AmirASadighi AkhaMD

Pathology • Rochester, MN

Assistant Professor, Laboratory Medicine & Pathology, Mayo Med Sch

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Office
200 1st St Sw
Rochester, MN 55905
Phone+1 507-284-2511
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Summary

Dr. Amir Sadighi Akha, MD is a pathologist in Rochester, Minnesota. He is currently licensed to practice medicine in Minnesota. He is affiliated with Mayo Clinic Hospital - Rochester and Mayo Clinic Health System-Albert Lea and Austin.

Certifications & Licensure

MN State Medical License Current

Publications & Presentations

PubMed

1 citations
Anti-cytokine autoantibodies and inborn errors of immunity.
Amir A Sadighi Akha, Attila Kumánovics> ;Journal of Immunological Methods. 2022 Sep 1
2 citations
Flow cytometry for B-cell subset analysis in immunodeficiencies.
Attila Kumánovics, Amir A Sadighi Akha> ;Journal of Immunological Methods. 2022 Oct 1
20 citations
Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study.
Seul Kee Byeon, Anil K Madugundu, Kishore Garapati, Madan Gopal Ramarajan, Mayank Saraswat, Praveen Kumar-M, Travis Hughes, Rameen Shah, Mrinal M Patnaik, Nicholas Chi...> ;The Lancet. Digital Health. 2022 Sep 1
7 citations
A Toolkit and Framework for Optimal Laboratory Evaluation of Individuals with Suspected Primary Immunodeficiency.
Vijaya Knight, Jennifer Heimall, Hey Chong, Sarada L. Nandiwada, Karin Chen, Monica G. Lawrence, Amir A. Sadighi Akha, Attila Kumánovics, Soma Jyonouchi, Suzanne Y. Ng...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2021 Sep 1
Highlights of the 33rd annual scientific meeting of the Association of Medical Laboratory Immunologists (AMLI).
Vijaya Knight, Medhat Askar, Evangelos Ntrivalas, Sarada L. Nandiwada, Lisa K. Peterson, Anne E. Tebo, Kamran Kadkhoda, John L. Schmitz, Stanley J. Naides, Melissa R. ...> ;Journal of Immunological Methods. 2021 May 1
6 citations
Asymptomatic Infant With Atypical SCID and Novel Hypomorphic RAG Variant Identified by Newborn Screening: A Diagnostic and Treatment Dilemma
Maria Chitty-Lopez, Emma Westermann-Clark, Irina Dawson, Boglarka Ujhazi, Krisztian Csomos, Kerry Dobbs, Khuong Le, Yasuhiro Yamazaki, Amir A. Sadighi Akha, Deepak Che...> ;Frontiers in Immunology. 2020 Sep 29
2 citations
A rare case of selective Igκ chain deficiency: Biologic and clinical implications.
Amir A. Sadighi Akha, Renee C. Tschumper, John Mills, Crescent R. Isham, Elizabeth E. Witty, David S. Viswanatha, Surendra Dasari, Melissa R. Snyder, David L. Murray, ...> ;The Journal of Allergy and Clinical Immunology. 2020 Apr 8
2 citations
Disseminated Pneumocystis jirovecii Infection with Osteomyelitis in a Patient with CTLA-4 Haploinsufficiency.
Aminaa Siddiqi, Anne Y. Liu, Gregory W. Charville, Christian A. Kunder, Gulbu Uzel, Amir A. Sadighi Akha, Jean Oak, Beth A. Martin, Joshua Sacha, David B. Lewis, Yael ...> ;Journal of Clinical Immunology. 2020 Jan 18
198 citations
Aging and the immune system: An overview.
Amir A. Sadighi Akha> ;Journal of Immunological Methods. 2018 Aug 14
21 citations
Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice
Amir A. Sadighi Akha, Andrew J. McDermott, Casey M. Theriot, Paul E. Carlson, Charles R. Frank, Roderick A. McDonald, Nicole R. Falkowski, Ingrid L. Bergin, Vincent B....> ;Immunology. 2015 Apr 1
29 citations
Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response
Amir A. Sadighi Akha, Casey M. Theriot, John R. Erb-Downward, Andrew J. McDermott, Nicole R. Falkowski, Heather M. Tyra, D. Thomas Rutkowski, Vincent B. Young, Gary B....> ;Immunology. 2013 Sep 1
