AlanW.HeldmanMD

Cardiology • Miami, FL

Adult Congenital Heart Disease, Interventional Cardiology

Founder - Modern Cardiovascular Technologies

Join to view full profile

Dr. Heldman is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Heldman's full profile

Already have an account?

Office
6619 S Dixie Hwy
#255
Miami, FL 33143
Phone+1 305-928-3999

Fax+1 305-675-3226
Is this information wrong?

Education & Training

Johns Hopkins UniversityFellowship, Cardiovascular Disease, 1991 - 1995
Johns Hopkins UniversityResidency, Internal Medicine, 1988 - 1991
University of Alabama School of MedicineClass of 1988

Certifications & Licensure

MD State Medical License 1993 - 2022
FL State Medical License 2007 - 2020

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
America's Top Doctors Castle Connolly, 2010-2011
Super Doctor SuperDoctors.com

Clinical Trials

Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) Start of enrollment: 2007 Nov 01
Terminated
Phase 1, Phase 2
The Transendocardial Autologous Cells (hMSC or hBMC) in Ischemic Heart Failure Trial (TAC-HFT) Start of enrollment: 2008 Aug 01
Completed
Phase 1, Phase 2

Publications & Presentations

PubMed

19 citations
Genetic determinants of responsiveness to mesenchymal stem cell injections in non-ischemic dilated cardiomyopathy.
Angela C. Rieger, Robert J. Myerburg, Victoria Florea, Makoto Natsumeda, Courtney Premer, Aisha Khan, Ivonne Hernandez Schulman, Mayra Vidro-Casiano, Darcy L. DiFede, ...> ;Ebiomedicine. 2019 Oct 1
22 citations
Alternative access for transcatheter aortic valve replacement in older adults: A collaborative study from France and United States.
Abdulla A. Damluji, Magdalena Murman, Seunghwan Byun, Mauro Moscucci, Jon R. Resar, Rani K. Hasan, Carlos Alfonso, Roger G. Carrillo, Donald Williams, Christopher C. K...> ;Catheterization and Cardiovascular Interventions. 2018 Nov 15
57 citations
A Combination of Allogeneic Stem Cells Promotes Cardiac Regeneration
Makoto Natsumeda, Victoria Florea, Angela C. Rieger, Bryon A. Tompkins, Monisha N. Banerjee, Samuel Golpanian, Julia Fritsch, Ana Marie Landin, Nilesh D. Kashikar, Vas...> ;Journal of the American College of Cardiology. 2017 Nov 14
93 citations
Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Bryon A. Tompkins, Darcy L. DiFede, Aisha Khan, Ana Marie Landin, Ivonne Hernandez Schulman, Marietsy V. Pujol, Alan W. Heldman, Roberto Miki, Pascal J. Goldschmidt-Cl...> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2017 Oct 12
55 citations
Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty
Samuel Golpanian, Darcy L. DiFede, Aisha Khan, Ivonne Hernandez Schulman, Ana Marie Landin, Bryon A. Tompkins, Alan W. Heldman, Roberto Miki, Bradley J. Goldstein, Muz...> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2017 Oct 12
14 citations
Effects of Transendocardial Stem Cell Injection on Ventricular Proarrhythmia in Patients with Ischemic Cardiomyopathy: Results from the POSEIDON and TAC‐HFT Trials
Archana Ramireddy, Chad Brodt, Adam Mendizabal, Darcy L. DiFede, Chris Healy, Vishal Goyal, Yahya Alansari, James O. Coffey, Juan F. Viles-Gonzalez, Alan W. Heldman, J...> ;Stem Cells Translational Medicine. 2017 May 1
232 citations
Randomized Comparison of Allogeneic Versus Autologous Mesenchymal Stem Cells for Nonischemic Dilated Cardiomyopathy: POSEIDON-DCM Trial
Joshua M. Hare, Darcy L. DiFede, Angela C. Rieger, Victoria Florea, Ana Marie Landin, Jill El-Khorazaty, Aisha Khan, Muzammil Mushtaq, Maureen H. Lowery, John J. Byrne...> ;Journal of the American College of Cardiology. 2017 Feb 7
31 citations
Elective or Emergency Use of Mechanical Circulatory Support Devices During Transcatheter Aortic Valve Replacement.
Vikas Singh, Abdulla A. Damluji, Rodrigo Mendirichaga, Carlos Alfonso, Claudia Martinez, Donald Williams, Alan W. Heldman, Eduardo de Marchena, William W. O'Neill, Mau...> ;Journal of Interventional Cardiology. 2016 Oct 1
6 citations
Transient and persistent conduction abnormalities following transcatheter aortic valve replacement with the Edwards-Sapien prosthesis: a comparison between antegrade v...
Solomon J. Sager, Abdulla A. Damluji, Joshua A Cohen, Sachil Shah, Brian P. O'Neill, Carlos Alfonso, Claudia Martinez, Robert J. Myerburg, Alan W. Heldman, Mauricio G....> ;Journal of Interventional Cardiac Electrophysiology. 2016 May 28
26 citations
Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A phase I/II, random...
Samuel Golpanian, Darcy L. DiFede, Marietsy V. Pujol, Maureen H. Lowery, Silvina Levis-Dusseau, Bradley J. Goldstein, Ivonne Hernandez Schulman, Bangon Longsomboon, Ar...> ;Oncotarget. 2016 Feb 25
80 citations
Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease
