AmitMahipalMD

Oncology • Rochester, MN

Gastrointestinal Cancer

Director, GI oncology; Professor

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Office
200 1st St SW
Rochester, MN 55905
Phone+1 507-284-2511

Fax+1 216-844-5234
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Education & Training

Sidney Kimmel Medical College at Thomas Jefferson University/TJUHFellowship, Hematology and Medical Oncology, 2008 - 2011
University of ConnecticutResidency, Internal Medicine, 2005 - 2008
Maulana Azad Medical CollegeClass of 2003, MBBS

Certifications & Licensure

OH State Medical License 2022 - 2026
FL State Medical License 2011 - 2023
MN State Medical License 2016 - 2022
PA State Medical License 2008 - 2012
American Board of Internal Medicine Medical Oncology

Clinical Trials

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 1
Vitamin E δ-Tocotrienol Multiple Dose in Healthy Subjects Start of enrollment: 2011 Oct 01
Completed
Phase 1
Oral Bicarbonate as Adjuvant for Pain Reduction in Patients With Tumor Related Pain Start of enrollment: 2013 Sep 01
Terminated
Phase 1
Phase 1b Trial of BGJ398/BYL719 in Solid Tumors Start of enrollment: 2013 Oct 01
Completed
Phase 1
A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 1
Single Agent Regorafenib in Refractory Advanced Biliary Cancers Start of enrollment: 2014 Jun 05
Completed
Phase 2
Enzalutamide in Combination With Gemcitabine and Nab-Paclitaxel for the Treatment of Advanced Pancreatic Cancer Start of enrollment: 2014 May 22
Completed
Phase 1
BYL719 in Combination With Gemcitabine and (Nab)-Paclitaxel in Locally Advanced and Metastatic Pancreatic Cancer Start of enrollment: 2014 Oct 30
Completed
Phase 1
Gemcitabine, Nab-paclitaxel and KPT-330 in Advanced Pancreatic Cancer Start of enrollment: 2014 Oct 31
Completed
Phase 1, Phase 2
Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases Start of enrollment: 2014 Oct 09
Terminated
Phase 1
TAS-102 in Treating Advanced Biliary Tract Cancers Start of enrollment: 2017 Oct 20
Completed
Phase 2
Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer Start of enrollment: 2019 Oct 18
Completed
Phase 2
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Publications & Presentations

