AmitJayantSabnisMD

PubMed

• 1 citations
  Clinical Targeted Next-Generation Panel Sequencing RevealsAmplification Is a Poor Prognostic Factor in Osteosarcoma.
  Amanda E Marinoff, Liam F Spurr, Christina Fong, Yvonne Y Li, Suzanne J Forrest, Abigail Ward, Duong Doan, Laura Corson, Audrey Mauguen, Navin Pinto, Luke Maese, Susan...> ;JCO Precision Oncology. 2023 Mar 1
• 5 citations
  GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma.
  Jacqueline Morales, David V Allegakoen, José A Garcia, Kristen Kwong, Pushpendra K Sahu, Drew A Fajardo, Yue Pan, Max A Horlbeck, Jonathan S Weissman, W Clay Gustafson...> ;JCI Insight. 2022 Dec 8
• 5 citations
  Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer.
  Lorena Lazo De La Vega, Hannah Comeau, Sarah Sallan, Alyaa Al-Ibraheemi, Hersh Gupta, Yvonne Y Li, Harrison K Tsai, Wenjun Kang, Abigail Ward, Alanna J Church, AeRang ...> ;JCO Precision Oncology. 2022 Nov 1
• 35 citations
  Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG).
  Ami V Desai, Giles W Robinson, Karen Gauvain, Ellen M Basu, Margaret E Macy, Luke Maese, Nicholas S Whipple, Amit J Sabnis, Jennifer H Foster, Suzanne Shusterman, Jane...> ;Neuro-Oncology. 2022 Oct 3
• 14 citations
  Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
  Alanna J Church, Laura B Corson, Pei-Chi Kao, Alma Imamovic-Tuco, Deirdre Reidy, Duong Doan, Wenjun Kang, Navin Pinto, Luke Maese, Theodore W Laetsch, AeRang Kim, Susa...> ;Nature Medicine. 2022 Aug 1
• 2 citations
  Clinical characteristics and outcomes of infants compared with children diagnosed with rhabdomyosarcoma: Analysis of surveillance, epidemiology and end results data fr...
  Hannah D Rees, Nancy K. Hills, Amit J. Sabnis, Asmin Tulpule, Tom K Shimotake, Robert E. Goldsby> ;Cancer Reports. 2021 Jul 13
• 8 citations
  Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor.
  Jaclyn Schienda, Alanna J Church, Laura B Corson, Brennan Decker, Catherine M Clinton, Danielle K Manning, Alma Imamovic-Tuco, Deirdre Reidy, Gianna R Strand, Mark A A...> ;JCO Precision Oncology. 2021 Jan 1
• 1 citations
  Germline MUTYH Mutation in a Pediatric Cancer Survivor Developing a Secondary Malignancy
  Vincent Lavergne, Amit J. Sabnis, Asmin Tupule, Philip R. Davidson, Cassie Kline, Katherine K. Matthay, Theodore Nicolaides, Robert E. Goldsby, Steve Braunstein, Shann...> ;Journal of Pediatric Hematology/oncology. 2020 Oct 1
• 7 citations
  Use of three-dimensional printing and intraoperative navigation in the surgical resection of metastatic acetabular osteosarcoma
  Julia Heunis, Jonathan W. Cheah, Amit J. Sabnis, Rosanna Wustrack> ;BMJ Case Reports. 2019 Sep 1
• 10 citations
  Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.
  Nilanjana Chatterjee, Evangelos Pazarentzos, Manasi K. Mayekar, Philippe Gui, David V. Allegakoen, Gorjan Hrustanovic, Victor Olivas, Luping Lin, Erik Verschueren, Jef...> ;Cell Reports. 2019 Aug 27
• 91 citations
  Principles of Resistance to Targeted Cancer Therapy: Lessons from Basic and Translational Cancer Biology.
