AmyB.HeimbergerMD(She/Her)

PubMed

• Correction: Detecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients.
  Yongtao Wang, Wei Qiao, Chantal Reina-Ortiz, Mohamed K Abou-Ghazal, Lamonne M Crutcher, Jun Wei, Ling-Yuan Kong, William Humphries, Raymond Sawaya, Ganesh Rao, Jeffrey...> ;Journal of Translational Medicine. 2024 Mar 21
• Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.
  Kudruk, S., Forsyth, C., Dion, M., Hedlund Orbeck, J., Luo, J., Klein, R., Kim, A., Mirkin, C., Stegh, A., Artzi, N., Heimberger, A.> ;Proceedings of the National Academy of Sciences of the United States of America. 2024 Feb 20
• Prohibitin Expression in Antigen-Presenting Cells: Implications for Inciting Trigger in CNS IgG4-Related Disease.
  Hinda Najem, Victor A Arrieta, Joseph Duffy, Shashwat Tripathi, Markella Zannikou, Silpol Dhiantravan, Jason Miska, Kathleen McCortney, Alicia Steffens, Jordain Walsho...> ;Annals of Case Reports. 2024 Jan 1
• 2 citations
  Targeting Cytokines and Their Pathways for the Treatment of Cancer.
  Amy B Heimberger, Shashwat Tripathi, Leonidas C Platanias> ;Cancers. 2023 Oct 30
• 2 citations
  Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
  Mark W Youngblood, Zeynep Erson-Omay, Chang Li, Hinda Najem, Süleyman Coșkun, Evgeniya Tyrtova, Julio D Montejo, Danielle F Miyagishima, Tanyeri Barak, Sayoko Nishimur...> ;Nature Communications. 2023 Oct 7
• NUTMEG: A randomized phase II study of nivolumab and temozolomide versus temozolomide alone in newly diagnosed older patients with glioblastoma.
  Hao-Wen Sim, Luke Wachsmuth, Elizabeth H Barnes, Sonia Yip, Eng-Siew Koh, Merryn Hall, Ross Jennens, David M Ashley, Roel G Verhaak, Amy B Heimberger, Mark A Rosenthal...> ;Neuro-Oncology Advances. 2023 Sep 22
• 4 citations
  Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa.
  Xingsheng Ren, Laura D Manzanares, Enzo B Piccolo, Jessica M Urbanczyk, David P Sullivan, Lenore K Yalom, Triet M Bui, Connor Lantz, Hinda Najem, Parambir S Dulai, Amy...> ;The Journal of Clinical Investigation. 2023 Aug 1
• The Use of Targeted Cytokines as Cancer Therapeutics in Glioblastoma.
  Moloud Sooreshjani, Shashwat Tripathi, Corey Dussold, Hinda Najem, John de Groot, Rimas V Lukas, Amy B Heimberger> ;Cancers. 2023 Jul 23
• Immunobiology and Cytokine Modulation of the Pediatric Brain Tumor Microenvironment: A Scoping Review.
  Shreya Budhiraja, Hinda Najem, Shashwat Tripathi, Nitin R Wadhawani, Craig Horbinski, Matthew McCord, Alicia C Lenzen, Amy B Heimberger, Michael DeCuypere> ;Cancers. 2023 Jul 18
• 3 citations
  NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
  Abrar Choudhury, Martha A Cady, Calixto-Hope G Lucas, Hinda Najem, Joanna J Phillips, Brisa Palikuqi, Naomi Zakimi, Tara Joseph, Janeth Ochoa Birrueta, William C Chen,...> ;Biorxiv. 2023 Jul 11
• HER2+ esophageal carcinoma leptomeningeal metastases treated with intrathecal trastuzumab regimen.
  Scott A Wu, Dan Tong Jia, Margaret Schwartz, Mary Mulcahy, Kuanghua Guo, Matthew C Tate, Sean Sachdev, Nicolas Kostelecky, David J Escobar, Daniel J Brat, Amy B Heimbe...> ;CNS Oncology. 2023 Sep 1
• Advances in Blood-Brain Barrier Disruption to Facilitate Drug Delivery for Infiltrative Gliomas.
  Andrew Gould, Victor Andrés Arrieta Gonzales, Crismita Clement Dmello, Ruth Saganty, Rimas V Lukas, Daniel Y Zhang, Amy B Heimberger, Michael Canney, Alexandre Carpent...> ;Advances in Oncology. 2023 May 1
• 3 citations
  Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment.
  Luis G Fernandez, Ragini Yeeravalli, Crismita Dmello, Joseph T Duffy, Peng Zhang, Catalina Lee-Chang, Jason Miska, Atique U Ahmed, Adam M Sonabend, Irina V Balyasnikov...> ;Molecular Cancer Research. 2023 May 1
• 5 citations
  Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