PubMed

A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results.
Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson, Brian S Henick, Chih-Yi Liao, Amit Mahipal, Ardaman Shergill, Alexander I Spira, Jonathan...> ;Nature Medicine. 2024 Mar 27
Outcomes of Hepatic Artery-Based Therapies and Systemic Multiagent Chemotherapy in Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-analysis.
Henry Stitzel, Victoria Wu, Kavin Sugumar, David Bajor, Sakti Chakrabarti, Madison Conces, Lauren Henke, Melissa Lumish, Amit Mahipal, Amr Mohamed, Jordan M Winter, Je...> ;Annals of Surgical Oncology. 2024 Mar 19
Metabolism, toxicity and management of fruquintinib: a novel drug for metastatic colorectal cancer.
Veronica Lee Mears, Kanchi Patell, Michael H Storandt, Amit Mahipal> ;Expert Opinion on Drug Metabolism & Toxicology. 2024 Mar 20
Modified FOLFOX6 plus bevacizumab with and without nivolumab for first-line treatment of metastatic colorectal cancer: phase 2 results from the CheckMate 9X8 randomize...
Heinz-Josef Lenz, Aparna Parikh, David R Spigel, Allen L Cohn, Takayuki Yoshino, Mark Kochenderfer, Elena Elez, Spencer H Shao, Dustin Deming, Regan Holdridge, Timothy...> ;Journal for Immunotherapy of Cancer. 2024 Mar 13
Projected Incidence of Hepatobiliary Cancers and Trends Based on Age, Race, and Gender in the United States.
Wieczorek, M., Hodge, D., Elrod, J., Rosenberg, P., Storandt, M., Tella, S., Jin, Z., Mahipal, A.> ;Cancers. 2024 Feb 6
Adoption of Total Neoadjuvant Therapy in the Treatment of Locally Advanced Rectal Cancer.
Conces, M., Mahipal, A.> ;Current Oncology. 2024 Jan 10
Tumor-Informed Circulating Tumor DNA for Minimal Residual Disease Detection in the Management of Colorectal Cancer.
Zemla, T., Mitchell, J., Mathis, K., McWilliams, R., Hubbard, J., Sinicrope, F., Shi, Q., Emiloju, O., Storandt, M., Tran, N., Jethwa, K., Mahipal, A., Thiels, C., Jin...> ;JCO Precision Oncology. 2024 Jan 1
Postpartum related intrahepatic cholangiocarcinoma withfusion and severe hyperbilirubinemia with response to FGFR inhibitor pemigatinib: case report and review.
Washburn, L., Kottschade, L., Mahipal, A., Jatoi, A., Tran, N.> ;Journal of Gastrointestinal Oncology. 2023 Dec 31
Surgical Resection Alone is Associated With Higher Long-Term Survival Than Multiagent Chemotherapy Alone for Patients With Localized Biliary Tract Cancers.
Elshami, M., Selfridge, J., Ammori, J., Hardacre, J., Bajor, D., Mohamed, A., Chakrabarti, S., Mahipal, A., Winter, J., Ocuin, L.> ;The Journal of Surgical Research. 2024 Mar 1
3 citations
Targeted Therapies in Advanced Cholangiocarcinoma.
Michael H Storandt, Peter C Kurniali, Amit Mahipal, Zhaohui Jin> ;Life. 2023 Oct 16
Outcomes of Patients with Advanced Hepatocellular Carcinoma Receiving Lenvatinib following Immunotherapy: A Real World Evidence Study.
Mathias E Palmer, Michael H Storandt, Zhaohui Jin, Tyler J Zemla, Nguyen H Tran, Amit Mahipal, Jennifer J Gile> ;Cancers. 2023 Oct 6
Differences in the surgical management of early-stage hepatocellular carcinoma at minority versus non-minority-serving hospitals.
Mohamedraed Elshami, Lauryn Bailey, Richard S Hoehn, John B Ammori, Jeffrey M Hardacre, J Eva Selfridge, David Bajor, Amr Mohamed, Sakti Chakrabarti, Amit Mahipal, Jor...> ;Surgery. 2023 Nov 1
1 citations
Outcome of Patients With Early-Stage Mismatch Repair Deficient Colorectal Cancer Receiving Neoadjuvant Immunotherapy: A Systematic Review.
Sakti Chakrabarti, Udhayvir Singh Grewal, Kruti Bhagirath Vora, Aparna Raj Parikh, Diana Almader-Douglas, Amit Mahipal, Mohamad Bassam B Sonbol> ;JCO Precision Oncology. 2023 Aug 1
1 citations
Efficacy of Immune Checkpoint Inhibition and Cytotoxic Chemotherapy in Mismatch Repair-Deficient and Microsatellite Instability-High Pancreatic Cancer: Mayo Clinic Exp...
Tucker Coston, Aakash Desai, Hani Babiker, Mohamad Bassam Sonbol, Sakti Chakrabarti, Amit Mahipal, Robert McWilliams, Wen Wee Ma, Tanios S Bekaii-Saab, John Stauffer, ...> ;JCO Precision Oncology. 2023 Aug 1
1 citations
Impact of perioperative chemotherapy on survival in patients with cholangiocarcinoma undergoing curative resection.