Samuel Golpanian, Ivonne Hernandez Schulman, Ray F. Ebert, Alan W. Heldman, Darcy L. DiFede, Phillip C. Yang, Joseph C. Wu, Roberto Bolli, Emerson C. Perin, Lemuel A. ...> ;Stem Cells Translational Medicine. 2016 Feb 1
105 citations
Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy.
Vasileios Karantalis, Viky Y. Suncion-Loescher, Luiza Bagno, Samuel Golpanian, Ariel Wolf, Cristina Sanina, Courtney Premer, Anthony J. Kanelidis, Frederic McCall, Bo ...> ;Journal of the American College of Cardiology. 2015 Nov 3
3 citations
Combined Retrograde/Antegrade Approach to Transcatheter Closure of an Aortic Paravalvular Leak
Abdulla A. Damluji, Husnu E. Kaynak, Alan W. Heldman> ;Texas Heart Institute Journal. 2015 Oct 1
7 citations
The story of the lost needle: Foreign body embolization to the heart.
Abhijit Ghatak, Peter Baik, Rhanderson Cardoso, Jonathan Dobrinsky, Husnu E. Kaynak, George R. Marzouka, Robert Brian Stang, Roger G. Carrillo, Donald Williams, Alan W...> ;Journal of Cardiology Cases. 2015 Jun 1
17 citations
Long-term outcomes associated with the transaortic approach to transcatheter Aortic valve replacement.
Joel A. Lardizabal, Conrad Macon, Brian P. O'Neill, Harit Desai, Vikas Singh, Claudia Martinez, Carlos Alfonso, Mauricio G. Cohen, Alan W. Heldman, William W. O'Neill,...> ;Catheterization and Cardiovascular Interventions. 2015 Jun 1
32 citations
Prognostic Value of Serial B-Type Natriuretic Peptide Measurement in Transcatheter Aortic Valve Replacement (from the PARTNER Trial)
Brian P. O'Neill, Mayra Guerrero, Vinod H. Thourani, Susheel Kodali, Alan W. Heldman, Mathew R. Williams, Ke Xu, Augusto D. Pichard, Michael J. Mack, Vasilis Babaliaro...> ;The American Journal of Cardiology. 2015 May 1
1 citations
Multimodality image guidance with Dyna-CT for transcatheter treatment of paravalvular leak of a stentless valve.
Brett Van Leer-Greenberg, Claudia Martinez, Alan W. Heldman> ;Catheterization and Cardiovascular Interventions. 2015 May 1
2 citations
Emergent Percutaneous Biventricular Support during Transcatheter Aortic Valve Replacement.
Vikas Singh, Alan W. Heldman> ;The Journal of Heart Valve Disease. 2015 May 1
4 citations
Management of Transcatheter Aortic Valve Embolization into the Left Ventricle
Lynda Otalvaro, Abdulla A. Damluji, Carlos Alfonso, Donald Williams, Alan W. Heldman> ;Journal of Cardiac Surgery. 2015 Apr 1
31 citations
Rationale and design of the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis in Dilated Cardiomyopathy (the POSEIDON-DCM study): a phase I/II, random...
Muzammil Mushtaq, Darcy L. DiFede, Samuel Golpanian, Aisha Khan, Samirah A. Gomes, Adam Mendizabal, Alan W. Heldman, Joshua M. Hare> ;Journal of Cardiovascular Translational Research. 2014 Oct 30
5 citations
Impact of CMS coverage decision on access to transcatheter aortic valve replacement.
Brian P. O'Neill, William W. O'Neill, Donald Williams, Mauricio G. Cohen, Alan W. Heldman, Conrad Macon, Claudia Martinez, Carlos Alfonso, Pedro Martinez Clark, Omaida...> ;Catheterization and Cardiovascular Interventions. 2014 Jul 1
4 citations
Clinical outcomes with on‐label and off‐label use of the transcatheter heart valve in the United States
Joel A. Lardizabal, Conrad Macon, Brian P. O'Neill, Vikas Singh, Claudia Martinez, Carlos Alfonso, Mauricio G. Cohen, Donald Williams, William W. O'Neill, Alan W. Heldman> ;Catheterization and Cardiovascular Interventions. 2014 Jul 1
31 citations
Optimizing rotational atherectomy in high-risk percutaneous coronary interventions: Insights from the PROTECT ΙΙ study
Mauricio G. Cohen, Abhijit Ghatak, Neal S. Kleiman, Srihari S. Naidu, Joseph M. Massaro, SM Ajay J. Kirtane Md, Jeffrey W. Moses, E. Magnus Ohman, Vladimír Džavík, Igo...> ;Catheterization and Cardiovascular Interventions. 2014 Jun 1
5 citations
Transfemoral Aortic Valve Replacement in Failing Aortic Root Homografts
Lynda Otalvaro, Carlos E. Alfonso, William W. O'Neill, Brian P. O'Neill, Alan W. Heldman> ;Journal of Cardiac Surgery. 2014 May 1
246 citations
Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients undergoing ...
Vasileios Karantalis, Darcy L. DiFede, Gary Gerstenblith, Si M. Pham, James F Symes, Juan P. Zambrano, Joel E. Fishman, Pradip M. Pattany, Ian K. McNiece, John V. Cont...> ;Circulation Research. 2014 Apr 11
Join now to see all

Press Mentions

Health News - Two New Miller School Studies Show How Stem Cell Injections Improve Heart StructureFebruary 10th, 2016

Grant Support

Animal CoreNational Heart, Lung, And Blood Institute2007–2009
Animal CoreNational Heart, Lung, And Blood Institute2005–2006
Women'S Angiographic Vitamins And Estroogens TrialNational Center For Research Resources2000

Hospital Affiliations

University of Miami HospitalMiami, Florida
UMHC-Sylvester Comprehensive Cancer CenterMiami, Florida