AnandSDigheMD

Pathology • Boston, MA

Anatomic Pathology, Clinical Pathology

Associate Professor of Pathology, Massachusetts General Hospital

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Office
55 Fruit St
Grb 535b
Boston, MA 02114
Phone+1 617-726-7902

Fax+1 617-726-9206
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Education & Training

Massachusetts General HospitalResidency, Pathology-Anatomic and Clinical, 1999 - 2001
Washington University in St. Louis School of MedicineClass of 1996

Certifications & Licensure

MA State Medical License 2001 - 2026
American Board of Pathology Clinical Pathology
American Board of Pathology Clinical Informatics

Publications & Presentations

PubMed

Clinical decision support to improve CBC and differential ordering.
Grace K Mahowald, Kent B Lewandrowski, Anand S Dighe> ;American Journal of Clinical Pathology. 2024 Mar 20
Clinical Decision Support in Laboratory Medicine.
Kay Weng Choy, Pieter Cornu, Anand S Dighe, Andrew Georgiou, Lindsay Peters, Kenneth A Sikaris, Tze Ping Loh> ;Clinical Chemistry. 2024 Mar 2
Using machine learning to develop smart reflex testing protocols.
Matthew McDermott, Anand Dighe, Peter Szolovits, Yuan Luo, Jason Baron> ;Journal of the American Medical Informatics Association. 2024 Jan 18
2 citations
Delayed and Attenuated Antibody Responses to Coronavirus Disease 2019 Vaccination With Poor Cross-Variant Neutralization in Solid-Organ Transplant Recipients-A Prospec...
May Y Liew, Josh I Mathews, Amy Li, Rohan Singh, Salvador A Jaramillo, Zoe F Weiss, Kathryn Bowman, Pierre O Ankomah, Fadi Ghantous, Gregory D Lewis, Isabel Neuringer,...> ;Open Forum Infectious Diseases. 2023 Aug 1
1 citations
Electronic Health Record Optimization for Artificial Intelligence.
Anand S Dighe> ;Clinics in Laboratory Medicine. 2023 Mar 1
Using Machine Learning to Develop Smart Reflex Testing Protocols.
Matthew McDermott, Anand Dighe, Peter Szolovits, Yuan Luo, Jason Baron> ;Arxiv. 2023 Feb 1
Use of Clinical Decision Support to Improve the Laboratory Evaluation of Monoclonal Gammopathies.
Daniel S Pearson, Dustin S McEvoy, Mandakolathur R Murali, Anand S Dighe> ;American Journal of Clinical Pathology. 2023 Feb 1
41 citations
Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Marta Broto, Michael M Kaminski, Christopher Adrianus, Nayoung Kim, Robert Greensmith, Schan Dissanayake-Perera, Alexander J Schubert, Xiao Tan, Hyemin Kim, Anand S Di...> ;Nature Nanotechnology. 2022 Oct 1
3 citations
Clinical decision support improves blood culture collection before intravenous antibiotic administration in the emergency department.
Sayon Dutta, Dustin S McEvoy, David M Rubins, Anand S Dighe, Michael R Filbin, Chanu Rhee> ;Journal of the American Medical Informatics Association. 2022 Sep 12
11 citations
Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency.
Sara Barmettler, Daniel V DiGiacomo, Nancy J Yang, Tiffany Lam, Vivek Naranbhai, Anand S Dighe, Kristin E Burke, Kimberly G Blumenthal, Morris Ling, Paul E Hesterberg,...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Jun 1
8 citations
The Effect of Vaccine Type and SARS-CoV-2 Lineage on Commercial SARS-CoV-2 Serologic and Pseudotype Neutralization Assays in mRNA Vaccine Recipients.
Nicole V Tolan, Amy C Sherman, Guohai Zhou, Katherine G Nabel, Michaël Desjardins, Stacy Melanson, Sanjat Kanjilal, Serina Moheed, John Kupelian, Richard M Kaufman, Ed...> ;Microbiology Spectrum. 2022 Apr 27
77 citations
Comparative Immunogenicity and Effectiveness of mRNA-1273, BNT162b2, and Ad26.COV2.S COVID-19 Vaccines.
Vivek Naranbhai, Wilfredo F Garcia-Beltran, Christina C Chang, Cristhian Berrios Mairena, Julia C Thierauf, Grace Kirkpatrick, Maristela L Onozato, Ju Cheng, Kerri J S...> ;The Journal of Infectious Diseases. 2022 Apr 1
13 citations
Humoral and cellular immunogenicity of SARS-CoV-2 vaccines in chronic lymphocytic leukemia: a prospective cohort study.
J Erika Haydu, Jenny S Maron, Robert A Redd, Kathleen M E Gallagher, Stephanie Fischinger, Jeffrey A Barnes, Ephraim P Hochberg, P Connor Johnson, R W Takvorian, Katel...> ;Blood Advances. 2022 Mar 22
56 citations
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
