AmandaMTermuhlenMD

Pediatric Hematology & Oncology • Minneapolis, MN

Pediatric Hematologic Oncology

Associate Dean for Faculty Affairs, Professor of Pediatrics, University of Minnesota Medical School

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Office
University of Minnesota Medical School
Mayo Building, 420 Delaware
Minneapolis, MN 55455
Phone+1 612-624-5442
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Education & Training

Cincinnati Children's Hospital Medical CenterFellowship, Pediatric Hematology/Oncology, 1987 - 1990
Wright State UniversityResidency, Pediatrics, 1984 - 1987
Ohio State University College of MedicineClass of 1984

Certifications & Licensure

OH State Medical License 1987 - 2026
MN State Medical License 2018 - 2025
CA State Medical License 2011 - 2019
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302) Start of enrollment: 2005 Sep 01
Completed
Phase 2
Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301) Start of enrollment: 2006 Jan 01
Completed
Phase 1, Phase 2
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Start of enrollment: 2007 May 01
Completed
Phase 3
Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Start of enrollment: 2007 Mar 01
Completed
Phase 3
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET Start of enrollment: 2007 Mar 26
Active, not recruiting
Phase 3
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Start of enrollment: 2007 Jan 22
Active, not recruiting
Phase 3
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) Start of enrollment: 2006 Dec 01
Completed
Phase 3
Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2008 Jan 15
Active, not recruiting
Phase 3
Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System Start of enrollment: 2008 Dec 08
Active, not recruiting
Phase 3
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Metabolic Syndrome in Bone Marrow Transplant Survivors Start of enrollment: 2009 Mar 01
Terminated
Not Applicable
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia Start of enrollment: 2009 Mar 09
Completed
Phase 3
Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma Start of enrollment: 2006 Sep 25
Completed
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Tissue From Young Patients With Cancer Start of enrollment: 2007 Mar 05
Recruiting
Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma Start of enrollment: 2008 Feb 04
Completed
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Collecting and Storing Biological Samples From Young Patients With Hodgkin?s Lymphoma Start of enrollment: 2006 Oct 23
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Study of Blood Samples From Newborns With Down Syndrome Start of enrollment: 2009 Feb 23
Completed
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma Start of enrollment: 2005 May 30
Completed
Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma Start of enrollment: 2010 Jan 01
Completed
Phase 2
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia Start of enrollment: 2011 Feb 01
Completed
Phase 2
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Start of enrollment: 2010 Nov 22
Completed
Phase 2
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma Start of enrollment: 2010 Oct 01
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Start of enrollment: 2011 May 01
Completed
Not Applicable
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Start of enrollment: 2011 Sep 01
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor Start of enrollment: 2011 Aug 01
Completed
Phase 2
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. Start of enrollment: 2013 Aug 20
Completed
Phase 2
NAC to Prevent Cisplatin-induced Hearing Loss Start of enrollment: 2016 Mar 01
Completed
Phase 1
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
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Publications & Presentations

