AnnJMelvinMD

Pediatric Infectious Disease • Seattle, WA

Physician

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Office
4800 Sand Point Way Ne
Seattle, WA 98105
Phone+1 206-987-2000
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Education & Training

University of WashingtonFellowship, Pediatric Infectious Diseases, 1990 - 1993
University of California (San Francisco)Residency, Pediatrics, 1986 - 1987
Tulane University School of MedicineClass of 1986

Certifications & Licensure

WA State Medical License 1988 - 2024
LA State Medical License 1986 - 1987
American Board of Pediatrics Pediatric Infectious Diseases

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Anti-HIV Drug Regimens and Treatment-Switching Guidelines in HIV Infected Children Start of enrollment: 2002 Aug 01
Completed
Phase 2, Phase 3
A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy
Completed
Phase 2
IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia Start of enrollment: 2009 Aug 01
Terminated
Phase 1, Phase 2
Safety, Tolerability, Drug Interactions, and Antiviral Activity of Rilpivirine in Antiretroviral-Naive HIV-Infected Children Less Than 12 Years of Age Start of enrollment: 2014 Sep 01
Withdrawn
Phase 1, Phase 2
Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants Start of enrollment: 2018 Aug 31
Active, not recruiting
Phase 2
Adolescent Master Protocol for Participants 18 Years of Age or Older - Lite Start of enrollment: 2017 Nov 01
Recruiting
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Publications & Presentations

