AnneLouiseSchaferMD

Diabetes, Lipid Metabolism

Chief of Endocrinology and Metabolism, San Francisco VA Health Care System; Associate Professor in Residence, University of California, San Francisco

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Office
1700 Owens Street
Room 367
San Francisco, CA 94158
Phone(415) 221-4810 x 24895
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Summary

Dr. Schafer is Chief of Endocrinology and Metabolism for the San Francisco VA Health Care System and Associate Professor of Medicine and of Epidemiology and Biostatistics at UC San Francisco. She is board-certified by the American Board of Internal Medicine in the subspecialty of Endocrinology, Diabetes and Metabolism. Her research focus is osteoporosis and bone metabolism. One of her research emphases is osteoporosis treatment and the assessment of response to osteoporosis therapy. She also studies the relationships between bone, fat, and glucose metabolism, including the effects of obesity and diabetes on bone, and the skeletal regulation of energy metabolism. Currently, she is investigating the effects of bariatric surgery (weight loss surgery) on calcium metabolism and skeletal health. Dr. Schafer's research has been funded by the NIH (National Institute of Diabetes and Digestive and Kidney Diseases), the US Department of Veterans Affairs, and the American Society for Bone and Mineral Research.

Education & Training

UCSFFellowship, Endocrinology, Diabetes and Metabolism, 2007 - 2009
UCSFResidency, Internal Medicine, 2004 - 2007
University of California San Francisco School of MedicineClass of 2004
Harvard UniversityBA

Certifications & Licensure

CA State Medical License 2006 - 2021
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Clinical Trials

Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton Start of enrollment: 2016 Jun 01Anne Schafer, MD
Specialized Centers of Research (SCOR) Kyphosis Study Start of enrollment: 2013 Feb 01Lane, N.E.,Katzman, W.
Effects of Gastric Bypass Surgery on Calcium Metabolism and the Skeleton Start of enrollment: 2011 Jul 01Grunfeld, C.,Schafer, A.L.
Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery
PRebiotic to IMprovE Calcium Absorption Anne Schafer, MD

