AmirLermanMD

Cardiology • Rochester, MN

Professor, Internal Medicine, Mayo Medical School

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Office
200 1st Street SW
Rochester, MN 55905
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Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Cardiovascular Disease, 1991 - 1994
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1987 - 1987
Maimonides Medical CenterResidency, Internal Medicine, 1986 - 1987
Technion-Israel Inst of Technology Faculty of MedicineClass of 1986

Certifications & Licensure

AZ State Medical License 2011 - 2026
MN State Medical License 1989 - 2025
American Board of Internal Medicine Internal Medicine
National Board of Physicians and Surgeons Cardiovascular Disease
National Board of Physicians and Surgeons Internal Medicine

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Clinical Trials

Correlation of Endothelial Function and Early Coronary Artery Disease in Humans Start of enrollment: 2001 Jul 01
Completed
Phase 3
Effect of Chronic Statin and Viagra Therapy in Persons With Endothelial Cell Dysfunction Start of enrollment: 2004 Jun 01
Withdrawn
Not Applicable
The Acute Effect of Statins on Inflammatory Markers of Athersclerotic Tissue Start of enrollment: 2002 Sep 01
Completed
Not Applicable
Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary Intervention Start of enrollment: 2002 Nov 01
Terminated
Not Applicable
Comparison of Coronary CT With IVUS in Heart Transplant Population Start of enrollment: 2007 Nov 01
Withdrawn
Not Applicable
Effects of Cranberry Juice on Risk Factors for Cardiovascular Disease Start of enrollment: 2008 Feb 01
Completed
Effects of EGCG-Enhanced Extra Virgin Olive Oil on Endothelial Function Start of enrollment: 2008 Feb 01
Completed
The Effect of Tekturna on Endothelial Function and Endothelial Progenitor Cells in Patients With Early Atherosclerosis Start of enrollment: 2010 Feb 01
Terminated
Phase 3
Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans Start of enrollment: 2010 Feb 04
Completed
Phase 3
Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome Start of enrollment: 2011 Sep 01
Completed
Not Applicable
Assessment of Cardiac Allograft Vasculopathy With Optical Coherence Tomography Start of enrollment: 2011 Aug 01
Completed
Lp-PLA2 and Coronary Atherosclerosis in Humans Start of enrollment: 2009 Feb 01
Completed
Not Applicable
Assessment of Coronary Plaque Composition Start of enrollment: 2010 Jan 01
Completed
Phase 1
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit Start of enrollment: 2012 Oct 01
Active, not recruiting
Olive Oil and Cardiovascular Health Start of enrollment: 2013 Aug 01
Withdrawn
Not Applicable
Is Our Microbiome a Predictor of Cardiac Risk Start of enrollment: 2013 Nov 01
Recruiting
Effects of Chardonnay Seed Flour on Vascular Health Start of enrollment: 2014 Mar 01
Completed
Not Applicable
Study of Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis Start of enrollment: 2018 Jun 15
Completed
Phase 1
Feasibility and Efficacy of Coronary Sinus Narrowing in Patients With Coronary Microvascular Dysfunction Start of enrollment: 2021 Jun 28
Completed
Not Applicable
A Study of Sleep Patterns to Determine Predictive Markers Due to Cardiovascular Disease in Elderly Patients Start of enrollment: 2023 May 23
Enrolling by invitation
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Physiological Assessment with iFR prior to FFR Measurement in Left Main Disease.
Takayuki Warisawa, Christopher M Cook, Yousif Ahmad, James P Howard, Henry Seligman, Christopher Rajkumar, Takumi Toya, Shunichi Doi, Akihiro Nakajima, Masafumi Nakaya...> ;Cardiovascular Intervention and Therapeutics. 2024 Apr 20
Patients With Coronary Microvascular Dysfunction Have Less Circulating α-Klotho.
Ilke Ozcan, Tamara Tchkonia, James L Kirkland, Bradley Lewis, Lilach O Lerman, Nadia Akhiyat, Rajiv Gulati, Abhiram Prasad, Amir Lerman> ;Journal of the American Heart Association. 2024 Apr 19
Effect of mechanical fatigue on commercial bioprosthetic TAVR valve mechanical and microstructural properties.
Christopher Noble, Alexander Hooke, David Morse, Dan Dragomir-Daescu, Jeffery Salisbury, Melissa D Young, Amir Lerman, Arush Rajotia> ;Journal of the Mechanical Behavior of Biomedical Materials. 2024 Jun 1
Predictive Value of Artificial Intelligence-Enabled Electrocardiography in Patients With Takotsubo Cardiomyopathy.
Yoshihisa Kanaji, Ilke Ozcan, David N Tryon, Ali Ahmad, Jaskanwal Deep Singh Sara, Brad Lewis, Paul Friedman, Peter A Noseworthy, Lilach O Lerman, Tsunekazu Kakuta, Za...> ;Journal of the American Heart Association. 2024 Mar 5
1 citations
Coronary Vasomotor Dysfunction Is Associated With Cardiovascular Events in Patients With Nonobstructive Coronary Artery Disease.
Yoshihisa Kanaji, Ali Ahmad, Ilke Ozcan, Nadia Akhiyat, Abhiram Prasad, Claire E Raphael, Tsunekazu Kakuta, Lilach O Lerman, Amir Lerman, Jaskanwal Deep Singh Sara> ;JACC. Cardiovascular Interventions. 2024 Feb 26
Coronary Artery Calcification: Current Concepts and Clinical Implications.
Carlotta Onnis, Renu Virmani, Kenji Kawai, Valentina Nardi, Amir Lerman, Filippo Cademartiri, Roberta Scicolone, Alberto Boi, Terenzio Congiu, Gavino Faa, Peter Libby,...> ;Circulation. 2024 Jan 16
1 citations
Changes in vascular function and correlation with cardiotoxicity in women with newly diagnosed breast cancer undergoing HER2-directed therapy with and without anthracy...
Nhola, L., Kailash, V., Zhang, S., Lewis, B., Hazim, A., Sandhu, N., Lerman, A., Loprinzi, C., Ruddy, K., Villarraga, H., Herrmann, J.> ;European Heart Journal Open. 2024 Jan 1
Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Makoto Araki, Seung-Jung Park, Harold L Dauerman, Shiro Uemura, Jung-Sun Kim, Carlo Di Mario, Thomas W Johnson, Giulio Guagliumi, Adnan Kastrati, Michael Joner, Niels ...> ;Nature Reviews. Cardiology. 2024 May 1
Altered immune cell phenotypes within chronically ischemic human kidneys distal to occlusive renal artery disease.
Xiang-Yang Zhu, Nattawat Klomjit, Aditya S Pawar, Amrutesh S Puranik, Zhi-Zhang Yang, Esther Lutgens, Alfonso Eirin, Amir Lerman, Stephen C Textor, Lilach O Lerman> ;American Journal of Physiology. Renal Physiology. 2024 Feb 1
Machine learning detects symptomatic patients with carotid plaques based on 6-type calcium configuration classification on CT angiography.
Francesco Pisu, Hui Chen, Bin Jiang, Marco Virgilio Usai, Martin Austermann, Yousef Shehada, Elias Johansson, Jasjit Suri, Giuseppe Lanzino, John Benson, Valentina Nar...> ;European Radiology. 2023 Nov 20
Digital Tool-Assisted Hospitalization Detection in the Tailored Antiplatelet Initiation to Lessen Outcomes due to Decreased Clopidogrel Response After Percutaneous Cor...
Robert Avram, Julia Byrne, Derek So, Erin Iturriaga, Ryan Lennon, Vishakantha Murthy, Nancy Geller, Shaun Goodman, Charanjit Rihal, Yves Rosenberg, Kent Bailey, Michae...> ;Journal of Medical Internet Research. 2023 Nov 10
1 citations
Microvascular cardiac amyloidosis-Cardiac involvement of amyloidosis presenting as typical chest pain.
Iuliana Vaxman, Caroline Kaufman, Amir Lerman, Morie A Gertz> ;American Journal of Hematology. 2023 Dec 1
What Can Biologic Aging Tell Us About the Effects of Mental Stress on Vascular Health.
Jaskanwal Deep Singh Sara, Lilach O Lerman, Amir Lerman> ;Hypertension. 2023 Dec 1
4 citations
Comprehensive Management of ANOCA, Part 2-Program Development, Treatment, and Research Initiatives: JACC State-of-the-Art Review.
Smilowitz, N., Prasad, M., Widmer, R., Toleva, O., Quesada, O., Sutton, N., Lerman, A., Reynolds, H., Kesarwani, M., Savage, M., Sweeny, J., Janaszek, K., Barseghian E...> ;Journal of the American College of Cardiology. 2023 Sep 19
8 citations
Comprehensive Management of ANOCA, Part 1-Definition, Patient Population, and Diagnosis: JACC State-of-the-Art Review.
Bruce A Samuels, Samit M Shah, R Jay Widmer, Yuhei Kobayashi, Steven E S Miner, Viviany R Taqueti, Allen Jeremias, Ahmed Albadri, John A Blair, Kathleen E Kearney, Jan...> ;Journal of the American College of Cardiology. 2023 Sep 19
1 citations
Guess What We Can Hear-Novel Voice Biomarkers for the Remote Detection of Disease.
Jaskanwal Deep Singh Sara, Diana Orbelo, Elad Maor, Lilach O Lerman, Amir Lerman> ;Mayo Clinic Proceedings. 2023 Sep 1
Augmented Reality and Ultrasound-Guided Vascular Access.
Abdullah Al-Abcha, Mohamad Alkhouli, Abhiram Prasad, Malcolm Bell, Suraj Yalamuri, Amir Lerman, Rajiv Gulati, Trevor Simard> ;Circulation. Cardiovascular Interventions. 2023 Sep 1
1 citations
Prognostic value of peripheral endothelial function on major adverse cardiovascular events above traditional risk factors.
Nazanin Rajai, Takumi Toya, Jaskanwal D Sara, Francisco Lopez-Jimenez, Lilach O Lerman, Amir Lerman, Arush Rajotia> ;European Journal of Preventive Cardiology. 2023 Nov 9
2 citations
Coronary Reactivity Assessment Is Associated With Lower Health Care-Associated Costs in Patients Presenting With Angina and Nonobstructive Coronary Artery Disease.
Ali Ahmad, Michel T Corban, James P Moriarty, Yoshihisa Kanaji, Jordan K Rosedahl, Rajiv Gulati, Charanjit S Rihal, Abhiram Prasad, Jaskanwal D Sara, Takumi Toya, Iris...> ;Circulation. Cardiovascular Interventions. 2023 Jul 1
2 citations
Obesity blunts amelioration of cardiac hypertrophy and fibrosis by human mesenchymal stem/stromal cell-derived extracellular vesicles.
Siting Hong, Weijun Huang, Xiangyang Zhu, Hui Tang, James D Krier, Li Xing, Bo Lu, Deep Gandhi, Kyra L Jordan, Ishran M Saadiq, Amir Lerman, Alfonso Eirin, Lilach O Le...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2023 Jul 1
1 citations
Deferred Versus Performed Revascularization for Left Main Coronary Disease With Hemodynamic Significance.
Takayuki Warisawa, Christopher M Cook, Yousif Ahmad, James P Howard, Henry Seligman, Christopher Rajkumar, Takumi Toya, Shunichi Doi, Akihiro Nakajima, Masafumi Nakaya...> ;Circulation. Cardiovascular Interventions. 2023 Jun 1
Patients with Carotid Intraplaque Hemorrhage Have Higher Incidence of Cerebral Microbleeds.
Valentina Nardi, John C Benson, Luca Saba, Melanie C Bois, Fredric B Meyer, Giuseppe Lanzino, Lilach O Lerman, Amir Lerman> ;Current Problems in Cardiology. 2023 Sep 1
17 citations
Senescent Cells: A Therapeutic Target in Cardiovascular Diseases.
Masayoshi Suda, Karl H Paul, Tohru Minamino, Jordan D Miller, Amir Lerman, Georgina M Ellison-Hughes, Tamar Tchkonia, James L Kirkland> ;Cells. 2023 May 2
Metabolic Syndrome Induces Epigenetic Alterations in Mitochondria-Related Genes in Swine Mesenchymal Stem Cells.
Kamalnath S Rajagopalan, Sara Kazeminia, Logan M Glasstetter, Rahele A Farahani, Xiang-Yang Zhu, Hui Tang, Kyra L Jordan, Alejandro R Chade, Amir Lerman, Lilach O Lerm...> ;Cells. 2023 Apr 27
1 citations
Physiology-guided PCI versus CABG for left main coronary artery disease: insights from the DEFINE-LM registry.
Takayuki Warisawa, Christopher M Cook, Yoshiaki Kawase, James P Howard, Yousif Ahmad, Henry Seligman, Christopher Rajkumar, Takumi Toya, Shunichi Doi, Akihiro Nakajima...> ;Cardiovascular Intervention and Therapeutics. 2023 Jul 1
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Journal Articles

Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary Intervention
Naveen L Pereira, Verghese Mathew, Charles Cagin, Amir Lerman, Charanjit Rihal, JAMA
Focus on Coronary Physiology Assessment in Special Cohorts Editorial Comment Coronary Microvasculature: Are the Small and the Mighty Cross-Talking with the Epicardial ...
Amir Lerman, Michel T Corban, Lilach O Lerman, ScienceDirect

Lectures

Dissecting the Data: Update on Spontaneous Coronary Artery Dissection
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Audience ARS Question
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Acute Coronary Syndromes in Patients with Active Hematologic Malignancies – Incidence, Management, and Outcomes
Scientific Sessions 2007, Orlando, Florida, USA
Local Low Shear Stress and Endothelial Dysfunction in Patients with Nonobstructive Coronary Atherosclerosis
American Heart Association, Scientific Sessions 2007, Orlando, Florida, USA
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Authored Content

Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary InterventionAugust 2020
Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary InterventionAugust 2020
Acute Coronary Syndromes in Patients with Active Hematologic Malignancies – Incidence, Management, and OutcomesOctober 2018
Long-Term Sirolimus for Primary Immunosuppression in Heart Transplant RecipientsFebruary 2018
Long-Term Sirolimus for Primary Immunosuppression in Heart Transplant RecipientsFebruary 2018
Long-Term Sirolimus for Primary Immunosuppression in Heart Transplant RecipientsFebruary 2018
Long-Term Sirolimus for Primary Immunosuppression in Heart Transplant RecipientsFebruary 2018
Chronic Inhibition of Lipoprotein-Associated Phospholipase A2 Does Not Improve Coronary Endothelial Function: A Prospective, Randomized-Controlled Trial☆January 2018
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Press Mentions

WizeCare Announces Know-How and Research Agreement with Mayo ClinicSeptember 7th, 2022
‘Voice Biomarker’ May Predict Chest Pain, ACS, Coronary Artery DiseaseApril 3rd, 2022
Mayo Clinic Research in the News — 11/23/2020November 23rd, 2020
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