AnnCMcKeeMD

PubMed

• Lack of Association of Informant-Reported Traumatic Brain Injury and Chronic Traumatic Encephalopathy.
  Uretsky, M., Julia E Culhane, Colleen E Jackson, Yorghos Tripodis, Christopher J Nowinski, Kristen Dams-O'Connor, Erika Pettway, Madeline Uretsky, Bobak Abdolmohammadi...> ;Journal of Neurotrauma. 2024 Apr 15
• 1 citations
  Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project.
  Yi Su, Hillary Protas, Ji Luo, Kewei Chen, Michael L Alosco, Charles H Adler, Laura J Balcer, Charles Bernick, Rhoda Au, Sarah J Banks, William B Barr, Michael J Colem...> ;Alzheimer's & Dementia. 2024 Mar 1
• Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE.
  Alexander, A., Alvarez, V., Huber, B., Alosco, M., Mez, J., Tripodis, Y., Nicks, R., Katz, D., Dwyer, B., Daneshvar, D., Martin, B., Palmisano, J., Goldstein, L., Crar...> ;Acta Neuropathologica. 2024 Feb 26
• 4 citations
  Relative Contributions of Mixed Pathologies to Cognitive and Functional Symptoms in Brain Donors Exposed to Repetitive Head Impacts.
  Nicole Saltiel, Yorghos Tripodis, Talia Menzin, Aliyah Olaniyan, Zach Baucom, Eukyung Yhang, Joseph N Palmisano, Brett Martin, Madeline Uretsky, Evan Nair, Bobak Abdol...> ;Annals of Neurology. 2024 Feb 1
• 11 citations
  Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts.
  Ann C McKee, Jesse Mez, Bobak Abdolmohammadi, Morgane Butler, Bertrand Russell Huber, Madeline Uretsky, Katharine Babcock, Jonathan D Cherry, Victor E Alvarez, Brett M...> ;JAMA Neurology. 2023 Oct 1
• 2 citations
  American Football Play and Parkinson Disease Among Men.
  Hannah J Bruce, Yorghos Tripodis, Michael McClean, Monica Korell, Caroline M Tanner, Brittany Contreras, Joshua Gottesman, Leslie Kirsch, Yasir Karim, Brett Martin, Jo...> ;JAMA Network Open. 2023 Aug 1
• 1 citations
  Inflammation and neuronal gene expression changes differ in early versus late chronic traumatic encephalopathy brain.
  Adam Labadorf, Filisia Agus, Nurgul Aytan, Jonathan Cherry, Jesse Mez, Ann McKee, Thor D Stein> ;BMC Medical Genomics. 2023 Mar 9
• 23 citations
  Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts.
  Ann C McKee, Thor D Stein, Bertrand R Huber, John F Crary, Kevin Bieniek, Dennis Dickson, Victor E Alvarez, Jonathan D Cherry, Kurt Farrell, Morgane Butler, Madeline U...> ;Acta Neuropathologica. 2023 Apr 1
• 8 citations
  Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis.
  Raymond Nicks, Nathan F Clement, Victor E Alvarez, Yorghos Tripodis, Zachery H Baucom, Bertrand R Huber, Jesse Mez, Michael L Alosco, Nurgul Aytan, Jonathan D Cherry, ...> ;Acta Neuropathologica. 2023 Apr 1
• 7 citations
  Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy.
  Daniel Kirsch, Arsal Shah, Erin Dixon, Hunter Kelley, Jonathan D Cherry, Weiming Xia, Sarah Daley, Nurgul Aytan, Kerry Cormier, Carol Kubilus, Rebecca Mathias, Victor ...> ;Journal of Neuropathology and Experimental Neurology. 2023 Jan 20
• 3 citations
  Decreased myelin proteins in brain donors exposed to football-related repetitive head impacts.
  Uretsky, M., Michael L Alosco, Monica Ly, Sydney Mosaheb, Nicole Saltiel, Madeline Uretsky, Yorghos Tripodis, Brett Martin, Joseph Palmisano, Lisa Delano-Wood, Mark W ...> ;Brain Communications. 2023 Jan 1
• 4 citations
  Volumetric Characterization of Microvasculature in Ex Vivo Human Brain Samples By Serial Sectioning Optical Coherence Tomography.
  Jiarui Yang, Shuaibin Chang, Ichun Anderson Chen, Sreekanth Kura, Grace A Rosen, Nicole A Saltiel, Bertrand R Huber, Divya Varadarajan, Yael Balbastre, Caroline Magnai...> ;IEEE Transactions on Bio-Medical Engineering. 2022 Dec 1
• 1 citations
  Neuroimmune proteins can differentiate between tauopathies.