Publications & Presentations

PubMed

Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery.
Diana Alba, Lucy Wu, Peggy M. Cawthon, Kathleen Mulligan, Thomas Lang, Sheena Patel, Nicole King, Jonathan T. Carter, Stanley J. Rogers, Andrew M. Posselt, Lygia Stewa...> ;The Journal of Clinical Endocrinology and Metabolism. 2019 Mar 1
Leptinemia is Associated With Peripheral Artery Disease.
Zahner, G. J.,Ramirez, J. L.,Spaulding, K. A.,Khetani, S. A.,Gasper, W. J.,Grunfeld, C.,Hills, N. K.,Schafer, A. L.,Grenon, S. M.> ;J. Surg. Res.. 2019 Feb 10
Trunk muscle composition 2 months after hip fracture: Findings from the Baltimore Hip Studies.
Hicks, G. E.,Shardell, M. D.,Miller, R. R.,Eastlack, M.,Orwig, D. L.,Goodpaster, B. H.,Chomentowski, P. J.,Hochberg, M. C.,Rathbun, A. M.,Cauley, J. A.,Harris, T.,Satt...> ;Arch Phys Med Rehabil. 2018 Dec 24
Comparison of BMD Changes and Bone Formation Marker Levels 3 Years After Bisphosphonate Discontinuation: FLEX and HORIZON-PFT Extension I Trials.
Kim, T. Y.,Bauer, D. C.,McNabb, B. L.,Schafer, A. L.,Cosman, F.,Black, D. M.,Eastell, R.> ;J. Bone Miner. Res.. 2018 Dec 12
Serum resistin is associated with impaired endothelial function and a higher rate of adverse cardiac events in patients with peripheral artery disease.
Ramirez, J. L.,Khetani, S. A.,Zahner, G. J.,Spaulding, K. A.,Schaller, M. S.,Gasper, W. J.,Hills, N. K.,Schafer, A. L.,Grenon, S. M.> ;J. Vasc. Surg.. 2018 Oct 08
Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans.
Diana Alba, Jeffrey A Farooq, Matthew Y.C. Lin, Anne L. Schafer, John A. Shepherd, Suneil K. Koliwad> ;The Journal of Clinical Endocrinology and Metabolism. 2018 Sep 1
Bone Health After Bariatric Surgery.
Gagnon, C.,Schafer, A. L.> ;JBMR Plus. 2018 Oct 05
Sex differences in response to targeted kyphosis specific exercise and posture training in community-dwelling older adults: a randomized controlled trial.
Katzman, W. B.,Parimi, N.,Gladin, A.,Poltavskiy, E. A.,Schafer, A. L.,Long, R. K.,Fan, B.,Wong, S. S.,Lane, N. E.> ;BMC Musculoskelet Disord. 2017 Dec 06
Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture Occur Early and Particularly Impact Postmenopausal Women.
Schafer, A. L.,Kazakia, G. J.,Vittinghoff, E.,Stewart, L.,Rogers, S. J.,Kim, T. Y.,Carter, J. T.,Posselt, A. M.,Pasco, C.,Shoback, D. M.,Black, D. M.> ;J. Bone Miner. Res.. 2017 Dec 28
Bone Marrow Fat Changes After Gastric Bypass Surgery Are Associated With Loss of Bone Mass
Tiffany Y. Kim, Ann V. Schwartz, Xiaojuan Li, Kaipin Xu, Dennis M. Black, Dimitry M Petrenko, Lygia Stewart, Stanley J. Rogers, Andrew M. Posselt, Jonathan T. Carter, ...> ;Journal of Bone and Mineral Research. 2017 Aug 9
Serum 25-hydroxyvitamin D level and incident type 2 diabetes in older men, the Osteoporotic Fractures in Men (MrOS) study.
Napoli N, Schafer AL, Lui L, Cauley JA, Strotmeyer ES, Le Blanc ES, Hoffman AR, Lee CG, Black DM, Schwartz AV> ;Bone. 2016-09-01
Decline in Bone Mass During Weight Loss: A Cause for Concern?
Schafer AL> ;J. Bone Miner. Res.. 2016-01-01
Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study
Anne L. Schafer, Xiaojuan Li, Ann V. Schwartz, L.S. Tufts, A.L. Wheeler, Carl Grunfeld, Lygia Stewart, Stanley J. Rogers, Jonathan T. Carter, Andrew M. Posselt, Dennis...> ;Bone. 2015 May 1
Teriparatide treatment of osteoporosis in an HIV-infected man: a case report and literature review.
Wheeler, A. L.,Tien, P. C.,Grunfeld, C.,Schafer, A. L.> ;AIDS. 2014 Dec 24
Panostotic Expansile Bone Disease With Massive Jaw Tumor Formation and a Novel Mutation in the Signal Peptide of RANK
Anne L. Schafer, Steven Mumm, Ivan H. El-Sayed, William H. McAlister, Andrew E. Horvai, Andrea M Tom, Edward C. Hsiao, Frederick V Schaefer, Michael T. Collins, Mark S...> ;Journal of Bone and Mineral Research. 2014 Apr 1
Gastric bypass in obese rats causes bone loss, vitamin D deficiency, metabolic acidosis, and elevated peptide YY.
Canales, B. K.,Schafer, A. L.,Shoback, D. M.,Carpenter, T. O.> ;Surg Obes Relat Dis. 2014 Jun 28
Serum 25-hydroxyvitamin D concentration does not independently predict incident diabetes in older women.
Schafer, A. L.,Napoli, N.,Lui, L.,Schwartz, A. V.,Black, D. M.> ;Diabet. Med.. 2013 Dec 05
The search for the optimal anabolic osteoporosis therapy.
Black, D. M.,Schafer, A. L.> ;J. Bone Miner. Res.. 2013 Oct 12
Postmenopausal women treated with combination parathyroid hormone (1-84) and ibandronate demonstrate different microstructural changes at the radius vs. tibia: the PTH...
Schafer, A. L.,Burghardt, A. J.,Sellmeyer, D. E.,Palermo, L.,Shoback, D. M.,Majumdar, S.,Black, D. M.> ;Osteoporos Int. 2013 Oct
Effects of antiresorptive therapies on glucose metabolism: Results from the FIT, HORIZON-PFT and FREEDOM trials.
Schwartz, A. V.,Schafer, A. L.,Grey, A.,Vittinghoff, E.,Palermo, L.,Lui, L. Y.,Wallace, R. B.,Cummings, S. R.,Black, D. M.,Bauer, D. C.,Reid, I. R.> ;J Bone Miner Res. 2013 Jun
Urine Calcium Excretion, Cardiovascular Events, and Mortality in Outpatients With Stable Coronary Artery Disease (from the Heart and Soul Study).
Welles, C. C., Schafer, A. L., Vittinghoff, E., Shlipak, M. G., Whooley, M. A., Ix, J. H.> ;Am J Cardiol. 2012 Dec 15
Six Months of Parathyroid Hormone (1-84) Administered Concurrently Versus Sequentially with Monthly Ibandronate Over Two Years: The PTH and Ibandronate Combination Stu...
Schafer, A. L., Sellmeyer, D. E., Palermo, L., Hietpas, J., Eastell, R., Shoback, D. M., Black, D. M.> ;J Clin Endocrinol Metab. 2012 Oct
Change in Undercarboxylated Osteocalcin Is Associated with Changes in Body Weight, Fat Mass, and Adiponectin: Parathyroid Hormone (1-84) or Alendronate Therapy in Post...
Schafer, A.L., Sellmeyer, D.E., Schwartz, A.V., Rosen, C.J., Vittinghoff, E., Palermo, L., Bilezikian, J.P., Shoback, D.M., Black, D.M.> ;J Clin Endocrinol Metab. 2011 Dec
Quantification of vertebral bone marrow fat content using 3 Tesla MR spectroscopy: reproducibility, vertebral variation, and applications in osteoporosis.
Li, X., Kuo, D., Schafer, A.L., Porzig, A., Link, T.M., Black, D., Schwartz, A.V.> ;J Magn Reson Imaging. 2011 Apr
Consistency of bone turnover marker and calcium responses to parathyroid hormone (1-84) therapy in postmenopausal osteoporosis.
Schafer, A.L., Palermo, L., Bauer, D.C., Bilezikian, J.P., Sellmeyer, D.E., Black, D.M.> ;J Clin Densitom. 2011-01-01
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Lectures

Metabolic Effects of Bariatric Surgery
ENDO 2019 - New Orleans, LA - 3/23/2019
Bone Health After Bariatric Surgery
ENDO 2019 - New Orleans, LA - 3/23/2019

Press Mentions

BMD Not a Reliable Predictor of Vertebral Fragility Fracture in Older WomenJune 23, 2018 17:03
Clinical Challenges: Osteoporosis Risk After Bariatric SurgeryJune 06, 2018 17:34