Katherine G Nabel, Sarah A. Clark, Sundaresh Shankar, Junhua Pan, Lars Clark, Pan Yang, Adrian Coscia, Lindsay G. A. McKay, Haley H Varnum, Vesna Brusic, Nicole V. Tol...> ;Science. 2021 Dec 2
59 citations
Immunogenicity and Reactogenicity of SARS-CoV-2 Vaccines in Patients With Cancer: The CANVAX Cohort Study.
Vivek Naranbhai, Claire A. Pernat, Alexander Gavralidis, Kerri St. Denis, Evan C. Lam, Laura Spring, Steven J. Isakoff, Jocelyn R. Farmer, Leyre Zubiri, Gabriela S. Ho...> ;Journal of Clinical Oncology. 2021 Nov 9
20 citations
Determining the Incidence of Asymptomatic SARS-CoV-2 among Early Recipients of COVID-19 Vaccines: A Prospective Cohort Study of Healthcare Workers before, during and a...
Crystal M. North, Amy K. Barczak, Robert H. Goldstein, Brian C. Healy, Dianne M. Finkelstein, Delaney D Ding, Andrew J. Kim, Julie Boucau, Bennett M. Shaw, Rebecca F G...> ;Clinical Infectious Diseases. 2021 Aug 7
31 citations
Immunogenicity of mRNA-1273, BNT162b2 and Ad26.COV2.S COVID-19 vaccines
Vivek Naranbhai, Wilfredo F. Garcia-Beltran, Christhian Berrios Mairena, Julia Thierauf, Christina C. Chang, Grace Kirkpatrick, Maristela L. Onozato, Ju Cheng, Kerri S...> ;Medrxiv. 2021 Oct 13
408 citations
COVID-19-neutralizing antibodies predict disease severity and survival.
Wilfredo F. Garcia-Beltran, Evan C. Lam, Michael G Astudillo, Diane Yang, Tyler E. Miller, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Kiera L. Clayton, Adam...> ;Cell. 2021 Jan 21
7 citations
Use of machine learning to predict clinical decision support compliance, reduce alert burden, and evaluate duplicate laboratory test ordering alerts
Jason M. Baron, Richard Huang, Dustin McEvoy, Anand S. Dighe> ;JAMIA Open. 2021 Mar 1
36 citations
Evaluation of Three Commercial SARS-CoV-2 Serologic Assays and Their Performance in Two-Test Algorithms.
Sarah E Turbett, Melis N. Anahtar, Anand S. Dighe, Wilfredo F. Garcia Beltran, Tyler E. Miller, Hannah Scott, Sienna Durbin, Maheetha Bharadwaj, Jason Thomas, Tasos Go...> ;Journal of Clinical Microbiology. 2020 Dec 17
8 citations
Remote Fingerstick Blood Collection for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Testing.
Wilfredo F. Garcia-Beltran, Tyler E. Miller, Grace Kirkpatrick, Andrea L. Nixon, Michael G Astudillo, Diane Yang, Lisa M Mahanta, Mandakolathur R. Murali, Anand S. Dig...> ;Archives of Pathology & Laboratory Medicine. 2021 Apr 1
181 citations
COVID-19 neutralizing antibodies predict disease severity and survival
Wilfredo F. Garcia-Beltran, Evan C. Lam, Michael G Astudillo, Diane Yang, Tyler E. Miller, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Kiera L. Clayton, Adam...> ;Medrxiv. 2020 Oct 20
10 citations
Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest
Elazer R. Edelman, Neel M. Butala, Laura L. Avery, Andrew L. Lundquist, Anand S. Dighe> ;The New England Journal of Medicine. 2020 Sep 23
93 citations
Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.
Tyler E. Miller, Wilfredo F. Garcia Beltran, Adam Z. Bard, Tasos Gogakos, Melis N. Anahtar, Michael G Astudillo, Diane Yang, Julia Thierauf, Adam S. Fisch, Grace K. Ma...> ;FASEB Journal. 2020 Aug 28
4 citations
Iron studies and transferrin, a source of test ordering confusion highly amenable to clinical decision support
Richard Huang, Dustin McEvoy, Jason M. Baron, Anand S. Dighe> ;Clinica Chimica Acta; International Journal of Clinical Chemistry. 2020 Jul 17
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Journal Articles

Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest
Elazer R Edelman, Laura L Avery, Anand S Dighe, The New England Journal of Medicine
Creation and Use of an Electronic Health Record Reporting Database to Improve a Laboratory Test Utilization Program
Joseph W Rudolf, Anand S Dighe, Kent B Lewandrowski, Jason M Baron, Applied Clinical Informatics

Press Mentions

Clinical Pathology Selected AbstractsApril 20th, 2023
From the President’s DeskApril 20th, 2023
Can Machine Learning Algorithms Predict Lab Values?February 1st, 2020
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Hospital Affiliations

Massachusetts General HospitalBoston, Massachusetts