  Jonathan D Cherry, Zach H Baucom, Kaleb G Eppich, Daniel Kirsch, Erin R Dixon, Yorghos Tripodis, Kevin F Bieniek, Kurt Farrell, Kristen Whitney, Madeline Uretsky, John...> ;Journal of Neuroinflammation. 2022 Nov 19
• 10 citations
  Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players.
  Michael L Alosco, Yi Su, Thor D Stein, Hillary Protas, Jonathan D Cherry, Charles H Adler, Laura J Balcer, Charles Bernick, Surya Vamsi Pulukuri, Bobak Abdolmohammadi,...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2023 Jan 1
• 12 citations
  Interpretable deep learning of myelin histopathology in age-related cognitive impairment.
  Andrew T McKenzie, Gabriel A Marx, Daniel Koenigsberg, Mary Sawyer, Megan A Iida, Jamie M Walker, Timothy E Richardson, Gabriele Campanella, Johannes Attems, Ann C McK...> ;Acta Neuropathologica Communications. 2022 Sep 21
• 7 citations
  Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy.
  Kurt Farrell, Megan A Iida, Jonathan D Cherry, Alicia Casella, Thor D Stein, Kevin F Bieniek, Jamie M Walker, Timothy E Richardson, Charles L White, Victor E Alvarez, ...> ;Journal of Neuropathology and Experimental Neurology. 2022 Sep 19
• 10 citations
  White matter hyperintensities in former American football players.
  Michael L Alosco, Yorghos Tripodis, Zachary H Baucom, Charles H Adler, Laura J Balcer, Charles Bernick, Megan L Mariani, Rhoda Au, Sarah J Banks, William B Barr, Jenni...> ;Alzheimer's & Dementia. 2023 Apr 1
• 29 citations
  Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy.
  Shanu F Roemer, Lea T Grinberg, John F Crary, William W Seeley, Ann C McKee, Gabor G Kovacs, Thomas G Beach, Charles Duyckaerts, Isidro A Ferrer, Ellen Gelpi, Edward B...> ;Acta Neuropathologica. 2022 Oct 1
• 19 citations
  Association of APOE Genotypes and Chronic Traumatic Encephalopathy.
  Kathryn Atherton, Xudong Han, Jaeyoon Chung, Jonathan D Cherry, Zachary Baucom, Nicole Saltiel, Evan Nair, Bobak Abdolmohammadi, Madeline Uretsky, Mohammed Muzamil Kha...> ;JAMA Neurology. 2022 Aug 1
• 5 citations
  Alzheimer's disease amyloid-β pathology in the lens of the eye.
  Juliet A Moncaster, Robert D Moir, Mark A Burton, Oliver Chadwick, Olga Minaeva, Victor E Alvarez, Maria Ericsson, John I Clark, Ann C McKee, Rudolph E Tanzi, Lee E Go...> ;Experimental Eye Research. 2022 Aug 1
• 11 citations
  Tau Pathology in Chronic Traumatic Encephalopathy is Primarily Neuronal.
  Morgane L M D Butler, Erin Dixon, Thor D Stein, Victor E Alvarez, Bertrand Huber, Michael E Buckland, Ann C McKee, Jonathan D Cherry> ;Journal of Neuropathology and Experimental Neurology. 2022 Sep 19
• 5 citations
  Relationship Between Level of American Football Playing and Diagnosis of Chronic Traumatic Encephalopathy in a Selection Bias Analysis.
  Jessica LeClair, Jennifer Weuve, Matthew P Fox, Jesse Mez, Michael L Alosco, Chris Nowinski, Ann McKee, Yorghos Tripodis> ;American Journal of Epidemiology. 2022 Jul 23
• 2 citations
  Non-Targeted Metabolomics Approach Revealed Significant Changes in Metabolic Pathways in Patients with Chronic Traumatic Encephalopathy.
  Jinkyung Lee, Suhyun Kim, Yoon Hwan Kim, Uiyeol Park, Junghee Lee, Ann C McKee, Kyoung Heon Kim, Hoon Ryu, Jeongae Lee> ;Biomedicines. 2022 Jul 15
• 9 citations
  Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease.
  Brandon Frank, Madeline Ally, Yorghos Tripodis, Christian Puzo, Caroline Labriola, Landon Hurley, Brett Martin, Joseph Palmisano, Lawrence Chan, Eric Steinberg, Kather...> ;Neurology. 2022 Jun 14
• Utility of the ALSFRS-R for predicting ALS and comorbid disease neuropathology: The Veterans Affairs Biorepository Brain Bank.
