AlexanderT.PearsonMDPhD

Head & Neck Cancer

Assistant Professor of Medicine; Director, University of Chicago Head/Neck Cancer Program Director, Data Sciences in Hematoloy/Oncology

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Overview of Dr. Pearson

Dr. Alexander Pearson is an oncologist in Chicago, IL and is affiliated with University of Chicago Medical Center. He received his medical degree from University of Rochester School of Medicine and Dentistry and has been in practice 7 years. He specializes in head & neck cancer and is experienced in neoplasms of the salivary glands and head and neck oncology.

Office
5758 S. Maryland Ave.
Chicago, IL 60637
Book by Phone+1(740) 200-4711
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Education & Training

University of Michigan Health SystemFellowship, Hematology and Medical Oncology, 2012 - 2017
University of Michigan Health SystemResidency, Internal Medicine, 2010 - 2013
University of Rochester School of Medicine and DentistryClass of 2010

Certifications & Licensure

IL State Medical License 2017 - 2026
MI State Medical License 2010 - 2020
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Leif B. Sorenson Award The University of Chicago Department of Medicine, 2022
NextGen Innovator HemOnc Today, 2019
40 under 40 Chicago Scientists HaloCures, 2019

Clinical Trials

Observational Prospective Study OPTIMA II - Follow-up Start of enrollment: 2014 May 01
Completed
Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer Start of enrollment: 2017 Jun 27
Active, not recruiting
Phase 2

