AnnaMVargheseMD

PubMed

• Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data.
  Madison Darmofal, Shalabh Suman, Gurnit Atwal, Michael Toomey, Jie-Fu Chen, Jason C Chang, Efsevia Vakiani, Anna M Varghese, Anoop Balakrishnan Rema, Aijazuddin Syed, ...> ;Cancer Discovery. 2024 Feb 27
• Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data.
  Madison Darmofal, Shalabh Suman, Gurnit Atwal, Jie-Fu Chen, Jason C Chang, Michael Toomey, Efsevia Vakiani, Anna M Varghese, Anoop Balakrishnan Rema, Aijazuddin Syed, ...> ;Medrxiv. 2023 Sep 10
• 161 citations
  Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer.
  Luis A Rojas, Zachary Sethna, Kevin C Soares, Cristina Olcese, Nan Pang, Erin Patterson, Jayon Lihm, Nicholas Ceglia, Pablo Guasp, Alexander Chu, Rebecca Yu, Adrienne ...> ;Nature. 2023 Jun 1
• 3 citations
  Genomic Biomarkers Associated with Response to Induction Chemotherapy in Patients with Localized Pancreatic Ductal Adenocarcinoma.
  Brett L Ecker, Alice J Tao, Quisette P Janssen, Henry S Walch, Colin M Court, Vinod P Balachandran, Christopher H Crane, Michael I D'Angelica, Jeffrey A Drebin, T Pete...> ;Clinical Cancer Research. 2023 Apr 3
• 4 citations
  Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of "Second Hit" in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma.
  Binbin Zheng-Lin, Michael Rainone, Anna M Varghese, Kenneth H Yu, Wungki Park, Michael Berger, Miika Mehine, Joanne Chou, Marinela Capanu, Diana Mandelker, Zsofia K St...> ;Molecular Diagnosis & Therapy. 2022 Nov 1
• 8 citations
  Stereotactic ablative radiation for pancreatic cancer on a 1.5 Telsa magnetic resonance-linac system.
  Kathryn R Tringale, Neelam Tyagi, Marsha Reyngold, Paul B Romesser, Abraham Wu, Eileen M O'Reilly, Anna M Varghese, Paola Godoy Scripes, Danny N Khalil, Wungki Park, K...> ;Physics and Imaging in Radiation Oncology. 2022 Oct 1
• 8 citations
  Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice.
  Wungki Park, Catherine A O'Connor, Chaitanya Bandlamudi, Daniella Forman, Joanne F Chou, Shigeaki Umeda, Marsha Reyngold, Anna M Varghese, Fergus Keane, Fiyinfolu Balo...> ;Clinical Cancer Research. 2022 Nov 1
• 72 citations
  Ordered and deterministic cancer genome evolution after p53 loss.
  Timour Baslan, John P Morris 4th, Zhen Zhao, Jose Reyes, Yu-Jui Ho, Kaloyan M Tsanov, Jonathan Bermeo, Sha Tian, Sean Zhang, Gokce Askan, Aslihan Yavas, Nicolas Lecomt...> ;Nature. 2022 Aug 1
• 2 citations
  Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer.
  Kenneth H Yu, Jennifer Park, Avni Mittal, Ghassan K Abou-Alfa, Imane El Dika, Andrew S Epstein, David H Ilson, David P Kelsen, Geoffrey Y Ku, Jia Li, Wungki Park, Anna...> ;Cancer. 2022 Aug 1
• 2 citations
  Survival After Induction Chemotherapy and Chemoradiation Versus Chemoradiation and Adjuvant Chemotherapy for Locally Advanced Rectal Cancer.
  Jin K Kim, Michael R Marco, Campbell S D Roxburgh, Chin-Tung Chen, Andrea Cercek, Paul Strombom, Larissa K F Temple, Garrett M Nash, Jose G Guillem, Philip B Paty, Ron...> ;The Oncologist. 2022 May 6
• 185 citations
  Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.
  Bastien Nguyen, Christopher Fong, Anisha Luthra, Shaleigh A Smith, Renzo G DiNatale, Subhiksha Nandakumar, Henry Walch, Walid K Chatila, Ramyasree Madupuri, Ritika Kun...> ;Cell. 2022 Feb 3
• 4 citations
  Induction FOLFIRINOX for patients with locally unresectable pancreatic ductal adenocarcinoma.
  Caitlin A. McIntyre, Noah A. Cohen, Debra A. Goldman, Mithat Gonen, Eran Sadot, Eileen M. O'Reilly, Anna M. Varghese, Kenneth H. Yu, Vinod P. Balachandran, Kevin C. So...> ;Journal of Surgical Oncology. 2021 Oct 31
• 20 citations
  Treatment patterns and survival in patients with early-onset pancreatic cancer
  Joanne F. Chou, Mithat Gonen, Kevin C. Soares, T. Peter Kingham, Anna M. Varghese, William R. Jarnagin, Michael I. D’Angelica, Jeffrey A. Drebin, Eileen M. O'Reilly, A...> ;Cancer. 2021 Oct 1
• 31 citations
  Early-Onset Pancreas Cancer: Clinical Descriptors, Genomics, and Outcomes
  Singh, R., Anna M. Varghese, Isha Singh, Ritu Raj Singh, Siddharth Kunte, Joanne F. Chou, Marinela Capanu, Winston Wong, Maeve A. Lowery, Zsofia K. Stadler, Erin E. Sa...> ;Journal of the National Cancer Institute. 2021 Sep 4