  Leigh E Colvin, Zachariah W Foster, Thor D Stein, Manisha Thakore-James, Mohammad Kian Salajegheh, Kendall Carr, Keith R Spencer, Nazifa Abdul Rauf, Latease Adams, Jam...> ;Muscle & Nerve. 2022 Aug 1
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Journal Articles

• Astrocytic Degeneration in Chronic Traumatic Encephalopathy  
  David L Brody, Thor D Stein, Ann C McKee, Acta Neuropathologica
• Frequency of head impact related outcomes by position in NCAA Division I collegiate football players  
  Baugh CM, Kiernan PT, Kroshus E, Daneshvar DH, Montenigro PH, McKee AC, Stern R, J Neurotrauma, 8/26/2014
• Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer's disease  
  Saman S, Lee NC, Inoyo I, Jin J, Li Z, Doyle T, McKee AC, Hall GF, J Alzheimers Dis, 1/1/2014
• 1R-flurbiprofen improves tau, but not Abeta pathology in a triple transgenic model of Alzheimer's disease  
  Carreras I, McKee AC, Choi JK, Aytan N, Kowall NW, Jenkins BG, Dedeoglu A, Brain Res, 12/1/2013
• Lexical retrieval in discourse: An early indicator of Alzheimer's dementia  
  Pekkala S, Wiener D, Himali JJ, Beiser AS, Obler LK, Liu Y, McKee A, Auerbach S, Seshadri S, Wolf PA, Au R, Clin Linguist Phon, 8/28/2013
• Clinical presentation of chronic traumatic encephalopathy  
  Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Buds..., Neurology, 8/21/2013
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  Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR..., JAMA, 4/1/2013
• Multiple mechanisms of extracellular tau spreading in a non-transgenic tauopathy model  
  Le M, Kim W, Lee S, McKee A, Hall G, Am J Neurodegeneration, 11/25/2012
• Expression of Taurine Transporter (TauT) is Modulated by Heat Shock Factor 1 (HSF1) in Motor Neurons of ALS  
  Jung MK, Kim KY, Lee NY, Kang YS, Hwang YJ, Kim Y, Sung JJ, McKee A, Kowall N, Lee J, Ryu H, Mol Neurobiol, 11/23/2012
• Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma  
  Baugh CM, Stamm JM, Riley DO, Gavett BE, Shenton ME, Lin A, Nowinski CJ, Cantu RC, McKee AC, Stern RA, Brain Imaging Behav, 6/1/2012
• Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature Review  
  Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulet..., J Neuropathol Exp Neurol, 5/1/2012
• Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease  
  Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF, J Biol Chem, 2/1/2012
• Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue  
  Liu-Yesucevitz L, Bilgutay A, Zhang YJ, Vanderwyde T, Citro A, Mehta T, Zaarur N, McKee A, Bowser R, Sherman M, Petrucelli L, Wolozin B, PLoS One, 10/1/2011
• Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy Review  
  Stern RA, Riley DO, Daneshvar DH, Nowinski CJ, Cantu RC, McKee AC, PMR, 10/1/2011
• Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice  
  Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H, Acta Neuropathol, 4/1/2011
• Chronic Traumatic Encephalopathy: A Potential Late Effect of Sport-Related Concussive and Subconcussive Head Trauma  
  Gavett B, Stern R. McKee A, Clinics in Sports Medicine, 1/1/2011
• Helmets and Mouth guards: The Role of Personal Equipment in Preventing Sports Related Concussions  
  Daneshvar D, Nowinski C, McKee A, Stern R, Cantu R, Clinics in Sports Medicine, 1/1/2011
• The Epidemiology of Sports-Related Concussion  
  Daneshvar D, Nowinski C, McKee A, Cantu R, Clinics in Sports Medicine, 1/1/2011
• Mild traumatic brain injury: A risk factor for neurodegeneration  
  Gavett, B, Stern R, Cantu R, Nowinski C, McKee A, Alzheimer's Research and Therapy, 6/1/2010
• TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy  
  McKee A, Gavett B, Stern R, Nowinski C, Cantu R, Kowall N, Perl D, Hedley-Whyte E, Price B, Sullivan C, Morin P, Lee H-S, Kubilus C, Daneshvar D, Wulff M, Budson A, Journal Neuropathol Exp Neurol, 1/1/2010
• Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease  
  Mastroeni D, McKee A, Grover A, Rogers J, Coleman PD, PLoS One, 8/1/2009
• Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy following Repetitive Head Injury  
  McKee AC, Cantu RC, Nowinski CJ, Hedley-Whyte ET, Gavett BE, Budson AE, Santini VE, Lee H-Y, Kubilus CA, Stern RA, J Neuropath Exp Neurol, 1/1/2009
• Ibuprofen reduces intraneuronal ABeta, prevents hyperphosphorylated tau and ameliorates cognitive deficits in young triple transgenic Alzheimer mice  
  McKee AC, Carreras I, Hossain L, Ryu H, Klein W, Oddo S, LaFerla F, Jenkins B, Kowall N, Dedeoglu A, Brain Research, 5/1/2008
• Sepiapterin reductase expression is increased in Parkinson's disease brain tissue  
  Tobin JE, Cui J, Wilk J, Latourelle J, Laramie J, McKee A, Guttman M, Karamohamed S, DeStefano A, Myers R, Brain Research, 1/1/2007
• Insulin degrading enzyme is localized predominantly in the cell surface of polarized and unpolarized human cerebrovascular endothelial cultures  
  Lynch JA, George AM, Eisenhauer PB, Conn K, Gao W, Carreras I, Wells J, McKee A, Ullman D, Fine RE, J Neurosci Res, 5/1/2006
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Books/Book Chapters

• lzheimer’s disease and other dementias, Behavioral Neuroscience Series 
  Chapter: The Neuropathology of Dementia 
  McKee Ann CEditors: Budson, A.2011
• Neural Injury and Regeneration 
  Chapter: The histopathology of degeneration and plasticity in Alzheimer's disease 
  Kowall NW, McKee ACEditors: Seil F.1993
• Atlas of Diagnostic Oncology 
  Chapter: Neoplasms of the Central Nervous System 
  McKee ACEditors: Skarin A.Gower Medical Publishing, New York, NYEdition 1st,1990

Lectures

• Emerging Concepts in CTE 
  Cleveland, OH - 10/16/2014
• CTE –emerging concepts 
  Sao Paulo, Brazil - 9/19/2014
• CTE: current concepts 
  Sao Paulo, Brazil - 9/15/2014
• Current concepts in CTE 
  New Orleans, LA - 5/20/2014
• Pathology of CTE 
  Philadelphia, PA - 5/3/2014
• What is CTE? 
  Appleton High School East, Appleton, WI - 4/7/2014
• Update on CTE in athletes 
  Eau Claire, WI - 4/4/2014
• Emerging Concepts in Chronic Traumatic Encephalopathy 
  Vanderbilt University, Nashville, TN - 11/18/2013
• Prospective Study of CTE using Neuro Imaging with Post Mortem as a Final Validation/Challenges 
  Rochester, MN - 10/8/2013
• Chronic Traumatic Encephalopathy in Athletes and Veterans 
  Boston, MA - 5/23/2013
• Update on Chronic Traumatic Encephalopathy 
  Boston, MA - 5/18/2013
• Ocular Manifestations of Chronic Traumatic Encephalopathy 
  Seattle, WA - 5/5/2013
• Chronic post-traumatic encephalopathy in professional sport 
  Hamilton, Ontario, Canada - 4/19/2013
• Brain Damage and Recovery 
  Atlanta, GA - 4/11/2013
• What is the pathological evidence for concussion related changes in the brains of retired athletes? 
  Zurich, Switzerland - 11/2/2012
• Chronic Traumatic Encephalopathy 2012 
  Scottsdale, AZ - 9/28/2012
• Chronic Traumatic Encephalopathy in the Military 
  Fort Lauderdale, FL - 8/15/2012
• Chronic Traumatic Encephalopathy: What we have learned from athletes and Veterans 
  New York, NY - 4/17/2012
• The Long-term Consequences of Repetitive Concussion 
  Appleton High School East, Appleton, WI - 3/5/2012
• Mild Traumatic Brain Injury and Chronic Traumatic Encephalopathy: What we have learned from athletes 
  Oakbrook, IL - 10/29/2011
• Recurrent Athletic mTBI, Cerebral Tauopathy, and Chronic Traumatic Encephalopathy 
  Philadelphia, PA - 10/21/2011
• The Long-term Sequelae of Mild Traumatic Brain Injury 
  Washington, DC - 8/22/2011
• Traumatic Brain Injury 
  Woods Hole, MA - 8/16/2011
• Chronic Traumatic Encephalopathy: Your brain on football 
  Oak Lawn, IL - 5/11/2011
• University of Edinboro Concussion Conference 
  Edinboro, PA - 4/29/2011
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