Publications & Presentations

PubMed

Validation of the RSClin risk calculator in the National Cancer Data Base.
Augustin G L Vannier, Asim Dhungana, Fangyuan Zhao, Nan Chen, Sarah Shubeck, Olwen M Hahn, Rita Nanda, Nora T Jaskowiak, Gini F Fleming, Olufunmilayo I Olopade, Alexan...> ;Cancer. 2024 Apr 15
5 citations
Slideflow: deep learning for digital histopathology with real-time whole-slide visualization.
Sara Kochanny, Emma Dyer, Siddhi Ramesh, Matteo Sacco, Prajval Mohan, James M Dolezal, Andrew Srisuwananukorn, Frederick M Howard, Anran Li, Alexander T Pearson> ;BMC Bioinformatics. 2024 Mar 27
Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinoma.
Jagadeeshan, S., Suryamohan, K., Shin, N., Mathukkada, S., Boyko, A., Melikhova, D., Tsareva, A., Yunusova, L., Pravdivtseva, E., Stupichev, D., Shaposhnikov, K., Pete...> ;Oral Oncology. 2024 Feb 1
Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model.
Daniel R Bergman, Yixuan Wang, Erica Trujillo, Anthony A Fernald, Lie Li, Trachette L Jackson, Alexander T Pearson, Randy F Sweis> ;Frontiers in Immunology. 2024 Jan 1
1 citations
Mathematical model predicts tumor control patterns induced by fast and slow cytotoxic T lymphocyte killing mechanisms.
Wang, Y., Bergman, D., Trujillo, E., Jackson, T., Pearson, A., Sweis, R.> ;Scientific Reports. 2023 Dec 18
1 citations
The use of deep learning state-of-the-art architectures for oral epithelial dysplasia grading: A comparative appraisal.
Anna Luíza Damaceno Araújo, Viviane Mariano da Silva, Matheus Cardoso Moraes, Henrique Alves de Amorim, Felipe Paiva Fonseca, Maria Sissa Pereira Sant'Ana, Ricardo Alv...> ;Journal of Oral Pathology & Medicine. 2023 Nov 1
Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study.
Gregory Patrick Veldhuizen, Christoph Röcken, Hans-Michael Behrens, Didem Cifci, Hannah Sophie Muti, Takaki Yoshikawa, Tomio Arai, Takashi Oshima, Patrick Tan, Matthia...> ;Gastric Cancer. 2023 Sep 1
5 citations
Deep learning generates synthetic cancer histology for explainability and education.
James M Dolezal, Rachelle Wolk, Hanna M Hieromnimon, Frederick M Howard, Andrew Srisuwananukorn, Dmitry Karpeyev, Siddhi Ramesh, Sara Kochanny, Jung Woo Kwon, Meghana ...> ;NPJ Precision Oncology. 2023 May 29
6 citations
Artificial Intelligence in Clinical Oncology: From Data to Digital Pathology and Treatment.
Kirthika Senthil Kumar, Vanja Miskovic, Agata Blasiak, Raghav Sundar, Alessandra Laura Giulia Pedrocchi, Alexander T Pearson, Arsela Prelaj, Dean Ho> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2023 May 1
72 citations
Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers.
Catherine A Gao, Frederick M Howard, Nikolay S Markov, Emma C Dyer, Siddhi Ramesh, Yuan Luo, Alexander T Pearson> ;NPJ Digital Medicine. 2023 Apr 26
Adapting a Medical School Cancer Research Education Program to the Virtual Environment: a Mixed-Methods Study.
Omar R Vayani, Hassaan Asif, Aviva Klein, Olwen M Hahn, Alexander T Pearson, Vineet M Arora, Olufunmilayo I Olopade, Daniel W Golden> ;Journal of Cancer Education. 2023 Oct 1
6 citations
Machine learning for the prediction of toxicities from head and neck cancer treatment: A systematic review with meta-analysis.
Anna Luíza Damaceno Araújo, Matheus Cardoso Moraes, Maria Eduarda Pérez-de-Oliveira, Viviane Mariano da Silva, Cristina Saldivia-Siracusa, Caique Mariano Pedroso, Marc...> ;Oral Oncology. 2023 May 1
Clinicians' perception of oral potentially malignant disorders: a pitfall for image annotation in supervised learning.
Anna Luíza Damaceno Araújo, Eduardo Santos Carlos de Souza, Isabel Schausltz Pereira Faustino, Cristina Saldivia-Siracusa, Tamires Brito-Sarracino, Márcio Ajudarte Lop...> ;Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2023 Sep 1
2 citations
Applications of Deep Learning in Endocrine Neoplasms.
Siddhi Ramesh, James M Dolezal, Alexander T Pearson> ;Surgical Pathology Clinics. 2023 Mar 1
1 citations
The EU-funded ILUNG Project: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy.
Arsela Prelaj, Monica Ganzinelli, Francesco Trovo', Laila C Roisman, Alessandra Laura Giulia Pedrocchi, Sokol Kosta, Marcello Restelli, Emilia Ambrosini, Massimo Brogg...> ;Clinical Lung Cancer. 2023 Jun 1
5 citations
Machine learning for detection and classification of oral potentially malignant disorders: A conceptual review.
Lucas Lacerda de Souza, Felipe Paiva Fonseca, Anna Luiza Damaceno Araújo, Marcio Ajudarte Lopes, Pablo Agustin Vargas, Syed Ali Khurram, Luiz Paulo Kowalski, Harim Tav...> ;Journal of Oral Pathology & Medicine. 2023 Mar 1
Deep learning applications in visual data for benign and malignant hematologic conditions: a systematic review and visual glossary.
Andrew Srisuwananukorn, Mohamed E Salama, Alexander T Pearson> ;Haematologica. 2023 Aug 1
6 citations
Machine learning concepts applied to oral pathology and oral medicine: A convolutional neural networks' approach.
Anna Luíza Damaceno Araújo, Viviane Mariano da Silva, Maíra Suzuka Kudo, Eduardo Santos Carlos de Souza, Cristina Saldivia-Siracusa, Daniela Giraldo-Roldán, Marcio Aju...> ;Journal of Oral Pathology & Medicine. 2023 Feb 1
4 citations
Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images.
Alexander Partin, Thomas Brettin, Yitan Zhu, James M Dolezal, Sara Kochanny, Alexander T Pearson, Maulik Shukla, Yvonne A Evrard, James H Doroshow, Rick L Stevens> ;Frontiers in Medicine. 2023 Jan 1
1 citations
Author Correction: A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer.
Manijeh Goldberg, Aaron Manzi, Amritpreet Birdi, Brandon Laporte, Peter Conway, Stefanie Cantin, Vasudha Mishra, Alka Singh, Alexander T Pearson, Eric R Goldberg, Sam ...> ;Nature Communications. 2022 Dec 21
7 citations
Multimodal deep learning: An improvement in prognostication or a reflection of batch effect?
Frederick M Howard, Jakob Nikolas Kather, Alexander T Pearson> ;Cancer Cell. 2023 Jan 9
19 citations
Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology.
James M Dolezal, Andrew Srisuwananukorn, Dmitry Karpeyev, Siddhi Ramesh, Sara Kochanny, Brittany Cody, Aaron S Mansfield, Sagar Rakshit, Radhika Bansal, Melanie C Bois...> ;Nature Communications. 2022 Nov 2
3 citations
Highly accurate response prediction in high-risk early breast cancer patients using a biophysical simulation platform.
Frederick M Howard, Gong He, Joseph R Peterson, J R Pfeiffer, Tyler Earnest, Alexander T Pearson, Hiroyuki Abe, John A Cole, Rita Nanda> ;Breast Cancer Research and Treatment. 2022 Nov 1
16 citations
A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer.
Manijeh Goldberg, Aaron Manzi, Amritpreet Birdi, Brandon Laporte, Peter Conway, Stefanie Cantin, Vasudha Mishra, Alka Singh, Alexander T Pearson, Eric R Goldberg, Sam ...> ;Nature Communications. 2022 Aug 17
14 citations
A 2D Nanoradiosensitizer Enhances Radiotherapy and Delivers STING Agonists to Potentiate Cancer Immunotherapy.
Taokun Luo, Geoffrey T Nash, Xiaomin Jiang, Xuanyu Feng, Jianming Mao, Jianqiao Liu, Aditya Juloori, Alexander T Pearson, Wenbin Lin> ;Advanced Materials. 2022 Sep 1
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Press Mentions

ChatGPT Writes Convincing Fake Scientific Abstracts That Fool Reviewers in StudyJanuary 10th, 2023
First He Survived Cancer – Now He Studies ItNovember 14th, 2022
ASCO Annual Meeting Returns to Chicago, Celebrates New Progress in CancerJune 15th, 2022
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