  Amit J. Sabnis, Trever G. Bivona> ;Trends in Molecular Medicine. 2019 Mar 1
• 15 citations
  Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells
  Sara Sannino, Christopher J. Guerriero, Amit J. Sabnis, Donna B. Stolz, Callen T. Wallace, Peter Wipf, Simon C. Watkins, Trever G. Bivona, Jeffrey L. Brodsky> ;Journal of Cell Science. 2018 Jan 1
• 90 citations
  Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway
  Lukasz J. Bugaj, Amit J. Sabnis, Amir Mitchell, Joan E. Garbarino, Jared E. Toettcher, Trever G. Bivona, Wendell A. Lim> ;Science. 2018 Aug 31
• 4 citations
  Pulmonary veno-occlusive disease in a pediatric hematopoietic stem cell transplant patient: a cautionary tale.
  Matt S. Zinter, Alexis Melton, Amit J. Sabnis, Christopher C. Dvorak, Brett M. Elicker, Hythem Nawaytou, Rebecca J Kameny, Jeffrey R. Fineman> ;Leukemia & Lymphoma. 2018 Jun 1
• 30 citations
  EWSR1-NFATC2 gene fusion in a soft tissue tumor with epithelioid round cell morphology and abundant stroma: a case report and review of the literature
  Jarish N. Cohen, Amit J. Sabnis, Gregor Krings, Soo-Jin Cho, Andrew E. Horvai, Jessica L. Davis> ;Human Pathology. 2018 Apr 4
• 17 citations
  Reducing Second Gram-Negative Antibiotic Therapy on Pediatric Oncology and Hematopoietic Stem Cell Transplantation Services.
  Rachel L. Wattier, Emily R Levy, Amit J. Sabnis, Christopher C. Dvorak, Andrew D. Auerbach> ;Infection Control and Hospital Epidemiology. 2017 Jul 31
• 3 citations
  HSP70 dependence in rhabdomyosarcoma: Seed or soil?
  Amit J. Sabnis, Trever G. Bivona> ;Cell Cycle. 2017 Jan 17
• 3 citations
  Validation of high throughput screening of human sera for detection of anti-PA IgG by Enzyme-Linked Immunosorbent Assay (ELISA) as an emergency response to an anthrax ...
  Vera A. Semenova, Evelene Steward-Clark, Panagiotis Maniatis, Monica Epperson, Amit Sabnis, Jarad Schiffer> ;Biologicals. 2017 Jan 1
• 28 citations
  Combined chemical–genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma
  Amit J. Sabnis, Christopher J. Guerriero, Victor Olivas, Anin Sayana, Jonathan Shue, Jennifer Flanagan, Saurabh Asthana, Adrienne W. Paton, James C. Paton, Jason E. Ge...> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 Aug 9
• 201 citations
  RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.
  Gorjan Hrustanovic, Victor Olivas, Evangelos Pazarentzos, Asmin Tulpule, Saurabh Asthana, Collin M. Blakely, Ross A. Okimoto, Luping Lin, Dana S. Neel, Amit J. Sabnis,...> ;Nature Medicine. 2015 Sep 1
• 383 citations
  The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies
  Luping Lin, Amit J. Sabnis, Elton Chan, Victor Olivas, Lindsay Cade, Evangelos Pazarentzos, Saurabh Asthana, Dana S. Neel, Jenny Jiacheng Yan, Xinyuan Lu, Luu Pham, Mi...> ;Nature Genetics. 2015 Mar 1
• 14 citations
  Activating Mutations Cluster in the “Molecular Brake” Regions of Protein Kinases and Do Not Associate with Conserved or Catalytic Residues
  Miguel Angel Molina-Vila, Nuria Nabau-Moretó, Cristian Tornador, Amit J. Sabnis, Rafael Rosell, Xavier Estivill, Trever G. Bivona, Cristina Marino-Buslje> ;Human Mutation. 2014 Mar 1
• 6 citations
  FGFR Fusions in the Driver's Seat
  Amit J. Sabnis, Trever G. Bivona> ;Cancer Discovery. 2013 Jun 1
• A Continuous-Time, Discrete-State Method for Simulating the Dynamics of Biochemical Systems
  Amit Sabnis, Robert W. Harrison> ;IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2011 Mar 1
• 103 citations
  JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.
  Marianne Santaguida, Koen Schepers, Bryan H. King, Amit J. Sabnis, E. Camilla Forsberg, Joanne L. Attema, Benjamin S. Braun, Emmanuelle Passegué> ;Cancer Cell. 2009 Apr 7
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