy and chemotherapy in the neoadjuvant treatment of rectal adenocarcinoma
  Angela Y. Jia, Amol Narang, Bashar Safar, Atif Zaheer, Adrian Murphy, Nilofer S. Azad, Susan L. Gearhart, Sandy H. Fang, Jonathan E. Efron, Tam Warczynski, Amy Hacker-...> ;Radiation Oncology. 2019 Aug 19
• 3 citations
  Readmission Adversely Affects Survival in Surgical Rectal Cancer Patients.
  Sophia Y. Chen, Miloslawa Stem, Susan L. Gearhart, Bashar Safar, Sandy H. Fang, Nilofer S. Azad, Adrian Murphy, Amol Narang, Christopher L. Wolfgang, Jonathan E. Efron> ;World Journal of Surgery. 2019 Oct 1
• 43 citations
  IDO1 inhibition potentiates vaccine-induced immunity against pancreatic adenocarcinoma
  Alex B. Blair, Jennifer Kleponis, Dwayne L. Thomas, Stephen Muth, Adrian Murphy, Victoria M. Kim, Lei Zheng> ;The Journal of Clinical Investigation. 2019 Apr 1
• 44 citations
  From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy.
  Arsen Osipov, Adrian Murphy, Lei Zheng> ;Advances in Cancer Research. 2019 Jan 1
• 3 citations
  Extracellular vesicles as novel therapeutics in hepatic failure.
  Adrian Murphy, Florin M. Selaru> ;Hepatology. 2018 Mar 1
• 14 citations
  Stromal Annexin A2 expression is predictive of decreased survival in pancreatic cancer
  Adrian Murphy, Kelly Foley, Agnieszka A. Rucki, Tao Xia, Elizabeth M. Jaffee, Chiung Yu Huang, Lei Zheng> ;Oncotarget. 2017 Nov 15
• 22 citations
  Immunotherapy as a treatment for biliary tract cancers: A review of approaches with an eye to the future.
  Alex B. Blair, Adrian Murphy> ;Current Problems in Cancer. 2017 Oct 31
• 13 citations
  Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer.
  Bikram Shrestha, Yifei Sun, Farzana A. Faisal, Victoria M. Kim, Kevin C. Soares, Alex B. Blair, Joseph M. Herman, Amol Narang, Avani S. Dholakia, Lauren M. Rosati, Amy...> ;Cancer Medicine. 2017 Jun 21
• 2 citations
  The Evolving Role of Checkpoint Inhibitors in the Management of Gastroesophageal Cancer.
  Adrian Murphy, Ronan J. Kelly> ;Hematology/oncology Clinics of North America. 2017 Jun 1
• 15 citations
  Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer
  Adrian Murphy, Rory Casey, Aoife Maguire, Miriam Tosetto, Clare T. Butler, Emer Conroy, Alison L. Reynolds, Kieran Sheahan, Diarmuid O'Donoghue, William M. Gallagher, ...> ;Scientific Reports. 2016 Oct 14
• 182 citations
  Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade
  Valerie Lee, Adrian Murphy, Dung T. Le, Luis A. Diaz> ;The Oncologist. 2016 Oct 1
• 37 citations
  Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer.
  Lorraine Burke, Clare T. Butler, Adrian Murphy, Bruce Moran, William M. Gallagher, Jacintha O'Sullivan, Breandán N. Kennedy> ;Frontiers in Cell and Developmental Biology. 2016 Sep 21
• 77 citations
  Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation.
  Qian Xiao, Donger Zhou, Agnieszka A. Rucki, Jamila K Williams, Jiaojiao Zhou, Guanglan Mo, Adrian Murphy, Kenji Fujiwara, Jennifer Kleponis, Bulent Salman, Christopher...> ;Cancer Research. 2016 Sep 15
• 51 citations
  The emerging role of immunotherapy in colorectal cancer
  David Lynch, Adrian Murphy> ;Annals of Translational Medicine. 2016 Aug 1
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