  Crismita Dmello, Junfei Zhao, Li Chen, Andrew Gould, Brandyn Castro, Victor A Arrieta, Daniel Y Zhang, Kwang-Soo Kim, Deepak Kanojia, Peng Zhang, Jason Miska, Ragini Y...> ;Nature Communications. 2023 Mar 22
• 6 citations
  Determining venous thromboembolism risk in patients with adult-type diffuse glioma.
  Kirsten Bell Burdett, Dusten Unruh, Michael Drumm, Alicia Steffens, Jonathan Lamano, Jonathan Judkins, Margaret Schwartz, Rodrigo Javier, Christina Amidei, Eric S Lipp...> ;Blood. 2023 Mar 16
• 4 citations
  CXCR4 expression is associated with proneural-to-mesenchymal transition in glioblastoma.
  A Basit Khan, Sungho Lee, Akdes Serin Harmanci, Rajan Patel, Khatri Latha, Yuhui Yang, Anantha Marisetty, Hyun-Kyoung Lee, Amy B Heimberger, Gregory N Fuller, Benjamin...> ;International Journal of Cancer. 2023 Feb 15
• 17 citations
  Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma.
  Lizhi Pang, Madeline Dunterman, Wenjing Xuan, Annette Gonzalez, Yiyun Lin, Wen-Hao Hsu, Fatima Khan, Robert S Hagan, William A Muller, Amy B Heimberger, Peiwen Chen> ;Cell Reports. 2023 Feb 28
• 2 citations
  FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells.
  Qingnan Zhao, Jiemiao Hu, Lingyuan Kong, Shan Jiang, Xiangjun Tian, Jing Wang, Rintaro Hashizume, Zhiliang Jia, Natalie Wall Fowlkes, Jun Yan, Xueqing Xia, Sofia F Yi,...> ;Nature Communications. 2023 Feb 10
• 1 citations
  A Case Study of Chimeric Antigen Receptor T Cell Function: Donor Therapeutic Differences in Activity and Modulation with Verteporfin.
  Jiyong Liang, Dexing Fang, Joy Gumin, Hinda Najem, Moloud Sooreshjani, Renduo Song, Aria Sabbagh, Ling-Yuan Kong, Joseph Duffy, Irina V Balyasnikova, Seth M Pollack, V...> ;Cancers. 2023 Feb 8
• 1 citations
  Novel murine glioblastoma models that reflect the immunotherapy resistance profile of a human disease.
  Chao-Hsien Chen, Renee L Chin, Genevieve P Hartley, Spencer T Lea, Brian J Engel, Cheng-En Hsieh, Rishika Prasad, Jason Roszik, Takashi Shingu, Gregory A Lizee, Amy B ...> ;Neuro-Oncology. 2023 Aug 3
• 29 citations
  Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment.
  Víctor A Arrieta, Crismita Dmello, Daniel J McGrail, Daniel J Brat, Catalina Lee-Chang, Amy B Heimberger, Dhan Chand, Roger Stupp, Adam M Sonabend> ;The Journal of Clinical Investigation. 2023 Jan 17
• Antigen-presenting B cells promote TCF-1PD1stem-like CD8T-cell proliferation in glioblastoma.
  David Hou, Hanxiao Wan, Joshua L Katz, Si Wang, Brandyn A Castro, Gustavo I Vazquez-Cervantes, Victor A Arrieta, Silpol Dhiantravan, Hinda Najem, Aida Rashidi, Tzu-Yi ...> ;Frontiers in Immunology. 2023 Jan 1
• 3 citations
  Clinical Management of Supratentorial Non-Skull Base Meningiomas.
  Adefisayo Adekanmbi, Mark W Youngblood, Constantine L Karras, Ephraim A Oyetunji, John Kalapurakal, Craig M Horbinski, Hinda Najem, Virginia B Hill, James P Chandler, ...> ;Cancers. 2022 Nov 29
• 3 citations
  Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay.
  D J McGrail, P G Pilié, N U Rashid, L Voorwerk, M Slagter, M Kok, E Jonasch, M Khasraw, A B Heimberger, N T Ueno, R Ferrarotto, J T Chang, S-Y Lin> ;Annals of Oncology. 2022 Nov 1
• 5 citations
  Fibrinogen-like protein 2: Its biological function across cell types and the potential to serve as an immunotherapy target for brain tumors.
  Sheng Zhang, Ganesh Rao, Amy Heimberger, Shulin Li> ;Cytokine & Growth Factor Reviews. 2023 Feb 1
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Journal Articles

• Profiles of Brain Metastases: Prioritization of Therapeutic Targets  
  Raymond Sawaya, Zoran Gatalica, Isabella C Glitza, John V Heymach, Michael E Salacz, Michael A Davies, Amy B Heimberger, Nuhad K Ibrahim, Jianjun Zhang, Sherise D Ferg..., International Journal of Cancer

Lectures

• Antitumor Immune-Inducing Strategies for Glioblastoma 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/1/2018