
Adrian Vella MD
Diabetes, Lipid Metabolism
Professor, Internal Medicine, Mayo Medical School
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200 1st St SwRochester, MN 55905
Phone+1 507-284-2511
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Education & Training
Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Endocrinology, Diabetes, and Metabolism, 1998 - 2001
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1995 - 1998
University of Malta School of MedicineClass of 1993
University of MaltaBasic Medical Science Training, With Distinction, 1988 - 1990
GF Abela LyceumA-Level Studies, Physics, Chemistry, Biology, Philosophy & Computer Science, 1986 - 1988
Certifications & Licensure
MN State Medical License 1997 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Centricity Enterprise (CE), GE Healthcare, 2014-2017
- CMS Meaningful Use Stage 1 Certification Centricity Patient Online, GE Healthcare, 2014-2017
- CMS Meaningful Use Stage 1 Certification Centricity Enterprise, GE Healthcare, 2014-2017
Clinical Trials
- A Study to Assess the Effects of Vildagliptin on Gastric Emptying in Patients With Type 2 Diabetes Start of enrollment: 2005 May 01
- Incretins in Impaired Fasting Glucose Start of enrollment: 2006 Aug 01
- Genetic Variation in OCT1 and Response to Metformin Start of enrollment: 2010 Jun 01
Publications & Presentations
PubMed
- Integrated glucagon model for estimation of α-cell responsivity to glucose and amino acids during graded glucose infusion.F Boscolo, S Mohan, M C Laurenti, J Kohlenberg, H E Christie
American Journal of Physiology. Endocrinology and Metabolism. 2026-04-01 - 1 citationsHepatic steatosis in humans is associated with preserved glucagon action on amino acid metabolism.Hannah E Christie, Sneha Mohan, Aoife M Egan, Federica Boscolo, Chiara Dalla Man
The Journal of Clinical Investigation. 2026-03-02 - Modeling the effect of glucagon on endogenous glucose production in healthy individuals under meal-like conditions.Edoardo Faggionato, Alessio Tonello, Marcello C Laurenti, Adrian Vella, Chiara Dalla Man
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2025-12-01
Journal Articles
- Hypoglycemia After Gastric Bypass Surgery: Current Concepts and ControversiesTracey McLaughlin, Adrian Vella, The Journal of Clinical Endocrinology and Metabolism
- The Oral Minimal Model MethodCobelli C, Dalla Man C, Toffolo G, Basu R, Vella A, Rizza R, Diabetes, 4/1/2014
- Beta-Cell Function After Weight-Loss Induced by Bariatric SurgeryVella A., Physiology (Bethesda), 3/1/2014
Books/Book Chapters
Abstracts/Posters
- Diabetes-associated genetic variation and GLP-1 secretion and action GLP-1 in non-diabetic subjects.Smushkin G, Dalla Man C, Micheletto F, Sathananthan A, Camilleri M, Cobelli C, Rizza RA, Vella A, Diabetes and Prediabetes, Madrid, 4/1/2011
- Minimal Model indices and genetic biomarkers in the pathogenesis of diabetes.Sambo F, Di Camillo B, Toffolo G, Dalla Man C, Cobelli C, Vella A, Diabetes and Prediabetes, Madrid, 4/1/2011
- The interaction of colesevelam with sitagliptin suggests differential effects on fasting and postprandial glucose metabolism in subjects with type 2 diabetes.Smushkin G, Dalla Man C, Sathananthan M, Cobelli C, Vella A, EASD, 1/1/2011
Press Mentions
Mayo Clinic Study Indicates Rural US Counties Have Higher Diabetes-Related DeathsSeptember 29th, 2022
The #1 Cause of Diabetes, According to PhysiciansJuly 6th, 2022
Children Are up to 2.5 Times More Likely to Develop Diabetes After COVID-19 Infection, Study FindsJanuary 11th, 2022
Grant Support
- The effect of endogenous GLP-1 secretion on islet function in vivoMAYO CLINIC ROCHESTER2020–2030
- The regulation of fasting glucose metabolism in people with and without prediabetesMAYO CLINIC ROCHESTER2007–2029
- Glucagon secretion and action in humansMAYO CLINIC ROCHESTER2017–2027
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