PubMed

Efficacy, Safety, and Tolerability of Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Fixed-Dose Combination Tablets in Adolescents Living With HIV: Results Throug...
Supattra Rungmaitree, Linda Aurpibul, Brookie M Best, Xiang Li, Meredith G Warshaw, Hong Wan, Nicole H Tobin, Patricia Jumes, Randi Leavitt, Katie McCarthy, Rachel Sch...> ;Journal of the Pediatric Infectious Diseases Society. 2023 Dec 16
1 citations
A Cross-Sectional Survey of Pediatric Infectious Disease Physicians' Approach to Congenital Cytomegalovirus Infection.
Chieko Hoki, Michelle White, Megan H Pesch, Ann J Melvin, Albert H Park> ;International Journal of Neonatal Screening. 2023 Mar 24
Pharmacokinetics, Tolerability, and Safety of Doravirine and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Fixed-Dose Combination Tablets in Adolescents Living W...
Ann J Melvin, Ka Lai Yee, Kathryn P Gray, Mounika Yedla, Hong Wan, Nicole H Tobin, Hedy Teppler, Havilland Campbell, Katie McCarthy, Rachel Scheckter, Linda Aurpibul, ...> ;Journal of Acquired Immune Deficiency Syndromes. 2023 Feb 1
HIV Transmission Through Premastication.
Sarah H Nash, Molly Rutledge, Lisa M Frenkel, Ann J Melvin, Peyton Laws, Joseph Klejka, Matthew Hirschfeld> ;Pediatrics. 2022 Oct 1
16 citations
Neonatal Herpes Simplex Virus Infection: Epidemiology and Outcomes in the Modern Era.
Ann J Melvin, Kathleen M Mohan, Surabhi B Vora, Stacy Selke, Erin Sullivan, Anna Wald> ;Journal of the Pediatric Infectious Diseases Society. 2022 Mar 24
Institutionally chartered Data and Safety Monitoring Boards: structured approaches to assuring participant safety in clinical research.
Blair Holbein, Marie Rape, Barbara N. Hammack, Ann J. Melvin, Carson Reider, Tamsin A. Knox> ;Journal of Investigative Medicine. 2021 Jun 1
2 citations
Atypical Severe Shock-like Reactions in Adolescents After Trimethoprim-Sulfamethoxazole Therapy
Jennifer A Rathe, Nicole M. Poole, Ann J. Melvin> ;Journal of the Pediatric Infectious Diseases Society. 2021 Apr 3
3 citations
Laboratory Diagnosis of Sexually Transmitted Infections in Cases of Suspected Child Sexual Abuse.
Xuan Qin, Ann J. Melvin> ;Journal of Clinical Microbiology. 2020 Jan 28
1 citations
Via media: Role and responsibilities of the independent safety officer
M. E. B. Holbein, Barbara N. Hammack, Ann J. Melvin, Tamsin A. Knox> ;Journal of Clinical and Translational Science. 2019 Aug 1
1 citations
Varicella-Associated Stroke.
Surabhi B Vora, Catherine Amlie-Lefond, Francisco A. Perez, Ann J. Melvin> ;The Journal of Pediatrics. 2018 Apr 19
11 citations
Hepatic, Renal, Hematologic, and Inflammatory Markers in HIV-Infected Children on Long-term Suppressive Antiretroviral Therapy.
Ann J. Melvin, Meredith G. Warshaw, Alexandra Compagnucci, Yacine Saidi, Linda Harrison, Anna Turkova, Gareth Tudor-Williams, Penpact (Penta ), Pactg, Anrs Study Team> ;Journal of the Pediatric Infectious Diseases Society. 2017 Sep 1
15 citations
Decline in CD4 T lymphocytes with monotherapy bridging strategy for non-adherent adolescents living with HIV infection: Results of the IMPAACT P1094 randomized trial
Allison L. Agwu, Meredith G. Warshaw, Elizabeth J. McFarland, George K. Siberry, Ann J. Melvin, Andrew Wiznia, Lee Fairlie, Sandra Boyd, Paul Harding, Hans M. L. Spieg...> ;Plos One. 2017 Jun 12
6 citations
The interaction between equipoise and logistics in clinical trials: A case study
Meredith G. Warshaw, Vincent J. Carey, Elizabeth J. McFarland, Liza Dawson, Elaine J. Abrams, Ann J. Melvin, Lee Fairlie, Hans M. L. Spiegel, Jonathan Jay, Allison L. ...> ;Clinical Trials. 2017 Jan 31
7 citations
Safety and Efficacy of Atorvastatin in Human Immunodeficiency Virus-infected Children, Adolescents and Young Adults With Hyperlipidemia.
Ann J. Melvin, Grace Montepiedra, Lisa Aaron, William A. Meyer, Hans M. L. Spiegel, William Borkowsky, Mark J. Abzug, Brookie M. Best, Marilyn J. Crain, Peggy R. Borum...> ;The Pediatric Infectious Disease Journal. 2017 Jan 1
11 citations
Health Outcomes of International HIV-infected Adoptees in the US
Elizabeth R. Wolf, Sara Beste, Emily Barr, Jenna Wallace, Elizabeth J. McFarland, Mark J. Abzug, Juliana Darrow, Ann J. Melvin> ;The Pediatric Infectious Disease Journal. 2016 Apr 1
17 citations
Research START: A Multimethod Study of Barriers and Accelerators of Recruiting Research Participants
Mark A. Stein, Michele L. Shaffer, Abigail Echo-Hawk, Jody Smith, Ann E. Stapleton, Ann J. Melvin> ;Clinical and Translational Science. 2015 Dec 1
1 citations
Research Recruitment of Adult Survivors of Neonatal Infections: Is There a Role for Parental Consent?
Ann J. Melvin, Kathleen M. Mohan, Anna Wald, Kathryn M. Porter, Benjamin S. Wilfond> ;The American Journal of Bioethics. 2015 Oct 19
8 citations
HIV-1 Drug Resistance and Second-Line Treatment in Children Randomized to Switch at Low Versus Higher RNA Thresholds.
Linda Harrison, Ann J. Melvin, Susan A. Fiscus, Yacine Saidi, Eleni Nastouli, Lynda Harper, Alexandra Compagnucci, Abdel Babiker, Ross E. McKinney, Diana M. Gibb, Gare...> ;Journal of Acquired Immune Deficiency Syndromes. 2015 Sep 1
58 citations
Changing Trends in Complications and Mortality Rates Among US Youth and Young Adults With HIV Infection in the Era of Combination Antiretroviral Therapy
Gayatri Mirani, Paige L. Williams, Miriam Chernoff, Mark J. Abzug, Myron J. Levin, George R. Seage, James Oleske, Murli Purswani, Rohan Hazra, Shirley Traite, Bonnie Z...> ;Clinical Infectious Diseases. 2015 Aug 12
34 citations
Plasma and cerebrospinal fluid herpes simplex virus levels at diagnosis and outcome of neonatal infection.
Ann J. Melvin, Kathleen M. Mohan, Joshua T. Schiffer, Linda Drolette, Amalia Magaret, Lawrence Corey, Anna Wald> ;The Journal of Pediatrics. 2015 Apr 1
16 citations
Using CD4 Percentage and Age to Optimize Pediatric Antiretroviral Therapy Initiation
Dwight E. Yin, Meredith G. Warshaw, William C. Miller, Hannah Castro, Susan A. Fiscus, Lynda Harper, Linda Harrison, Nigel Klein, Joanna Lewis, Ann J. Melvin, Gareth T...> ;Pediatrics. 2014 Oct 1
29 citations
Safety and infectivity of two doses of live-attenuated recombinant cold-passaged human parainfluenza type 3 virus vaccine rHPIV3cp45 in HPIV3-seronegative young children.
Janet A. Englund, Ruth A. Karron, Coleen K. Cunningham, Philip LaRussa, Ann J. Melvin, Ram Yogev, Ed Handelsman, George K. Siberry, Bhavanji Thumar, Elizabeth Schappel...> ;Vaccine. 2013 Nov 19
13 citations
HIV/HBV coinfection in children and antiviral therapy
Sara A Healy, Sonia Gupta, Ann J. Melvin> ;Expert Review of Anti-Infective Therapy. 2013 Mar 1
3 citations
Lipid changes in Kenyan HIV-1-infected infants initiating highly active antiretroviral therapy by 1 year of age
Agnes Langat, Sarah Benki-Nugent, Dalton Wamalwa, Ken Tapia, Evelyn Ngugi, Lara Diener, Barbra A. Richardson, Ann J. Melvin, Grace John-Stewart> ;The Pediatric Infectious Disease Journal. 2013 Jul 1
1 citations
Role for CTSAs in leveraging a distributed research infrastructure to engage diverse stakeholders in emergent research policy development.
Ann J. Melvin, Kelly Edwards, Jason Malone, Laurie Hassell, Benjamin S. Wilfond> ;Clinical and Translational Science. 2013 Feb 1
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Grant Support

Pharmacokinetic &Safety Study Of Protease Inhibitor In Comb In HIV InfectedNational Center For Research Resources2007
Pactg(Pediatric AIDS Clinical Trial Group) 1058 : Pharmacokinetic StudiesNational Center For Research Resources2007
Pactg 1047: Study Of Quadrivalent Human Papillomavirus Virus LIKE Vaccine In HIVNational Center For Research Resources2007
Pharmacokinetic Amp;Safety Study Of Protease Inhibitor In Comb In HIV InfectedNational Center For Research Resources2006
Developmental Regulation Of Interferon GammaEunice Kennedy Shriver National Institute Of Child Health &Human Development1991–1992

Hospital Affiliations

Seattle Children's HospitalSeattle, Washington

AnnJMelvinMD

Dr. Melvin is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Clinical Trials

Publications & Presentations

Grant Support

Hospital Affiliations

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