PubMed

4 citations
Poverty and relapse risk in children with acute lymphoblastic leukemia: a Children's Oncology Group study AALL03N1 report.
Aman Wadhwa, Yanjun Chen, Lindsey Hageman, Anna Hoppmann, Anne Angiolillo, David S Dickens, Joseph P Neglia, Yaddanapudi Ravindranath, A Kim Ritchey, Amanda Termuhlen,...> ;Blood. 2023 Jul 20
3 citations
Late Health Outcomes Among Survivors of Wilms Tumor Diagnosed Over Three Decades: A Report From the Childhood Cancer Survivor Study.
Brent R Weil, Andrew J Murphy, Qi Liu, Rebecca M Howell, Susan A Smith, Christopher B Weldon, Elizabeth A Mullen, Arin L Madenci, Wendy M Leisenring, Joseph P Neglia, ...> ;Journal of Clinical Oncology. 2023 May 10
8 citations
Body mass index during maintenance therapy and relapse risk in children with acute lymphoblastic leukemia: A Children's Oncology Group report.
Aman Wadhwa, Yanjun Chen, Lindsey Hageman, Anna L Hoppmann, Anne Angiolillo, David S Dickens, Glen Lew, Joseph P Neglia, Yaddanapudi Ravindranath, A Kim Ritchey, Amand...> ;Cancer. 2023 Jan 1
1 citations
Gender Distribution of Authors of Evaluation Letters for Promotion at One Medical School.
Mary E Logeais, Margaret Eckerstorfer, Kristina M Krohn, Susan A Everson-Rose, Amanda M Termuhlen, Anne M Joseph> ;Academic Medicine. 2022 Dec 1
Survival of pediatric Hodgkin lymphoma patients treated with doxorubicin, bleomycin, vincristine, etoposide, prednisone, and cyclophosphamide (ABVE-PC) versus doxorubi...
Sebastian de Armas, Carolina Huertas-Ayala, Randall Y Chan, Yueh-Yun Chi, Winston W Huh, Amanda Termuhlen, Paul S Gaynon, Alexandra E Kovach, Andrew Doan> ;Pediatric Blood & Cancer. 2022 May 1
1 citations
Using a Community-Based Participatory Approach to Address Gender Equity in Academic Medicine: The Center for Women in Medicine and Science at the University of Minnesota.
Jerica M. Berge, Kait C. Macheledt, Sophie Watson, Heather Dorr, Snigdha Pusalavidyasagar, Alicia Kunin-Batson, Rebekah Pratt, Sara L Zimmer, Jakub Tolar, Amanda Termu...> ;Academic Medicine. 2021 Aug 31
13 citations
Solid organ transplantation after treatment for childhood cancer: a retrospective cohort analysis from the Childhood Cancer Survivor Study
Andrew C. Dietz, Kristy Seidel, Wendy M. Leisenring, Daniel A. Mulrooney, Jean M. Tersak, Richard D. Glick, Cathy A. Burnweit, Daniel M. Green, Lisa Diller, Susan A. S...> ;The Lancet. Oncology. 2019 Oct 1
18 citations
IRF4 translocation status in pediatric follicular and diffuse large B-cell lymphoma patients enrolled in Children's Oncology Group trials
Karen M. Chisholm, Jeffrey Mohlman, Michael Liew, Amanda M. Termuhlen, Mitchell S. Cairo, Thomas G. Gross, Sherrie L. Perkins, Rodney R. Miles> ;Pediatric Blood & Cancer. 2019 Aug 1
12 citations
Advances in cellular and humoral immunotherapy – implications for the treatment of poor risk childhood, adolescent, and young adult B‐cell non‐Hodgkin lymphoma
Yaya Chu, Aliza Gardenswartz, Amanda M. Termuhlen, Mitchell S. Cairo> ;British Journal of Haematology. 2019 Jun 1
5 citations
Pre-irradiation intensive induction and marrow-ablative consolidation chemotherapy in young children with newly diagnosed high-grade brainstem gliomas: report of the "...
Diana S Osorio, Neha Patel, Lingyun Ji, Richard Sposto, Joseph Stanek, Sharon Gardner, Jeffrey C. Allen, Albert Cornelius, Geoffrey McCowage, Amanda M. Termuhlen, Ira ...> ;Journal of Neuro-Oncology. 2018 Nov 3
87 citations
Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R
Lisa Giulino-Roth, Tara O'Donohue, Zhengming Chen, Nancy L. Bartlett, Ann S. LaCasce, William Martin-Doyle, Matthew J. Barth, Kimberly Davies, Kristie A. Blum, Beth A....> ;British Journal of Haematology. 2017 Dec 1
8 citations
Genomic characterization of pediatric B‐lymphoblastic lymphoma and B‐lymphoblastic leukemia using formalin‐fixed tissues