3 citations
Use of Direct Gradient Analysis to Uncover Biological Hypotheses in 16S Survey Data and Beyond
John R. Erb-Downward, Amir A. Sadighi Akha, Juan Wang, Ning Shen, Bei He, Fernando J. Martinez, Margaret R. Gyetko, Jeffrey L. Curtis, Gary B. Huffnagle> ;Scientific Reports. 2012 Oct 26
64 citations
Interleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia.
Benjamin J. Murdock, Nicole R. Falkowski, Andrew B. Shreiner, Amir A. Sadighi Akha, Roderick A. McDonald, Eric S. White, Galen B. Toews, Gary B. Huffnagle> ;Infection and Immunity. 2012 Apr 1
30 citations
Repeated Exposure to Aspergillus fumigatus Conidia Results in CD4+ T Cell-Dependent and -Independent Pulmonary Arterial Remodeling in a Mixed Th1/Th2/Th17 Microenviron...
Andrew B. Shreiner, Benjamin J. Murdock, Amir A. Sadighi Akha, Nicole R. Falkowski, Paul J. Christensen, Eric S. White, Cory M. Hogaboam, Gary B. Huffnagle> ;Infection and Immunity. 2012 Jan 1
26 citations
Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevity.
Amir A. Sadighi Akha, James M. Harper, Adam B. Salmon, Bethany A. Schroeder, Heather M. Tyra, D. Thomas Rutkowski, Richard A. Miller> ;The Journal of Biological Chemistry. 2011 Sep 2
206 citations
Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age
Liou Y. Sun, Amir A. Sadighi Akha, Richard A. Miller, James M. Harper> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2009 Jul 1
87 citations
Fibroblasts From Naked Mole-Rats Are Resistant to Multiple Forms of Cell Injury, But Sensitive to Peroxide, Ultraviolet Light, and Endoplasmic Reticulum Stress
Adam B. Salmon, Amir A. Sadighi Akha, Rochelle Buffenstein, Richard A. Miller> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2008 Mar 1
21 citations
Age-Related Defects in Moesin/Ezrin Cytoskeletal Signals in Mouse CD4 T Cells
Gonzalo G. Garcia, Amir A. Sadighi Akha, Richard A. Miller> ;Journal of Immunology. 2007 Nov 15
642 citations
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.
D. Thomas Rutkowski, Stacey M. Arnold, Corey N. Miller, Jun-Dong Wu, Jack Shiansong Li, Kathryn M Gunnison, Kazutoshi Mori, Amir A. Sadighi Akha, David Raden, Randal J...> ;Plos Biology. 2006 Nov 7
10 citations
CD43‐independent augmentation of mouse T‐cell function by glycoprotein cleaving enzymes
Scott B. Berger, Amir A. Sadighi Akha, Richard A. Miller, Gonzalo G. Garcia> ;Immunology. 2006 Oct 1
18 citations
Enhancement of CD8 T-cell function through modifying surface glycoproteins in young and old mice.
Amir A. Sadighi Akha, Scott B. Berger, Richard A. Miller> ;Immunology. 2006 Oct 1
56 citations
Signal transduction in the aging immune system.
Amir A. Sadighi Akha, Richard A. Miller> ;Current Opinion in Immunology. 2005 Oct 1
10 citations
A glycoprotein endopeptidase enhances calcium influx and cytokine production by CD4+ T cells of old and young mice
Scott B. Berger, Amir A. Sadighi Akha, Richard A. Miller> ;International Immunology. 2005 Aug 1
31 citations
T cells in aging mice: genetic, developmental, and biochemical analyses.
Richard A. Miller, Scott B. Berger, David T. Burke, Andrzej T. Galecki, Gonzalo G. Garcia, James M. Harper, Amir A. Sadighi Akha> ;Immunological Reviews. 2005 Jun 1
40 citations
Age-associated changes in glycosylation of CD43 and CD45 on mouse CD4 T cells.
Gonzalo G. Garcia, Scott B. Berger, Amir A. Sadighi Akha, Richard A. Miller> ;European Journal of Immunology. 2005 Feb 1
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Hospital Affiliations

Mayo Clinic Hospital - RochesterRochester, Minnesota
Mayo Clinic Health System-Albert Lea and AustinAustin, Minnesota