• 53 citations
  A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers.
  Andrea Cercek, Walid K. Chatila, Rona Yaeger, Henry Walch, Gustavo Dos Santos Fernandes, Asha Krishnan, Lerie Palmaira, Anna Maio, Yelena Kemel, Preethi Srinivasan, Ch...> ;Journal of the National Cancer Institute. 2021 Aug 18
• 18 citations
  Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.
  Parisa Momtaz, Catherine A. O’Connor, Joanne F. Chou, Marinela Capanu, Wungki Park, Chaitanya Bandlamudi, Michael F. Berger, David P. Kelsen, Sarah P. Suehnholz, Debya...> ;Cancer. 2021 Aug 5
• 12 citations
  Local Control and Survival After Induction Chemotherapy and Ablative Radiation Versus Resection for Pancreatic Ductal Adenocarcinoma With Vascular Involvement.
  Joshua S. Jolissaint, Marsha Reyngold, Jared Bassmann, Kenneth Seier, Mithat Gonen, Anna M. Varghese, Kenneth H. Yu, Wungki Park, Eileen M. O'Reilly, Vinod P. Balachan...> ;Annals of Surgery. 2021 Jul 16
• 57 citations
  Therapeutic Implications of Germline Testing in Patients With Advanced Cancers.
  Zsofia K. Stadler, Anna Maio, Debyani Chakravarty, Yelena Kemel, Margaret Sheehan, Erin E. Salo-Mullen, Kaitlyn Tkachuk, Christopher J. Fong, Bastien Nguyen, Amanda Er...> ;Journal of Clinical Oncology. 2021 Jun 16
• 84 citations
  Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer.
  Marsha Reyngold, Eileen M. O'Reilly, Anna M. Varghese, Megan Fiasconaro, M. Zinovoy, Paul B. Romesser, Abraham J. Wu, Carla Hajj, John J. Cuaron, R. Tuli, Lara Hilal, ...> ;JAMA Oncology. 2021 May 1
• 9 citations
  Phase 1 cohort expansion study of LY3023414, a dual PI3K/mTOR inhibitor, in patients with advanced mesothelioma.
  Marjorie G Zauderer, Evan W. Alley, Johanna C. Bendell, Enrica Capelletto, Todd M. Bauer, Sophie Callies, Anna M. Szpurka, Suhyun Kang, Melinda D. Willard, Volker Wach...> ;Investigational New Drugs. 2021 Mar 4
• 87 citations
  Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer
  Davide Melisi, Do Youn Oh, Antoine Hollebecque, Emiliano Calvo, Anna M. Varghese, Erkut Borazanci, Teresa Macarulla, Valeria Merz, Camilla Zecchetto, Yumin Zhao, Iveli...> ;Journal for Immunotherapy of Cancer. 2021 Mar 1
• 2 citations
  Leptomeningeal disease in pancreas ductal adenocarcinoma: A manifestation of longevity.
  Catherine A. O’Connor, Jennifer Park, Thomas Kaley, Brie Kezlarian, Marcia Edelweiss, T. Jonathan Yang, Wungki Park, Diane Lauren Reidy, Anna M. Varghese, Kenneth H. Y...> ;Pancreatology. 2021 Feb 6
• 42 citations
  Phase II Single-arm Study of Durvalumab and Tremelimumab with Concurrent Radiotherapy in Patients with Mismatch Repair-proficient Metastatic Colorectal Cancer.
  Neil H. Segal, Andrea Cercek, Geoffrey Y. Ku, Abraham J. Wu, Andreas Rimner, Danny N. Khalil, Diane Reidy-Lagunes, John J. Cuaron, T. Jonathan Yang, Martin R. Weiser, ...> ;Clinical Cancer Research. 2021 Jan 27
• 30 citations
  Clinical Calculator Based on Molecular and Clinicopathologic Characteristics Predicts Recurrence Following Resection of Stage I-III Colon Cancer.
  Martin R. Weiser, Meier Hsu, Philip S. Bauer, William C. Chapman, Iván González, Deyali Chatterjee, Deepak Lingam, Matthew G. Mutch, Ajaratu Keshinro, Jinru Shia, Efse...> ;Journal of Clinical Oncology. 2021 Jan 13
• 4 citations
  Insertion of an Alu-like element in MLH1 intron 7 as a novel cause of Lynch syndrome.
  Yirong Li, Erin E. Salo-Mullen, Anna M. Varghese, Magan Trottier, Zsofia K. Stadler, Liying Zhang> ;Molecular Genetics & Genomic Medicine. 2020 Dec 1
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Lectures

• Young-onset pancreas cancer (PC) in patients less than or equal to 50 years old at Memorial Sloan Kettering (MSK): Descriptors, genomics, and outcomes. 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/24/2020
• Non-invasive detection of acquired resistance to FGFR inhibition in patients with cholangiocarcinoma harboring FGFR2 alterations. 
  2019 ASCO Annual Meeting - 6/1/2019
• A phase I expansion study of trifluridine and tipiracil (FTD/TPI) in combination with irinotecan (IRI) and bevacizumab (BEV) in patients with metastatic colorectal can... 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018