Julia Meyer, Delu Zhou, Clinton C. Mason, Jonathan M. Downie, Vladimir Rodic, Minnie Abromowitch, Birte Wistinghausen, Amanda M. Termuhlen, Anne L. Angiolillo, Sherrie...> ;Pediatric Blood & Cancer. 2017 Jul 1
5 citations
Natural killer/T-cell lymphomas in pediatric and adolescent patients.
Amanda M. Termuhlen> ;Clinical Advances in Hematology & Oncology. 2017 Mar 1
24 citations
Comparison of self-report and electronic monitoring of 6MP intake in childhood ALL: a Children’s Oncology Group study
Wendy Landier, Yanjun Chen, Lindsey Hageman, Heeyoung Kim, Bruce Bostrom, Jacqueline Casillas, David S. Dickens, William E. Evans, Kelly W. Maloney, Leo Mascarenhas, A...> ;Blood. 2017 Apr 6
19 citations
Mercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's O...
, , , , , , , , , , , , , , , , > ;Journal of Clinical Oncology. 2017 Mar 24
11 citations
Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.
Adam J. de Smith, Juhi Ojha, Stephen S. Francis, Alyson A. Endicott, Helen M. Hansen, Ivan Smirnov, Amanda M. Termuhlen, Kyle M. Walsh, Catherine Metayer, Joseph L. Wi...> ;Oncotarget. 2016 Sep 24
27 citations
A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros.
Joseph L. Wiemels, A J de Smith, Jianqiao Xiao, Seung-Tae Lee, Marcus O. Muench, Marina E. Fomin, Mi Zhou, Helen M. Hansen, Amanda M. Termuhlen, Catherine Metayer, Kyl...> ;Leukemia. 2016 May 1
37 citations
Rare Pediatric Non‐Hodgkin Lymphomas: A Report From Children's Oncology Group Study ANHL 04B1
Chibuzo O'Suoji, Jennifer J.G. Welch, Sherrie L. Perkins, Lynette M. Smith, Sheila Weitzman, Stephen J. Simko, Paul J. Galardy, Catherine M. Bollard, Thomas G. Gross, ...> ;Pediatric Blood & Cancer. 2016 May 1
196 citations
Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure
Paul G. Richardson, Marcie L. Riches, Nancy A. Kernan, Joel A. Brochstein, Shin Mineishi, Amanda M. Termuhlen, Sally Arai, Stephan A. Grupp, Eva C. Guinan, Paul L. Mar...> ;Blood. 2016 Mar 31
69 citations
The importance of assessing priorities of reproductive health concerns among adolescent and young adult patients with cancer.
Devin Murphy, James L. Klosky, Damon R. Reed, Amanda M. Termuhlen, Susan Shannon, Gwendolyn P. Quinn> ;Cancer. 2015 Aug 1
87 citations
Systemic Exposure to Thiopurines and Risk of Relapse in Children With Acute Lymphoblastic Leukemia: A Children’s Oncology Group Study
, , , , , , , , , , , , , , , , , > ;JAMA Oncology. 2015 Jun 1
11 citations
CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells
Dorothea E. Myers, Seang Yiv, Sanjive Qazi, Hong Ma, Ingrid Cely, Anoush Shahidzadeh, Martha Arellano, Erin Finestone, Paul S. Gaynon, Amanda M. Termuhlen, Jianjun Che...> ;Integrative Biology. 2014 Jul 22
13 citations
Pitfalls of Using Administrative Data Sets to Describe Clinical Outcomes in Sickle Cell Disease
Susan Claster, Amanda M. Termuhlen, Sheree M. Schrager, Julie A. Wolfson, Ellen Iverson> ;Pediatric Blood & Cancer. 2013 Aug 26
5 citations
Constitutive Function of the Ikaros Transcription Factor in Primary Leukemia Cells from Pediatric Newly Diagnosed High-Risk and Relapsed B-precursor ALL Patients
Fatih M. Uckun, Hong Ma, Rita Ishkhanian, Martha Arellano, Anoush Shahidzadeh, Amanda M. Termuhlen, Paul S. Gaynon, Sanjive Qazi> ;Plos One. 2013 Nov 20
30 citations
Why Healthcare Providers Should Focus on the Fertility of AYA Cancer Survivors: It's Not Too Late!
Devin Murphy, Etan Orgel, Amanda M. Termuhlen, Susan Shannon, Krista Warren, Gwendolyn P. Quinn> ;Frontiers in Oncology. 2013 Oct 7
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Other

Overview of pediatric non-Hodgkin lymphoma
Termuhlen AM, Gross TG
http://www.uptodate.com/contents/overview-of-pediatric-non-hodgkin-lymphoma
UpToDate, Wolters Kluwer Health - 2013-02-26

Press Mentions

Children’s Hospital Los Angeles Expands Cardiology and Hematology/Oncology Staff in South Bay Outpatient CenterAugust 11th, 2016