AlexChenMD

PubMed

• Aberrant MFN2 transcription facilitates homocysteine-induced VSMCs proliferation via the increased binding of c-Myc to DNMT1 in atherosclerosis.
  Xu, L.,Hao, H.,Hao, Y.,Wei, G.,Li, G.,Ma, P.,Xu, L.,Ding, N.,Ma, S.,Chen, A. F.,Jiang, Y.> ;J. Cell. Mol. Med.. 2019 May 20
• Preeclampsia serum induces human glomerular vascular endothelial cell hyperpermeability via the HMGB1-Caveolin-1 pathway.
  Xu, Q.,Du, F.,Zhang, Y.,Teng, Y.,Tao, M.,Chen, A. F.,Jiang, R.> ;J. Reprod. Immunol.. 2018 Jul 15
• Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation.
  Fu, G. X.,Chen, A. F.,Xu, Q. M.,Han, B. B.,Huang, G. Z.,Zhong, Y.> ;Free Radic. Res.. 2017 Oct 19
• OS 02-05 MYD88 ON MACROPHAGE TRIGGERS CATHEPSIN L ACTIVATION DRIVEN VASCULAR INTIMAL HYPERPLASIA.
  Cai J, Yuan H, Yang H, Billiar TR, Chen AF> ;J. Hypertens.. 2016-09-01
• Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Recepto...
  Zhang L, Xiang W, Wang G, Yan Z, Zhu Z, Guo Z, Sengupta R, Chen AF, Loughran PA, Lu B, Wang Q, Billiar TR> ;J. Biol. Chem.. 2016-07-15
• Regulator of G-Protein Signaling 10 Negatively Regulates Cardiac Remodeling by Blocking Mitogen-Activated Protein Kinase-Extracellular Signal-Regulated Protein Kinase ...
  Miao R, Lu Y, Xing X, Li Y, Huang Z, Zhong H, Huang Y, Chen AF, Tang X, Li H, Cai J, Yuan H> ;Hypertension. 2016-01-01
• HMGB1-Driven Inflammation and Intimal Hyperplasia After Arterial Injury Involves Cell-Specific Actions Mediated by TLR4.
  Cai J, Yuan H, Wang Q, Yang H, Al-Abed Y, Hua Z, Wang J, Chen D, Wu J, Lu B, Pribis JP, Jiang W, Yang K, Hackam DJ, Tracey KJ, Billiar TR, Chen AF> ;Arterioscler. Thromb. Vasc. Biol.. 2015-12-01
• ADAR1 Prevents Liver Injury from Inflammation and Suppresses Interferon Production in Hepatocytes.
  Wang, G.,Wang, H.,Singh, S.,Zhou, P.,Yang, S.,Wang, Y.,Zhu, Z.,Zhang, J.,Chen, A.,Billiar, T.,Monga, S. P.,Wang, Q.> ;Am. J. Pathol.. 2015 Oct 11
• HIV protease inhibitors in pulmonary hypertension: rationale and design of a pilot trial in idiopathic pulmonary arterial hypertension.
  Li Y, Li X, Yu Z, Cai J, Billiar TR, Chen AF, Lv B, Chen Z, Huang Z, Yang G, Song J, Liu B, Yuan H> ;Pulm Circ. 2015-09-01
• Inhibition of PKR impairs angiogenesis through a VEGF pathway.
  Zhu Z, Zhong H, Zhou Q, Hu X, Chen D, Wang J, Wu J, Cai J, Zhou S, Chen AF> ;Am. J. Physiol. Endocrinol. Metab.. 2015-03-15
• Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs.
  Yang, S.,Deng, P.,Zhu, Z.,Zhu, J.,Wang, G.,Zhang, L.,Chen, A. F.,Wang, T.,Sarkar, S. N.,Billiar, T. R.,Wang, Q.> ;J. Immunol.. 2014 Aug 31
• MicroRNA miR-27b Rescues Bone Marrow-Derived Angiogenic Cell Function and Accelerates Wound Healing in Type 2 Diabetes Mellitus.
  Wang, J. M.,Tao, J.,Chen, D. D.,Cai, J. J.,Irani, K.,Wang, Q.,Yuan, H.,Chen, A. F.> ;Arterioscler. Thromb. Vasc. Biol.. 2013 Nov 02
• Oxidative Stress-Mediated Thrombospondin-2 Upregulation Impairs Bone Marrow-Derived Angiogenic Cell Function in Diabetes Mellitus.
  Bae, O. N.,Wang, J. M.,Baek, S. H.,Wang, Q.,Yuan, H.,Chen, A. F.> ;Arterioscler. Thromb. Vasc. Biol.. 2013 Aug
• Coronary flow velocity reserve is improved by PPAR-α agonist fenofibrate in patients with hypertriglyceridemia.
  Wang G, He L, Liu J, Yu J, Feng X, Li F, Hao Y, Mao J, Hong T, Chen AF, Wang X> ;Cardiovasc Ther. 2013-06-01
• Ascorbate in Aqueous Humor Augments Nitric Oxide Production by Macrophages
  Alex Chen, MD> ;The Journal of Immunology. 2013 Jan 15
• Free radical biology of the cardiovascular system.
  Chen, A. F.,Chen, D. D.,Daiber, A.,Faraci, F. M.,Li, H.,Rembold, C. M.,Laher, I.> ;Clin. Sci.. 2012 Mar 30
• Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues.
  Laing S, Wang G, Briazova T, Zhang C, Wang A, Zheng Z, Gow A, Chen AF, Rajagopalan S, Chen LC, Sun Q, Zhang K> ;Am. J. Physiol., Cell Physiol.. 2010-10-01
• Angiotensin II stimulates intercellular adhesion molecule-1 via an AT1 receptor/nuclear factor-kappaB pathway in brain microvascular endothelial cells.
  Liu H, Wei X, Sun R, Cai Y, Lou H, Wang J, Chen AF, Zhang X> ;Life Sci.. 2006-02-16
• Epstein-Barr virus LMP1 modulates the malignant potential of gastric carcinoma cells involving apoptosis.
  Sheu LF, Chen A, Wei YH, Ho KC, Cheng JY, Meng CL, Lee WH> ;Am. J. Pathol.. 1998-01-01
• Enhanced malignant progression of nasopharyngeal carcinoma cells mediated by the expression of Epstein-Barr nuclear antigen 1 in vivo.
  Sheu LF, Chen A, Meng CL, Ho KC, Lee WH, Leu FJ, Chao CF> ;J. Pathol.. 1996-11-01
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