Hind Hassan, Sakti Chakrabarti, Tyler Zemla, Jun Yin, Vanessa Wookey, Kritika Prasai, Amro Abdellatief, Renuka Katta, Nguyen Tran, Zhaohui Jin, Sean Cleary, Lewis Robe...> ;European Journal of Surgical Oncology. 2023 Nov 1
Disparities in guideline-compliant care for patients with pancreatic ductal adenocarcinoma at minority-versus non-minority-serving hospitals.
Mohamedraed Elshami, Richard S Hoehn, John B Ammori, Jeffrey M Hardacre, Jennifer E Selfridge, David Bajor, Amr Mohamed, Sakti Chakrabarti, Amit Mahipal, Jordan M Wint...> ;HPB. 2023 Dec 1
ASO Visual Abstact: NEO-GAP: A Single-Arm, Phase II Feasibility Trial of Neoadjuvant Gemcitabine, Cisplatin, and Nab-paclitaxel for Resectable, High-Risk Intrahepatic ...
Shishir K Maithel, Jessica M Keilson, Hop S Tran Cao, Manali Rupji, Amit Mahipal, Bruce S Lin, Milind M Javle, Sean P Cleary, Mehmet Akce, Jeffrey M Switchenko, Flavio...> ;Annals of Surgical Oncology. 2023 Oct 1
FOxTROT Study Results: Some Burning Questions Need Answers.
Sakti Chakrabarti, Amit Mahipal> ;Journal of Clinical Oncology. 2023 Oct 20
Completion of Genetic Testing and Incidence of Pathogenic Germline Mutation among Patients with Early-Onset Colorectal Cancer: A Single Institution Analysis.
Michael H Storandt, Kara R Rogen, Anushka Iyyangar, Rylie R Schnell, Jessica L Mitchell, Joleen M Hubbard, Frank A Sinicrope, Aminah Jatoi, Amit Mahipal, Qian Shi, Zha...> ;Cancers. 2023 Jul 11
1 citations
Tumor Mutational Burden in Real-World Patients With Pancreatic Cancer: Genomic Alterations and Predictive Value for Immune Checkpoint Inhibitor Effectiveness.
Julia C F Quintanilha, Michael H Storandt, Ryon P Graf, Gerald Li, Rachel Keller, Douglas I Lin, Jeffrey S Ross, Richard S P Huang, Alexa B Schrock, Geoffrey R Oxnard,...> ;JCO Precision Oncology. 2023 Jul 1
7 citations
NEO-GAP: A Single-Arm, Phase II Feasibility Trial of Neoadjuvant Gemcitabine, Cisplatin, and Nab-Paclitaxel for Resectable, High-Risk Intrahepatic Cholangiocarcinoma.
Shishir K Maithel, Jessica M Keilson, Hop S Tran Cao, Manali Rupji, Amit Mahipal, Bruce S Lin, Milind M Javle, Sean P Cleary, Mehmet Akce, Jeffrey M Switchenko, Flavio...> ;Annals of Surgical Oncology. 2023 Oct 1
Phase II Trial of Trifluridine/Tipiracil Plus Irinotecan in Patients with Advanced, Refractory Biliary Tract Carcinoma.
Sri Harsha Tella, Nathan Foster, Shi Qian, Tran Nguyen, Mitesh J Borad, Robert R McWilliams, Steven R Alberts, Wen Wee Ma, Sakti Chakrabarti, Briant Fruth, Jaclynn Wes...> ;The Oncologist. 2023 Oct 3
1 citations
The predictive impact of dual somatostatin receptor/fluorodeoxyglucose (FDG) positron emission tomography (PET) in metastatic gastroenteropancreatic neuroendocrine tum...
Amr Mohamed, Sylvia L Asa, Zhenghong Lee, Sree H Tirumani, Qiubai Li, Norbert Avril, David Bajor, Amit Mahipal, Sakti Chakrabarti, J Eva Selfridge, Arash Kardan> ;Journal of Gastrointestinal Oncology. 2023 Apr 29
ASO Visual Abstract: Cytoreduction with Hyperthermic Intraperitoneal Chemoperfusion for Pancreatic Cancer with Low-Volume Peritoneal Metastasis-Results from a Prospect...
Travis E Grotz, Jennifer A Yonkus, Cornelius A Thiels, Susanne G Warner, Robert McWilliams, Amit Mahipal, Tanios S Bekaii-Saab, Sean P Cleary, Michael L Kendrick, Mark...> ;Annals of Surgical Oncology. 2023 Sep 1
3 citations
A glimpse into the future of esophageal carcinoma in the United States: predicting the future incidence until 2040 based on the current epidemiological data.
Sri Harsha Tella, Kristin Mara, Sakti Chakrabarti, Zhaohui Jin, Amit Mahipal> ;Journal of Gastrointestinal Oncology. 2023 Feb 28
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Journal Articles

Systemic Therapy and Sequencing Options in Advanced Hepatocellular Carcinoma
Mohamad Bassam Sonbol, Amit Mahipal, Zhaohui Jin, Kabir Mody, Mitesh J Borad, Daniel H Ahn, Tanios Bekaii-Saab, JAMA Oncology
A Phase 2 Multi-Institutional Study of Nivolumab for Patients with Advanced Refractory Biliary Tract Cancer
Olatunji B Alese, Daneng Li, Amit Mahipal, JAMA Oncology

Authored Content

A Phase 2 Multi-Institutional Study of Nivolumab for Patients with Advanced Refractory Biliary Tract CancerMay 2020
A Phase 2 Multi-Institutional Study of Nivolumab for Patients with Advanced Refractory Biliary Tract CancerMay 2020